Quality Of Life In Hemodialysis Research Articles

Comparing the effects of active and passive intradialytic pedaling exercises on dialysis efficacy, electrolytes, hemoglobin, hematocrit, blood pressure and health-related quality of life.

The effect of exercise during hemodialysis has been a controversial issue, however, there are just few studies about the effect of active exercise during hemodialysis. This study aimed to compare the effects of passive and active intradialytic pedaling exercises on dialysis efficacy, electrolytes, hemoglobin, hematocrit, blood pressure and health-related quality of life in hemodialysis patients. This quasi-experimental study was conducted on 16 hemodialysis patients in Akhavan hemodialysis center in Kashan from April to November 2013. Active or passive intradialytic pedaling exercise was performed using a Mini-Bike for 30 minutes during the first two hours of the dialysis sessions. The quality of life (QOL) was assessed before and after the intervention. Blood pressure was examined at the beginning and then hourly during the dialysis sessions. Dialysis efficacy, levels of phosphorus, calcium, sodium, potassium and Blood urea nitrogen (BUN) were measured at the end of the intervention. Kolmogorov-Smirnov test, paired t test, Wilcoxon signed rank and Friedman tests and repeated measure analysis of variancewere used to analyze the data. No significant changes were observed in serum potassium, phosphorus and calcium levels at the end of the passive exercise program compared to the baseline. However, phosphorus levels were significantly decreased in the active exercise program (P < 0.05). Moreover, the mean diastolic blood pressure was significantly decreased after the passive exercise (P = 0.039). Passive exercise did not significantly change the dialysis efficacy, urea reduction rate, hemoglobin and calcium levels. The mean overall QOL was 63.78 ± 21.15 at the beginning of the study, which was increased to 77.07 ± 21.14 at the end of eight weeks of the intradialytic exercise (P = 0.007). The passive intradialytic exercise had a positive effect on blood pressure. The active exercise could decrease the serum phosphorus and potassium levels. Moreover, both exercise programs could significantly improve the QOL. Both active and passive intradialytic exercises can have some beneficial effects.

QUALITY OF LIFE IN HEMODIALYSIS PATIENTS.

Purpose:To explore the quality of life in hemodialysis patients.Material and Methods:The sample studied consisted of 320 patients undergoing hemodialysis in one-day dialysis center. Data were collected by the completion of a specially designed questionnaire which apart from the sociodemographic and clinical variables, it also included the scale Missoula-VITAS Quality of Life Index (MVQOLI) for assessing quality of life.Results:Of the 320 hemodialysis patients, 57,2% were men while 28,1% of the participants were 71-80 years old. The average total score of quality of life was found to be 17.43 (in a range 0-30). The total score of quality of life was found to be higher in participants <60 years (p= 0,009), of higher educational level (p=0.001), being very informed about the health problem (p=0,013), complied with therapeutic recommendations and the proposed diet (p=0,025 & p=0,012, respectively), having very good relations with the medical and nursing staff or other patients (p<0,001), not experiencing difficulties with social or family environment (p=0,001), had help at home (p <0,001) and in those who did not conceal their health problem from the social environment (p<0.001). Furthermore, it was found that the increasing duration of hemodialysis session entailed poorer quality of life (p<0,001). These results were largely confirmed by multiple linear regression.Conclusions:Sociodemographic and clinical characteristics seems to influence the quality of life in hemodialysis patients.

Increasing depression, anxiety and quality of life in hemodialysis

Increasing depression, anxiety and quality of life in hemodialysis

Religious wellbeing as a predictor for quality of life in Iranian hemodialysis patients.

Aim:Spiritual well-being is known as a main resource for adjustment and coping when confronted with stressful situations such as managing a chronic disease. The aim of this study is to determine the very relationship between spiritual well-being and quality of life in hemodialysis patients.Methods:A convenience sample of 95 patients with end-stage renal disease who were referred to main hemodialysis centers were included from December 2012 to June 2013. Data was collected by using a socio-demographic questionnaire, the SF-36 quality of life scale, and the spiritual wellbeing scale. Descriptive analysis, Pearson’s correlation and logistic regression analysis were performed for statistical assessment.Results:The mean age of the patients evaluated was 50.4 (SD=15.72) years of age, and 61.1% of the patients were male. Both religious and existential domains of spiritual wellbeing were associated with bodily pain, vitality, social functioning and mental health (P<0.05). The results of multiple logistic regression showed that religious well-being was associated with better quality of life in both domains of physical (OR=1.17; p=0.01) and mental (OR=1.14; p=0.02) components after controlling for socio-demographic and clinical variables.Conclusion:Religious well-being should be considered important predictive factors for the better quality of life in hemodialysis patients. This indicates the need for psychosocial and spiritual supports in the care of these patients.

Comparison of depression between kidney transplant recipients from live donors with cadavers in hospitals of Mashhad University of Medical Sciences

Abstract Background & aim: Kidney transplant surgery may impact various aspects of the life and results in individual and psychological problems. Receiving a kidney from a cadaver donor is associated with beliefs related to death of donor and with recipient’s survival. The aim of this study was to compare the rate of depression in patients receiving kidney from living donors with cadaveric donor kidney transplant ,patients that were referred to nephrology clinics in hospitals of Mashhad University of Medical Sciences in 2010. Materials & methods: A descriptive – comparative design was used. The sample of the study consisted of 60 patients receiving kidney from living donors and 60 cadaveric kidney transplantation attended to nephrology clinics in hospitals of Mashhad University of Medical Sciences. Data were collected by a demographic questionnaire and Beck depression Inventory. The reliability of this test was evaluated with test-retest and Pearson correlation test was 0. 95. Data were analyzed with SPSS software (version 13). Finding: Depression scores in living kidney transplantation group were 11. 6±5. 7 , and in the cadaveric group was 16. 4±9. 4. Independent t-test showed a significant difference between two groups scores of depression (P . [January 24, 2010] Pascazio L et al, (2010) Anxiety, depression and emotional profile in renal transplant recipients and healthy subjects: A comparative study. Transplantation Proceedings. 42(9) 3586-3590 Pawar A et al «Cognitive and emotional effects of renal transplantation»,1 January 2006, [on line] . [3 Apr 2010]. Perez S-G et al (2008) Influence of the psychological state of relatives on the quality of life ofpatients at 1 year after transplantation. Transplantation Proceeding. 40(9)3109-11. Rezaei R et al (2009)[ Comparison of body image in hemodialysis patients with kidney transplant patients]. payesh Quarterly . 8(3) 279-287. (Persian). Sayin A et al (2007) Quality of life in hemodialysis, peritoneal dialysis, and transplantation patients. Transplantation Proceeding. 39(10) 3047-3053. Shah VS, et at (2006) Qualify of life and psychosocial factors in renal transplant Recipients. Transplantation Proceedings. 38(5) 1283-1285. Sugawara H et al (2008) Paradoxical depression in renal transplant recipient. Transplantation Proceeding. 40(10) 3448-3450. Szeifert L et al(2010) Symptoms of depression in kidney transplantations: A cross-sectional study. American Journal of Kidney Diseases (AJKD). 55(1)132-140. Toimamueang U et al (2003) Stress and coping strategies among renal transplant candidates in a stress and coping strategies among renal transplant candidates in a Thai medical center. Transplant Proceedings. 35(1) 292-3. Virzi A, et al (2007) Depression and quality of life in living related renal transplantation. Transplantation Proceedings. 39(6) 1791-1793. Weng LC, et al (2006) Effects of self-efficacy, self-care behaviors on depressive symptom of Taiwanese kidney transplant recipients. Journal of Clinical Nursing, 17(13) 1786-1794.

Sleep quality and its correlation with serum C-reactive protein level in hemodialysis patients.

Poor sleep quality is a common problem that can potentially predict mortality risk and quality of life in hemodialysis (HD) patients. Also, inflammation is a common feature in HD patients. To determine sleep quality and its correlation with serum C-reactive protein (CRP) level in these patients, we studied 132 chronic HD patients in two university-affiliated teaching hospitals in Sari, Iran during September 2010. Pittsburgh Sleep Quality Index was employed to assess the sleep quality of the patients in addition to CRP, albumin, cholesterol, phosphorus and hemoglobin levels. There were 104 (78.7%) patients who suffered from poor sleep quality. A significant correlation was found between serum CRP level and the patients' sleep quality (P <0.05). There was also a significant correlation between sleep quality and serum phosphorus and albumin levels and body mass index (P <0.05). Furthermore, a significant positive correlation existed between the different components of sleep quality and CRP (P <0.05). We conclude that there is a correlation between decreased sleep quality in HD patients and elevated CRP levels, which may have therapeutic implications.

Quality of sleep and its relationship to quality of life in hemodialysis patients.

Despite many advances in the treatment of chronic renal failure, the quality of sleep in patients who suffer from this disease is at the risk. The high prevalence of sleep disorders in hemodialysis patients, which is concomitant with physical, behavioral, and psychological problems, has always affected these patients' quality of life (QOL). This study aimed to determine the relationship between quality of sleep and quality of life in hemodialysis patients. By using a descriptive and correlational design, this study was conducted on 245 hemodialysis patients in 2012. Patients were selected by convenience sampling from the hemodialysis ward of four training hospitals of Tabriz and Maragheh. Quality of sleep was measured by the Pittsburgh Sleep Quality Index (PSQI), and the quality of life for patients was measured by the Kidney Disease Quality Of Life questionnaire (KDQOL-SF). 83.3% of hemodialysis patients had poor quality of sleep. Poor quality of life was significantly associated with poor quality of sleep. There was a significant negative correlation between global PSQI and important aspects of quality of life including physical health, symptoms and problems, the impact of kidney disease on daily life, burden of kidney disease, mental health, social support, and sexual function. The low quality of sleep in hemodialysis patients has an effect on the deterioration of their quality of life. Therefore, training, counseling, and advocacy programs should be developed to improve the patients' quality of sleep and quality of life, especially those with lower education level and income, and older people.

Patients’ direction, empowerment and quality of life in haemodialysis

The maintenance of an adequate of quality of life (QoL) represents a critical issue in the management of patients in haemodialysis and is also used to assess the effectiveness of health care programmes. The Consumer Direction Theory of Empowerment (CDTE) implies that greater patient direction in policy formulation and services delivery, together with an increased community integration, endorses a process which leads to a better QOL. The aim of the study was to test a contextualized version of CDTE in an ambulatory for patients in haemodialysis. Sixty-nine patients completed a questionnaire measuring the following variables: Patient direction, family integration, self-efficacy in managing the disease, mental and physical health. The results showed that patient direction and family integration have an indirect effect on QoL, through self-efficacy in managing the disease. The hypotheses were thus confirmed, providing support for the potential of CDTE in the context of health services for haemodialysis patients. Implications for the implementation of health programmes aimed at improving QoL of patients in haemodialysis are discussed, including interventions focused on psychological and contextual factors.

Quality of life scores should be compared before and after patients have undergone dialysis

lettersQuality of life scores should be compared before and after patients have undergone dialysis Hakan Sarlak, Sait Demirkol, Sevket Balta, Mustafa Cakar, Omer Kurt, and Muharram Akhan Hakan Sarlak Department of Internal Medicine, Gulhane Medical Academy, Ankara, Turkey Search for more papers by this author , Sait Demirkol Department of Cardiology, Gulhane Medical Academy, Ankara, Turkey Search for more papers by this author , Sevket Balta Department of Cardiology, Gulhane Medical Academy, Ankara, Turkey Search for more papers by this author , Mustafa Cakar Department of Internal Medicine, Gulhane Medical Academy, Ankara, Turkey Search for more papers by this author , Omer Kurt Department of Internal Medicine, Gulhane Medical Academy, Ankara, Turkey Search for more papers by this author , and Muharram Akhan Department of Internal Medicine, Gulhane Medical Academy, Ankara, Turkey Search for more papers by this author Published Online::3 Oct 2013https://doi.org/10.5144/0256-4947.2013.510aSectionsPDF ToolsAdd to favoritesDownload citationTrack citations ShareShare onFacebookTwitterLinked InRedditEmail AboutIntroductionTo the Editor: We intentionally read the article “Quality of life (QoL) in hemodialysis and peritoneal dialysis patients in Saudi” written by Wakeel et al with great interest.1 They concluded that the quality of life (QoL) was better among peritoneal dialysis (PD) than hemodialysis (HD) patients in all domains except physical domain. PD patients spent more quality time and were more satisfied than HD patients.1In the last years, advances in dialysis procedures and new guidelines to treat the chronic renal failure patients have improved their treatment and prolonged their lives. At the same time, the concept of health-related quality of life (HRQoL) strengthened as a new goal to be achieved. The current dialysis guidelines enforce treatments to achieve similar outcomes in the long run, independently of the choice of dialysis treatment.2 Manns et al. in their study concluded that there was no significant difference in HRQoL for prevalent end-stage renal disease patients treated with HD or PD.3 In another study, Wu et al. concluded that that PD did not seem to produce a better QoL than HD for patients who imitated renal replacement therapy. 4 Ginieri-Coccossis. et al. in their study concluded that the results provided evidence that patients in HD treatment modality, particularly those with many years of treatment, experienced a more compromised QoL in comparison to PD patients.5 The results may change due to sociodemographic characteristics of patients. We think that the comparison of the two groups could be more meaningful if the QoL is measured before and after patients are undergone dialysis. Another point of discussion could be that the variations in study results may vary upon longer follow-up durations of these patients.ARTICLE REFERENCES:1. Al Wakeel Jamal, Al Harbi Ali, Bayoumi Magda, Al-Suwaida Karaem, Al Ghonaim Mohammed, Mishkirye Adel. "Quality of life in hemodialysis and peritoneal dialysis patients in Saudi Arabia" . Ann Saudi Med. 2012; 32(6):570-574. Google Scholar2. Arenas Valquiria Greco, Barros Luciene Fatima Neves Monteiro, Lemos Francine Barros. "Quality of Life: Comparison between patients on automated peritoneal dialysis and patients on hemodialysis" . Acta Paul Enferm. 2009; 22(Especial-Nefrologia)535-9. Google Scholar3. Manns B, Johnson JA, Taub K, Mortis G, Ghali WA, Donaldson C. "Quality of life in patients treated with hemodialysis or peritoneal dialysis: what are the important determinants?" Clin Nephrol. 2003; 60(5):341-51. Google Scholar4. Wu AW, Fink NE, Marsh-Manzi JV, Meyer KB, Finkelstein FO, Chapman MM, Powe NR. "Changes in quality of life during hemodialysis and peritoneal dialysis treatment: generic and disease spesific measures" . J Am Soc Nephrol. 2004; 15(3):743-53. Google Scholar5. Ginieri-Coccossis M, Theofilou P, Synodinou C, Tomaras V, Soldatos C. "Quality of life, mental health and health beliefs in hemodialysis and peritoneal dialysis patients: Investigating differences in early and later years of current treatment" . BMC Nephrology. 2008November149-14. Google Scholar Previous article Next article FiguresReferencesRelatedDetails Volume 33, Issue 5September-October 2013 Metrics History Published online3 October 2013 InformationCopyright © 2013, Annals of Saudi MedicineThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.PDF download

Effect of baby oil on pruritus, sleep quality, and quality of life in hemodialysis patients: pretest-post-test model with control groups.

To assess the effect of baby oil on pruritus, sleep quality, and quality of life in hemodialysis (HD) patients. This pretest-post-test model with control groups study was conducted in HD units in two different provinces in eastern Turkey. The study group consisted of a total of 70 patients receiving HD treatment who met the inclusion criteria, 35 being in the intervention group and 35 in the control group. After the patients in both groups were informed about the study, they were administered a questionnaire, the Severity Scale, Visual Analog Scale, the Pittsburgh Sleep Quality Index, and the SF-36 Quality of Life Scale. Following the administration of baby oil to the patients in the intervention group three times a week for a period of 1 month, the same scales were repeated to explore their pruritic status, sleep quality, and quality of life. The same scales were repeated also for the patients in the control group 1 month later but without administering any baby oil. When the Itch Severity Scale, Visual Analog Scale, Pittsburgh Sleep Quality Index, and SF-36 Quality of Life Physical and Mental Component scores of the patients in the control and intervention groups before and after the intervention were compared, the differences in the change were found to be statistically significant in favor of the intervention group (P < 0.05). It was found in this study that administration of baby oil had positive effects on itching, quality of life, and sleep quality in HD patients who had itching complaints.

Quality of life in chronic haemodialysis and peritoneal dialysis patients in Turkey and related factors

Turkey is the fifth country in Europe with regard to the number of patients receiving haemodialysis (HD). However, only a limited number of studies have comparatively investigated the factors that affect quality of life in haemodialysis and peritoneal dialysis (PD) patients in Turkey. The purpose of the study was to investigate the factors that affect quality of life in haemodialysis and peritoneal dialysis patients, as well as providing a comparison of quality of life between these groups. In this cross-sectional study, Quality of Life Scale and a data form was completed by 300 dialysis patients who received treatment at five hospital-based dialysis units in Istanbul, Turkey. The data were evaluated using arithmetic mean values, standard deviations, minimums, maximums, percentages, independent groups t-tests, Spearman correlation analyses and one-way variance analyses. The quality of life values in peritoneal dialysis patients were found to be higher than those of haemodialysis patients (P < 0.05). It was concluded that the quality of life in chronic dialysis patients was affected by various factors.

Bone Pain Assessment and Relationship with Parathyroid Hormone and Health-Related Quality of Life in Hemodialysis

Renal osteodystrophy is a common problem in renal failure patients. Bone pain is a common manifestation of renal osteodystrophy. The aim of the study was to assess the intensity of chronic bone pain via visual analog scale (VAS) and its relationship with parathyroid hormone, health-related quality of life (HRQoL), and depression in hemodialysis patients. Ninety-five patients recruited were asked to rate chronic bone pain via VAS. Depressive symptoms and HRQoL were assessed by Beck Depression Inventory (BDI) and Short-Form 36, respectively. VAS was positively correlated with intact parathyroid hormone (r = +0.322, p = 0.001), phosphorus (r = +0.300, p = 0.003), alkaline phosphatase (r = +0.275, p = 0.009), and negatively correlated with physical component (r = –0.320, p = 0.002) and mental component summary scores (r = –0.247, p = 0.016). In multivariate linear regression analysis, logVAS was independently associated with serum phosphorus (β = 0.072, 95% confidence interval: 0.020–0.123, p = 0.007), log intact parathyroid hormone (β = 0.176, 95% confidence interval: 0.041–0.310, p = 0.011), and physical component summary score (β = –0.018, 95% confidence interval: –0.031–(–0.005), p = 0.008). VAS is correlated with bone metabolism markers, namely, intact parathyroid hormone, and may be used to assess the intensity of chronic bone pain. The intensity of chronic bone pain is related with HRQoL in hemodialysis patients.

Survival of the First Arteriovenous Fistula in 96 Patients on Chronic Hemodialysis

Native arteriovenous fistula (AVF) represents the best vascular approach for chronic hemodialysis. The aim of this study was to determine the survival of the first AVF and to identify the factors responsible for poor AVF survival. A retrospective study was conducted on 96 chronic hemodialysis patients benefiting from the creation and cannulation of their first AVF at our center, with a minimum follow-up period of 1 year. We collected demographic, clinical, and biological data, as well as analyzed the following AVF characteristics: anatomic site, cannulation time, survival, and complications. To identify the predictive factors of poor AVF survival, we defined and compared two groups of patients on the basis of whether they lost their first AVF during the evolution. Patients' mean age was 42.1 ± 13 years, with predominantly female patients. Mean AVF cannulation time was 17.5 ± 24 days. AVF loss was mainly related to thrombosis in 29% of the cases and stenosis in 9.4%. AVF survival was 87%, 77%, 71%, 67%, and 64% after 1, 3, 5, 8, and 10 years of hemodialysis, respectively. In our study, the main factors associated with AVF loss were lengthy jugular venous catheters placement (p = 0.004), short AVF cannulation time after its creation (p = 0.03), and hypotension episodes during dialysis (p = 0.03). Long-term survival and quality of life in hemodialysis depend on an appropriate dialysis carried out-thanks to a correct vascular approach! According to the previously published data, survival of the first AVF can vary between 10% and 36% at 10 years. In our study, survival of the first native AVF was satisfying because it reached 64% at 10 years. Early AVF creation and prevention and management of its complications remain the safest and most comfortable solution to ensure AVF survival and thus a satisfying survival and quality of life in chronic hemodialysis patients.

Associação entre exercício físico e qualidade de vida de pacientes em hemodiálise

INTRODUÇÃO: Vários estudos têm demonstrado a relação entre a prática de exercício físico (EF) e a melhora da qualidade de vida (QV) da população geral. Muitos fatores contribuem para a piora da QV dos pacientes em hemodiálise (HD) e com freqüência encontramos nestes indivíduos uma baixa aptidão para a prática de EF. Nosso objetivo neste trabalho foi estudar a associação do EF com a QV do paciente em HD. MÉTODOS: Estudo transversal com 115 pacientes em hemodiálise no Hospital das Clínicas Samuel Libânio – Pouso Alegre, MG, divididos em 2 grupos: GS: pacientes sedentários; GA: pacientes que realizavam exercício físico regular. Para medida da QV foi utilizado o instrumento SF-36. Foram coletados dados clínicos, socioeconômicos e laboratoriais. Para a análise dos resultados foi utilizada estatística analítica e descritiva. Adotamos 0,05 como nível de rejeição da hipótese de nulidade. RESULTADOS: Não encontramos diferenças entre idade (GS: 53,3 ± 13,0; GA:53,8 ± 13,8); etnia (56% de caucasianos em GS e 60% em GA); hemoglobinemia (GS: 10,3 ± 1,7; GA:10,7 ± 1,9); índice de massa corpórea (GS: 23,6 ± 4,3; GA:24,1 ± 3,8). Quando comparamos os escores dos domínios do SF-36 observamos diferença entre capacidade funcional (GS:53,0 ± 27,5 e GA: 72,4 ± 20,9; p = 0,0001); aspectos físicos (GS:43,1±41,9 e GA: 56,4 ± 33,9; p = 0,05); dor (GS:60,1 ± 27,9 e GA: 70,4 ± 22,8; p = 0,03); vitalidade (GS:53,3 ± 25,1 e GA: 66,1 ± 21,2; p = 0,05) e saúde mental (GS:65,0 ± 26,7 e GA: 76,2 ± 19,2; p = 0,006). CONCLUSÃO: observamos uma relação direta do exercício físico com a qualidade de vida, mas não pudemos estabelecer uma relação de causa e efeito com este estudo

Perceived Social Support and Quality of Life in Iranian Hemodialysis Patients

To describe the relationship between perceived social support and the quality of life in hemodialysis patients from an Islamic cultural background in Iran. A cross-sectional, correlational design was used. Data were collected in hemodialysis units affiliated to Iran University of Medical Sciences. Two hundred and two Muslim hemodialysis patients were selected by census during 2007. The Persian versions of the Personal Resources Questionnaire 85 (PRQ-85) Part II and the Ferrans and Powers Quality of Life Index-dialysis version were used. The data were analyzed using chi-square test and Spearman's rho correlation coefficients. There were a statistically significant relationship between perceived social support and health-functioning (r = .65, p < or = .05), socioeconomic (r = .67, p < or = .05), psychological-spiritual (r = .63, p < or = .05), and family subscales of quality of life (r = .51, p < or = .05). Total quality of life was also significantly correlated with perceived social support (r = 0.72, p= .00). Perceived social support is associated with quality of life in Iranian hemodialysis patients. It is important to reflect on the impact of culture and religion of Iran on quality of life of hemodialysis patients and their perceived social support.

Improving quality of life in hemodialysis: impact of an occupational therapy program

The aim of this study was to verify the impact of an occupational therapy (OT) program on the Quality of Life (QoL) of hemodialysed patients. Sixty patients with chronic renal disease undergoing regular hemodialysis were involved. A study group composed of 20 subjects was submitted to an OT program while a control group with 40 subjects followed conventional treatment. Upon analyzing the group as a whole, the study group showed significant improvement in mental health (p = 0.05) and the control group showed a deterioration in the pain domain (p = 0.04). No significant change was observed when comparing groups. When the group was divided between the genders, female patients in the study group scored improvements in the categories of Pain, Emotional Aspects, and Mental Health, whereas no corresponding significant change was found in the control group. A significant improvement was observed in the pain domain (p < 0.05) when comparing groups. In male patients, no significant changes were observed in the study group whereas a significant deterioration occurred in functional capacity in the control group. No significant changes were observed when comparing groups. The conclusion is that to improve their QoL occupational therapy may be included in the therapeutic approach for patients under hemodialysis.

Effects of Exercise Intervention on Physical Fitness and Health-relalted Quality of Life in Hemodialysis Patients

The purpose of this study was to investigate the effect of stretching, muscle strengthening, and walking exercise on the cardiopulmonary function and health-related quality of life in hemodialysis patients. Twenty-one patients in the intervention and the control group participated in the exercise respectively on maintenance hemodialysis at four university hospitals. The exercise was composed of 20 to 60 min per session, 3 sessions a week for 12 weeks. The effect of exercise was assessed by cardiopulmonary function (peak oxygen uptake, peak ventilation, peak respiration rate, maximal heart rate, and exercise duration) using a cycle ergometer. Grip strength was measured by dynamometer, and flexibility was measured by sit and reach measuring instrument. Health-related quality of life was measured using Medical Outcomes Study Short Form-36. Peak oxygen uptake, peak ventilation, peak respiration rate, exercise duration, grip strength, flexibility, and physical component scale were significantly improved in the intervention group after 12 week's exercise compared to the control group. These findings indicate the exercise can improve cardiopulmonary function, grip strength, flexibility, and physical component scale of health-related quality of life in hemodialysis patients.

Quality of life is not related with liver disease severity but with anemia, malnutrition, and depression in HCV‐infected hemodialysis patients

Hepatitis C virus (HCV) infection may deteriorate quality of life. The relationship between HCV infection and quality of life in hemodialysis (HD) patients is unknown. The demographic characteristics, comorbidities, biochemical parameters, and Malnutrition-Inflammation Score (MIS) were recorded. Child-Pugh classification, Beck Depression Inventory, and SF-36 were performed. Liver histopathology was examined. Thirty-two patients (21 Child-Pugh-A, 11 Child-Pugh-B) were included. There was high-grade portal necroinflammatory activity in 14, high-grade lobular necroinflammatory activity in 26, and hepatic fibrosis in 19 patients. Three patients had cirrhosis. Patients with a high stage of liver fibrosis had lower social functioning scores than patient with a low stage of fibrosis (P= 0.011). The only correlation was between aspartate aminotransferase and the physical function subscale (r=-0.395, P= 0.025). None of the SF-36 scores differed between Child-Pugh A and B patients. Instead, most of the SF-36 subscale and summary scores were related with hemoglobin, albumin, MIS and Beck Depression Score. Quality of life in HCV-infected HD patients was independent of liver disease severity anchors, but was correlated with anemia, malnutrition, and depression.

A Comparison of Quality of Life in Haemodialysis and Peritoneal Dialysis Patients

Decreased quality of life of end-stage renal disease is further compromised by renal function replacement treatments such as haemodialysis (HD) and peritoneal dialysis (PD). Poor quality of life negatively affects treatment outcome. This study compared quality of life between HD and PD patients. Quality of life in 15 HD and 15 PD patients at a South African renal unit was compared using the SF-36 short form. There was no significant difference between HD and PD patients for total SF-36 score, but HD subjects reported more pain. Quality of life is similar in HD and PD patients, with the exception of higher pain levels in HD patients.

Quality of Life in Hemodialysis, Peritoneal Dialysis, and Transplantation Patients

Quality of life (QOL) has recently been explored as one of the main outcomes of renal replacement therapy. In this study, we sought to compare three groups of patients—hemodialysis, peritoneal dialysis, and transplantation—with regard to QOL. Methods Seventy-five hemodialysis, 41 peritoneal dialysis and 20 transplant patients were given Patient Information Form, Short Form Health Survey 36, Beck Depression Inventory, and State-Trait Anxiety Inventory. Results The QOL scores of the three groups were similar and lower than the normal Turkish population. Depression and anxiety levels had significant and negative effects on QOL of hemodialysis and peritoneal dialysis, but not transplant patients. In a multiple regression analysis, being male, being older than 46 years, living with family, having middle-higher income, having renal disease for a longer time, having a longer period of dialysis treatment, having comorbid illness, having not enough illness knowledge, and having higher levels of depression and of anxiety significantly correlated with a worse quality of life. Conclusions The three forms of renal replacement therapy did not differ with regard to QOL. Among the factors that seem to affect QOL, psychological status and treatment/illness knowledge had the most significant correlation. The underlying mechanisms need to be clarified.