Today, the matters of ensuring the safety of human life in a polluted environment, quality control of agricultural raw materials, food and the parameters of various environments is becoming increasingly urgent, especially in connection with the development of nanotechnology and nanoindustry. Therefore, high-precision measurements of aerosol parameters and the metrology of air weights are directly connected with the global problem of monitoring the safety of the use of nanotechnology. Since it’s been created the Russian State Primary Standard - GET 163 was modified two times to support the demanded measurement accuracy in this area in Russia. The standard has reproduced, maintained and transferred values of units of particle size, number particle concentration, mass concentration of aerosol particles, and, since 2020, units of electrophoretic mobility and zeta potential of particles in liquid media