Radiographs Of Infants Research Articles

Repeated Pelvic Radiographs in Infants, After Harness Treatment for Developmental Dysplasia of the Hip, Carry Very Low Radiation Risk

ObjectiveThere are no data on the effect of X-Ray irradiation to the vulnerable pelvic organs of babies during DDH follow-up. This study aims to calculate, for the first time, the radiation exposure to infants during follow-up for DDH harness treatment, and thus quantify the lifetime risk of malignancy.MethodsPatients who had completed 5 years’ follow-up following successful Pavlik harness treatment were identified from the hospital DDH database. The radiation dose was extracted from the Computerised Radiology Information System database for every radiograph of every patient. The effective dose (ED) was calculated using conversion coefficients for age, sex and body region irradiated. Cumulative ED was compared to Health Protection Agency standards to calculate lifetime risk of malignancy from the radiographs.ResultsAll radiographs of 40 infants, successfully treated in Pavlik harness for DDH, were assessed. The mean number of AP pelvis radiographs was 7.00 (range: 6–9, mode: 7). The mean cumulative ED was 0.25 mSv (Range: 0.11–0.46, SD: 0.07). This is far lower than the annual ‘safe’ limit for healthcare workers of 20 mSv and is categorised as “Very Low Risk”.ConclusionClinicians involved in the treatment DDH can be re-assured that the cumulative radiation exposure from pelvic radiographs following Pavlik harness treatment is “Very Low Risk”. Whilst being mindful of any radiation exposure in children, this study provides a scientific answer that help addresses parental concerns.

Craniosynostosis Develops in Half of Infants Treated for Hydrocephalus with a Ventriculoperitoneal Shunt.

Craniosynostosis following placement of a ventriculoperitoneal shunt for hydrocephalus has been sporadically described. The purpose of this investigation was to determine the general risk of developing craniosynostosis in this patient population. The authors retrospectively reviewed records and radiographs of infants who underwent ventriculoperitoneal shunt placement for hydrocephalus from 2006 to 2012. Recorded variables included date of shunt placement, demographics, comorbidities, cause of hydrocephalus, shunt type, and number of shunt revisions. Axial computed tomographic images obtained before and immediately after shunt placement and 2 to 4 years after shunt placement were evaluated by a panel of clinicians for evidence of craniosynostosis. Patients with preshunt craniosynostosis, craniosynostosis syndromes, or poor-quality computed tomographic images were excluded. Data were analyzed using STATA Version 15.1 statistical software. One hundred twenty-five patients (69 male and 56 female patients) were included. Average age at shunt placement was 2.3 ± 2.58 months. Sixty-one patients (48.8 percent) developed craniosynostosis at a median of 26 months after shunt placement. Of these, 28 patients fused one suture; the majority involved the sagittal suture (n = 25). Thirty-three patients fused multiple sutures; the most common were the coronal (n = 32) and the sagittal (n = 30) sutures. Multivariable logistic regression identified older age at shunt placement and more shunt revisions as independent predictors of craniosynostosis. Shunt valve type was not significant. Craniosynostosis developed in nearly half of infants who underwent ventriculoperitoneal shunt placement for hydrocephalus. The sagittal suture was most commonly involved. The effect of suture fusion on subsequent cranial growth, shunt failure, or the development of intracranial pressure is unclear. Risk, III.

Utility of Skull Radiographs in Infants Undergoing 3D Head CT During Evaluation for Child Abuse

Utility of Skull Radiographs in Infants Undergoing 3D Head CT During Evaluation for Child Abuse

Utility of skull radiographs in infants undergoing 3D head CT during evaluation for physical abuse

BackgroundClinical practice guidelines recommend performing head CT and skull radiographs (SR) when evaluating infants for physical abuse. We compared the accuracy of 3-dimensional CT (3DCT) and SR for detecting skull fractures. MethodsWe reviewed children <12 months evaluated for physical abuse undergoing 3DCT and SR between January 2017 and December 2018. 3DCT and SR images were blindly read by 2 radiologists. Interrater reliability (IRR) was calculated. Diagnostic accuracy was compared using McNemar's test. Results158 infants with a mean age of 5.0 months underwent 3DCT and SR. Consensus reading identified 46 fractures (29.1%) on 3DCT and 40 fractures (25.3%) on SR. IRR was higher for 3DCT (κ = 0.95) than for SR (=0.65). 11 fractures were identified on 3DCT but not SR. 5 fractures were identified on SR but not 3DCT. There was no difference in the diagnostic accuracy of 3DCT and SR (χ2 = 1.56, p = 0.211). ConclusionsWe found no difference in the accuracy of 3DCT and SR for detecting skull fractures in infants. Because 3DCT has better IRR and evaluates for both bony and intracranial injuries it is superior to SR. Omitting SRs may be acceptable if a 3DCT is performed, and would reduce radiation exposure without compromising diagnostic accuracy.

Avoiding skull radiographs in infants with suspected inflicted injury who also undergo head CT: \u201ca no-brainer?\u201d

ObjectivesTo assess whether head CT with 3D reconstruction can replace skull radiographs (SXR) in the imaging investigation of suspected physical abuse (SPA)/abusive head trauma (AHT).MethodsPACS was interrogated for antemortem skeletal surveys performed for SPA, patients younger than 2 years, SXR and CT performed within 4 days of each other. Paired SXR and CT were independently reviewed. One reviewer analysed CT without and (3 months later) with 3D reconstructions. SXR and CT expert consensus review formed the gold standard. Observer reliability was calculated.ResultsA total of 104 SXR/CT examination pairs were identified, mean age 6.75 months (range 4 days to 2 years); 21 (20%) had skull fractures; two fractures on CT were missed on SXR. There were no fractures on SXR that were not seen on CT. For SXR and CT, respectively: PPV reviewer 1, 95% confidence interval (CI) 48–82% and 85–100%; reviewer 2, 67–98% and 82–100%; and NPV reviewer 1, 95%, CI 88–98% and 96–100%; reviewer 2, 88–97% and 88–98%. Inter- and intra-observer reliability were respectively the following: SXR, excellent (kappa = 0.831) and good (kappa = 0.694); CT, excellent (kappa = 0.831) and perfect (kappa = 1). All results were statistically significant (p < 0.001).ConclusionsCT has greater diagnostic accuracy than SXR in detecting skull fractures which is increased on concurrent review of 3D reconstructions and should be performed in every case of SPA/AHT. SXR does not add further diagnostic information and can be omitted from the skeletal survey when CT with 3D reconstruction is going to be, or has been, performed.Key Points• Head CT with 3D reconstruction is more sensitive and specific for the diagnosis of skull fractures.• Skull radiographs can be safely omitted from the initial skeletal survey performed for suspected physical abuse when head CT with 3D reconstruction is going to be, or has been, performed.

Diagnostic Yield of Routine Skull Radiographs in Infants With Deformational Plagiocephaly.

Differentiating synostotic and nonsynostotic plagiocephaly can be challenging, and many providers routinely obtain screening skull radiographs when evaluating an infant with plagiocephaly. However, the diagnostic yield of radiographs has not been studied in this clinical setting. This study was a retrospective chart review. The study took place in a tertiary care center. We retrospectively reviewed the records of all patients referred to Children's Medical Center (Dallas, TX) between the years 2010 to 2012 with a diagnosis of plagiocephaly. After an initial evaluation, skull radiographs were obtained to rule out craniosynostosis. We reviewed clinical and demographic data and radiographic findings to determine the diagnostic yield of routine screening radiographs in infants presenting with plagiocephaly. There were 1219 patients in total, and 1213 of these patients received screening four-view conventional skull radiographs. Six had computed tomography without prior radiographs. Of the patients in the skull radiograph group, 24% (289 of 1213) had abnormal radiographic findings, and 7.6% of this group (22 of 289) had findings that were indicative of craniosynostosis. Of these 22 patients, 12 obtained follow-up studies, and only three patients (0.2% of skull group) had true craniosynostosis. In comparison, 50% (three of six) in the group of patients who underwent computed tomography without prior conventional screening radiographs had true craniosynostosis. Routine screening skull radiographs have a low diagnostic yield in differentiating between synostotic and nonsynostotic plagiocephaly in patients presenting to a tertiary care deformational plagiocephaly clinic. Considering the costs and radiation exposure, the benefit of the routine use of skull radiographs in patients with deformational plagiocephaly is questionable.

Diagnostic Yield of Cervical Radiographs in Infants with Deformational Plagiocephaly.

When evaluating infants with deformational plagiocephaly, cervical spine radiographs are often acquired along with skull radiographs to exclude segmentation and fusion anomalies as the cause of associated torticollis. The diagnostic yield of cervical spine radiographs has not been evaluated in this clinical setting. The authors retrospectively reviewed the charts of all patients who were referred to the University of Texas Southwestern School of Medicine, Children's Medical Center (Dallas, Texas) with deformational plagiocephaly and torticollis and underwent cervical radiography (anteroposterior and lateral views) from 2010 to 2012. The authors reviewed the radiology reports, and a single experienced pediatric neuroradiologist again reviewed all radiographic studies in which the interpreting radiologist had suggested any bony or soft-tissue abnormality. Patient demographics, perinatal data, and physical examination findings were collected, and descriptive statistics were calculated. There were 730 patients with deformational plagiocephaly and torticollis; 49 of 730 reports (6.7 percent) described an abnormality. Of those with abnormal radiologic reports that were abnormal, 23 (47 percent) described osseous abnormalities, 20 (41 percent) described nonosseous deformities, and six (12 percent) described both. Follow-up studies (computed tomography, magnetic resonance imaging, and repeated radiography) of those with abnormalities showed three infants with true upper cervical spine anomalies that might lead to instability of the cervical spine. There is a low diagnostic yield in ordering cervical radiographs in most patients with deformational plagiocephaly. Although the radiation exposure is low, cervical radiographs add additional cost and may not be warranted as a routine practice in this clinical setting. Diagnostic, IV.

Clinical predictors of radiographic abnormalities among infants with bronchiolitis in a paediatric emergency department.

BackgroundAcute viral respiratory exacerbation is one of the most common conditions encountered in a paediatric emergency department (PED) during winter months. We aimed at defining clinical predictors of chest radiography prescription and radiographic abnormalities, among infants with bronchiolitis in a paediatric emergency department.MethodsWe conducted a prospective cohort study of children less than 2 years of age with clinical bronchiolitis, who presented for evaluation at the paediatric emergency department of an urban general hospital in France. Detailed information regarding historical features, examination findings, and management were collected. Clinical predictors of interest were explored in multivariate logistic regression models.ResultsAmong 410 chest radiographs blindly interpreted by two experts, 40 (9.7%) were considered as abnormal. Clinical predictors of chest radiography achievement were age (under three months), feeding difficulties, fever over 38°C, hypoxia under than 95% of oxygen saturation, respiratory distress, crackles, and bronchitis rales. Clinical predictors of radiographic abnormalities were fever and close to significance hypoxia and conjunctivitis.ConclusionOur study provides arguments for reducing chest radiographs in infants with bronchiolitis. For infants with clinical factors such as age less than three months, feeding difficulties, respiratory distress without hypoxia, isolated crackles or bronchitis rales, careful clinical follow-up should be provided instead of chest radiography.

Radiographic indicators of a shared epiphysis in radial polydactyly.

Thumb epiphyses cannot be visualized on radiographs in infants with radial polydactyly, making it difficult to classify by Wassel type. The purpose of this study was to identify radiographic features that distinguish a separate epiphysis from a shared epiphysis. This may assist in operative planning and establishing prognosis. The charts of 34 radial polydactyly patients treated with surgical reconstruction from 2008 through 2012 were retrospectively reviewed. Measurements of the most proximal bones involved in the duplication, including length, width at shaft, width at base, distance between radial and ulnar thumb, and angle between radial and ulnar thumb, were taken from PA radiographs of the thumb by four blinded individuals. The interclass correlation coefficient was calculated to determine inter-observer reliability. Operative notes were reviewed to distinguish between shared and separate epiphyses. Several indices were created from these measurements. Radiographic measurements showed high inter-observer reliability. There were statistically significant differences between patients with separate and shared epiphyses for indices for the width shaft index, interspace distance, the angle × interspace distance, and the angle × interspace index. Radiographic differences exist between children with separate and shared epiphyses. In patients with shared epiphyses, the radial thumb tends to be smaller, closer to the ulnar thumb, and less divergent. Threshold values were identified for predicting the status of the epiphysis based on the angle × interspace distance and the angle × interspace index. These values may be used to help determine in advance of surgery if a shared epiphysis exists.

A prospective comparison of intestinal sonography and abdominal radiographs in a neonatal intensive care unit

No study reported in the literature comprehensively compares findings on neonatal abdominal radiographs with sonography. To compare the findings on abdominal radiographs and sonograms in infants in intensive care, to better understand how the various intestinal gas patterns on radiographs relate to the spectrum of appearances on sonography and, second, to evaluate the ability of sonography to differentiate necrotizing enterocolitis from other intestinal pathology. We prospectively evaluated sonograms and radiographs, blinded to the other modality and to clinical information. Patients' charts were reviewed by a third blinded reader and used as a reference standard for diagnosis. We made associations between sonographic findings, radiographic intestinal gas patterns and clinical diagnoses. We included 75 infants with gestational ages between 23 weeks and 41 weeks. Sonographic abnormalities were present in infants with all radiographic intestinal gas patterns, including normal patterns. We only saw absent intestinal perfusion and fluid collections on sonography (suggesting intestinal necrosis and sealed perforation) in infants with intestinal dilatation with elongation on radiographs. Separation of intestinal loops on radiographs was most commonly caused by reasons other than intestinal wall thickening. Increased intestinal echogenicity or free fluid with echoes on sonography correlated with a diagnosis of necrotizing enterocolitis, whereas anechoic free fluid correlated with absence of necrotizing enterocolitis. Sonography is complementary to radiographs in infants with suspected intestinal pathology, with a spectrum of appearances seen on each modality. Some sonographic findings either strongly suggest necrotizing enterocolitis or supply evidence against this diagnosis.

Wet diaper artifact

Sir, As I am sure many pediatric radiologists have already noticed in their daily practice, an annoying, mottled radiodense artifact is sometimes encountered superimposed on the inferior aspect of abdominal/pelvic radiographs of infants and babies wearing disposable diapers. Modern disposable diapers are constructed of an absorbent central core that lies between a porous, inner top sheet and an impermeable, outer back sheet. The absorbent core material most commonly used is a superabsorbent polymer (SAP) that holds the liquid in place, thus keeping the baby’s skin dry. I wondered if this material was radioopaque and, therefore, obtained simultaneously exposed radiographs of a dry diaper and a diaper wetted using approximately 40 ml of tap water as the urine substitute (Fig. 1). Only the wet diaper reproduced the peculiar mottled artifact. An excellent web article by Pytlik et al. [1] entitled “Superabsorbent polymers” states that the most commonly SAP is sodium polyacrylate prepared from acrylic acid and a crosslinker. This substance is said to retain “... about 30 times its weight in urine” [2] making these products attractive to consumers. The SAP is not intrinsically radioopaque but retains liquid in such a way as to produce the small clump-like artifact pattern. The article goes into detail regarding the construction and components of disposable diapers, the chemistry of SAPs, the mechanism of fluid absorption and retention, and environmental implications. The “bottom” line is, if you want to avoid artifact, remove wet diapers prior to radiography. Dry diapers are OK. The absence of a diaper represents additional risk beyond the scope of this letter.

Do we need chest radiographs in infants with uncomplicated bronchiolitis?

The question of whether we need routine chest radiographs in infants with uncomplicated bronchiolitis is addressed in an article by Schuh et al from The Hospital for Sick Children, Toronto. They performed a prospective cohort study of more than 200 infants in the pediatric emergency department. The results showed that infants with typical bronchiolitis do not need imaging; invariably, it just confirms the diagnosis. In fact, the use of routine chest radiographs appeared to increase the chances of prescribing antibiotics in patients who were otherwise uncomplicated.

Optimal exposure parameters for digital radiography of the infant skull: A pilot study

To determine optimal exposure parameters when performing digital skull radiographs in infants with suspected non-accidental injury (NAI). Anteroposterior and lateral post-mortem skull radiographs of six consecutive infants with suspected NAI were made at six exposure levels for each projection. Entrance surface doses ranged from 75-351 microGy. Exposures were made with a Fuji 5000R computed radiography system onto a standard resolution imaging plate. In three patients exposures were repeated using a high-resolution imaging plate. Hard copy images with an edge-enhancement factor of 0.5 were produced. Six observers assessed and scored the radiographs from 1=poor to 5=excellent for visualization of five criteria. The criteria scored included outer table of skull vault, inner table of skull vault, suture margins, vascular markings and soft tissues of the scalp. Radiographs were then ranked in order of overall image quality. Film density and sensitivity values were recorded. Local research committee approval was obtained. Current parameters give an average entrance surface dose of 253 microGy and 246 microGy for anteroposterior and lateral radiographs, respectively. The study demonstrated no perceived improvement in image quality above an entrance surface dose of 200 microGy (80% of current dose) or by the use of a high-resolution imaging plate. The potential exists to reduce radiation exposure in infants. A study has commenced to determine the effects of dose reduction on diagnostic accuracy in suspected NAI.

Interpretation of Chest Radiographs in Infants with Cough and Fever

An understanding of the appearance of the infant chest radiograph requires an understanding of the anatomy and the physiologic, immunologic, and pathologic processes in the infant's chest. The authors describe the features of the infant chest that most influence the appearance of the chest radiograph in infants with cough and fever. They discuss why confusion sometimes occurs when radiology residents and general radiologists familiar with adult chest radiographs first evaluate the infant chest radiograph. The radiographic appearance of acute inflammation does not look the same in infants as it does in older children and adults. The hallmark of inflammatory lung disease in the infant chest is air trapping on the chest radiograph.

First-time wheezing in infants during respiratory syncytial virus season: chest radiograph findings.

To evaluate the prevalence of pathologic chest radiographs in infants presenting with a first episode of wheezing during respiratory syncytial virus (RSV) seasons and to compare demographics and clinical variables between patients with benign and pathologic chest radiographs. We conducted a descriptive study of infants presenting to the emergency departments and urgent care centers of two tertiary care children's hospitals. All previously healthy infants aged 0 to 12 months presenting with a first episode of wheezing were eligible. Signs and symptoms were recorded, and then a chest radiograph was obtained. After the completion of the study, all chest radiographs were reviewed by two pediatric radiologists blinded to the child's clinical presentation and diagnosis. Associations between signs and symptoms and chest radiograph findings were evaluated. A total of 140 patients were enrolled. One (0.7%) patient had a cardiac anomaly, and 23 patients (16%) had an infiltrate versus atelectasis. The cardiac anomaly was suspected based on the clinical signs and symptoms present prior to obtaining the chest radiograph. Of the 23 patients with infiltrate/atelectasis, only eight (35%) were febrile, 12 (52%) were tachypneic, and nine (39%) were hypoxemic. Seventeen percent of 140 previously healthy infants presenting with a first episode of wheezing during RSV seasons had a pathologic chest radiograph. However, only one patient (0.7%) had a cardiac anomaly, and all others had chest radiograph findings consistent with a respiratory tract infection.

Understanding chest radiographs of infants and children: the AIR systematic approach

A plain radiograph of the chest is the most frequently requested radiological image in infants and children. Assessing chest radiographs of infants and children can be challenging because of the age-related differences in normal anatomic structures, the effect of inhalation and exhalation during the imaging, and the direction of rotation. An understanding of basic radiographic principles is necessary before beginning to interpret chest films of infants and children. Use of the AIR approach can help nurses begin to understand and assess chest radiographs of infants and children in an orderly and systematic manner.

Quality of ambulatory thoracic radiography in the child--a pilot study

A quality control of outpatient paediatric chest X-rays was conducted in a sample of patients of one paediatric practice. During a period of eight months the technical image quality was analysed considering both diagnostic aspects and radiation protection. The quality of the 139 examined chest X-rays was inadequate concerning the collimation and focussing of the X-rays and the positioning of the patients. Exposure was estimated as average, sharpness was rated as good. In total 14% of the X-rays were not suitable for medical diagnosis. Image quality of the X-rays of infants (children younger than 6 years) was significantly lower compared to the total sample. Radiation protection standards were not fulfilled. As a conclusion from our results, improvements in outpatient paediatric radiography are urgently necessary. Quality control committees should pay particular attention in radiographs of infants.

Positioning the Infant for a Pelvic Radiograph

It can be difficult to take reproducible radiographs of infants’ hips. We have compared antero-posterior pelvic radiographs when the infant's hips are held in flexion or extension. One hundred and fifty radiographs of infants aged 3 to 12 months have been analysed. Radiographic indicators for the diagnosis of developmental dysplasia of the hip and alignment pelvic indicators have been assessed. There were significant differences using the Student t-test analysis for the symphysis-os ischium angle (p&lt;0.0001) and the pelvic tilt index (p=0.0017) between the positions of the infants’ hips on the x-ray table. Twenty degrees of hip flexion increases the pelvic tilt backward (decreased lumbar lordosis). When positioning infants over 3 months old on the x-ray table the neutral antero posterior position is preferable. The pelvic position is more neutral when the hips are extended.

The reliability of measurements of pelvic radiographs in infants.

We have evaluated the reliability of the measurement of radiological indicators in developmental dysplasia of the hip. Three observers each independently assessed 60 pelvic radiographs from infants aged from 3 to 36 months. Errors from the true value of a single measurement made by a single observer (E1), of the average of two measurements by a single observer (E2), and of the average of two single measurements by two different observers (E3) were established for the acetabular index of Hilgenreiner, for the assessment of superior and lateral femoral displacement and for indicators of pelvic alignment. The errors for the assessment of the acetabular index were E1 +/- 5 degrees, E2 +/- 5 degrees, and E3 +/- 3.5 degrees. There was a significant correlation between the presence of an acetabular notch on the radiograph and an increased error in measurement (p = 0.01). Yamamuro's measurement of lateral femoral displacement was more reliable than the Hilgenreiner distance. The errors of indicators of pelvic alignment showed a correlation with the age of the infant; the quotient of pelvic rotation was more reliable after seven months of age (p < 0.0001). The errors of the measurement of the symphysis os-ischium angle tended to increase with age and those of the measurement of the index of pelvic tilt decreased with skeletal maturation (p = 0.002).

Upper airway radiographs in infants with upper airway insufficiency.

Upper airway measurements in nine infants considered to be at risk of upper airway insufficiency, six of whom presented after an apnoeic episode, were compared with measurements taken in two age groups of healthy infants. Paired, inspiratory and expiratory, lateral upper airway radiographs were obtained while the infants were awake and breathing quietly. The radiographs of all nine infants demonstrated narrowing in the oropharyngeal portion of the airway during inspiration and in six infants there was ballooning of the upper airway during expiration. Seven of the nine infants subsequently experienced recurrent apnoeic episodes which required vigorous stimulation to restore breathing. Experience suggests that respiratory phase timed radiographs are a useful adjunct to the evaluation of infants who are suspected of having upper airway dysfunction. They provide information regarding both the dimensions and compliance of the upper airway as well as the site of any restriction.