Self-priming centrifugal pump are a type of drainage and irrigation equipment applied in crop irrigation, urban landscaping, dust prevention and cooling, and building water supply. At present, single-stage self-priming centrifugal pumps dominate the pump market. Hence, the market share for multistage self-priming pumps, which can provide high-pressure liquid, is barely adequate. Self-priming time is an important parameter that measures the self-priming performance of multistage self-priming centrifugal pumps. Although many studies have focused on the influences of a single factor on the self-priming time of single-stage self-priming centrifugal pumps, only a few have discussed the self-priming time of multistage self-priming pumps. In the current work, we conducted an experimental study that combined the orthogonal, grey correlation, and self-priming time tests to investigate the influencing factors of the self-priming time of a multistage self-priming centrifugal pump and shorten the corresponding self-priming time. The outlet width of the impeller blade, the radial gap between the impeller and the diffuser, the area of backflow hole, and the number of stages of the multistage self-priming centrifugal pump were selected as the influencing factors in the orthogonal test. The orthogonal analysis of the self-priming time of the multistage self-priming centrifugal pump was conducted, and the results were used as the basis in obtaining the order of importance of all influencing factors through the grey correlation test. Results demonstrate that self-priming time increases gradually with an increase in impeller blade outlet width but that it decreases continuously with an increase in stage number and area of backflow hole. As radial gap increases, self-priming time increases and then decreases. In summary, the area of backflow hole is the most important influencing factor of self-priming time of the multistage self-priming centrifugal pump, followed by impeller blade outlet width, radial gap, and stage number. These findings provide important references for shortening the self-priming time of multistage self-priming centrifugal pumps. Keywords: Multistage self-priming centrifugal pump, Grey correlation test, Orthogonal test; Self-priming time rrelation test, Bomba centrífuga autocebante multietapa, Ensayo de correlación Grey, Ensayo orthogonal, Ensayo de rrelación de tiempo autocebante
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