Parental Quality Of Life Research Articles

Relationships between resilience and quality of life in parents of children with cancer.

NCT03631485.

New Parents Experienced Lower Parenting Self-Efficacy during the COVID-19 Pandemic Lockdown.

Background: The COVID-19 pandemic is a global issue which affects the entire population’s mental health. This study evaluates how restrictions to curtail this pandemic change parenting self-efficacy, depressive symptoms, couple satisfaction and health-related quality of life in parents after delivery of a newborn. Methods: In this prospective single center evaluation of parental self-efficacy and quality of life, four validated questionnaires were used to repeatedly assess parenting self-efficacy (Tool to measure Parental Self-Efficacy, TOPSE), depressive symptoms (Edinburgh Postnatal Depression Scale, EPDS), couple satisfaction (Couple Satisfaction Index, CSI) and health-related quality of life (short form 12, SF12). Fifty-three parents of 50 infants answered a total number of 63 questionnaires during the lockdown period to limit the spread of COVID-19. These questionnaires were matched with 63 questionnaires of 58 other parents that had answered them before or after strong pandemic related measures. Results: Parents experienced lower parenting self-efficacy during the strict pandemic measures as compared to before and after (p = 0.04). In terms of age, socioeconomic, marital status and duration of hospitalization we detected no significant difference between both groups. On univariate linear regression, TOPSE scores were associated with gestational age (p = 0.044, parameter estimate: 1.67, 95% CI: 0.048 to 3.301), birth weight (p = 0.035, parameter estimate: 0.008, 95% CI: 0.001 to 0.015), number of newborns’ siblings (p = 0.0554, parameter estimate: 7.49, 95% CI: −0.174 to 15.145) and distance of home from hospital (p = 0.043, parameter estimate: −0.38, 95% CI: −0.745 to −0.011). Interestingly, there was a positive correlation between quality of life and TOPSE scores, suggesting that those who experience a higher self-efficacy also have a higher quality of life. Conclusions: When implementing a lock-down period psychological effects such as lower experience of parental self-efficacy have to be considered.

Usefulness of Gastrojejunostomy Prior to Fundoplication in Severe Gastro-Esophageal Reflux Complicating Long-Gap Esophageal Atresia Repair: A Preliminary Study

Background: Gastro-esophageal reflux disease (GERD), requiring surgical correction, and nutritional problems are reported after long-gap esophageal atresia (LGEA) repair and might jeopardize the postoperative course in some babies. We report an exploratory evaluation of the role of transgastric jejunostomy (TGJ) as a temporary nutritional tool before surgery for GERD in LGEA. Methods: Seven infant patients operated on for LGEA with intra-thoracic gastro-esophageal junction (GEJ) and growth failure, requiring improvement in their nutritional profile in anticipation of surgery, were retrospectively evaluated. Post-surgical follow-up, including growth evolution, complications, and parental quality of life (QoL), were considered. Results: The TGJ was placed at a mean age of 8.6 ± 5.6 months. The procedure was uneventful and well-tolerated in all seven cases. At 6.6 ± 2.0 months after TGJ placement, significant weight gain (weight z-score −2.68 ± 0.8 vs −0.9 ± 0.2, p < 0.001) was recorded, allowing the GERD surgery to proceed. A significant difference in hospital admissions between 3 months before and post-TGJ insertion was noted (4.8 ± 0.75 vs. 1.6 ± 0.52, p < 0.01). A significant amelioration of QoL after TGJ placement was also recorded; in particular, the biggest improvements were related to parents’ perceptions of the general health and emotional state of their babies (p < 0.001). Conclusions: The placement of TGJ as a temporary nutritional tool in selected cases of LGEA could improve nutritional conditions and parental QoL before fundoplication, allowing successful surgical treatment of GERD to be carried out.

Supplemental Material for Health-Related Quality of Life in Parents and Partners of People With type 1 diabetes: Development and Validation of Type 1 Diabetes and Life (T1DAL) Measures

Supplemental Material for Health-Related Quality of Life in Parents and Partners of People With type 1 diabetes: Development and Validation of Type 1 Diabetes and Life (T1DAL) Measures

Quality of life of families with celiac disease children in Eastern Province of Saudi Arabia

Objectives: The prevalence of Celiac Disease (CD) is increasing worldwide, and the kingdom of Saudi Arabia reports the highest seroprevalence rate. A strict Gluten-Free Diet (GFD) for lifetime is the only therapy to CD patients. It has been demonstrated that childhood CD negatively affects the health of parents. On the other hand, the emotional and social wellbeing of the parents has a great impact on the Quality Of Life (QOL) of CD children. However, limited literatures are available on the QOL of parents of CD children. This study aims to evaluate the QOL of families of celiac disease children on GFD treatment and identify modifiable risk factors for poor QOL. Methods: A total of 73 children with celiac disease living in different cities of the eastern province of the kingdom of Saudi Arabia were included in this descriptive, cross-sectional study. A modified version of the celiac disease-specific instrument measuring the QOL was used. Data analyses were done using descriptive statistics, correlation coefficient test and the Fisher’s exact test. Results: The mean QOL score was found to be 65.8 and the median was 64.0. Very few (5.48%) parents perceived their QOL to be good, while majority of them (78.08%) considered it as moderate; and the remaining parents (16.44%) regarded it as poor. Conclusions: We found that small-sized families, with young and educated mothers have a better QOL than others. Most of the emotional and psychosocial elements of QOL were related to the difficulties in availability of GFD in daily life.

Quality Of Life And Coping In Parents Raising Children With Duchenne Muscular Dystrophy (DMD) In Nepal

Introduction: Quality of Life (QoL) and Coping are important components of mental health, especially important to parents raising children with Duchenne Muscular Dystrophy (DMD). Children with DMD face difficulties due to their disability and create special challenges for parents.&#x0D; Material And Method: The study aimed to assess QoL, demographic variables and coping strategies of parents raising children with DMD in Nepal. A descriptive cross-sectional design was adopted to collect data from 32 parents (mothers = 15, 47%; fathers =17, 53%) through purposive sampling. Socio-demographic pro-forma, World Health Organization's Quality of Life Questionnaire-BREF (WHOQOL-BREF) and Brief COPE Inventory were assessed.&#x0D; Results: The results revealed parents scores were below cutoff &lt;60, indicating probable poor quality of life. QOL was moderately positively correlated with coping strategies and highly positively correlated with emotion-focused coping. There were significant differences in psychological health of parents in reference to their occupation, and in reference to their hospital born children. Parents in government job had better psychological health and parents into private business significantly used emotion-focused coping. Mutual caregivers had significantly better psychological health. Parents without health related problems significantly adopted problem focused coping and emotion focused coping.&#x0D; Conclusion: These findings will help stakeholders to understand DMD children and their impact on QOL and coping of parents and will facilitate to develop appropriate psychosocial intervention programs for the parents for the effective management of their children and their psycho-social wellbeing.

Validation of a Hearing-Related Quality-of-Life Questionnaire for Parents and Deaf or Hard-of-Hearing Infants and Toddlers.

To design and validate a hearing-related quality-of-life questionnaire targeted toward parents and deaf or hard-of-hearing infants and toddlers: the Hearing-Related Infant/Toddler and Parent Quality of Life (HIP-QL) questionnaire. Cross-sectional questionnaire and prospective instrument validation. Academic pediatric otolaryngology clinic. A 67-question questionnaire developed from constructs of a grounded theory analysis was administered to parents of 31 deaf or hard-of-hearing children and 14 typically hearing children. Questionnaire construct validity, reliability, and discriminant validity were tested. Based on exploratory factor analysis, a 32-item construct composed of developmentally appropriate questions was reduced to a 17-item construct with 4 domains addressing quality of life for both child (auditory/communication behavior, temperament) and parent (management, parent-directed factors). Internal consistency measures were appropriate (Cronbach's alpha = 0.65), and test-retest reliability was high (intraclass correlation coefficient = 0.73). Total HIP-QL scores correlated significantly with related total PedsQL scores (r = 0.57, P < .001). As predicted, parents of children who are deaf or hard of hearing reported significantly lower mean HIP-QL scores but not mean PedsQL scores. HIP-QL was more sensitive than PedsQL for predicting case versus control membership (86.7% vs 76.9%). Multivariable regression confirmed a negative relationship between severity of hearing loss and HIP-QL score after controlling for age, sex, income, and maternal education. This context-specific questionnaire is the first validated quality-of-life instrument for parents and deaf or hard-of-hearing infants and toddlers. Previously, parental stress and functional disability questionnaires were used as proxies; therefore, this questionnaire has the potential to serve as an important tool for patient- and caregiver-centered outcomes research.

Phenotyping peripheral neuropathic pain in male and female adolescents: pain descriptors, somatosensory profiles, conditioned pain modulation, and child-parent reported disability.

Neuropathic pain (NeuP) can be difficult to diagnose and manage in children. Data regarding prevalence and sex-dependent differences are limited, and more detailed phenotyping is needed. This observational cohort study recruited adolescents (10-17 years) with NeuP or complex regional pain syndrome (CRPS). After pain history and NeuP questionnaires, quantitative sensory testing was performed. Individual z-score plots were calculated with body-region control measures and matched to mechanism-related sensory profiles (sensory loss, thermal hyperalgesia, and mechanical hyperalgesia). Conditioned pain modulation was assessed with pressure pain threshold and a contralateral cold conditioning stimulus, and meaningful conditioned pain modulation defined as twice the standard error of measurement. Patients and parents completed validated questionnaires for child quality of life (QoL), pain catastrophizing, and self-reported anxiety/depression. Males (n = 23) and females (n = 43) with NeuP (n = 52) or CRPS (n = 14) reported moderate-severe pain with neuropathic sensory descriptors. Mixed patterns of sensory gain/loss at pain sites were not sex-dependent. Thermal hyperalgesia was common in both NeuP and CRPS, whereas sensory loss occurred only with NeuP and in a smaller proportion than adult cohorts. Conditioned pain modulation was inhibitory in 54%, facilitatory in 14%, and nonresponders had variable cold conditioning sensitivity. Males and females reported marked impairment of QoL, increased emotional distress, and pain catastrophising. Child-parent QoL scores correlated, but catastrophizing scores were discordant when parents or adolescents reported higher anxiety/depression. NeuP in adolescents is associated with significant pain, physical impairment, and psychosocial impairment. Quantifying alterations in somatosensory profiles, descending modulation, child and parent psychological function will inform individualized therapy and stratification for future clinical trials.

Physiotherapy: At what cost? Parents experience of performing chest physiotherapy for infants with cystic fibrosis.

Physiotherapy is one of the most burdensome aspects of cystic fibrosis (CF) care. Healthcare requirements for older children with CF are reported to impact parental quality of life and physiotherapy adherence. How parents of infants experience performing chest physiotherapy as a part of CF care is unknown. This study aimed to explore the experience of performing chest physiotherapy for parents of infants with CF. In this study, 13 parents of infants (aged 1-2years) with CF participated in one in-depth semi-structured interview and completed a daily diary for five days. Principles of hermeneutic phenomenology guided interpretation of interview transcripts, diary entries, and field notes. For these parents, being responsible for performing chest physiotherapy was an ever-present experience of pressure, doubt, and guilt. Managing chest physiotherapy resulted in sacrifices that were perceived by parents as an expected and necessary part of meeting the healthcare needs of their child. Despite perceived sacrifices, performing chest physiotherapy was also experienced by parents as an opportunity to positively impact the health of their child. Awareness of parental perceptions and experiences of chest physiotherapy in CF may enhance the personalization of physiotherapy and minimize burden.

Predictors of Quality of Life among Parents of Children with Chronic Diseases: A Cross-Sectional Study.

Quality of life (QOL) is a key aspect of the health care process for children with chronic diseases and their families. Although clinical evidence regarding the impact of chronic disease on children exists, few studies have evaluated the effects of the interaction between sociodemographic and psychosocial factors on the family caregiver’s QOL, indicating a significant gap in the research literature. The present study aimed to identify the predictors of the QOL of parents of children with chronic diseases. Three parental sociodemographic predictors (age, schooling, and family income) and four psychosocial predictors (family functioning, social support, depression, and resilience) were examined. In this cross-sectional study, 416 parents of children with chronic diseases who were hospitalized at a National Institute of Health in Mexico City were interviewed. The participants completed a sociodemographic variables questionnaire (Q-SV) designed for research on family caregivers of children with chronic disease. The predicted variable was assessed through the World Health Organization Quality of Life Questionnaire. The four psychosocial predictors were assessed through the Family Functioning Scale, Social Support Networks Scale, Beck Depression Inventory, and Measurement Scale of Resilience. The regression model explained 42% of the variance in parents’ QOL. The predictors with positive weights included age, schooling, monthly family income, family functioning, social support networks, and parental resilience. The predictors with negative weights included depression. These findings suggest that strong social relationships, a positive family environment, family cohesion, personal resilience, low levels of depression, and a family income twice the minimum wage are variables associated with better parental QOL.

Experiences and Needs of Parents Caring for Children with Cerebral Palsy: A Systematic Review.

Caregiver burden of parents of children with disabilities is negatively associated with parental quality of life and psychosocial well-being and has been identified as a public health concern. Reviews have consolidated the experiences of these parents, but little is understood about the unique challenges faced by parents of children with cerebral palsy (CP). We aim to conduct an in-depth synthesis of the experiences and needs of parents of children with CP to better support them. Six electronic databases were searched systematically for qualitative research, and a thematic synthesis was performed. Seventeen studies from 1988 to 2019 encapsulating the experiences of 226 parents were included in this review. Four themes and 11 subthemes were identified: (1) self: the caregiver-parent trajectory (coming to terms with the fact, physical and emotional demands, and a nice outlet), (2) family: maintaining the family unit (juggling multiple children and parenting as a co-occupation), (3) society: social repercussions (facing public discrimination, rejection by extended family, and loss of freedom), and (4) parents' wish list (open communication and caring attitudes, funding and health care accessibility, social integration, and inclusivity). Apart from emotional adaptation and physical childcare difficulty, parents indicated a need for more information on health care services, funding, better attitudes and empathy from health care providers, properly trained educators, disability-friendly fixtures, and more public awareness. The findings in this review provide insight into the true experiences and needs of parents caring for children with CP and will aid clinicians in the development of family-centered care pathways for these patients.

Telemedicine and adherence monitoring in children with asthma.

Telemedicine, defined as synchronous video visits between a provider and a child with asthma, often takes place in the school setting. This review examines the new electronic sensors for adherence monitoring and studies that used telemedicine in the school setting to improve asthma outcomes. School-based telemedicine provides an important service to families of school-aged children who have difficulty due to time and distance in planning and keeping in-person appointments with primary or specialty providers. Significant improvements in objective measures of asthma control are inconsistently observed although caregiver and parent quality of life and child self-management behaviors are improved and satisfaction is high. Assessment and outcomes related to adherence are mentioned in studies but results are not often reported. However, it appears that adherence interventions are beneficial while maintained but the effects are not sustained upon intervention discontinuation. The school setting provides a convenient and suitable environment to conduct telemedicine visits between school-aged children and their primary care or specialty provider. Electronic adherence sensors allow review of controller and rescue medication use through a cloud-based dashboard and provides an opportunity for real-time assessment and intervention by providers to improve asthma outcomes.

Parent and Family Functioning in Pediatric Inflammatory Bowel Disease.

Although the impact of pediatric inflammatory bowel disease (IBD) extends beyond the patient to their parents and families, the focus of previous literature has largely been on investigating the patient’s medical and psychosocial functioning, with less consideration of the family system. Having a comprehensive understanding of parent and family functioning within the context of pediatric IBD is important given the role parents and family members have in the successful management of the disease and caring of the child. The current review paper aggregates the empirical research regarding parent and family functioning, including comparisons to normative samples, other illness groups, and how functioning relates to child psychosocial and health outcomes. Extant literature on parents and families in pediatric IBD has largely focused on the variables of parenting stress, parent psychosocial functioning, parent quality of life, and family functioning. Summary findings elucidate the complex relationships between parents, families, and children affected by IBD and highlight the importance of assessing parent and family functioning within pediatric IBD. The current review also offers implications for clinical practice, notes the limitations of the present literature, and provides recommendations for future research.

Prince sultan military medical city Riyadh, Saudi Arabia quality of life for parents having children with atopic dermatitis in Riyadh 2020 cross-sectional survey

Background: Atopic dermatitis is the most common chronic inflammatory skin disease in children. Therefore, it has an impact on patients’ quality of life (QoL). Families with children having AD are vulnerable to have diversity of physical as well as psychological difficulties, including experiencing extreme fatigue, stress, frustration, and low QoL, particularly when there is slow or no improvement in the condition.Aims/Objectives: We aimed to assess the quality of life (QOL) of parents having children with AD and to determine its predictors. Methods: This was an observational, cross-sectional survey study among families with children suffering from AD. Data was collected by the validated Arabic version of the dermatitis family impact (DFI) questionnaire [19]. The study has been conducted after taking the institutional review board approval at PSMMC. Due to the COVID-19 pandemic, data was collected online by sending an invitation to the parents explaining the aims and objectives of the research through WhatsApp, SMS messages, and social media.Results: A total of 93 parents having a child with atopic dermatitis (only one parent per family) participated in the current study, with a mean (±SD) age of 29.49 (±5.02). The vast majority (97.8%) of the respondents reported that mothers are the ones who take care of the AD child. The mean age of the children was 4.85 (±2.71). The overall mean (±SD) score of the DFI was 16.97(±7.55). The highest impact of having a child with atopic dermatitis was on the expenditures with a mean (±SD) score of 1.91 (±0.84) out of 3. On the other hand, the lowest effect was on the family leisure activities, with a mean score of 1.55 (±0.83). The level of effect of atopic dermatitis on the quality of life of parents having children with atopic dermatitis is severe in 23.66%, moderate in 43.01% of the respondents, and low in 27.96%. The DFI total score differed significantly only by participants' age and marital status.Conclusion: Atopic dermatitis (AD) had a moderate impact on the QOL of parents whose children had AD. Marital status and both parents and child age were the factors that significantly correlated with the parents' QoL.

Migration of adult children and quality of life of older parents left-behind in Nepal.

Studies regarding the impact of adult children's migration on older parents left-behind have focused on physical and mental health. This study assessed the relationship between migration of adult children and quality of life (QOL) of older parents left-behind in Nepal. A cross-sectional community-based survey was carried out (May-July 2019) among 791 randomly selected older adults aged ≥60 years. QOL was measured using the World Health Organization Quality of Life-abbreviated scale, and migration status was assessed into three categories: no migration, internal migration only and any international migration. A range of sociodemographic characteristics were measured for adjustment. Associations between migration of children and each domain of the QOL were examined by multilevel mixed regression. Scores for QOL were; 58.8 ± 19.8 for physical, 63.7 ± 18.0 for psychological, 60.7 ± 16.2 for social, and 61.8 ± 15.0 for environmental domains. This study identified positive and null associations between the migration of children and QOL for parents, with higher scores for physical (b = 5.16, P = 0.017) and environmental (b = 3.19, P = 0.046) domains among left-behind parents whose children migrated internally compared with parents whose children did not migrate. The findings differ from previous research showing poorer QOL among left-behind older parents. Migration plays a significant role in shaping physical and environmental QOL among left-behind parents living in rural areas with important implications for migrants, their families, researchers and social scientists. Geriatr Gerontol Int 2020; 20: 1061-1066..

Quality of life in at—risk school-aged children with asthma

Introduction Asthma is the most common chronic condition of childhood. Urban, minority children from families of lower socioeconomic status have disproportionately higher rates of asthma and worse outcomes. We investigated the association between the presence of asthma and asthma severity among American, urban, minority children and reported quality of life (QOL) of children and their families. Methods We performed a prospective, cross-sectional study comparing QOL of urban, minority elementary school-age children with and without asthma. A convenience sample of children was enrolled from the pediatric emergency department (ED) and a specialized asthma clinic, at a large urban children’s hospital. We measured child and parent QOL using the Pediatric Quality of Life Inventory Version 4 (PEDSQL4), and evaluated associations with asthma, parental educational attainment, and frequency of ED visits. Results We enrolled 66 children, 76% were African American, and 61% were female. Overall child QOL was higher for those without asthma (p = 0.017, d = 0.59). Children with asthma also visited the ED almost twice as frequently (t [64] = −3.505, p < 0.001, d = 0.8), and parents of children with asthma reported a lower overall QOL (p = 0.04, d = 0.53) than those without asthma. Among children with asthma, a higher overall child QOL was associated with decreased asthma severity, more ED visits, and higher parental educational attainment. Conclusions Urban, minority elementary school-age children with asthma report a lower QOL than those children without asthma, and decreased asthma severity was associated with higher QOL.

Grandparental and overall social support as resilience factors in coping with parental conflict among children of divorce

Abstract The quality of life (QoL) evaluations of children of divorced parents have been little studied. The literature focuses on the consequences of divorce for their wellbeing as reported by adults or examined using tools designed from the adult perspective. This study examines how risk (parental conflict) and resilience factors (perceived overall social support, closeness to grandparents, and open discourse with them about divorce) are related to the self-reported QoL of children of divorce. Cross-sectional online questionnaires for a child and one parent were completed by 122 children aged 7–17, from 86 Israeli families. Hierarchical linear models were employed, with mixed models accounting for the interdependency of children's data within each family. All risk and resilience factors were examined from the children's perspective, except parental conflict that was examined also from the parent’s perspective. Parental conflict was found to be negatively associated and overall social support and close relationship with grandparents were positively associated with children's QoL evaluations. The more the children were involved in parental conflict, the more QoL measures were associated with it. The study also supported three models in which perceived overall social support and perceived grandparental support moderated the association between parental conflict and QoL evaluations. The importance of examining the wellbeing of children of divorce from their own perspective is discussed. In terms of practical implications, the findings suggest the need to reduce the involvement of children of divorce in parental conflict and to strengthen their social support systems, particularly their relations with grandparents.

Quality of life in parents of seriously Ill/injured children: a prospective longitudinal study.

Parents of children with serious childhood illness or injury (SCII) are at risk of experiencing poor quality of life (QoL). This study investigated the nature of parent QoL at the time of child diagnosis and seven months post-diagnosis, the change in parent QoL over time, and early factors influencing short-term and longer-term parent QoL. The sample was drawn from a prospective longitudinal cohort study conducted within a paediatric hospital setting. Participants comprised 223 parents of 167 children diagnosed with a life-threatening illness and hospitalised in the cardiology, oncology, or intensive care departments. Examined data included QoL ratings completed by parents within four weeks of diagnosis and seven months post-diagnosis, and demographic, illness-related, and psychosocial predictor measures collected within four weeks of diagnosis, or four months post-diagnosis. Generalised Estimating Equations were utilised to analyse data. Results indicated poor parent QoL at diagnosis, and normalised parent QoL at seven months. Improvement occurred most noticeably in the psychosocial domain. Reduced acute stress symptomatology and increased psychological flexibility were associated with higher parent QoL at diagnosis. Increased perceived emotional resources predicted enhanced parent QoL at seven months. Paediatric medical care teams should consider the challenges to QoL experienced by parents of children with SCII. Parents reporting acute stress symptoms during the acute-illness phase should be prioritised for intervention. Further, parent-dyads presenting at post-acute care settings reporting poor emotional resources would benefit from psychosocial and educative support.

Assessment of the relationships between optimistic life orientation and hope levels and health-related quality of life in parents

Objective: Approaching life with optimism and hope will increase one’s psychological well-being and quality of life. The aim of this paper was to evaluate the association between optimism and hope levels in adults on health-related quality of life in physical and mental areas. Methods: This cross-sectional study was conducted at three different primary schools in Eskisehir with a sample of 674 parents of students. In order to collect data, a questionnaire consisting of 4 parts was formed after conducting a comprehensive literature review. The first part includes the sociodemographic characteristics of the parents, the second part of the health-related quality of life scale “Short Form 12 (SF-12)’’, the third part of the Life Orientation Test (LOT) and the fourth part ‘’Dispositional Hope Scale’’ questions. Mann-Whitney U, Kruskal-Wallis and multiple linear regression analyzes were used to evaluate the data. Results: The ages of participants ranged from 24 to 55 years, with a mean ± SD of 36.23 ± 4.49 years.The scores from the health-related quality of life Physical Component Summary (PCS) Score ranged from 25.0 to 63.2 with a median of 50.5, while the scores from the Mental Component Summary (MCS) Score ranged from 15.6 to 66.3 with a median of 49.5. When both scales were taken together into a regression model, the influence of the LOT on physical health disappeared, and the effect of the Dispositional Hope Scale continued. Conclusion: Optimism and hope are closely related to one’s state of health. In generally healthy groups, optimism and hope will reflect the tendency to stay away from negative emotions and cognitions in order to protect one’s health. It was concluded that in order to improve one’s quality of life and health, it is important to make optimism and hopefulness a part of life.

Assessment of quality of life in parents of epileptic children and its associated factors

Background: Aim of the study was to assess quality of life (QOL) of parents of epileptic child and its association with various factors like demographic, clinical, therapeutic and behavioral factors.Methods: Consenting parents of 160 epileptic children were enrolled after finishing child’s visit to the pediatrician. Parents were enquired on baseline demographic variables like age, gender, socio-economic status, parental education; clinical details like type of epilepsy, duration of seizure, seizure frequency and co-morbidity and therapeutic factors like treatment of epilepsy and adverse drug reactions. QOL was evaluated using QOLCE questionnaire and Childhood Illness-related Parenting Stress Inventory and analysed.Results: Out of 160 parents, 85% belong to 30-40 years of age and 62.5% were male. Deteriorated quality of life was reported by parents as mean score 63.46±7.69. QOL was significantly poor (p&lt;0.05) in parents of younger child (&lt;6 yrs), education status (upto primary school only), employment status of parent (unemployed) and lower socioeconomic status. Assessment of disease related parameters revealed that type of seizure, seizure frequency, duration and co-morbidity were factors significantly affecting quality of life of parents with lower QOL scores(p&lt;0.05). QOL of parents of child with epilepsy undergoing polytherapy with multiple AEDs treatment, particle seizure control and having adverse drug reaction were associated with poor scores of health and well being (p&lt;0.05). It was found that parents of epileptic child had deteriorated QOL score with respect to behaviour patterns irrespective to conditions of epilepsy due to constant stress and anxiety and poor state of mind.Conclusions: QOL of parents was compromised in Indian children with epilepsy. Demographic factors like age of child, parental education, socio-economic status and clinical factors like type of seizure, frequency &amp; duration of seizure and co-morbid conditions significantly affect the QOL of parents. Significantly poor QOL scores was also due to therapeutic factors like treatment with polytherapy and adverse drug reactions with poor behavioral patterns which was observed in parents that should be taken care and should not be overlooked.