Pyridazine Research Articles

Synthesis and transformation of certain pyridazine cyclonucleosides

Synthesis and transformation of certain pyridazine cyclonucleosides

縮合環を有するPyridazine誘導体に関する研究(第1報)5,8-Dichloropyrido-[2,3-d]pyridazineとCarbanionとの反応

縮合環を有するPyridazine誘導体に関する研究(第1報)5,8-Dichloropyrido-[2,3-d]pyridazineとCarbanionとの反応

1,2-Dimethyl-5-trifluoroacetyl-2H-cyclopenta[d]pyridazine; addendum

1,2-Dimethyl-5-trifluoroacetyl-2<i>H</i>-cyclopenta[<i>d</i>]pyridazine; addendum

1,2-Dimethyl-5-trifluoroacetyl-2H-cyclopenta[d]pyridazine

1,2-Dimethyl-5-trifluoroacetyl-2H-cyclopenta[d]pyridazine

Photoalkylation of s-triazolo[4,3-b]pyridazine with alcohols and glycols

Photoalkylation of s-triazolo[4,3-b]pyridazine with alcohols and glycols

Synthesis, Structure and Properties of Methyl-azuleno[1,8-cd]pyridazines

Synthesis, Structure and Properties of Methyl-azuleno[1,8-cd]pyridazines

A synthesis of annulated pyridazines by cycloaddition of azodicarboxylates to vinylpyridines

A synthesis of annulated pyridazines by cycloaddition of azodicarboxylates to vinylpyridines

ChemInform Abstract: POSSIBLE GENERATION OF A FLUORINATED AZACYCLOBUTADIENE

AbstractDie Belichtung des Pyridazins (I) ergibt über (II) die Verbindungen (III), (VIII) und (IX) sowie über das Azacyclobutadien (IV) die Verbindungen (V)‐(VII).

Studies on pyridazines. XXVI. The reaction of substituted N-acetyliminopyridazinium ylides with benzyne.

Studies on pyridazines. XXVI. The reaction of substituted N-acetyliminopyridazinium ylides with benzyne.

ChemInform Abstract: STUDIES ON THE SYNTHESES OF HETEROCYCLIC COMPOUNDS. DCLXIII. THE REACTION OF PYRIDONE DERIVATIVES WITH DIAZOALKANE

The reaction of 3-carboxy-1, 2-dihydro-1-methyl-2-oxopyridine (V) with diazomethane afforded 6, 7-dihydro-1, 6-dimethyl-7-oxopyrazolo [3, 4-c] pyridine (VI), 4, 5, 6, 7-tetrahydro-1, 6-dimethyl-7-oxopyrazolo [3, 4-c] pyridine (VII), and 1, 2-dihydro-3-methoxycarbonyl-1, 4-dimethyl-2-oxopyridine (VIII). 1-Ethyl-6, 7-dihydro-3, 6-dimethyl-7-oxopyrazolo [3, 4-c] pyridine (XXI), 8a-ethoxycarbonyl-1, 4, 4a, 7, 8, 8a-hexahydro-3, 4, 7-trimethyl-8-oxopyrido [3, 4-c] pyridazine (XXII), and 3-ethoxycarbonyl-4-ethyl-1, 2-dihydro-1-methyl-2-oxopyridine (XXIII) were obtained from the reaction of compound (V) with diazoethane. The treatment of 4-carboxy-1, 2-dihydro-1-methyl-2-oxopyridine (XXVIII) with diazomethane gave 1, 2-dihydro-4-methoxycarbonyl-1-methyl-2-oxopyridine (XXIX), 6-methoxycarbonyl-3-methyl-2-oxo-3-azabicyclo [4. 1. 0] hept-4-ene (XXX), and 1, 2-dihydro-4-methoxycarbonyl-1, 3-dimethyl-2-oxopyridine (XXXI). The reaction of compound (XXIX) with diazoethane afforded 3-ethyl-1, 2-dihydro-4-methoxycarbonyl-1-methyl-2-oxopyridine (XXXII), 6α-methoxycarbonyl-3, 7β-dimethyl-2-oxo-3-azabicyclo [4, 1, 0]-hept-4-ene (XXXIII), and 1-ethyl-6-methoxycarbonyl-3, 7-dimethyl-2-oxo-3-azabicyclo [4. 1. 0] hept-4-ene (XXXIV). In case of the treatment of 5-carboxy-1, 2-dihydro-1-methyl-2-oxopyridine (XXXV) and 1, 5-dihydro-1, 5-dioxo-3H-oxazolo [3, 4-a] pyridine (XXXVIII) with diazomethane, 1, 2-dihydro-5-methoxycarbonyl-1-methyl-2-oxopyridine (XXXVI) and 1, 2-dihydro-6-methoxycarbonyl-1-methyl-2-oxopyridine (XXXIX) were obtained, respectively.

A New Alkylation of Pyridazines with Nitromethane and Nitroethane

A New Alkylation of Pyridazines with Nitromethane and Nitroethane

Possible generation of a fluorinated azacyclobutadiene

Photolysis of a fluorinated pyridazine gives products which are dimers of a possible intermediate azacyclobutadiene (azete) derivative.

Pyridazines VIII. Some 6‐aryl‐3‐(basically‐substituted) pyridazines

Pyridazines VIII. Some 6‐aryl‐3‐(basically‐substituted) pyridazines

Synthèse du mèthyl‐1 diformyl‐2,3 pyrrole, de la méthyl‐1 pyrrolo[2,3‐d] pyridazine et de la méthyl‐1 oxo‐6 (6h)cycloheptatrieno[b] pyrrole

AbstractThis communication describes the synthesis of l‐methyl‐2,3‐diformylpyrrole. This new compound is used to prepare a new heterocycle, l‐methylcyclohepta[b]pyrrol‐6‐one and thus allows a new synthesis of l‐methylpyrrolo[2,3‐d]pyridazine.

Studies on Heterocyclic Compounds. XIX. Synthesis of Furo [2, 3-&lt;I&gt;d&lt;/I&gt;]-pyridazine Derivatives.(7). Nitration of Furo [2, 3-&lt;I&gt;d&lt;/I&gt;] pyridazines in the 5 Position

Studies on Heterocyclic Compounds. XIX. Synthesis of Furo [2, 3-&lt;I&gt;d&lt;/I&gt;]-pyridazine Derivatives.(7). Nitration of Furo [2, 3-&lt;I&gt;d&lt;/I&gt;] pyridazines in the 5 Position

Convesion of Pyridazines to other Compounds

Convesion of Pyridazines to other Compounds

The structures of the 1:1 complexes of CuCN with pyridazine and with 4-cyanopyridine

The structures of the 1:1 complexes of CuCN with pyridazine and with 4-cyanopyridine

The Metabolism of 2-Phenyl-5, 8-Dimorpholino-Pyrimido(4,5-D)Pyridazine (DS-210) in Rats and Mice

The Metabolism of 2-Phenyl-5, 8-Dimorpholino-Pyrimido(4,5-D)Pyridazine (DS-210) in Rats and Mice

Addition of 6‐azidotetrazolo[1,5‐b] pyridazine to acrylates

Addition of 6‐azidotetrazolo[1,5‐<i>b</i>] pyridazine to acrylates

Studies on Heterocyclic Compounds. XV. Synthesis of Furo [2, 3-&lt;I&gt;d&lt;/I&gt;] pyridazine Derivatives.(4). Synthesis of 2-[2-(5-Nitro-2-furyl) vinyl]-4, 7-dichlorofuro-[2, 3-&lt;I&gt;d&lt;/I&gt;] pyridazine and Related Compounds by the Wittig Reaction

Studies on Heterocyclic Compounds. XV. Synthesis of Furo [2, 3-&lt;I&gt;d&lt;/I&gt;] pyridazine Derivatives.(4). Synthesis of 2-[2-(5-Nitro-2-furyl) vinyl]-4, 7-dichlorofuro-[2, 3-&lt;I&gt;d&lt;/I&gt;] pyridazine and Related Compounds by the Wittig Reaction