Spinning is the process of combining and twisting a string of fibers to create a yarn. Vortex spun yarn is one of the advanced development for the high quality and production speeds in the spinning sections. This study aims to analyze and compare the properties of vortex spun yarns of different fibers based on the nozzle position. Here, polyester, viscose, modal, and blended of cotton and polyester fibers were used to prepare the vortex spun yarn. The nozzle positions were also changed during the production of vortex spun yarn. The different yarn properties like mass variation, imperfection, hairiness, tensile strength, and elongation were measured to evaluate the performance of yarn qualities. It was observed that the yarn performance of different fibers was also depended on the nozzle position. The results indicated that using the shorter distance between the front roller and the spindle, the vortex spun yarn performances were increased. As a result, analyzing many relevant parameters and nozzle position depending on the vortex spun properties establishes a clear strategy for the industrial manufacture of spinning that is more environmentally friendly.