Quince Seeds Research Articles

Quince Seed Mucilage Mediated Biosynthesis of Gold Nanoparticles: Analysis of Its Anti-prostate Cancer and Antioxidant Properties

Quince Seed Mucilage Mediated Biosynthesis of Gold Nanoparticles: Analysis of Its Anti-prostate Cancer and Antioxidant Properties

Bio-based films from quince by-products: A sustainable alternative for biodegradable food packaging

Quince (Cydonia oblonga Miller) is a seasonal fruit that is commonly processed by the food industry to produce marmalades, jellies and wines, resulting in a large amount of by-products. The filmogenic capacity of quince seeds has been well studied in the literature, but not that of the entire by-product generated in the industry. This work addresses the study of the filmogenic capacity of these by-products, at two formulation levels (QW1 and QW2), and compares them with that of only seeds (QS) in terms of physicochemical, optical, mechanical, morphological, antioxidant and thermal properties. The yield of mucilage obtained from both by-product formulations doubled the obtained from isolated seed (22–27 % vs. 10.9 %) and showed higher tensile strength (106–107 % vs. 85.3 %) and elongation at break values (2–3 vs. 1.9 MPa). The three types of films showed excellent protection properties against UV radiation, attractive optical properties and good DPPH radical scavenging capacity (34–37 %). Microstructural changes over time in the morphology of the three films were also observed by scanning electron microscopy between 24 and 48 h.

The Effects of Quince Seed Jelly and Human Milk on Nipple Fissures During Early Postpartum

Purpose: In experimental studies, it has been reported that the jelly made from the quince seed is effective in healing wounds and has no side effects or contraindications. This study was conducted to determine the effect of quince seed jelly and human milk, respectively, used in the early postpartum period, on nipple fissures. Material and Methods: The research was a randomised controlled study. In total, 426 mothers who met the research criteria were selected for the study, which was conducted at the obstetrics and gynaecology department of two hospitals between 2015–2017 in Sivas city of Turkey. The 426 mothers were distributed equally into three groups (n=142 per group): the human milk, quince seed jelly and the control group. Mothers in the intervention groups applied quince seed jelly and human milk, respectively, on their nipples and areola after every breastfeeding. All mothers were evaluated for nipple fissures on the 1st, 3rd, 7th, and 10th days postpartum. Results: Mothers with the highest number of problems in the first 10 days postpartum belonged to the control group (61.3%-62%), followed by the human milk group (19%), whereas, the quince seed group experienced the least problems (2.8%-5.6%, p

Phytochemicals in recovered seed oils from by‐products of common quince (Cydonia oblonga) and Japanese quince (Chaenomeles japonica)

AbstractNearly 100% of Japanese quince (Chaenomeles japonica) and common quince (Cydonia oblonga) fruits are processed. It generates large amounts of seeds. One of the possible utilization of seeds is oil recovery. Seeds of both quinces were tested for their oil recovery using two methods—solvent‐free protocol by mechanical press and ultrasound‐assisted extraction (UAE) applying n‐hexane, and phytochemistry of obtained oils was studied. The oil yield was nearly twice higher from common quince than Japanese quince (20.9% and 11.2%, respectively) for UAE. Compared to UAE, screw‐pressed allowed for 67% oil recovery. In general, the phytochemical profile of both quince seed oils was similar with some differences in the content of individual compounds. The two quince seed oils were dominated by the same molecules in different compound groups: fatty acids—linoleic acid; tocochromanols—α‐tocopherol; phytosterols—β‐sitosterol, and triterpenoid—squalene. Common quince seed oil was richer in tocochromanols, squalene, and linoleic acid, whereas Japanese quince seed oil was richer in phytosterols. The present study showed the oil potential of fruit industry by‐products and the relatively high oil recovery by the environmentally friendly/healthy technique of extraction (solvent‐free) to achieve ultimately high‐quality products in a “Natural‐Safe‐Green” strategy.Practical applications: Production of fruit each year, especially those used for processing, for example, common quince (C. oblonga), has been increasing in recent years, likely, so has processing and amounts of generated by‐products, including seeds. To reduce the costs, CO2 emissions, and other environmental safety aspects of production, different techniques of plant oil recovery are considered. The extraction method affects oil yield as well as its phytochemical composition. The generated information in the present study can contribute to improved effectiveness of the use of plant material thereby providing environmental, health, and economic benefits.

Biosynthesis of Gold Nanoparticles Using Quince Seed Water Extract and Investigation of Their Anticancer Effect Against Cancer Cell Lines.

In this study, gold nanoparticles (Au-NPs) were synthesized using HAuCl4 and quince seed mucilage (QSM) extract, which was characterized by conventional methods including Fourier transforms electron microscopy (FTIR), UV-Visible spectroscopy (UV-Vis), Field emission electron microscopy (FESEM), Transmission electron microscopy (TEM), Dynamic light spectroscopy (DLS), and Zeta-potential. The QSM acted as reductant and stabilizing agents simultaneously. The NP's anticancer activity was also investigated against osteosarcoma cell lines (MG-63), which showed an IC50 of [Formula: see text]/mL.

Exploring the use of quince seed mucilage as novel coating material for enhancing quality and shelf-life of fresh apples during refrigerated storage

Valorisation of quince seeds was performed for the extraction of mucilage.

Technological aspects of growing promising seed rootstocks for pears based on common quince selection VNIISPK

The article presents the results of agrotechnical research to optimize the technology of growing intensive-type seed stocks based on quince of ordinary VNIISPK breeding and improving the quality of grown seedlings in nursery conditions in order to intensify the production of pear varieties in Central Russia. Based on the conducted research, it was found that the seed productivity of quince of ordinary selection of VNIISPK is almost 8-10 times higher than that of pear, which is most often used as a seed stock in the central part of Russia. Selected forms of quince of ordinary selection of VNIISPK are quite hardy, able to grow and bear fruit in the conditions of the Orel region and can be used as seed rootstocks of pears. Technological methods of preliminary preparation and stratification of quince seeds and methods of growing seed crops for pears in artificial ridges have been developed and optimized. The advantage of using artificial ridges for growing quince seedlings in nursery conditions is shown. Experimentally selected the most reasonable methods of growing common quince, seed sowing schemes, timing and optimal stages of seed development for sowing, providing the best germination rates and the highest yield of seed rootstocks. Based on the obtained research results, a technological scheme is proposed for growing seed rootstocks of the intensive type of VNIISPK breeding in a nursery for the subsequent propagation of pear varieties using intensive technologies in the conditions of the middle zone of Russia.

Development of an Innovative Optoelectronic Nose for Detecting Adulteration in Quince Seed Oil.

In this study, an innovative odor imaging system capable of detecting adulteration in quince seed edible oils mixed with sunflower oil and sesame oil based on their volatile organic compound (VOC) profiles was developed. The system comprises a colorimetric sensor array (CSA), a data acquisition unit, and a machine learning algorithm for identifying adulterants. The CSA was created using a method that involves applying a mixture of six different pH indicators (methyl violet, chlorophenol red, Nile blue, methyl orange, alizarin, cresol red) onto a Thin Layer Chromatography (TLC) silica gel plate. Subsequently, difference maps were generated by subtracting the "initial" image from the "final" image, with the resulting color changes being converted into digital data, which were then further analyzed using Principal Component Analysis (PCA). Following this, a Support Vector Machine was employed to scrutinize quince seed oil that had been adulterated with varying proportions of sunflower oil and sesame oil. The classifier was progressively supplied with an increasing number of principal components (PCs), starting from one and incrementally increasing up to five. Each time, the classifier was optimized to determine the hyperparameters utilizing a random search algorithm. With one to five PCs, the classification error accounted for a range of 37.18% to 1.29%. According to the results, this novel system is simple, cost-effective, and has potential applications in food quality control and consumer protection.

Evaluation of Various In-vitro Biological Activities of Crude Quince Seed Ethanolic Extract

Evaluation of Various In-vitro Biological Activities of Crude Quince Seed Ethanolic Extract

Exploring the Antimicrobial Activity of Quince Seeds Extracted by Two Different Methods

Exploring the Antimicrobial Activity of Quince Seeds Extracted by Two Different Methods

Assessment of the Effects of Quince Seed Mucilage and Wheat Germ Oil on Wound Healing in Rats

Objective: People have used traditional herbal medicines for wound care since the dawn of time. This study aimed to assess the cutaneous wound healing effects of wheat germ oil (WGO) and quince seed mucilage (QSM) in rats.
 Methods: Adult female Wistar albino rats were allocated to one of the three groups: rats treated with topical WGO (n=6); topical QSM (n=6); and topical saline (n=6) as the control group. Two circular, full-thickness wounds of 0.6 mm diameter were created on the dorsal thoracic region of each rat. Test and control solutions were applied twice daily for 14 days. Wound healing was assessed by measuring the wound contraction rate and the time needed for complete epithelialization.
 Results: When compared with the control group, rats in the WGO group had reduced wound closure rates in the first four days, but considerably greater rates in the 8th, 10th, and 12th days, as well as a shorter duration of time needed to complete epithelialization (11 days vs. 13 days). The wound closure rates of the rats in the QSM group were not substantially different from the control rats and the duration of time needed for complete epithelialization was not significantly different from the control group. 
 Conclusion: WGO use has been shown to improve wound healing. It may be used as an alternative or complementary approach for wound treatment depending on the severity of the wounds. On the other hand, QSM was not found to improve wound healing.

Processing waste: bioactive components and antioxidant capacity of cold-pressed oils from some fruit seeds

In this study, the possible use of seeds after fruit processing to obtain unconventional cold-pressed edible oil was investigated. For this purpose, seeds of quince, sour cherries and plum were used. Fatty acid composition, antioxidant activity, peroxide and acid value, oxidative stability, and tocopherols and phytosterols content were determined in the studied oils. Plum seed oil was dominated by oleic acid, while quince and sour cherry seed oils contained abundant linoleic acid. The total polyphenol content in the studied oils ranged from 2.28 to 9.03 mg GAE 100 mL-1. Antioxidant properties (ABTS, DPPH, FRP) were associated with tocopherol content. All three studied oils were rich in β-sitosterol. The oxidative stability of the studied oil samples varied and ranged from 1.92 h-31.17 h. Quince seed oil had the highest content of α-tocopherol (44.30 mg 100 g-1) and plum seed oil had the lowest (3 mg 100 g-1), while sour cherry seed oil had the highest content of β+γ-tocopherol (17.19 mg 100 g-1). The results show that oil from quince, sour cherry, and plum seeds is suitable for the production of a high quality cold-pressed oil. The use of this type of waste from fruit processing contributes to waste reduction and promotes the circular economy.

Exploration of curcumin-incorporated dual anionic alginate-quince seed gum films for transdermal drug delivery

The idea of combining bioextracted polymers for wound healing applications has emerged in hopes of developing highly flexible and mechanically stable hydrogel films with controlled drug delivery, biocompatibility, and high collagen deposition. In the present research, polysaccharide films composed of Alginate and Quince Seed Gum (QSG) were fabricated by ionic crosslinking, and their potential for curcumin delivery and wound healing were examined. In this regard, microstructure, mechanical properties, thermal stability, physiochemical properties, and biocompatibility of films with three different QSG amounts (25 %, 50 %, and 75 %) were studied. Because of the optimum properties of 25 % QSG films like better transparency (Opacity = 6.1 %), higher flexibility (Elongation = 28.9 %), less water solubility (Water solubility = 66.6 %), proper absorbance (Swelling degree = >600 %), and suitable biocompatibility (Cell viability = >85 %), they were used for drug delivery examination. Curcumin administration through films with and without stearic acid modification was investigated. Stearic Acid (SA) modified samples demonstrated superior compatibility between hydrophobic drug and hydrophilic film. Stearic acid-modified film could prolong the curcumin release up to 48 h and showed increased collagen synthesis and TGF-β expression, making it an excellent candidate for transdermal drug delivery and wound healing applications.

Distinguishing Seed Cultivars of Quince (Cydonia oblonga Mill.) Using Models Based on Image Textures Built Using Traditional Machine Learning Algorithms

Different cultivars of seeds may have different properties. Therefore, distinguishing cultivars may be important for seed processing and product quality. This study was aimed at revealing the usefulness of innovative models developed based on selected image textures built using traditional machine algorithms for cultivar classification of quince seeds. The quince seeds belonging to four cultivars ‘Uspiech’, ‘Leskovac’, ‘Bereczki’, and ‘Kaszczenko’ were considered. In total, 1629 image textures from different color channels for each seed were extracted from color images acquired using a flatbed scanner. Texture parameters were used to build models for a combined set of selected textures from all color channels, sets of selected textures from color spaces RGB, Lab, and XYZ, and individual color channels R, G, B, L, a, b, X, Y, and Z using algorithms from different groups. The most successful models were developed using the Logistic (group of Functions), IBk (Lazy), LogitBoost (Meta), LMT (Trees), and naïve Bayes (Bayes). The classification accuracy reached 98.75% in the case of a model based on a combined set of textures selected from images in all color channels developed using the Logistic algorithm. For most models, the greatest misclassification of cases was observed between seeds ‘Bereczki’ and ‘Kaszczenko’. The developed procedure can be used in practice to distinguish quince seeds in terms of a cultivar and avoid mixing seed cultivars with different properties intended for further processing.

Gel properties of the gum from Chinese quince (Chaenomeles sinensis) seeds

The effect of pH and different types and concentrations of salt ions on the gel properties of gum extracted from Chinese quince seeds (CQSG) were investigated by analysing the texture, flow behaviour, water-holding capacity (WHC), zeta potential, and thermal and morphological properties of the gels formed by the gum. Results indicated that the pH and different types and concentrations of ions significantly affected the properties and microstructure of the CQSG gels. However, the various conditions had no obvious effects on the gelling and melting temperatures of the CQSG gels. The effects of the tested salt ions on the WHC of the CQSG gels exhibited different patterns. The zeta potential value increased continuously from -45 to -53 mV with increasing phosphorus concentration, while the presence of CaCl2 caused a continuous decrease in the zeta potential from -35 mV (0.2 wt%) to -22 mV (2 wt%). The present work provides fundamental data for designing novel gelling agents based on gum from Chinese quince seeds for use in processed food.

Sensory and Biological Activity of Medlar (Mespilus germanica) and Quince ‘Nivalis’ (Chaenomeles speciosa): A Comperative Study

This research investigates the potential health benefits of extracts from the seeds, peels, and pulps of quince, medlar, and bletting medlar fruits. Our study reveals that the polyphenol content is higher in the skin than in the flesh of the fruits tested, with the highest concentration found in the skin of fresh medlar fruits (1148 mg GAE/100 gDM). The extracts from medlar and quince show the highest antioxidant activity (ABTS, DPPH, and FRAP tests), while the pulp of bletting medlars exhibits the highest inhibition ability against α-amylase (53.7% at a concentration of 10 mg/mL). The analysis of fatty acids in the tested samples indicates the presence of nine major fatty acids, with linoleic acid being the most abundant (716–1878 mg/100 g of biomass). Analysis of sterols in the tested material shows five main phytosterols, with β-sitosterol being the most commonly studied and recommended phytosterol. The highest amount of phytosterols is found in the lipid fraction of the quince seeds (1337.1 mg/100 g of biomass). Therefore, we suggest that fruit peel extracts can be utilised as a natural source of antioxidants and as an alternative treatment for carbohydrate uptake disorders. However, it is important to note that bletting medlar loses a significant amount of polyphenols and antioxidant activity after the bletting process. This article also describes the sensory analysis process, which is a valuable tool for evaluating the quality of food products. Our study evaluates the attributes and preferences of the fruits of quince, medlar, and bletting medlar using a nine-point hedonic scale. The results show that quince is the highest-rated fruit in terms of aroma, colour, and overall acceptability (7.3, 7.0, and 4.2, respectively) while bletting medlar is the least preferred fruit. The article concludes that sensory analysis can aid in the development of new products and recipes that meet consumer preferences. In general, the study suggests that both fruit peel extracts and sensory analysis are important tools for assessing product quality and developing products that meet consumers’ preferences.

Evaluation of the Effect of Quince Seed Extract On Physical and Sensorial Properties of Gluten-Free Cake Batter Formulations

Celiac disease is a serious and lifelong disorder that is associated with gluten consumption. Celiac patients should commit to a strict gluten free diet. Besides celiac patients, gluten can also cause allergenic reactions in a significant portion of population. Thus, there is a growing trend in replacing sources of gluten with alternatives. This work concentrated on improving the quality and consumer acceptance of gluten-free cakes made out of rice flour by using quince seed extract, which is a unique hydrocolloid product that exhibits emulsification properties. The cake batter and cooked cakes were characterized in terms of water activity, color, porosity, emulsion stability, textural properties, rheological behavior and sensorial attributes. Emulsion stability results indicated an excellent improvement of physical stability of batter emulsions by addition of quince seed extract (QSE) and lecithin, which was identified with no visible phase separation in samples Q0.1E and Q0.2E. All cake batters displayed a pseudoplastic flow behavior with apparent viscosities and shear thinning behavior increasing substantially with increasing QSE concentrations. Hardness values gathered from texture profile analysis, implied that best cake texture was obtained via QSE and lecithin incorporation. Sensory analysis results also supported the same result in that, samples with egg yolk and QSE both, yielded a more preferable appearance and texture. Therefore, with this study, it was possible to observe the promising effects of QSE incorporation on cake batter and baked cake properties.

Polyelectrolyte Complexes Between Chitosan and Quince Seed Gum: A Rheological, Structural, and Multiple Dye Adsorption Study

Polyelectrolyte Complexes Between Chitosan and Quince Seed Gum: A Rheological, Structural, and Multiple Dye Adsorption Study

Computational identification of bioactive compounds from Cydonia oblonga Mill. against hepatocellular carcinoma by targeting pTEN and HBx-interacting protein.

Phytochemicals derived from Cydonia oblonga have been investigated for their anti-oxidant and anti-cancer activities in various cancer cell lines. The reported bioactive compounds are evaluated in silico to develop a novel antagonist against pTEN (phosphatase and tensin homolog) and HBx (hepatitis B X-interacting protein) to target hepatocellular carcinoma. Lower expression of pTEN or higher expression of HBx represents the progression of hepatocellular carcinoma. This research is intended to identify the best candidate who interacts with our target proteins (pTEN and HBx) from the quince seeds by using computational methodologies. The ternary structures of the proteins and phytochemicals are retrieved from the online databases (RCSB and PubChem). The drug likeness analysis of the reported seventeen compounds was done, but only five follow the selection criteria. ADMET profiling of these five compounds was done, followed by docking analysis and molecular dynamics study of the best complexes to determine the stability of the complexes. A docking study revealed that caffeoylquinic acids (CQA) derivatives have the significant inhibitory potential of 3-O-caffeoylquinic acid (3CQA) and 5-O-caffeoylquinic acid (5CQA) with binding affinity of - 7.53 and - 7.49 against pTEN and - 5.94 and - 6.01 against HBx in comparison to the doxorubicin. The average root mean square deviation and root mean square fluctuation values for protein-ligand complexes were found quite stable compared to the standard, while parameters like gyration and SASA (solvent-accessible surface area) supported the complexes significant binding and stability. The results obtained from the evaluation show that 3CQA and 5CQA havethe best stability, especially with the pTEN protein target. Hence, these compounds have to be considered for detailed experimental studies to understand their biological function against hepato-carcinoma.

Formulation and evaluation of quince seeds mucilage – sodium alginate microspheres for sustained delivery of cefixime and its toxicological studies

Quince seed mucilage was used in a combination of sodium alginate to develop sustained-release microspheres of cefixime. Physical characterizations such as FTIR, TGA, DSC, and SEM were performed on the prepared microspheres. The swelling of microspheres was maximum at pH 7.4 and reduced at acidic pH. The average particle size ranged from 679 µm ± 0.21 to 810 µm ± 0.31, while the drug encapsulation efficiency range was found as 73.76 ± 0.24–85.63 ± 0.46. In vitro release profile of QSM-alginate-cefixime microspheres followed Korsmeyer-Peppas model (R 2 = 0.9732-–0.9946); and release was non-Fickian as we found value of n > 1. This study reveals the benefits of QSM-alginate microspheres for the sustained release of cefixime without any toxicity and it also improved antibacterial properties.