This paper proposes the use of quadrature space shift keying (QSSK) modulation for wireless sensor networks (WSNs). QSSK is a multiple input multiple output communication protocol that attracted substantial interest due to several promised inherent advantages. It has been shown in literature that QSSK scheme achieves high spectral efficiency with low average error probability, high energy efficiency, and very simple transmitter and receiver architectures. Hence, its use in WSNs is very promising to ameliorate the major limitations of such networks. The performance of a WSN with QSSK modulation and in the presence of co-channel interference is studied in this paper. A closed form expression for the average pair wise error probability is derived and used to obtain a tight upper bound on the overall average bit error ratio. Obtained results verified the superiority of QSSK scheme as compared to traditional modulation techniques especially for high spectral efficiency.