With the development of modern electronic technology, the electromagnetic environment is becoming increasingly complex, which poses a severe challenge to the normal work of radar, communication and other systems. Polarization sensitive array can more effectively distinguish and suppress interference signals by using polarization information of electromagnetic waves, and improve the signal-to-noise ratio (SNR) and anti-interference ability of the system. Conformal array can be closely attached to the carrier surface, reducing space occupation and improving signal receiving efficiency and accuracy. However, at present, polarization-sensitive conformal arrays still face technical problems in interference suppression, especially in complex electromagnetic environment, how to optimize interference suppression algorithms to improve system performance has become the research focus. In this paper, an adaptive interference suppression algorithm combining spatial-polarization domain processing is proposed. The algorithm digitally processes the received signal, extracts spatial and polarization domain information, constructs the joint feature vector of the signal in spatial and polarization domain, and designs a joint filter in spatial and polarization domain. The minimum mean square error (MMSE) criterion and the least mean square (LMS) algorithm are used to update the weight vector of the filter in real time, enabling the filter to automatically adapt to changes in the electromagnetic environment and achieve optimal interference suppression. Simulation experiments show that the algorithm exhibits good stability and adaptability under different electromagnetic environments, effectively suppressing interference and extracting the desired signal. Compared with traditional interference suppression algorithms based solely on spatial domain, the joint spatial-polarization domain adaptive interference suppression algorithm significantly improves the interference suppression ratio (ISR) and signal-to-interference-plus-noise ratio (SINR) performance indicators, verifying that the introduction of polarization domain information can enhance the effect of interference suppression.