This paper presents the results of Sn radiation transport and activation calculations related to the ITER RC/RTO EU-I design, performed in support of safety and waste management analyses. The activation characteristics (included the clearance levels) have been estimated for the different materials/zones of the equatorial plane up to 10 5 years after plasma operations. The Bonami-XSDNRPM sequence of the Scale 4.4 code system (using Vitamin-ENEA library, based on ENDF/B-VI data) has been used for radiation transport analyses. The ANITA-4M activation code (with FENDL/A-2 and FENDL/D-2 activation and decay data libraries) is used for the activation calculation. The unconditional clearance level data library is based on IAEA-TECDOC-855. First, a sensitivity analysis to optimise the radial spatial meshing for the neutron flux distribution evaluation and, accordingly, for the activation calculation, has been performed. Then, the clearance indexes of vessel and ex-vessel zones/materials have been calculated. The results are presented and discussed. A design option that considers copper instead of superconductor material for TFC winding pack has also been considered and assessed.