RACE Experiment Research Articles

The model of acoustic disturbances in atmosphere and ionosphere for mill rate explosion

Study of propagation of high-altitude acoustic pulse from underground and surface explosions, earthquakes is of interest, as -these waves can affect ionosphere. Besides, these investigations allow to work out ionospheerc methods of control of explosions and earthquakes. To investigate the propagation of acoustic pulse from the earth surface through the atmosphere to high-altitude it is necessary to know an initial shape and the evolution model of acoustic pulse. Using Mill Race explosion measurements, we developed model to describe the propagation of an acoustic pulse from the initial wavefront to the ionospheric altitude and analytic shape of initial acoustic pulse (modified Reed's shape). Model calculations were compared with acoustic parachute (for altitude about 10 km) and Doppler shift measurements (for altitude from 150 to 260 km) during Mill Race experiment. The results of this comparison has shown that our calculations are more adequate to experiment than the same theoretical calculations of other authors.

A Novel, Testis-specific mRNA Transcript Encoding an NH2-terminal Truncated Nitric-oxide Synthase

mRNA diversity represents a major theme of neuronal nitric-oxide synthase (nNOS) gene expression in somatic cells/tissues. Given that gonads often express unique and biologically informative variants of complex genes, we determined whether unique variants of nNOS are expressed in the testis. Analysis of cDNA clones isolated from human testis identified a novel, testis-specific nNOS (TnNOS) mRNA transcript. A predicted 3294-base pair open reading frame encodes an NH2-terminal truncated protein of 1098 amino acids. Measurement of calcium-activated L-[14C]citrulline formation and nitric oxide release in CHO-K1 cells stably transfected with the TnNOS cDNA indicates that this protein is a calcium-dependent nitric-oxide synthase with catalytic activity comparable to that of full-length nNOS. TnNOS transcripts exhibit novel 5' mRNA sequences encoded by two unique exons spliced to exon 4 of the full-length nNOS. Characterization of the genomic structure indicates that exonic regions used by the novel TnNOS are expressed from intron 3 of the NOS1 gene. Although lacking canonical TATA and CAAT boxes, the 5'-flanking region of the TnNOS exon 1 contains multiple putative cis-regulatory elements including those implicated in testis-specific gene expression. The downstream promoter of the human nNOS gene, which directs testis-specific expression of a novel NH2-terminal truncated nitric-oxide synthase, represents the first reported example in the NOS gene family of transcriptional diversity producing a variant NOS protein.

SST: Commercial Race or Technology Experiment?

SST: Commercial Race or Technology Experiment?