To evaluate and compare exposures of the radius using 3 surgical approaches. Our hypotheses were that the anterior flexor carpi radialis approach allows greater exposure of the distal radius than does the volar-ulnar approach, and the extensile flexor carpi radialis approach allows comparable proximal and midshaft exposure of the radius compared with the dorsal Thompson approach. We performed anterior and dorsal exposures of the radius on 10 matched pairs of cadavers (20 forearms) randomly assigned to 1 anterior and 1 dorsal approach. We measured and compared the anatomic features and limits of the anterior flexor carpi radialis approach, volar-ulnar approach to the distal radius, and the dorsal Thompson approach. The anterior flexor carpi radialis approach exposed 3.3 cm of distal radius width, was convertible to an extensile approach proximally, required sacrifice of 3 arterial branches, and was limited by the junction of the radial and ulnar arteries. This approach provided 79% of radius exposure and ended 4.7 cm distal to the radiocapitellar joint. The volar-ulnar approach to the distal radius exposed 3.1 cm of distal radius width. The dorsal Thompson approach sacrificed no arterial branches, provided 69% of radius exposure, was limited by the first compartment distally and the posterior interosseous nerve proximally, and ended within 2.6 cm of the radiocapitellar joint. The posterior interosseous nerve coursed 19, 14, and 6 mm dorsolateral to the distal, middle, and proximal margins, respectively, of the supinator insertion on the radius. The volar-ulnar approach provided less access to the radial styloid and was not as extensile as the flexor carpi radialis approach. The Thompson approach provided more proximal exposure than the flexor carpi radialis approach. Improved knowledge of the anatomy, limits of exposure, and comparison of features between approaches to the radius may facilitate surgical planning and exposure.