Quality Of Life In Adolescents Research Articles

A text messaging intervention and quality of life in adolescents with solid organ transplants.

Facilitating communication between adolescents and HCP outside of appointments may enhance patient experience and outcomes. The purpose of this study was to determine whether SMS enhances the healthcare experience, QoL, and medication adherence in adolescent SOT patients. This was a prospective observational study of an SMS platform (WelTel Inc) for SOT patients aged 12-19years. QoL was assessed before and after using the PedsQL™ Transplant Module. Medication adherence was assessed with the frequency of therapeutic tacrolimus levels and variation based on control chart analysis. Patient experience and engagement was evaluated with surveys, response rate to messages, and number of clinical conversations (>2 messages). Twenty-three patients were included (median age 15.7years (IQR 13.6-17.1)). Median intervention duration was 13.5months (range 4.0-16.7months). There was a 68% response rate (742/1095) with 375 clinical conversations. The majority of patients reported the intervention provided a positive outlook on their health (17/23), was useful (18/23), and improved their connection to HCPs (17/23). Following the intervention, there was no significant difference in the median scaled QoL scores (pre-intervention: 81 (IQR 76.5-93.3), post-intervention: 78 (IQR 76-93); p=.37), mean percentage of therapeutic tacrolimus levels (pre-intervention: 52±25%, post-intervention: 65±17%; p=.07), or variation on control chart analysis of tacrolimus levels. The WelTel messaging platform provided supplemental clinical care for a group of adolescent SOT patients that enhanced their healthcare experience. Patient QoL and adherence were unchanged following the intervention and remained at a high level.

Fontan Geometry and Hemodynamics Are Associated With Quality of Life in Adolescents and Young Adults

BackgroundDespite favorable short-term outcomes, Fontan palliation is associated with comorbidities and diminished quality of life (QOL) in the years after completion. We hypothesized that poor Fontan hemodynamics and ventricular function are associated with worse QOL. MethodsThis was a single-center study of Fontan survivors aged more than 12 years. Subjects completed a cardiac magnetic resonance scan and QOL questionnaire. Cardiac magnetic resonance-derived variables included Fontan geometry, and hemodynamics. Computational fluid dynamics simulations quantified power loss, pressure drop, and total cavopulmonary connection resistance across the Fontan. Quality of life was assessed by completion of the Pediatric Quality of Life Inventory. Longitudinal and cross-sectional comparisons were made between cardiac magnetic resonance and computational fluid dynamics parameters with patient-reported QOL. ResultsWe studied 77 Fontan patients, median age 19.7 years (interquartile range, 17.1 to 23.6), median time from Fontan completion 16 years (interquartile range, 13 to 20). Longitudinal data were available for 48 patients; median time between cardiac magnetic resonance and QOL was 8.1 years (interquartile range, 7 to 9.4). Median patient-reported Pediatric Quality of Life Inventory total score was 80 (interquartile range, 67.4 to 88). Greater power loss and smaller left pulmonary artery diameter at baseline were associated with worse QOL at follow-up. Greater pressure drop was associated with worse QOL at the same time point. ConclusionsFor Fontan survivors, measures of computational fluid dynamics hemodynamics and geometry are associated with worse QOL. Interventional strategies targeted at optimizing the Fontan may improve QOL.

A Multicenter Assessment of Food Allergy Quality of Life in Adolescents and Caregivers in Relation to Anxiety and Depression during the COVID-19 Pandemic

A Multicenter Assessment of Food Allergy Quality of Life in Adolescents and Caregivers in Relation to Anxiety and Depression during the COVID-19 Pandemic

A School-Based Approach to Building Resilience and Mental Health Among Adolescents on the Autism Spectrum: A Longitudinal Mixed Methods Study

Tackling mental health difficulties in adolescents on the autism spectrum requires a comprehensive prevention approach. A 3-year multisite proof-of-concept longitudinal study implemented an evidence-based multilevel resilience intervention in schools to promote protective factors at the adolescent, parent, and school level. The intervention, consisting of the adolescent, parent and teacher components of the Resourceful Adolescent Program–Autism Spectrum Disorder (RAP-ASD) augmented with the Index for Inclusion, was implemented in 6 secondary schools with 30 adolescents with an autism diagnosis in Grades 7 and 8, 31 parents of 23 of the adolescents, and school staff. The intervention was implemented with good validity and acceptability. Quantitative data from adolescents and parents were analysed using the Reliable Change Index, and qualitative data were analysed using Consensual Qualitative Research. Triangulated quantitative and qualitative outcomes from the majority of adolescents and their parents showed some evidence for promoting resilience for adolescents with a diagnosis or traits of autism, as reflected in reliable improvements in coping self-efficacy and school connectedness, and a reduction in anxiety symptoms and emotional and behavioural difficulties. A reliable improvement in depressive symptoms was more modest and was only achieved by a small minority of adolescents. This multilevel, strength-focused, resilience-building approach represents a promising and sustainable school-based primary prevention program to improve the quality of life for adolescents on the spectrum by promoting their mental health and providing their families with much needed support.

The impact of adherence and therapy regimens on quality of life in patients with congenital adrenal hyperplasia.

ObjectiveVarying outcomes regarding the quality of life (QoL) have been reported in patients with congenital adrenal hyperplasia (CAH). To assess the impact of adherence rate to medical therapy regimens on QoL in patients with CAH.PatientsAdolescents and adults aged 15–72 years with CAH due to 21‐hydroxylase deficiency at Karolinska University Hospital, Stockholm, Sweden.MeasurementsQoL was assessed using the Addison QoL (n = 72) and RAND 36 questionnaires (n = 75). Adherence to therapy regimens was measured using the Adherence Starts with Knowledge questionnaire (ASK‐12). Associations between QoL, type of glucocorticoid therapy prescribed and ASK‐12 results were examined. Results were compared to reference RAND 36 data obtained from a representative sample from the general Swedish population.ResultsA good adherence rate to therapy regimens and a younger age were key factors for a better QoL in study participants with CAH. Younger patients on hydrocortisone and with good adherence had higher RAND 36 scores than older patients on prednisolone independently adherence. Participants with classic CAH (both the salt‐wasting and simple virilizing form) reported higher QoL than those with nonclassic CAH. Patients with CAH, especially nonclassic, more frequently reported an impaired QoL than the general population, especially regarding limitations related to body pain, vitality and mental health.ConclusionA poor adherence rate to therapy regimens, rather than type of glucocorticoid was associated with impaired QoL in adolescents and adults with CAH.

Need for transition medicine in pediatric surgery - health related quality of life in adolescents and young adults with congenital malformations.

Survival rates of patients with visceral congenital malformations have increased considerably. However, long-term morbidity in these patients is high. In the last decades, these circumstances have led to a shift in goals of caretakers and researchers with a new focus on patients’ perspectives and long-term morbidity. Health-related quality of life (HrQoL) is the most commonly used patient-reported outcome measure to assess the impact of chronic symptoms on patients’ everyday lives. Most pediatric surgical conditions can cause a significantly decreased HrQoL in affected patients compared to the healthy population. In order to guarantee life-long care and to minimize the impact on HrQoL a regular interdisciplinary follow-up is obligatory. The period of transition from child-centered to adult-oriented medicine represents a critical phase in the long-term care of these complex patients. This scoping review aims to summarize relevant pediatric surgical conditions focusing on long-term-morbidity and HrQoL assessment in order to demonstrate the necessity for a well-structured and standardized transition for pediatric surgical patients.

Direct relations between sense of coherence and oral health-related quality of life in adolescents.

To verify the relations between sense of coherence (SOC) and dental caries on oral health-related quality of life (OHRQoL) of adolescents. A cross-sectional sample of 768 adolescents nested in a cohort study was evaluated. SOC was measured using Antonovsky's scale. Dental caries was collected considering the decayed, missing, and filled teeth index (DMFT). OHRQoL was collected through the Child Perception Questionnaire. Demographic, socioeconomic, and use of service variables were also collected. The mediation effects between variables were tested by structural equation modeling. The average age of the individuals was 17.5years. Individuals with high SOC scores had a positive impact on OHRQoL (β-coefficient=-0.573, p<0.00). Individuals with high DMFT (β-coefficient=0.080, p=0.034) and dental pain (β-coefficient=0.079, p=0.039) negatively impacted OHRQoL. Still, adolescents who had dental pain (β-coefficient=0.112, p=0.005), mothers with lower education levels (β-coefficient=-0.114, p=0.004), lower household income (β-coefficient=-0.131, p=0.003), and those who visited the dentist (β-coefficient=0.109, p=0.005) exhibited a higher DMFT index. SOC and dental caries had a direct effect on OHRQoL, indicating that oral conditions and psychosocial characteristics are important contributors to OHRQoL.

Designing and validation of a family-centered emotion regulation program and determining its effect Impulsivity and Family Quality of Life in adolescents with Oppositional Defiant Disorder

Background and Aim: The concern in the area of adolescent mental health and its impact on psychological and behavioral development and functions simultaneously with the increase in the prevalence of mental disorders, particularly oppositional defiant disorder, has increased significantly in adolescents in recent years. The purpose of this study was to designing and validation of a family-centered emotion regulation program and determining its effect on impulsivity and family quality of life in adolescents with Oppositional Defiant Disorder. Methods: The quasi-experimental research design was pretest-posttest and follow-up with the control group. The statistical population of this study included all adolescents 14-18 years old with oppositional defiant disorder in Tehran in 2021-2022. The sample size consisted of 32 Subjects of adolescents (16 in the experimental group and 16 in the control group) from the statistical population were selected by the available sampling method and placed in two groups of control and experimental. For the experimental group, a designed family-centered emotion regulation program was implemented, while the control group did not receive any training. The research instruments included the Adolescent Behavioral Problems Scale (Achenbakh, 1991), Impulsivity Scale (Barrat et al, 2004), and Beach Center Family Quality of Life Scale. Results: The results showed that family-centered emotion regulation intervention had a significant effect on impulsivity and family quality of life in the post-test and follow-up stages (P&lt;0.001). Conclusion: Findings of this study provide useful information about family-centered emotion regulation program and counselors and psychologists can use this intervention to improve impulsivity and family quality of life in adolescents with oppositional defiant disorder

What's missing in sex chromosome aneuploidies? Representation and inclusion

What's missing in sex chromosome aneuploidies? Representation and inclusion

Predictors of Quality of Life in Adults and Adolescents with Acne: A Cross-Sectional Study.

Acne is becoming more prevalent in adults, particularly women across the globe. Although previous studies have compared clinical and epidemiologic characteristics of adolescent and adult acne, an adequate understanding of the quality of life (QoL) of adult acne patients and associated comorbidities are still lacking. We sought to compare the differences between adolescent and adult patient groups, regarding gender, socio-clinico-demographic factors, and comorbid associations, as well as their relatedness with life quality. This is a cross-sectional study with 1013 acne patients. Data on the severity, onset and location of acne, sex, family history of acne, smoking and alcohol habits, medication history, presence of seborrhea, and other comorbidities were collected. We employed the classification used by the American Academy of Dermatology for assessing acne severity. To assess the QoL in the patients, the Dermatology Life Quality Index (DLQI) score was used. Of the 1013 patients included in this study; 380 (female: 333, male: 47) were adult, and 633 (female: 535 and male: 98) were adolescent cases. The median total DLQI scores of adult and adolescent groups were not significantly different. Our results showed that factors such as age, gender, duration, body mass index, family history, and psychiatric disorders exhibited no impact on QoL in both adolescents and adults. Age of onset was correlated with DLQI scores in the adult group. The main influencers of DLQI in the adult group were allergic disorders, hormonal imbalances, and previous treatment history. Besides, major influencers in adolescent patients were acne severity, acne location, hirsutism, hyperseborrhea, premenstrual exacerbation, menstrual irregularities, previous treatment history, and smoking. The findings of our current study have shown that DLQI has been influenced by different factors in adolescents and adults that should be kept in mind.

Determination of the Relationship Between Hypoglycaemia Fear and Quality of Life in Adolescents Monitored with the Diagnosis of Diabetes

Determination of the Relationship Between Hypoglycaemia Fear and Quality of Life in Adolescents Monitored with the Diagnosis of Diabetes

Sense of coherence and quality of life in adolescents with heart disease.

Objective:The aim of this study was to assess the association between the Sense of Coherence (SoC) and Quality of Life (QoL) in adolescents with heart disease.Methods:A cross-sectional study was carried out with 164 adolescents with congenital or valvular heart disease, aged between 10 and 18 years, treated in a referral center in the city of Recife – Brazil. The information collected contains census data, type of heart disease, economic status identified according to the Brazilian Criteria for Economic Classification (ABEP), as well as an evaluation of the SoC and the QoL.Results:The SoC (50.09) and QoL (72.23) exhibited high average scores. The SoC was positively correlated with all dimensions of the QoL scale (p<0.001). The social and school dimensions, respectively, presented the highest and lowest scores. The linear regression analysis revealed that the SoC influenced the school and emotional dimensions.Conclusions:This study demonstrates that the SoC is a protective factor in the life of adolescents. This factor helps on the improvement of perception of QoL and on successfully dealing with daily adversities and chronic stress.

Quality of Life in Adolescents and Young Adults with a Chronic Medical Condition: The Role of Perceived Maturity and Transition Readiness

Quality of Life in Adolescents and Young Adults with a Chronic Medical Condition: The Role of Perceived Maturity and Transition Readiness

Quality of life in adolescents who underwent congenital diaphragmatic hernia surgical repair.

The advances made in the surgical and postnatal treatment of congenital diaphragmatic hernia (CDH) have considerably improved patient survival, but morbidity remains significant. The objective of this study was to analyze the effect these sequels have on the health-related quality of life (HRQL) of adolescents and young adults who have survived CDH, and to compare it with that of the general population. A transversal descriptive study of patients diagnosed with CDH in our institution from 1997 to 2004 was carried out. Survival, location, hernia size, herniated organs, need for extracorporeal membrane oxygenation, and mechanical ventilation time were analyzed. In addition, a comparative study of the current HRQL of survivors was conducted using the SF-36 survey (36-Item Health Survey Short Form), which assessed physical function, physical role, body pain, general health, vitality, social function, emotional role, and mental health. Data of 24 healthy adolescents was used as a control group. Of the 29 survivors (70.7%), 21 were successfully contacted, and 16 responded to the survey. They all claimed their overall quality of life was good or very good. The group of adolescents who underwent CDH surgical repair had better results in the vitality (p= 0.001) and mental health (p<0.05) areas, but the overall HRQL score and the remaining health areas were similar. No significant differences were found regarding diaphragmatic size or need for ECMO. According to adolescent survivors who underwent CDH surgical repair, their quality of life is similar to that of other individuals of their age. Our results are encouraging and may prove useful for future parents of CDH patients.

Parents' perceptions of quality of life of their children and adolescents with type 1 diabetes during Ramadan fasting in Riyadh.

This study aimed to assess parents' perceptions of the quality of life (QoL) of their children with type 1 diabetes (T1D) during Ramadan fasting (RF). In this cross-sectional study, an Arabic-translated version of the standard diabetes-specific QoL questionnaire (PedsQL™ version 3.0) was used to compare perceptions of QoL during Ramadan month (Rm) versus non-Rm (NRm) of parents of children/adolescents with T1D from two tertiary hospitals in Riyadh. We used regression analysis to compare proxies (parents' reports) of their perceptions on their children/adolescents' QoL during Rm compared to NRm. A sample of 61 proxies (parents') of two age groups T1D offspring: 8-12 years (41%) and 13-18 years (59%) who reported their perceptions of their children/adolescents QoL during Rm were matched by children/adolescents' age and gender of 61 proxies in NRm. QoL scores of all domains were significantly lower in Rm compared to NRm; p < 0.0001, however, worries domain showed no statistical differences p = 0.052 in a regression analysis. The total aggregate median (IQR) in Rm was 850 (612-1,062) compared to 1,750 (1,475-2,062) in NRm, p < 0.001. The highest differences in NRm and Rm median scores were observed in communications (OR = 3.64; 95% CI 2.7-5.57) and treatment adherence (OR = 3.09; 95% CI 2.48-3.84) domains especially in the age of 13-18 years. Parents of adolescent boys, who are usually risk-takers and more exposed to outdoor activities, perceived lower QoL for them. Parents of adolescents with T1D perceived a lower QoL for their children during RF, especially in the treatment adherence and communication domains.

Quality Of Life in Children With Home Mechanical Ventilation - A Scoping Review.

IntroductionHome mechanical ventilation is an established method to support children suffering from chronic respiratory insufficiency, still more research is needed regarding mechanically ventilated children's and adolescents’ quality of life (QoL). Therefore, the aim of this scoping review was to explore research regarding QoL and lived experience of children and adolescents with home mechanical ventilation.MethodsA scoping review with systematic searches for research studies published between year 2000–2020 was performed in Cinahl, Medline, and PubMed. Studies that met the inclusion criteria were quality assessed and a thematic analysis was performed.ResultsIn total, ten articles were quality assessed and included in the results. Four themes emerged: Children's self-reported QoL, Parents’ perception and parent-proxy report, Differences between the child's and parent's perception, and challenges in daily life. Children with home mechanical ventilation reported a lower QoL than healthy children and children with other chronic diseases. Generally, parents rate their child's QoL lower than the children themselves.ConclusionThis is the first literature review focusing on HMV in the paediatric population. It is clear that HMV does not only affect the treated child or adolescent but also the whole family. It is important to regularly measure and evaluate QoL in children and adolescents with HMV to provide person-centered care. More research is needed to improve these children's and adolescents’ QoL.

The association between pubertal timing and quality of life among children and adolescents: a cross-sectional study in Chongqing, China.

To determine the relationship between pubertal timing and quality of life (QOL) in children and adolescents and to provide a basis for QOL intervention in pubertal children in the future to promote good adaptation and healthy physical and mental development of children. The survey was conducted in one county using a stratified cluster sampling method. The five physiological change items of the Puberty Development Scale (PDS) were used to assess the timing of puberty in students. Compared to students of the same age and the same sex, students who scored higher than the mean + standard deviation (SD) of individual developmental scores were defined as an early pubertal timing group. A 39-item QOL Scale for Children in Puberty was used to assess the QOL of the respondents. Multiple linear regression models were fitted separately for boys and girls. Of the 7223 students, 3754 (51.97%) were boys and 3469 (48.03%) were girls. The prevalence of early pubertal periods was 16.07%. The total QOL score in the early pubertal timing group (137.16 ± 18.67) was significantly lower than in the normal (on time) group (142.02 ± 17.98) and the late group (142.76 ± 18.35) (F = 37.311, P < 0.001). A multiple linear regression model showed that early pubertal timing was a risk factor for QOL (P < 0.0014), compared with normal and late pubertal timing. The early pubertal timing was associated with poorer QOL in children and adolescents. More attention should be paid to children with early pubertal timing in intervening children's QOL during pubertal development. Future longitudinal studies are needed to confirm the association between pubertal timing and QOL.

Participation in activity and quality of life in adolescents with Down Syndrome

Amaç: Bu çalışmanın amacı, Down Sendromlu adölesanların aktivitelere katılımlarının yaşam kalitesiyle birlikte değerlendirilmesi ve normal gelişimli adölesanlarla karşılaştırılmasıdır. Yöntem: Çalışmaya 30 adölesan dahil edildi. Bunlardan Down Sendromlu olan 15 olgu çalışma grubuna, normal gelişimli olan 15 olgu ise kontrol grubuna alındı. Aktivitelere katılımı değerlendirmek için Çocuk ve Ergen Katılım Ölçeği, yaşam kalitesini değerlendirmek için Çocuklar için Yaşam Kalitesi Ölçeği (13-18 yaş) ve kaba motor fonksiyonları değerlendirmek için Kaba Motor Fonksiyon Ölçeği-88 kullanıldı. Bulgular: Kontrol grubundaki adölesanların kaba motor fonksiyonları, çalışma grubundaki adölesanlara kıyasla daha gelişmiş durumdaydı (p&amp;lt;0,05). Kontrol grubundaki adölesanların yaşam kalitesi fiziksel ve psikososyal yönden çalışma grubundaki olgulardan daha yüksekti (p&amp;lt;0,05). Çalışma grubundaki adölesanların toplumsal ve sosyal yaşama katılımları kontrol grubundaki adölesanlardan daha yüksekti (p&amp;lt;0,05). Kontrol grubundaki adölesanların ise ev içi katılımı daha yüksekti (p&amp;lt;0,05). Sonuç: Down sendromlu adölesanların aktivitelere katılımı ve yaşam kalitesi, genel olarak normal gelişimli adölesanlara kıyasla daha düşüktür.

Kualitas Hidup Remaja di Kotamobagu Sulawesi Utara pada Masa Pandemi Coronavirus Disease 2019

Introduction: Quality of life is a measure to see an individual's health status comprehensively. Quality of life is assessed based on physical, psychological, social and environmental domains. Adolescents are one of the population that must be considered. The purpose of this study was to analyze the quality of life of adolescents in Kotamobagu, North Sulawesi during the Corona Virus Disease 2019 (Covid-19) pandemic. Method: This is a quantitative research. This research was conducted in Kotamobagu in October-November 2021. The respondents in this study were 441 teenagers who were junior high and high school students. The factors analyzed are the general quality of life of adolescents and the quality of life based on the dimensions of physical, psychological, social and environmental health. The data obtained were analyzed univariately. Results: The results of this study indicate that the quality of life of adolescents in Kotamobagu is more than 80% in the moderate and poor categories. The results of this study also showed that the average score of the quality of life for adolescents was 56.95. When viewed based on 4 dimensions of quality of life according to WHOQoL, namely physical, psychological, social and environmental health. The average score for the physical health dimension is 50.12, the psychological dimension is 60.89, the social relationship dimension is 51.32 and the environmental dimension is 64.89. Conclusion: That can be conclude that the quality of life of adolescents in Kotamobagu is still problematic, especially in the dimensions of physical health and social relations.

Factors associated with self-management independence and quality of life for adolescents and young adults with spina bifida engaged in a guideline-based transition clinic.

To determine characteristics associated with self-management independence and quality of life (QOL) among adolescents and young adults with spina bifida (AYASB) engaged in a spina bifida (SB) health care transition clinic. During SB transition visits, Eighty-eight AYASB ages 14-20 completed the Adolescent/Young Adult Self-management and Independence Scale II Self-Report/SB (AMIS II-SR/SB), scores ranging from 1-7 with 7 indicating full independence in activities, and the QUAlity of Life Assessment in Spina bifida for Teens (QUALAS-T), which has two subscales, family/independence (QFI) and bowel/bladder (QBB), with scores ranging from 0-100 with 100 indicating maximal QOL score. Demographic and clinical variables were collected from the electronic medical record. The baseline AMIS II-SR/SB score was 3.3 (SD 1.0). Baseline scores for QUALAS-T QFI and QBB subscales were 73.8 (SD 19.9) and 63.8 (SD 25.8). Older age was associated with a higher baseline AMIS II-SR/SB score (p = 0.017). Over time, AMIS II-SR/SB total significantly improved (p < 0.001), but QFI and QBB did not. AYASB not on chronic intermittent catheterization (CIC) and those using urethral CIC significantly improved in AMIS II-SR/SB total scores (p = 0.001), but those using abdominal channel CIC did not. Baseline bladder management method was associated with self-management improvement for AYASB engaged in a SB-specific transition clinic.