Introduction: Prior investigations assessing the impact of race and ethnicity on outcomes after mitral valve surgery have reported conflicting findings. The aim of this analysis was to examine the association of race with characteristics and outcomes for patients undergoing mitral and tricuspid valve (MV; TV) surgery using a representative statewide database. Methods: We performed retrospective analyses on 5,929 patients (2,707 female, median age 63 yrs) who underwent MV ( n =4,490, 76%), TV ( n =473, 8%), or both MV and TV ( n =966, 16%) surgery in a statewide collaborative of 10 centers from 2012-2020. The influence of race/ethnicity on preoperative characteristics, MV and TV repair rates, and postoperative outcomes was assessed for White ( n =4,208, 71%), Black ( n =1,261, 21%), Hispanic ( n =140, 2%), Asian ( n =169, 3%), and mixed/other race ( n =151, 3%) patients. Results: Black patients, compared to White patients, had a higher Society of Thoracic Surgeons predicted risk of morbidity or mortality (24.5% vs 13.1% P <0.001) with a higher incidence of previous valve operations, myocardial infarction, stroke, hypertension, diabetes, and chronic lung disease. Compared to White patients, Black and Hispanic patients were less likely to undergo an elective procedure (White 71%, Black 55%, Hispanic 58%, P <0.001). Degenerative MV disease was more prevalent in White patients (White 62%, Black 41%, Hispanic 43%, Asian 51%, mixed/other 45%, all P <0.05) while rheumatic disease was more prevalent in non-White patients (Asian 28%, Hispanic 26%, mixed/other 25%, Black 17%, White 10%, all P <0.05). Repair for degenerative MV disease was more prevalent in White vs Black patients (84% vs 74%, P <0.001), but after multivariable adjustment race was no longer associated with MV repair ( P =0.073). In multivariable analyses, adverse postoperative outcome incidences were not different by race groups, including mortality. Conclusions: Patient race/ethnicity affects the burden of comorbidities at the time of presentation for operation and MV disease etiology. Strategies to improve early detection and referral for surgery and to decrease rates of rheumatic disease for racial and ethnic minority patients with MV and TV disease may enhance outcomes.
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