Real Question Research Articles

Heidegger on deep time and being-in-itself: introductory thoughts on “The Argument against Need”

ABSTRACT The article provides an introduction to Heidegger's manuscript “The Argument against Need”. It comments on the nature of the manuscript, the circumstances of its composition, and its major philosophical themes. These themes include the problem of ontological independence, the nature of time, and the question of realism.

Performance Analysis of Various 5G Mobile Architectures

The field of Telecommunication has progressed and emerged to be a successful field of technology. From communicating via pigeons and cannon balls to video conferencing for a meeting, the communication has improved surpassing every user’s expectation. With the introduction of wireless communication, the field of communication took a different turn. Just when we thought we reached the zenith of wireless communication, an esoteric concept of StandAlone (S.A.) and Non-StandAlone (N.S.A.) opened the gates to a more efficient communication, expanding the horizons of technology. The 5G network has started developing over some regions in the world but the real question remains; which is, whether an efficient communication is worth the economy spent on developing it or certain advantages of this networks should be given up to protect the country’s economy.The 3rd Generation Partnership Project (3GPP) presents two essential architecture for 5G deployment from LTE: Non-Standalone (NSA) and Standalone (SA). NSA empowers quick 5G benefit arrangement with minimum investment by leveraging the existing LTE infrastructures. SA comprises of a single Radio Access Technology (RAT), meaning it is conceivable to supply full 5G upgrades designed to work only in the 5G New Radio (NR) This analytical paper elaborates the performance of these two architectures for the implementation of 5G cellular technology, where in the first one would be highly technology centric approach with less cost efficiency and the other one would be the economy savvy aspect with little bit negotiation with technology upgrades

The De-Gentrification of New Markets Tax Credits

"I am concerned and I am frustrated because I don't know what the alternates are...It clearly isn't racist; its economics. The real question you have to ask yourself is: Is this good orbad?"-Norman Rice, former Mayor of Seattle, On gentrification in that cityUrban America is in a state of crisis. A huge pool of America's resources is increasingly disconnected from mainstream society. That pool is within the core of major cities and particularly includes African American and Hispanic male youth. By way of illustration, more than half of all core city African American men do not finish high school. The correlation between drop-out rates, unemployment, and incarceration is profound. As of 2004, 72% of African American dropouts who are in their 20's are unemployed, up from 65% in 2000.s Incarceration levels are at historic highs and increasing, where by their mid-30's, 6 in 10 of these high school drop outs have spent time in prison. That rate is four times higher than that of Black men in South Africa under the apartheid regime. Seventy-five percent of African American males incarcerated in Baltimore Maryland did not graduate from high school. The infant mortality rate among all African Americans is more than twice the national average, and is much worse among the poor in the core of urban America. After the Katrina floodwatershave receded, some see an opportunity to buy low and sell high. But themuted voices of the poor cry to keep what they had.' For them it was aKatrina moment. For the urban core poor across the nation, it has been aKatrina erosion over the decades from a series of unnatural disasters.

NMOSD: How Long to Treat

Introduction: Neuromyelitis optica spectrum disorder (NMOSD) is a debilitatively relapsing autoimmune neurological disorder affecting young adults. With the advent of steroids, plasma exchange and immunomodulator therapy, the course of the disorder can be controlled up to a comprehensive extent. But the real question is: how long?

Peircean realism: A primer

AbstractCharles S. Peirce's realism has been neglected by pragmatists and critical realists alike in the current debate over metatheoretical realism in sociology. This paper introduces Peirce's view of what is at stake in the question of realism, specifically regarding causation. Leveraging current interest in Peirce's conception of abduction, I show how realism about causation is implicit therein. I present a genealogy of the concept of real causation Peirce embraces. I explicate Peirce's view of the scientific significance of realism about causation, and why he finds it compelling. Finally, I argue that Peirce would intervene in the current debate by saying that those committed to abductive theorizing and causal explanation are implicitly realist.

Towards noncommutative quantum reality

The implications of the physical theory of quantum mechanics on the question of realism is much a subject of sustaining interest, while the background questions among physicists on how to think about all the theoretical notion and ‘interpretation’ of the theory remains controversial. Through a careful analysis of the theoretical notions with the help of modern mathematical perspectives, we give here a picture of quantum mechanics, as the basic theory for ‘nonrelativistic’ particle dynamics, that can be seen as being as much about the physical reality as classical mechanics itself. The key is to fully embrace the noncommutativity of the theory and see it as a notion about the reality of physical quantities. Quantum reality is then just a noncommutative version of the classical reality.

Bubble Up: Are you ok? How to ask a real question and get a real answer.

Bubble Up: Are you ok? How to ask a real question and get a real answer.

The Digital Revolution: It’s Time to Take Control [From the Editor’s Desk

This past fall, after university students returned to the classroom, I had an opportunity to walk the campus of my alma mater. It was an enlightening experience for me, taking in the cool but sunny weather and the mosaic of colors from the autumn leaves. The experience brought back many fond memories. One thing had definitely changed though—the students. It was clear that many were focused elsewhere: looking down with thumbs racing across their device keyboards, glancing up only occasionally to be sure they didn’t run into a wall or perhaps another student. With almost every student on campus seemingly oblivious to their surroundings, I wondered if our coming generation of leaders would find a way for electronic media to somehow let go of them, or if the real question is are they able to let go of it? I too am admittedly guilty of occasionally pulling my phone out of my pocket, itching to see if there is a new text message or email. Being connected 24/7 has advantages, but it seems the United States has become a nation addicted to electronic media.

Effect of the mask on communication: A perspective of the scenario of covid-19

The COVID-19 pandemic has radically altered our way of life, and it has become the "new normal" for us. The wearing of a facemask in public areas has now become a requirement. Many people used to cover their faces in public places for a variety of reasons, but it was not considered proper etiquette at the time. In the past, wearing a mask was considered unsuitable in many situations due to concerns about safety and identification. This has changed. Even though the vaccine for COVID-19 has already begun, and COVID-19 may be eradicated within a few years, wearing a mask will continue to be a part of everyday life for a variety of reasons. A new pandemic is expected at any time as a result of pollution, and we have observed and scientifically shown that viral infections have decreased significantly since we began wearing masks in public places. Specifically, the problem of face-to-face communication while wearing a face mask will be investigated in this research. The movement of the muscles on the face is very significant in the process of communication since it conveys a lot of information. When we wear a mask, the lower sections of our faces, including the part of the nose, the corners of our mouths, the corners of our jaws, and the insides of our cheeks, are hidden. The movements of the muscles in these areas of the face are critical in the communication process because they convey significant information. It is necessary to speak the messages that would otherwise be delivered through facial expressions. The use of facial expressions to complement spoken communication has been phased out. The real question is how communicators will navigate their way out of this dilemma.

Identifying the Factors Affecting the Cost Management of Road Construction Projects in Tanzania: Review Paper

Among the key factors to take into consideration before the execution of any project is time, cost and quality. Most projects meet Quality and sometimes time but cost management is a real question in the implementation of many construction projects in the world. Poor management of the cost causes the delay of many road construction projects in the world too. In this paper literature review has been conducted to identify different factors that contribute to cost management both positive and negative ones. Different factors were identified that contributed to poor management of cost in highway construction projects such as force majeure factors like weather conditions, political matters and other factors like change in design, change of scope, conflict among the stakeholders, poor leadership, incompetence of project manager and subcontractors, in Tanzania from the literature perspective the challenge of cost overrun is very critical as insisted by different authors in their researches. Most of the projects deviate from their planned budget by even more than 50%. Apart from all causes of cost overrun, delay in these projects is the critical problem which causes the cost increase, the problem of delay is critical in both developing and developed countries, hence mitigating the factors discussed in this paper will minimize the problem of delays and cost overrun too although further research is required in this area to come up with proper mitigation measures to minimize the problem of cost overrun in road construction projects in Tanzania.

A modest proposal: Free will is real

ABSTRACT We present a hybrid philosophical/psychological argument in defense of ‘free will.’ The argument builds on the proposals in philosopher Christian List’sbook, Free will is real. We show that List’s psychological account of free will – that it requires the ability to consider alternatives, to make a choice, and to enact that choice – has already been proven, via research into goal functioning. Thus, the real question is: ‘can we use our free will wisely?’ Self-concordance research and implicit/explicit motive discrepancy research suggest that sometimes, we can’t. Ironically, the same fact that makes us free – that our choices are based on our imaginative capacities – also makes us free to be clueless, i.e., out of touch with ourselves or with reality. In building our argument we also discuss self-determination theory, the evolved symbolic self, system 1 versus system 2 functioning, and the hierarchical organization of human existence.

Unbinding Isaac: The Significance of the Akedah for Modern Jewish Thought

Unbinding Isaac: The Significance of the Akedah for Modern Jewish Thought

The Prospect of Pragmatic Confucian Democracy: Reply to Dryzek, Macedo, Ackerly, and Li

The Prospect of Pragmatic Confucian Democracy: Reply to Dryzek, Macedo, Ackerly, and Li

Abstract IA-008: The KPC model has helped advance pancreatic cancer therapy: Disagree

Abstract Pancreatic cancer researchers have grappled with the difficulty of reproducing the complex tumor microenvironment which holds the key to improving therapeutic treatments for the disease. For decades, murine models of the disease have underpinned all clinically-relevant pancreatic cancer research and indeed, the transgenic KPC mouse model has been touted as our closest in vivo model to human disease; reproducing disease progression from early PanIN lesions, extensive fibrosis, metastatic spread and chemoresistance. Numerous clinical studies have been initiated based on the work done in this model. However, most of these trials have failed to successfully improve outcomes for pancreatic cancer patients or to even progress beyond phase 2 clinical trials. A/Prof Phillips will argue that the KPC model, while a useful tool to understand pancreatic cancer biology in the laboratory, has had limited clinical impact due to key differences in mouse and human cell biology as well as inherent limitations of the model. Patient-derived 3D tumor models of pancreatic ductal adenocarcinoma (PDAC) have potential to overcome many limitations associated with the KPC model. Human PDAC organoid and whole-tissue explant cultures may hold the key to precision medicine in their ability to predict patient response to existing treatments, to guide translation of new therapies to the clinic in a technique which is both scalable and provides rapid readout 1,2. Furthermore, the ability of the human tumor explant model to retain the multicellular microenvironment of patient tumors provides a powerful tool to study the effects of tumor and stromal targeting agents for pancreatic cancer 3. Coupling this model with the recent explosion of spatial omics techniques also allows us to understand the tumor composition and therapeutic response of individual patient tumors down to the single cell level, negating the need for more homogenous mouse models that require extensive replication and yet make generalized predictions on therapeutic response. Thus, with the advent of these personalized “at-the-bench” 3D human models of pancreatic cancer, perhaps the real question is whether we still require the KPC mouse model?

The Next Era of Biomedical Research

The Next Era of Biomedical Research

Suresh Narayanan Comment on Wage Differentials in Malaysia: Public Employment, Gender, and Ethnicity

Suresh Narayanan Comment on Wage Differentials in Malaysia: Public Employment, Gender, and Ethnicity

Prediction of Mobile Model Price us ing Machine Learning Techniques

Mobile phone has become a common commodity and usually the most common purchased item. Thousands of types of mobiles are released every year with new features and new specification and new designs. So the real question is prediction is that what is the real price of the mobile and to estimate the price of the mobile within the market for optimal marketing and successful launch of the product. Price has become a major factor for development of any product and its sustainability in the market. Mobile prices also impact the marketing of the mobile and also its popularity with other competitors. With the available specifications and desired designs, money is also an important factor to survive within the market. Customer usually sees that they are able to buy with the specification with the given estimated price or not. So to estimating the price is an important factor before releasing the mobile and also to know about the market and competitors. In this Prediction, Dataset is collected from the existing market and different algorithms are applied to reduce the complexity and also identify the major selection features and get the best comparison within the data .This Tool is used to find the best price with maximum specifications.

Representation, Deflationism, and the Question of Realism

How can we distinguish between quasi-realist expressivism and normative realism? The most promising answer to this question is the “explanation” explanation proposed by Dreier (2004), Simpson (2018), and others: the two views might agree in their claims about truth and objectivity, or even in their attributions of semantic content to normative sentences, but they disagree about how to explain normative meaning. Realists explain meaning by invoking normative facts and properties, or representational relations between normative language and the world, the thought goes, while expressivists appeal instead to desire-like mental states in their explanations of meaning. However, I argue that, if we adopt a deflationary approach to representation and other related notions, there need be no such explanatory divide between expressivism and anything recognizable as a plausible notion of normative realism. Any alleged explanatory criterion for realism will either be incompatible with deflationism, or it will fail to capture some standard versions of normative realism. I conclude that, in a deflationary framework, expressivism is compatible with genuine realism.

Data‐drivensparse partial least squares

AbstractIn the supervised high dimensional settings with a large number of variables and a low number of individuals, variable selection allows a simpler interpretation and more reliable predictions. That subspace selection is often managed with supervised tools when the real question is motivated by variable prediction. We propose a partial least square (PLS) based method, called data‐driven sparse PLS (ddsPLS), allowing variable selection both in the covariate and the response parts using a single hyperparameter per component. The subspace estimation is also performed by tuning a number of underlying parameters. The ddsPLS method is compared with existing methods such as classical PLS and two well established sparse PLS methods through numerical simulations. The observed results are promising both in terms of variable selection and prediction performance. This methodology is based on new prediction quality descriptors associated with the classicaland, and uses bootstrap sampling to tune parameters and select an optimal regression model.

There is no “origin” to SARS-CoV-2

Since the beginning of the COVID-19 pandemic in 2020 caused by SARS-CoV-2, the question of the origin of this virus has been a highly debated issue. Debates have been, and are still, very disputed and often violent between the two main hypotheses: a natural origin through the “spillover” model or a laboratory-leak origin. Tenants of these two options are building arguments often based on the discrepancies of the other theory. The main problem is that it is the initial question of the origin itself which is biased. Charles Darwin demonstrated in 1859 that all species are appearing through a process of evolution, adaptation and selection. There is no determined origin to any animal or plant species, simply an evolutionary and selective process in which chance and environment play a key role. The very same is true for viruses. There is no determined origin to viruses, simply also an evolutionary and selective process in which chance and environment play a key role. However, in the case of viruses the process is slightly more complex because the “environment” is another living organism. Pandemic viruses already circulate in humans prior to the emergence of a disease. They are simply not capable of triggering an epidemic yet. They must evolve in-host, i.e. in-humans, for that. The evolutionary process which gave rise to SARS-CoV-2 is still ongoing with regular emergence of novel variants more adapted than the previous ones. The real relevant question is how these viruses can emerge as pandemic viruses and what the society can do to prevent the future emergence of pandemic viruses.