We develop an approximation scheme for the quantum mechanics of N D0-branes at finite temperature in the 't Hooft large-N limit. The entropy of the quantum mechanics calculated using this approximation agrees well with the Bekenstein-Hawking entropy of a ten-dimensional non-extremal black hole with 0-brane charge. This result is in accord with the duality conjectured by Itzhaki, Maldacena, Sonnenschein and Yankielowicz. Our approximation scheme provides a model for the density matrix which describes a black hole in the strongly-coupled quantum mechanics.
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