Q-switched ruby, alexandrite, and Nd:YAG lasers, which have become the treatments of choice for tattoos, have been associated with limited local morbidity and no systemic effects. This report describes two cases of widespread allergic reactions to tattoo pigment apparently induced by Q-switched ruby and Nd:YAG lasers. In one case, a 26-year-old woman underwent Q-switched ruby and Nd:YAG laser treatment of a multicolored decorative tattoo. Three weeks after treatment she …