Queensland University Of Technology Research Articles

An advanced bioengineered 3D model mimicking prostate cancer-induced bone metastasis microenvironment

Event Abstract Back to Event An advanced bioengineered 3D model mimicking prostate cancer-induced bone metastasis microenvironment Ali Shokoohmand1, 2, Nathalie Bock1, 2, Judith A. Clements1, 2 and Dietmar W. Hutmacher1, 2, 3, 4 1 Queensland University of Technology (QUT), Institute of Health and Biomedical Innovation, Australia 2 QUT, Australian Prostate Cancer Research Centre – Queensland, Australia 3 Technical University of Munich (TUM), Institute for Advanced Study, Germany 4 Georgia Institute of Technology, George W Woodruff School of Mechanical Engineering, United States Introduction: The metastatic spread of cancer cells to distant sites of the body, in particular bone, is the major cause of death among prostate cancer patients[1]. Despite the current disease models, it has not yet been well understood how cancer cells attain the ability to survive and establish metastasis within the surrounding microenvironment, remaining one of the most challenging aspects in the treatment of metastatic cancers. Hence, to closely mimic the tumour microenvironment, this study aimed at developing a 3D bioengineered in vitro bone model for the study of bone metastasis. Martials and Methods: Medical-grade Polycaprolactone (PCL) from Purac was used to produce tubular scaffolds by melt electrospinning writing on a custom-built machine[2]. Scaffolds (1 cm length, 5 mm diameter, 100 µm thickness, 250 pore size, 0-90° pattern) were further coated by calcium phosphate (CaP) for osteogenic properties[3] and seeded with 4×105 human osteoprogenitor bone cells (hOBs), isolated from human bone samples[4]. After reaching 3D confluency, the tubular constructs were transferred from static cultures to the vessel of a bi-axial rotating bioreactor[5] and mineralisation was induced for 6 weeks with osteogenic media (50 μg/ml ascorbate-2-phosphate, 10 mM β-glycerophosphate, 100 nM dexamethasone)[6]. After 6 weeks, human mesenchymal stem cells (MSCs) from the same patient and human umbilical vein endothelial cells (HUVECs) were mixed (1:1 ratio; 6×105 cells per gel) with a gelatin methacrylamide-based gel (gelMA) and injected in the centre of the osteoblast-derived tubular scaffold, followed by cross-linking with 365 nm wavelength UV for 10 minutes[7] to form a soft gel, 3-4 kPa in stiffness, inside the tubular scaffold. After one week of culture in the rotating bioreactor, allowing for capillaries to form, 2×104 human prostate cancer cells (LNCaP, C4-2B, PC3) were injected into the central part of the construct and co-cultured for an additional two weeks, in order to mimic and study human prostate cancer metastasis to the bone (Figure 1). Results and Discussion: We have successfully grown human bone-derived osteoblast cells onto tubular PCL scaffolds with cells fully covering the scaffolds after six week post seeding. Furthermore, we have successfully grown cancer cells in gelMA where after 14 days cells are forming large spheroid-like colonies ranging from 100 to 200 µm, mimicking the tumour-like characteristics (Figure 2). We are currently optimizing the mechanical properties of gelMA for optimal growth of HUVECs and MSCs and capillary formation. Further studies involve micro-computed tomography, scanning electron microscopy (SEM) and immunohistochemistry for assessing the extent of bone metastatic lesions in the novel bioengineered model. Conclusion: This novel bioengineered 3D in vitro model better reflects the natural 3D environment of prostate cancer metastasis to the bone and hence will provide an ideal platform to study current and novel treatments against metastasis, ultimately improving patient outcomes.

Polymer topology and graft density affect in vitro mineralisation

Event Abstract Back to Event Polymer topology and graft density affect in vitro mineralisation Lisbeth Grondahl1, Norsyahidah Mohd Hidzir1, 2, Shuko Suzuki3 and Edeline Byrne4 1 The University of Queensland, School of Chemistry and Molecular Biosciences, Australia 2 Universiti Kebangsaan Malaysia, School of Applied Physics, Faculty of Science & Technology, Malaysia 3 Queensland Eye Institute, Australia 4 Queensland University of Technology, School of Chemistry, Physics and Mechanical Engineering, Australia Introduction: Many polymeric materials used as implant materials lack functional groups and are therefore considered bioinert. Introducing functional groups onto such otherwise inert polymers is one method that has been explored extensively [1]. In vitro mineralisation in simulated body fluid (SBF) can be used to evaluate a material’s ability to form a strong interface with bone tissue in vivo [2] and early studies demonstrated that such a correlation exists for grafted polyethylene [3]. Fundamental studies on self-assembled monolayers found that the mineralisation capacity in SBF depends on the type functional group (-PO42- > -COO- > -OH) [4]. However, a more complex picture emerges when evaluating the mineralisation capacity of graft copolymers. Our published work on phosphate-containing graft copolymers attached to expanded polytetrafluoroethylene (ePTFE) have illustrated that a linear polymer topology, high retention of phosphate groups and effective coverage of the material surface is required for inducing hydroxyapatite mineralisation [1]. This current study has investigated if similar effects exist for membranes grafted with carboxylate-containing monomers. Materials and Methods: ePTFE membranes obtained from Pall Corporation were grafted with of acrylic acid (AA) and itaconic acid (IA) [5]-[7]. These grafted materials were characterised by XPS to evaluate carboxylate group density and graft extent (~ surface coverage). Mineralisation was evaluated by immersing the membranes in SBF solution [2] for up to 3 weeks. Samples were examined using SEM/EDX to obtain the morphology and elemental composition of mineral formed. FTIR was used to elucidate the mineral phase formed. Results and Discussion: The untreated ePTFE membrane did not show any mineralisation after 3 weeks immersion in SBF which correlates with the substrate being highly hydrophobic and lacking functional groups. All substrates with carboxylate-containing graft copolymers induced mineralisation in SBF, however, the extent of mineralisation and the Ca/P ratio of the mineral formed varied. Samples with a low surface coverage resulted in mineral phases of a very high Ca/P ratio of 2.7 [1] while high surface coverage yielded a Ca/P ratio equivalent to Hydroxyapatite as illustrated in the figure. The carboxylate group density also affected mineralisation with high COO/F ratios in the substrate required to effectively induce mineralisation however, there was no benefit observed using AA-co-IA compared to AA graft copolymers. While all these grafted materials have grafted chains of linear topology, a parallel study on crosslinked PAA gels resulted in more acidic mineral phases (eg. Brushite or Monetite) based on EDX. Conclusion: This work illustrates that high graft density of carboxylate-containing polymers are also capable of promoting hydroxyapatite formation while low graft densities results in other mineral phases. Linear topology is again important for formation of the mineral phase Hydroxyapatite. N M Hidzir acknowledges the Universiti Kebangsaan Malaysia for a PhD scholarship; This work was carried out in part in the Centre for Microscopy and Microanalysis, The University of Queensland, the Queensland node of the Australian Microscopy and Microanalysis Research Facility (AMMRF)

Multiphasic constructs and cell sheet technology in the context of periodontal regeneration

Event Abstract Back to Event Multiphasic constructs and cell sheet technology in the context of periodontal regeneration Cedryck Vaquette1, Saso Ivanovski2 and Dietmar Werner Hutmacher1 1 Queensland University of Technology, Institute of Health and Biomedical Innovation, Australia 2 Griffith University, School of Dentistry and Oral Health, Menzies Health Institute Queensland, Australia Introduction: Periodontitis is a common chronic inflammatory disease that results in degradation of the supporting structures around teeth and in severe cases can lead to tooth loss. Current surgical treatments such as Guided Tissue Regeneration (GTR) are efficient at limiting the progression of the disease by controlling the inflammatory aspect of periodontitis but regeneration is not commonly achieved. Our groups have developed a tissue engineering strategy involving the utilisation of cell sheets combined with biphasic biomaterial scaffolds in order to enhance the regenerative capacity of GTR. The biphasic structures, composed of a bone and periodontal compartments, are specifically designed to recapitulate the highly organised and hierarchical architecture of the native periodontium composed of cementum, periodontal ligament, alveolar bone and gingival tissue. This paper provides an overview of the research we have performed in this area along with our latest advancements. Materials and Methods: Several generations of polycaprolactone (PCL) biphasic constructs were developed combining additive manufacturing methodologies such as Fused Deposition Modelling (FDM), solution electrospinning and Melt Electrospinning Writing (MEW). Our most recent research has resulted in the development of a fibre guiding scaffold manufactured by MEW for the bone compartment and by nanofabrication technologies for the creation aligned silk fibroin micro-channels for the periodontal compartment. Our constructs have been tested in vitro and in vivo into rodent and ovine models while testing several architectures and cell sources (gingival fibroblasts, periodontal ligament fibroblasts, and bone marrow mesenchymal stem cells). Results and Discussion: We have demonstrated that our biphasic scaffolds fulfilled the requirements for GTR; wound stabilisation, space maintenance and selective cell repopulation, and were capable of regenerating fraction or entire portion of the periodontium complex in a rodent ectopic model and in a surgically created periodontal one model. The presence of the cell sheets was also essential for the improved regeneration of the targeted organ. The incorporation of aligned channels into the biphasic scaffold design resulted in guiding the orientation of the newly formed periodontal ligament fibres. Conclusion: The development of multicompartment scaffolds for periodontal regeneration has been proven as an effective strategy when combined with cell delivery. Further to the delivery of cells, tissue guidance provided by topographical clues, is also essential and resulted in a physiologically relevant attachment of the newly formed periodontal fibres. Keywords: Regenerative Medicine, 3D scaffold, complex tissue orgnization, cell sheeting Conference: 10th World Biomaterials Congress, Montréal, Canada, 17 May - 22 May, 2016. Presentation Type: New Frontier Oral Topic: Combinatorial approaches to biomaterial design Citation: Vaquette C, Ivanovski S and Hutmacher D (2016). Multiphasic constructs and cell sheet technology in the context of periodontal regeneration. Front. Bioeng. Biotechnol. Conference Abstract: 10th World Biomaterials Congress. doi: 10.3389/conf.FBIOE.2016.01.00904 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 27 Mar 2016; Published Online: 30 Mar 2016. Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Cedryck Vaquette Saso Ivanovski Dietmar Werner Hutmacher Google Cedryck Vaquette Saso Ivanovski Dietmar Werner Hutmacher Google Scholar Cedryck Vaquette Saso Ivanovski Dietmar Werner Hutmacher PubMed Cedryck Vaquette Saso Ivanovski Dietmar Werner Hutmacher Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.

Biological response of human articular chondrocytes to shear loading following changes to hydrogel surface properties

Event Abstract Back to Event Biological response of human articular chondrocytes to shear loading following changes to hydrogel surface properties Christoph Meinert1, Karsten Schrobback1 and Travis Klein1 1 Queensland University of Technology, Institute of Health and Biomedical Innovation, Australia Introduction: Articular cartilage provides a nearly frictionless surface with remarkable capacity to bear and distribute loads in a synovial joint. Alterations to the articular surface may however lead to pathological loads and unbalanced metabolism, ultimately leading to the development of osteoarthritis. Here, we established a hydrogel-based cartilage model with tailorable friction coefficients and evaluated the response of human chondrocytes in these models to dynamic shear loading imparted through custom bioreactor components. Materials and Methods: Bilayered hydrogels, with a thin cell free layer and a 2 mm alginate methacrylate (ALMA) layer containing 10^7 human articular chondrocytes (3 donors, with ethical approval, Passage 2) per mL, were photocrosslinked in the presence of Irgacure 2959. The cell-free layer consisted of either ALMA or PEG diacrylate with either 40 or 80 mol % 4-styrene sulfonic acid (PEG-40S, PEG-80S), resulting in different charge densities, as verified by EPIC-uCT. Friction coefficients were assessed over a range of velocities using custom components on an Instron Microtester. Bulk compressive modulus, swelling ratio, and water content were also measured. Further, microscopic images taken during dynamic shear loading in a custom device were used to generate strain maps using digital image correlation. Constructs were cultured in chondrogenic medium for 21 days free-swelling, followed by 11 days with 0 or 1 mm shear loading (1 h/d, 1 Hz) using custom bioreactor components. Chondrocyte response was assessed by quantitative real-time polymerase chain reaction (qRT-PCR), and matrix accumulation was assessed by immunofluorescence and biochemical assays. Results and Discussion: Constructs were able to effectively model the frictional properties of healthy, damaged, and osteoarthritic cartilage, while other physical characteristics such as compressive moduli, mass swelling ratio, and water content were not affected (Figure 1). Dynamic shear stimulation of constructs with low surface friction significantly promoted chondrogenesis and extracellular matrix synthesis as assessed by gene expression, immunofluorescence, and biochemical analysis (Figure 2). In contrast, shear stimulation of constructs with high surface friction inhibited chondrogenesis to a great extent, but induced transcription of matrix metalloproteinases involved in the degradation of cartilage extracellular matrix in osteoarthritis. Shear strains during dynamic loading were higher in the high-friction constructs than low-friction constructs, which likely explains the differences in chondrocyte response. Conclusion: This study demonstrates that surface friction may act as a key regulator of chondrocyte homeostasis by governing the magnitude of shear deformation during dynamic loading. Australian Research Council; Peter Levett, Cameron Lutton, Robert Sah, Carly Sutton Keywords: Biomimetic, biomaterial, surface property, stimuli-response Conference: 10th World Biomaterials Congress, Montréal, Canada, 17 May - 22 May, 2016. Presentation Type: New Frontier Oral Topic: Biomimetic materials Citation: Meinert C, Schrobback K and Klein T (2016). Biological response of human articular chondrocytes to shear loading following changes to hydrogel surface properties. Front. Bioeng. Biotechnol. Conference Abstract: 10th World Biomaterials Congress. doi: 10.3389/conf.FBIOE.2016.01.00873 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 27 Mar 2016; Published Online: 30 Mar 2016. Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Christoph Meinert Karsten Schrobback Travis Klein Google Christoph Meinert Karsten Schrobback Travis Klein Google Scholar Christoph Meinert Karsten Schrobback Travis Klein PubMed Christoph Meinert Karsten Schrobback Travis Klein Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.

Generating Benefits and Negotiating Tensions through an International Doctoral Forum: A Sociological Analysis

Workshops and seminars are widely-used forms of doctoral training. However, research with a particular focus on these forms of doctoral training is sporadic in the literature. There is little, if any, such research concerning the international context and participants’ own voices. Mindful of these lacunae in the literature, we write the current paper as a group of participants in one of a series of doctoral forums co-organised annually by Beijing Normal University, China and Queensland University of Technology, Australia. The paper voices our own experiences of participation in the doctoral forum. Data were drawn from reflections, journals, and group discussions of all 12 student and academic participants. These qualitative data were organised and analysed through Bourdieu’s notions of capital and field. Findings indicate that the doctoral forum created enabling and challenging social fields where participants accrued and exchanged various forms of capital and negotiated transient and complex power relations. In this respect, the sociological framework used provides a distinctive theoretical tool to conceptualise and analyse the benefits and tensions of participation in the doctoral forum. Knowledge built and lessons learned through our paper will provide implications and recommendations for future planning of, and participation in, the doctoral forum series and similar activities elsewhere.

Massive Open Online Courses in Education of Robotics

Recently, the requirement for learning is constantly increasing. MOOC – massive open online courses represent educational revolution of the century. A MOOC is an online course accessible to unlimited number of participation and is an open access via the web. Mayor participants in the MOOCS are: Coursera, Udacity (Stanford, since 2012) and edX (Harvard, MIT, since 2012). In this paper two MOOCs are considered: Introduction for Robotics and Robotics Vision, both from the Queensland University of Technology, Brisbane, Australia.

Continuing my journey on designing and refining criterion-referenced assessment rubrics

I am delighted that my 2006 article was in the top 10 most downloaded articles on the 10 year anniversary of the Journal of Learning Design . In 2006, when the article was written, I worked at the Queensland University of Technology (QUT). At that time, the development of criterion-referenced assessment rubrics was gaining momentum. In 2015, as I write this reflection, all 37 Australian universities that support a law school universally accept criterion-referenced assessment as opposed to norm-referenced assessment. This year, I started working at the University of the Sunshine Coast and I am proud to say that its assessment policy explicitly endorses the development of criterion-referenced assessment rubrics. I have published several journal articles on designing and implementing criterion-referenced assessment rubrics and it continues to be my quintessential research interest.

Teachers' attitudes towards the gifted: The importance of professional development and school culture

No accessFULL TEXTAustralasian Journal of Gifted EducationOther Journal Article01 December 2015Teachers' attitudes towards the gifted: The importance of professional development and school culture Authors: Carly Lassig Authors: Carly Lassig Lecturer, Faculty of Education, Queensland University of Technology, email: [email protected] Google Scholar More articles by this author SectionsAboutView PDFExport CitationsAdd to FavouriteAdd to FavouriteCreate a New ListNameCancelCreate ToolsTrack CitationsCreate Clip ShareFacebookTwitterLinkedIn COPY LINK Abstract Given that teachers have one of the most significant influences on the educational development of gifted students, reports of negative attitudes and beliefs in popular myths about giftedness are cause for concern. It is important to understand teachers' attitudes and beliefs to implement effective training and educational practices to improve education for gifted students. This study explored the attitudes of Australian primary school teachers (N = 126) towards intellectually gifted children and their education at eight schools. These schools could be categorised into four different classifications in regards to their involvement in gifted education. Key findings include significant associations between teachers' attitudes and their school classifications (p < .001), and their participation in gifted and talented education inservice training (p < .001). Findings from this study suggest that further teacher training and school-wide involvement in gifted education may assist in improving attitudes towards intellectually gifted children and their education. Full Text DOI Previous article Next article RelatedDetails View PUBLICATION DETAILSDate of Publication:December 2015Volume:24Issue:2Journal:Australasian Journal of Gifted EducationISSN:1323-9686Page Range:6-16First Page:6Last Page:16Source:Australasian Journal of Gifted Education, Vol. 24, No. 2, Dec 2015: 6-16Date Last Modified:05 September 2019 12:02Date Last Revised:08 January 2019SubjectTeachers--AttitudesTeachers of gifted children--Training ofTeachers of gifted children--In-service trainingTeachers of gifted children--AttitudesTeachers of gifted childrenGifted children--Education METRICS Downloaded 85 times Copyright© Australian Association for the Education of the Gifted and Talented, 2015Download PDFLoading ...

Guest Editorial:World Indigenous Legal Conference 2014 – Special Forum

&lt;em&gt;The World Indigenous Legal Conference 2014 was hosted by the Indigenous Lawyers Association of Queensland, and held at Queensland University of Technology, Brisbane, from 24-27 June 2014. The conference brought together over 250 delegates from the academy, legal practice, and community and government organisations, representing a diverse range of Indigenous nations from Australia, Aotearoa, the Americas, Pacific Islands, Asia and Africa to discuss issues of importance to the survival of Indigenous peoples worldwide.&lt;/em&gt;

Thermal performance of load‐bearing walls made of cold‐formed hollow flange channel sections in fire

SummaryTypical load‐bearing light gauge steel frame (LSF) walls are made of conventional lipped channel section studs and gypsum plasterboards. Current research at the Queensland University of Technology is investigating the effects of using new thin‐walled stud sections on the fire‐resistant rating of LSF walls, in particular, the use of hollow flange channel (HFC) sections. A sound knowledge on the thermal performance of these LSF walls is essential, but expensive and time‐consuming nature of fire tests has acted as a barrier. In this study, finite element models were developed to predict the thermal performance of load‐bearing LSF walls made of HFC section studs exposed to fire on one side. The developed models were validated using the results of five full‐scale standard fire tests of LSF walls. They were then extended to perform a parametric study where the effects of stud dimensions, geometries, spacings and wall configuration were evaluated. The hot and cold flange time‐temperature profiles of HFC studs were developed as a function of the aforementioned parameters, which can be used to predict the fire resistance ratings of LSF walls. This paper presents the fire tests, and the details of the developed finite element models and the thermal performance results of LSF walls made of HFC studs. Copyright © 2015 John Wiley &amp; Sons, Ltd.

Technology Focus: Data Management and Communication (October 2015)

Technology Focus I would like to highlight three main trends that most exploration-and-production (E&amp;P) operators are facing across the globe—the value of reservoir-surveillance information, the slow pace of automation and instrumentation, and the way forward. The Value of Reservoir-Surveillance Information Global energy demand will grow more than 33% by 2035. Most of the supply will come from the oil industry, if we do our job right. As demand rises, the complexities also increase. The prime value of data captured through continuous surveillance is letting the reservoirs talk. Reservoirs talk through information and knowledge derived from data capture, analysis, and integration. This results in proper understanding and prognosis through applying better analytics and, thus, improving the decision-making process. In this way, we will be able to extend the lives of mature fields, discover new fields, improve refining and manufacturing efficiency, enable smart awareness, optimize corporate-scale operations, dynamically respond to supply and demand, integrate business and support functions across supply chain and geography, manage proactive growth, integrate information among all assets, and implement greater intelligence. Slow Pace of Automation and Instrumentation There is no question that smarter work flows enabled by digital automation increase profitability. To realize such opportunities, industry has been deploying hardware for sensing and actuation in the last 3 decades, in combination with data-driven modeling and remote collaboration. Many major oil fields around the world would not be producing today if not for opportune field automation. However, building such capability across the globe has not been solid enough. Ninety percent of worldwide mid- to large-size operators (i.e., 100,000 BOPD or more) have embraced oilfield automation in the simplest form; however, less than 1% of such equivalent production has a consistent application of data-to-knowledge transformation. The slow acceptance of the technology is because of the short-term gratification from profitable and low-risk operations, lack of knowledge of the added value from related technologies, and management blindness. What Is Next? Many business and digital corporations claim that between 100 billion and 200 billion devices could be connected by 2020. Young engineers may not understand why it is not possible to access any real-time well data from his mobile device, understand its past performance, and allow the simulation of multiple scenarios to see the impact of decisions. With close to a billion people connected at any moment playing online strategy games, how is it possible that our industry is still so far behind with respect to the gaming philosophy? JPT Recommended additional reading at OnePetro: www.onepetro.org. SPE 170680 Predicting Failures From Oilfield Sensor Data Using Time-Series Shapelets by Om Prasad Patri, University of Southern California, et al. SPE 171636 A Flowback-Guided Approach for Production-Data Analysis in Tight Reservoirs by O.D. Ezulike, University of Alberta, et al. SPE 170633 Data as an Asset: What the Upstream Oil and Gas Industry Can Learn About Big Data From Social Media by Robert K. Perrons, Queensland University of Technology, et al. SPE 173416 Addressing Oil and Gas Big-Data Challenges at the Remote Edge by Serhii Konovalov, et al. IPTC 17997 Intelligent-Field Real- Time Data Reliability Key Performance Indices by Abdulrahman A. Al-Amer, Saudi Aramco, et al.

Parallax in the park

This article describes a parallax experiment performed by undergraduate physics students at Queensland University of Technology. The experiment is analogous to the parallax method used in astronomy to measure distances to the local stars. The result of one of these experiments is presented in this paper. A target was photographed using a digital camera at five distances between 3 and 8 metres from two vantage points spaced 0.6 m apart. The parallax distances were compared with the actual distance measured using a tape measure and the average error was 0.5 ± 0.9%.

Pathophysiology team teaching: Bioscientist contribution to knowledge integration in a nursing subject

Journal of Clinical NursingVolume 24, Issue 23-24 p. 3739-3741 Research in Brief Pathophysiology team teaching: Bioscientist contribution to knowledge integration in a nursing subject Martin Christensen BSc, MSc, MA, PGCert, PhD, RGN, Corresponding Author Martin Christensen BSc, MSc, MA, PGCert, PhD, RGN School of Nursing, Faculty of Health, Queensland University of Technology, Caboolture, Qld, Australia Correspondence: Martin Christensen, Associate Professor, School of Nursing, Caboolture Campus, Tallon Street, Caboolture, Qld 4510, Australia. Telephone: +61 7 53167508 E-mail: [email protected]Search for more papers by this authorJudy A Craft BAppSci, PhD, Judy A Craft BAppSci, PhD orcid.org/0000-0003-3998-5591 School of Biomedical Sciences, Faculty of Health, Queensland University of Technology, Caboolture, Qld, AustraliaSearch for more papers by this authorLisa Wirihana PGCert Critical Care, BN, MN, RN, Lisa Wirihana PGCert Critical Care, BN, MN, RN School of Nursing, Faculty of Health, Queensland University of Technology, Caboolture, Qld, AustraliaSearch for more papers by this authorChristopher J Gordon MExSc, PhD, BN, RN, Christopher J Gordon MExSc, PhD, BN, RN Sydney Nursing School, University of Sydney, Sydney, NSW, AustraliaSearch for more papers by this author Martin Christensen BSc, MSc, MA, PGCert, PhD, RGN, Corresponding Author Martin Christensen BSc, MSc, MA, PGCert, PhD, RGN School of Nursing, Faculty of Health, Queensland University of Technology, Caboolture, Qld, Australia Correspondence: Martin Christensen, Associate Professor, School of Nursing, Caboolture Campus, Tallon Street, Caboolture, Qld 4510, Australia. Telephone: +61 7 53167508 E-mail: [email protected]Search for more papers by this authorJudy A Craft BAppSci, PhD, Judy A Craft BAppSci, PhD orcid.org/0000-0003-3998-5591 School of Biomedical Sciences, Faculty of Health, Queensland University of Technology, Caboolture, Qld, AustraliaSearch for more papers by this authorLisa Wirihana PGCert Critical Care, BN, MN, RN, Lisa Wirihana PGCert Critical Care, BN, MN, RN School of Nursing, Faculty of Health, Queensland University of Technology, Caboolture, Qld, AustraliaSearch for more papers by this authorChristopher J Gordon MExSc, PhD, BN, RN, Christopher J Gordon MExSc, PhD, BN, RN Sydney Nursing School, University of Sydney, Sydney, NSW, AustraliaSearch for more papers by this author First published: 03 September 2015 https://doi.org/10.1111/jocn.12959Citations: 17Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Citing Literature Volume24, Issue23-24December 2015Pages 3739-3741 RelatedInformation

The placental microbiome; microbial presence in nature’s transplant

The placental microbiome; microbial presence in nature’s transplant

2015 4thTERMIS World CongressBoston, MassachusettsSeptember 8–11, 2015

2015 4^thTERMIS World CongressBoston, MassachusettsSeptember 8–11, 2015

Field Evaluation of a Stormwater Treatment Train with Pit Baskets and Filter Media Cartridges in Southeast Queensland

Field monitoring of a stormwater treatment train has been underway between November 2013 and May 2015 at a townhouse development located at Ormiston, southeast Queensland. The research was undertaken to evaluate the effectiveness of a 200 micron mesh pit basket in a 900 square format and an 850 mm high media filtration cartridge system for removing total suspended solids and nutrients from stormwater runoff. The monitoring protocol was developed with Queensland University of Technology (QUT), reflecting the Auckland Regional Council Proprietary Device Evaluation Protocol (PDEP) and United States Urban Stormwater BMP Performance Monitoring Manual with some minor improvements reflecting local conditions. During the 18 month period, more than 30 rain events have occurred, of which nine comply with the protocol. The Efficiency Ratio (ER) observed for the treatment devices are 32% total suspended solids (TSS), 37% for total phosphorus (TP) and 38% total nitrogen (TN) for the pit basket, and an Efficiency Ratio of 87% TSS, 55% TP and 42% TN for the cartridge filter. The performance results on nine events have been observed to be significantly different statistically (p &lt; 0.05) for the filters but not the pit baskets. The research has also identified the significant influence of analytical variability on performance results, specifically when influent concentrations are near the limits of detection.

Curation on Campus: An Exhibition Curatorial Experiment for Creative Industries Students

Curation on Campus: An Exhibition Curatorial Experiment for Creative Industries Students

Audience response systems can facilitate communal course feedback

Background: At Queensland University of Technology (QUT), the Bachelor of Radiation Therapy course evaluation has previously suffered from low online survey participation rates. A communal instantaneous feedback event using an audience response system (ARS) was evaluated as a potential solution to this problem. The aims of the project were to determine the extent to which this feedback event could be facilitated by ARS technology and to evaluate the impact the technology made on student satisfaction and engagement. Methods: Students were invited to a timetabled session to provide feedback on individual study units and the course overall. They provided quantitative Likert-style responses to prompts for each unit and the course using an ARS as well as anonymous typed qualitative comments. Data collection was performed live so students were able to view collective class responses. This prompted further discussion and enabled a prospective action plan to be developed. To inform future ARS use, students were asked for their opinions on the feedback method. Results: Despite technological difficulties, student evaluation indicated that all responders enjoyed the session and the opportunity to view the combined responses. All students felt that useful feedback was generated and that this method should be used in the future. The student attendance and response rates were high, and it was clear that the session had led to the development of some insightful qualitative feedback comments. Conclusions: An ARS contributed well to the collection of course feedback in a communal and interactive environment. Students found it enjoyable to use, and it helped to stimulate useful qualitative comments.

Education for sustainability in construction management curricula

In response to the call for sustainability education in construction courses, higher education institutions have started to incorporate sustainability components into their construction courses to some extent. This research aims to investigate sustainability embedded in construction management (CM) courses using the Queensland University of Technology as a case study. A content analysis of its CM course structure, unit aims, learning objectives and lecture materials is conducted to examine the sustainability elements incorporated into the CM curriculum. The results show that the course incorporates sustainability components into the existing course structure mainly through horizontal integration, embedding sustainability into general units rather than as an add-on subject. Additionally, the sustainability topics embedded in the course cover a comparatively broad and balanced range of sustainability categories, i.e. background knowledge, policies and regulations, environmental issues, social issues and economic issues as well as technology and innovation, although social sustainability aspects need to be further strengthened. This research addresses the need for urgency in the development of an effective sustainability education framework for construction courses. It is expected that the findings from this study will facilitate the improvement of sustainability education in construction courses generally.

The past, present, and future (?) of crime-related forensic accounting methodology

Purpose – The purpose of this paper is to explore the origins of crime-related forensic accounting methodology in the USA. Design/methodology/approach – The author describes how these early methods have evolved through the use of technology. Findings – The author also discusses the next generation of crime-related forensic accounting tools and techniques which, although in limited use today, will grow to widespread use in the near future. Originality/value – This viewpoint is a summary of a presentation made at the 3rd National Forensic Accounting Teaching and Research Symposium held at the Queensland University of Technology on February 10, 2014.