Pursuit Of Precision Research Articles

Hierarchical Assembly of High-Nuclearity Copper(I) Alkynide Nanoclusters: Highly Effective CO2 Electroreduction Catalyst toward Hydrocarbons.

The pursuit of precision in the engineering of metal nanoparticle assemblies has long fascinated scientists, but achieving atomic-level accuracy continues to pose a significant challenge. This research sheds light on the hierarchical assembly processes of two high-nuclearity Cu(I) nanoclusters (NCs). By employing a multiligand cooperative stabilization strategy, we have isolated a series of thiacalix[4]arene (TC4A)/alkynyl coprotected Cu(I) NCs (Cux, where x = 9, 13, 17, 22). These NCs are intricately coassembled from the fundamental building units of {Cu4(TC4A)} and alkynyl-stabilized Cu5L6 in various ratios. By capturing active anion templates such as O2-, Cl-, or C22- that are generated in situ, we have further explored the secondary structural self-assembly of these clusters. Cu13 serves as a secondary assembly module for constructing Cu38 and Cu43, which exhibit the highest nuclearity reported to date among Cu(I) NCs encased in macrocyclic ligands. Notably, Cu38 demonstrates an impressive Faradaic efficiency of 62.01% for hydrocarbons at -1.57 V vs RHE during CO2 electroreduction, with 34.03% for C2H4 and 27.98% for CH4. This performance establishes it as an exceptionally rare, large, atomically precise metal NC (nuclearity >30) capable of catalyzing the formation of highly electro-reduced hydrocarbon products. Our research has introduced a new approach for constructing high-nuclearity Cu(I) NCs through a hierarchical assembly method and investigating their potential in the electrocatalytic transformation of CO2 into hydrocarbons.

“Where Treasures Arise:” Mining Knowledge, Mining Sites, and the Spatial Rationalities of Mineral Resources in Qing China

A comparison between nineteenth-century Europe and Qing-dynasty Yunnan reveals how mining knowledge shaped ways of understanding and organizing mineral resources in space. In Europe, stratigraphic geology, prospecting technologies, and mapmaking generated new rationales to understand mineral resources and their distribution in space, a process entangled with the rise of the nation-state and its exercise of power over the qualities of its territory. In Qing China, due to the lack of modern mining and geological knowledge and the gulf between miners and officials, mineral resources and their distribution were understood purely by reference to mining sites, in particular chang (廠 mine, literally “factory”). Territorial administration, taxation, and transportation were the primary mechanisms utilized to organize these mining sites, and through them governments and officials controlled information on mineral resources and envisaged their spatial distribution. The map was not an authoritative tool for presenting mineral resources in space but instead demonstrated more the Qing's hegemony and local governance than the pursuit of precision. Drawing upon Margo Huxley's insights into spatial rationality, this study problematizes space in the epistemic understanding of mineral resources in a pre-modern context and reassesses historical implications of the legibility of nature for political rationalities governing natural things.

In the Pursuit of Precision: Novel Target Therapies Revolutionizing SLE Care

Systemic lupus erythematosus (SLE) is a chronic, autoimmune, immune complex-mediated disease affecting mainly females at a young age. The disease etiology is still unknown, and different genetic and epigenetic factors related to disease onset and manifestations are being explored. The standard treatment regimen for SLE includes the long-term use of corticosteroids and non-specific immunosuppressive agents, often limited by co-morbidities or related side effects. However, recent advances in disease pathogenesis clarifying the role of inflammatory cytokines, chemokines, immune cells, and co-stimulation molecules have made a more practical, targeted approach possible, leading to personalized treatment strategies. This review summarizes current knowledge about SLE-targeted therapies in clinical practice.

Features of English for Science and Technology and Translation Strategies under the Perspective of Faithfulness, Expressiveness and Elegance ---- A Case Study of Geological Translation

In the contemporary era, there is a burgeoning trend of intercultural communication among nations, prominently encompassing interactions within the scientific and technological (Sci. & Tech) domain. Within China, there has been a conspicuous dearth in the realm of Science and Technology translation, notably concerning the precise rendition of intricate professional knowledge across specific specialized fields and the requisite translation calibre. This deficiency has been accentuated by the absence of pertinent theoretical frameworks. Within this context, this research delves into the stylistic attributes of English for Science and Technology (EST) and elucidates translation strategies within the framework established by Yan Fu. Initially, the study scrutinizes the distinctive characteristics of EST, encompassing lexicon, syntax, and textual structures. Subsequently, it extrapolates these findings to the domain of Sci. & Tech translation. The ensuing section chronicles the evolution of domestic translation studies, culminating in the exposition of Yan Fus translation standards-namely, faithfulness, expressiveness, and elegance. The paper concludes by summarizing the targeted translation strategies for Sci. & Tech translation, encompassing meticulous preparation, the pursuit of precision, and rigorous review and refinement processes.

Fuzzy Deep Medical Diagnostic System: Gray Relation Framework and the Guiding Functionalities for the Professional Sports Club Social Responsibility

Fuzzy deep medical diagnostic system based on gray relation framework and the guiding functionalities for the professional sports club social responsibility is proposed in this paper. Medical high-tech has two features, namely formal logic and mathematics. That is to say, they use formal logic to build the theoretical system, which requires that the principles of the medical science and technology are defined clearly in concept, the reasoning is rigorous and logical and its mathematics requires its pursuit of precision in the work, and a mathematical language to reveal the internal relations between the present images. Medical technology for tissue damage mild disease is often unchecked, when the patient’s own symptoms and feelings are often more accurate than the instrument. Inspired by this, this paper integrates the deep learning model to construct the intelligent diagnostic system. The gray relation is designed to improve the traditional CNN model and the revised algorithms also combine the sensitive data analysis framework. At the meanwhile, application scenario on the professional sports club social responsibility is demonstrated. Experimental results prove the effectiveness of the designed system. The diagnostic accuracy has reached 98.38% which performs better compared with the other state-of-the-art methodologies.

Flavor physics: Precision as an avenue to discovery

This paper describes the work pursued in the years 2008–2013 on improving the Standard Model prediction of selected flavor-physics observables. The latter includes: (1) [Formula: see text], that quantifies indirect CP violation in the [Formula: see text] system and (2) the very rare decay [Formula: see text], recently measured at the LHC. Concerning point (1), the paper describes our reappraisal of the long-distance contributions to [Formula: see text],[Formula: see text] that have permitted to unveil a potential tension between CP violation in the [Formula: see text]- and [Formula: see text]-system. Concerning point (2), the paper gives a detailed account of various systematic effects pointed out in Ref. 4 and affecting the Standard Model [Formula: see text] decay rate at the level of 10% — hence large enough to be potentially misinterpreted as nonstandard physics, if not properly included. The paper further describes the multifaceted importance of the [Formula: see text] decays as new physics probes, for instance how they compare with [Formula: see text]-peak observables at LEP, following the effective-theory approach of Ref. 5. Both cases (1) and (2) offer clear examples in which the pursuit of precision in Standard Model predictions offered potential avenues to discovery. Finally, this paper describes the impact of the above results on the literature, and what is the further progress to be expected on these and related observables.

BERGSON’S METHOD OF PROBLEMATISATION AND THE PURSUIT OF METAPHYSICAL PRECISION

The aim of this paper is to excavate and analyse Henri Bergson’s “problematic” thinking. This task will be prosecuted through a close reading of his two-part introduction to The Creative Mind – the text in which Bergson most concisely and conclusively articulates the “problematic” character of his work. As I will attempt to show in this paper, Bergson’s work is “problematic” in two respects, one to do with methodology and the other metaphysics. These two, furthermore, are intimately entwined: on the one hand, Bergson’s method of problematisation emerges from the findings of his metaphysical inquiries, while on the other, it is through the application of his problematising method that the findings of his metaphysical inquiries can be deemed as reliably accurate. In exploring this “problematic” intersection of Bergson’s methodology and metaphysics, I will first discuss what Bergson takes to be one of the biggest problems for philosophy: the lack of adequate “precision.” As we will see, many of the major themes and concepts of Bergson’s work, such as duration and intuition, both spring from and converge on his efforts to address this problem. The pursuit of precision also calls for a “problematic approach” that is appropriate for the metaphysical reality it seeks to handle – an approach I will outline in the second part of this paper. This will be followed by a discussion of how Bergson’s problematic method/metaphysics involves a critique of what he refers to as “fictitious,” “phantom” or “pseudo-problems.” This “negative” aspect of Bergsonian problematisation will then be reconsidered in the final part of the paper alongside its “positive” dimension – posing problems in terms of time.

Cervical Cancer Screening

Recent changes in cervical cancer screening and management guidelines reflect our evolving knowledge about cervical carcinogenesis. In the pursuit of precision, however, decision-making has become complicated. We provide an overview of cervical cancer screening with a focus on what clinicians can do to maximize screening benefits while minimizing screening harms. The approach relies on categorizing women at each step in the screening process by their estimated risk of high-grade precancerous lesions and cervical cancer. Current screening guidelines are designed to find a reasonable balance between benefits and harms by recommending less screening in most women. Current management guidelines are designed to assure consistent decisions regarding referral to colposcopy. After initial colposcopy, we outline three major management options based on risk assessment. For treatment, we recommend ablational procedures when appropriate because they are similarly effective, less costly, and potentially safer than excisional procedures. We advise caution in adopting new screening strategies until they demonstrate cost-effective patient-centered improvements compared with current strategies. Clinicians can maximize their effect on cervical cancer prevention by being attentive to guidelines, assuring that women have access to appropriate human papillomavirus vaccination and providing low-cost, high-quality screening and treatment.

In Pursuit of Precision: The Calibration of Minds and Machines in Late Nineteenth-century Psychology

A prominent feature of late nineteenth-century psychology was its intense preoccupation with precision. Precision was at once an ideal and an argument: the quest for precision helped psychology to establish its status as a mature science, sharing a characteristic concern with the natural sciences. We will analyse how psychologists set out to produce precision in 'mental chronometry', the measurement of the duration of psychological processes. In his Leipzig laboratory, Wundt inaugurated an elaborate research programme on mental chronometry. We will look at the problem of calibration of experimental apparatus and will describe the intricate material, literary, and social technologies involved in the manufacture of precision. First, we shall discuss some of the technical problems involved in the measurement of ever shorter time-spans. Next, the Cattell-Berger experiments will help us to argue against the received view that all the precision went into the hardware, and practically none into the social organization of experimentation. Experimenters made deliberate efforts to bring themselves and their subjects under a regime of control and calibration similar to that which reigned over the experimental machinery. In Leipzig psychology, the particular blend of material and social technology resulted in a specific object of study: the generalized mind. We will then show that the distribution of precision in experimental psychology outside Leipzig demanded a concerted effort of instruments, texts, and people. It will appear that the forceful attempts to produce precision and uniformity had some rather paradoxical consequences.

A War Technology: America's Pursuit of Precision Bombing,1910-1945 . Stephen L. McFarland. Smithsonian Institution Press, Washington, DC, 1995. xx, 312 pp., illus. $29.95. Smithsonian History of Aviation Series.

A War Technology: <i>America's Pursuit of Precision Bombing,1910-1945</i> . Stephen L. McFarland. Smithsonian Institution Press, Washington, DC, 1995. xx, 312 pp., illus. $29.95. Smithsonian History of Aviation Series.