In this paper, we investigate the existence and uniqueness of weak solutions for a new class of initial/boundary-value parabolic problems with nonlinear perturbation term in weighted Sobolev space. By building up the compact imbedding in weighted Sobolev space and extending Galerkin’s method to a new class of nonlinear problems, we drive out that there exists at least one weak solution of the nonlinear equations in the interval [0,T] for the fixed time T>0.