Pulmonary Function In Patients Research Articles

Longitudinal follow-up Study of the Intrarenal Hemodynamics and Pulmonary Function in Patients with T2DM

Longitudinal follow-up Study of the Intrarenal Hemodynamics and Pulmonary Function in Patients with T2DM

Longitudinal follow-up Study of the Intrarenal Hemodynamics and Pulmonary Function in Patients with T2DM

Longitudinal follow-up Study of the Intrarenal Hemodynamics and Pulmonary Function in Patients with T2DM

Impact of functional endoscopic sinus surgery for cases with nasal polypi on pulmonary function tests

Background: The upper and lower airways form one contiguous and functionally related organ, and are frequently exposed to similar inflammatory stimuli. There is increasing interest in the possibility that disease processes in one part of the airway may be reflected or manifest in another, thereby providing opportunities for dual diagnosis and therapy. Aim of this work: is to study the effect of removal of nasal polypi by functional endoscopic sinus surgery on pulmonary function tests. Patients and methods: This prospective study was carried out at Al-Azhar University hospitals (Al-Hussein and Bab El-Shaaria) in the period between December 2018 to December 2019 on 30 patients attended to outpatient clinics of ENT department to assess the effect of FESS on pulmonary functions of patients with a chronic rhinosinusitis with nasal polyposis without any other lung diseases. Results: In the present study, we noted a significant improvement in mean FVC by (0.25 L =7.6 %) one month post operatively and by (0.43 L=13 % ) three months post operatively. Also, there is a significant improvement in mean FEV1 by (0.59 L=27.6%) one month post operatively and by (0.92 L =43.2%) three months post operatively. Also, there is a significant improvement in mean FEV1/FVC % ratio by (19.3%) one month post operatively and by (28.3%) three months post operatively. Conclusion: This prospective randomized study showed that FESS have a positive effect on the pulmonary function of patients with chronic sinusitis with nasal polypi.

Pulmonary functions of patients with isolated mandibular fractures: a preliminary report.

ObjectivesThe aim of this study was to evaluate pulmonary function in patients with mandibular fractures and to determine the pattern of pulmonary functions in these patients.Materials and MethodsThis was a cross-sectional study of pulmonary functions in Nigerian non-smoking patients with isolated mandibular fractures managed at our health institution from December 2015 to June 2017. Forced vital capacity (FVC), forced expiratory volume in one second (FEV1), peak expiratory flow rate (PEFR), and ratio of FEV1 to FVC (FEV1/FVC) were measured for all participants using a portable spirometer just before treatment. The pulmonary indices were compared with the predicted reference values for Nigerians to determine the respiratory pattern.ResultsForty participants consisting of six females (15.0%) and thirty-four males (85.0%) with a female to male ratio of 1:5.7 were included in this study. The mean patient age was 34.5±13.1 years (range, 17–63 years). The mean FVC, FEV1, FEV1/FVC, and PEFR were 3.8±1.2 L, 3.0±1.0 L, 74.3%±13.8%, and 5.2±2.2 L/s, respectively. Comparison of data with predicted values revealed that 17 subjects (42.5%) had normal pulmonary function pattern while 23 subjects (57.5%) had features suggestive of obstructive and restrictive pulmonary function patterns.ConclusionIsolated mandibular fractures presented with abnormal pulmonary function pattern.

Impact of scoliosis surgery on pulmonary function in patients with muscular dystrophies and spinal muscular atrophy.

Scoliosis is a common complication of severe neuromuscular diseases. The aim of this study is to determine the impact of posterior spinal fusion on pulmonary function parameters in patients with severe neuromuscular disease at our medical center. Retrospective chart review of all patients with severe neuromuscular disease who had posterior spinal fusion between 2012 and 2017 at Texas Children's Hospital. Patients with growing rods, brain injury or malformation, and/or spina bifida were excluded. Pulmonary function measures before and after spinal surgery were determined. A total of 20 eligible patients were identified, 7 with Duchenne muscular dystrophy, 6 with spinal muscular atrophy, 3 with merosin deficient muscular dystrophy, 2 with Charcot-Marie-Tooth, 1 with central core disease, and 1 with dystroglycanopathy. The mean change in vital capacity from pre- to postspine surgery was a loss of 0.63 L for the spinal muscular atrophy patients, a loss of 0.36 L for the Duchenne muscular dystrophy patients, and a gain of 0.23 L for the merosin deficient patients. The difference between spinal muscular atrophy and merosin deficient patients was statistically significant (P = .02) CONCLUSION: In this single-center retrospective study, we found that after spine surgery for scoliosis, all patients with spinal muscular atrophy and most patients with Duchenne muscular dystrophy lost vital capacity, while the patients with merosin deficient muscular dystrophy gained vital capacity. These differences were not associated with differences is respiratory strength, body mass index, or surgical outcomes.

Endothelial Dysfunction in Patients having Asthma with Diabetes Mellitus Type 2 and Obesity

Profibrotic mediators and endothelial dysfunction markers may impact pulmonary function in patients having uncontrolled moderate asthma (As). 118 As patients were divided into 3 groups: Group I - isolated As (n=25); Group II As combined with diabetes mellitus type 2 (As+DM2); and Group III included As with obesity (As+Ob) (n=50). All subjects had fasting blood glucose level, insulin levels and HOMA-IR index, content of matrix metalloproteinase 9 (MMP-9), monocyte chemoattractant protein (MCP) and endothelin-1 (ET-1) assessed as well as anthropometric data and respiratory function (RF) obtained. Group I has As for 15.0 [14.0; 21.0] years; Group II had As for 22.0 [19.5; 28.0] years; and Group III has As 17.0 [15.0; 20.0] years. Group III mostly in poorly compensated carbohydrate metabolism. FEV1 was: Group I – 62.0 [41.5; 68.3]%; Group II – 53.0 [46.2; 69.0]%; and Group III – 56.0 [43.5; 68.3]%, with the normal – 95.0 [94.5; 95.0]%. All Groups showed relationships between MCP-1 and MMP-9: r1=0.5 (p=0.01), r2=0.29 (p=0.01),r3=0.86 (p=0.001); VWF: r1=0.49 (p=0.01), r2=0.28 (p=0.02), r3=0.58 (p=0.001); and ЕТ-1: r1=0.63 (p=0.001),r2=0.57 (p=0.001), r3 =0.59 (p=0.001). Central in the formation of fibrotic changes in uncontrolled moderate asthma are metabolic disturbances in extracellular matrix components, including collagen, impacted by MMP-9, MCP and ET-1 leading to endothelial dysfunction.

Effects of inverse ratio ventilation combined with lung protective ventilation on pulmonary function in patients with severe burns for surgery

ABSTRACT Objective To investigate the effects of inverse ratio ventilation combined with lung-protective ventilation on pulmonary function and inflammatory factors in severe burn patients undergoing surgery. Populations and Methods: Eighty patients with severe burns undergoing elective surgery were divided randomly into two groups: control (CG, n = 40) and experiment (EG, n = 40). The CG had conventional ventilation, whereas the EG were ventilated with tidal volume (TV) of 6–8 ml/kg, I (inspiration): E (expiration) of 2:1, and positive end-expiratory pressure (PEEP) 5 cm H2O. The following variables were evaluated before (T0), 1 h after start of surgery (T1) and after surgery (T2): oxygenation index (OI), partial pressure of carbon dioxide (PaCO2), TV, peak airway pressure (Ppeak), mean airway pressure (Pmean), PEEP, pulmonary dynamic compliance (Cdyn), alveolar–arterial difference of oxygen partial pressure D(A-a)O2, lactic acid (Lac), interleukin (IL)-6 and IL-10, and lung complications. Results: At T1 and T2 time points, the OI, Pmean and Cdyn were significantly greater in the EG than in the CG while the TV, Ppeak, D(A-a)O2, IL-6 and IL-10 were significantly smaller in the EG than in the CG. At the end of the surgery, the Lac was significantly smaller in the EG than in the CG (1.28 ± 0.19 vs. 1.40 ± 0.23 mmol/L). Twenty-four hours after the surgery, significantly more patients had hypoxemia (27.5 vs. 10.0%), increased expectoration (45.0 vs. 22.5%), increased lung texture or exudation (37.5 vs. 17.5%) in the CG than in the EG. Conclusions: Inverse ratio ventilation combined with lung-protective ventilation can reduce Ppeak, increase Pmean and Cdyn, improve the pulmonary oxygenation function, and decrease ILs in severe burn surgery patients.

Effects of Dexmedetomidine Combined with Remifentanil Anesthesia and Propofol Combined with Remifentanil Anesthesia on Perioperative Inflammatory Response and Pulmonary Function in Patients with Lung Cancer

To explore the effects of dexmedetomidine combined with remifentanil anesthesia and propofol combined with remifentanil anesthesia on perioperative inflammatory response and pulmonary function in patients with lung cancer... | Find, read and cite all the research you need on Tech Science Press

Albuterol combined with tiotropium bromide to improve the conditions and pulmonary functions of patients with acute exacerbation of chronic obstructive pulmonary disease

We aimed to explore the clinical efficacy and effects of albuterol combined with tiotropium bromide on pulmonary functions of patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). 72 patients with AECOPD were divided into a combination treatment group (n = 38, albuterol + tiotropium bromide) and the control group (n = 34, routine treatment). Efficacy, incidence of adverse reactions, results of blood gas analysis, pulmonary function indices, time to improve clinical symptoms, St. George's respiratory questionnaire (SGRQ), and British Medical Research Council (MMRC) scores were compared between the two groups. The overall response rate was significantly higher, and the time to improve coughing was significantly shorter, in the combination treatment group compared with controls (p < 0.05). After treatment, both groups achieved a marked rise in PaO2, forced expiratory volume in 1 s (FEV1), FEV1/forced vital capacity (FVC) ratio, and peak expiratory flow (PEF) (p < 0.05), which was more dominant with combination therapy. The reduction in PaCO2 was more obvious in the combination therapy group. The combination of albuterol and tiotropium bromide is an effective treatment for patients with AECOPD and functions by improving conditions and pulmonary functions without raising the incidence of adverse reactions.

Biomedical system to evaluate pulmonary function in patients with post-stroke hemiparesis

Abstract Introduction: Stroke is a neurological disorder considered the second major cause of death worldwide, leading to severe respiratory dysfunctions, evident in reduced respiratory muscle strength and the presence of muscle imbalances that directly affect the pulmonary mechanics of these patients. Objective: Evaluate the possible metric properties of a biomedical system, the IBI. Method: the study was conducted with 25 hemiparetic stroke patients of both sexes, using a manovacuometer, peak flow, and SG IBI for respiratory measurements. Results: Moderate to strong correlations were observed between the IBI biomedical system and peak flow and manovacuometer measurements, which were smaller than the predicted values. Conclusion: The results suggest that the IBI biomedical system is potentially valid for pulmonary function measurement, sensitive to air flow variations and generates maximum respiratory pressure. As such, it is an important resource for prescribing intensity and controlling progression in pulmonary rehabilitation.

Effect of parathyroid hormone levels on the functional capacity and pulmonary function of patients on dialysis

Abstract Introduction: Chronic kidney disease is characterized as the gradual loss of kidney function, with patients on dialysis experiencing a decline in functional capacity and pulmonary function. One of the non-traditional risk factors is parathyroid hormone (PTH), which influences metabolism and the status of the disease. Objective: Assess the effect of parathyroid hormone levels on functional capacity and pulmonary function in patients on dialysis. Method: Cross-sectional study with hemodynamically stable dialysis patients of both sexes, aged 18 to 59 years, who did not gain more than 2.5kg between dialysis sessions. Two groups were created according to PTH blood levels: PTH (A), with values outside the normal range, and PTH (C), who exhibited normal levels of the hormone. Pulmonary function (PF) was assessed by spirometry and functional capacity (FC) via the six-minute walk test (6MWT). Results: The PTH A group displayed a negative association between PTH levels and PF, based on the values obtained for the spirometric variables forced expiratory volume in 1 second (FEV1) (r = -0.54) and forced vital capacity (FVC) (r= -0.69). The average distance walked by the PTH (C) group was 343.85 ± 98.14 meters. Conclusion: The results suggest that high PTH levels have a negative effect on the PF of patients on dialysis.

Analysis of high-resolution computed tomography phenotypes and pulmonary function in chronic obstructive pulmonary disease

ObjectiveTo explore the correlation between high-resolution computed tomography (HRCT) phenotype and pulmonary function in patients with chronic obstructive pulmonary disease (COPD).MethodsFifty-six patients with COPD were retrospectively evaluated using pulmonary function tests (PFTs) and HRCT, and phenotypic pulmonary function parameters were analyzed.ResultsThirty-one patients were classified as having imaging phenotype A, 11 were phenotype E, and 14 were phenotype M. The total lung capacity (TLC)% of phenotype E was significantly higher than that of phenotypes A and M. The residual volume (RV) to TLC ratio (RV/TLC) in phenotype A was significantly lower than that in phenotypes E and M. The forced expiratory volume in one second percentage (FEV1%) and FEV1/forced vital capacity (FVC) of phenotype A was significantly higher than that of phenotypes E and M.ConclusionFEV1/FVC and FEV1% were higher and RV/TLC was lower, indicating less severe emphysema, in patients with phenotype A compared with patients with phenotypes E and M. TLC% of patients with phenotype E was significantly higher than that of patients with phenotypes A and M. The degree of airflow limitation was most severe in patients with phenotype M.

Is FEV1 associated with quality of life in children with cystic fibrosis? An original article

Introduction: Cystic fibrosis (CF) is a serious genetic life-shortening disease. Quality of life (QoL) measurement related to CF children is a relatively new field of research, which includes the patient’s perspective in research and clinical practice. Objectives: This study aimed to evaluate the QoL in children with CF and its association with FEV1 (forced expiratory volume in 1 second). Patients and Methods: This cross-sectional study was carried out on 7-14 years old children with CF attending children’s medical center from March 2017 to March 2018. Throat swab cultures and spirometry evaluation was performed for all patients. FEV1 was determined and the 6-min walk test (6MWT) was conducted. The patient’s psychological status was assessed using the Persian version of pediatric QoL inventory. ANOVA, t test, and chisquare tests were used for data analysis. Results: Seventy-six subjects with the mean age of 10.49±3.18 years were studied since 59% of them (n=44) were boys. The mean total QoL was 65.34±17.73. Patients with lower pulmonary function had a lower QoL. There was a significant association between FEV1 and school and emotional functioning (P=0.005 and P=0.002, respectively). A significant association was found between SPO2 (peripheral capillary oxygen saturation) reduction after 6MWT and FEV1 decline (P=0.001). Additionally, a significant association was detected between FEV1 and the distance walked during 6MWT (P=0.030). Conclusion: Regarding the association between pulmonary function and QoL in CF patients and lower QoL score in our study, the importance of assessing pulmonary function in these patients should not be neglected.

Effect of radiological extent and severity of bronchiectasis on pulmonary function

Background: The aim of this study was to ascertain the effect of the extent and severity of bronchiectasis as determined with high-resolution computed tomography (HRCT) on lung function in patients with pure bronchiectasis, bronchiectasis and asthma, and bronchiectasis and chronic obstructive pulmonary disease (COPD).&#x0D; Methods: One hundred nineteen patients (71 with pure bronchiectasis, 25 asthmatic patients with bronchiectasis, and 23 COPD patients with bronchiectasis) underwent HRCT and pulmonary function tests. Computed tomography features were scored by the consensus of 2 radiologists.&#x0D; Results: There were no statistically significant differences among the 3 patient groups regarding the extent of bronchiectasis, bronchial dilatation degree, bronchial wall thickening, decreased attenuation in the lung parenchyma, or presence of mucus in the large and small airways. In the pure bronchiectasis group, a negative correlation was found between forced vital capacity (FVC) % of predicted, forced expiratory volume in 1 sec (FEV1) % of predicted, the FEV1/FVC ratio and the extent of bronchiectasis, bronchial wall thickening, bronchial wall dilatation, and decreased attenuation. At multivariate analysis the main morphologic changes associated with impairment of FVC and FEV1 were the extent of bronchiectasis and a decreased attenuation in the lung parenchyma. The decrease in the FEV1/FVC ratio was associated with bronchial wall dilatation. No correlation was found between morphologic changes and indices of pulmonary function in the asthma and COPD patients.&#x0D; Conclusions: Morphologic changes associated with bronchiectasis do not influence lung function in patients with asthma and COPD directly, although they do play a role in impairing pulmonary function in patients with bronchiectasis alone.

The Effects of Thoracic Joint Mobilization on Pulmonary Functions of Patients With Stroke

The Effects of Thoracic Joint Mobilization on Pulmonary Functions of Patients With Stroke

Diabetic pneumopathy: A study of induced sputum and pulmonary function in patients with type 2 diabetes mellitus

Objective: To evaluate the cellularity, and albumin and interleukin(IL)-1 levels in induced sputum (IS), and to determinerespiratory function parameters in patients with type 2 diabetesmellitus (DM2). Design: A cross-section study in type 2diabetes mellitus. Participants: Patients with type 2 diabetesmellitus and healthy people. Methods: Patients in both groupshad normal chest x-ray findings. Exclusion criteria for bothgroups were: the presence of current pulmonary disease orsequelae, smoking, respiratory atopy, or respiratory infectionin the past 3 months. The study consisted of two sub-studies.In sub-study 1 (SS1), measurements of pulmonary volume andflow, and diffusion capacity for carbon monoxide (DLCO) wereperformed. In sub-study 2 (SS2), analysis of cellularity, albumin,and IL-1 in IS was performed. Results: In all, 60 patients(45 women, 75%) with DM2 with a mean age of 59.52 years (SD,9.03) were included in SS1. The DM2 group included 8 patientswith airway obstruction (13.33%) without reversibility withbronchodilators, and 9 with restrictive disease (15.00 %) (p =0.026). The DLCO was reduced in 17 patients (28.33%) in theDM2 group. In the control group, all individuals had valueswithin the reference intervals. Lymphocytosis was found inthe IS of patients with DM2 (p = 0.028). The levels of sputumalbumin showed no statistical difference between the twogroups. Conclusion: Our findings indicate the presence ofpulmonary impairment in DM2, characterized by changes inthe respiratory function and a lymphocytosis in IS.Keywords: Diabetes mellitus type 2; Induced sputum;Lymphocytes.

Editorial

Dear AllThe broad approach of the Brazilian Journal ofHealth and Biomedical Sciences shows itself again inthis issue. The papers are related to a variety of subjectscovering different populations. The current issuecontains a diversity of interesting and important studiesthat use practical and convenient techniques involvingboth young and elderly groups. This stimulatesthe reader to be in contact with a range of possibleinformation in the health and biomedical sciences areathat is highly relevant and current worldwide.In addition, several conditions related todiseases, such as type 2 diabetes mellitus (T2DM),chronic obstructive pulmonary disease (COPD), kneeosteoarthritis (KOA), and frailty are presented inthe studies. Findings are presented from the clinicalevaluation of induced sputum and pulmonary functionin patients with T2DM, racial/ethnic differences inbone mineral density, muscle function and fat mass inyoung women, land-based versus water-based walkingprograms in elderly women with KOA, processing speedduring attention and memory tasks as an indicator offrailty, use of the 6-minute walking test to evaluatepatients with respiratory disease, as well as an evaluationof the prevalence of sickle cell trait in blood donorsthrough a systematic review. An epidemiologicalanalysis of exogenous poisoning is also presented.The objectives of the papers published in thisissue include: (i) systematizing data related to theprevalence of sickle cell trait among blood donors;(ii) determination of racial/ethnic differences in bonemineral density, muscle function and fat mass inwomen of Caucasian, East-Asian, South-Asian, Hispanicand African-American backgrounds; (iii) investigationof effects of a walking program with a controlledprogressive workload in water compared to land withregard to pain, functional and physical performance,and quality of life in elderly women with KOA; (iv)characterization of the processing speed duringattention and memory tasks in a geriatric populationin different states of frailty in order to verify thefactors that most contribute to the frailty phenotype;(v) comparative cross-sectional study of the 6-minutewalking test data with inclusion of individuals withsystemic sclerosis, idiopathic pulmonary fibrosis andCOPD; (vi) evaluation of cellularity, albumin andinterleukin-1 levels in induced sputum to determinerespiratory function parameters in patients withT2DM; and (vii) observation of patterns in cases ofexogenous poisoning in a region of the State of MinasGerais, Brazil.Readers of the BJHBS may expect to access relevantdiscussions of subjects in Health and BiomedicalSciences.

Changes in Pulmonary Function in Patients With Advanced Heart Failure Listed for Heart Transplantation

BackgroundPulmonary function tests (PFTs) are often impaired in patients with advanced heart failure. There is limited data about their impact on survival after heart transplantation (HT). We sought to assess the prevalence and type of PFT abnormalities in patients on HT waiting list and their impact on outcomes. MethodsWe performed a retrospective analysis of a prospective registry of consecutive patients undergoing HT between 2012 and 2018. Patients were classified into 4 groups according to pre-HT PFT results: 1. normal pattern: forced vital capacity (FVC) ≥ 80% and forced expiratory volume in 1 second (FEV1) to FVC ratio (FEV1/FVC) ≥ 0.7; 2. obstructive: FEV1/FVC < 0.7; 3. nonobstructive: FEV1/FVC ≥ 0.7 and FVC < 80% when total lung capacity value was not available; and 4. restrictive: FEV1/FVC ≥ 0.7 and total lung capacity < 80%. The prevalence of impaired carbon monoxide diffusing capacity corrected for hemoglobin < 80% and FEV1 < 70% was also analyzed. High-urgency HT patients and those referred from other centers without quantitative pulmonary evaluation were excluded. ResultsAmong 123 patients who underwent HT, 83 patients with complete PFT were included. Median follow-up was 2.7 ± 1.9 years. Of these, 29 (34.9%) had an obstructive pattern, 20 (24.1%) a nonobstructive, 18 (21.7%) a restrictive, and 16 (19.3%) a normal pattern. Fifty-one (61.4%) patients had FEV1 < 70% and 58 (69.9%) a carbon monoxide diffusing capacity corrected for hemoglobin < 80%. There was a tendency to lower survival in all altered PFT groups compared with normal (P = .054) but not within the other groups. Patients with an impaired FEV1 had significantly higher mortality than patients with normal values (P = .008). Area under receiver operating characteristic curve for FEV1 was 0.73 (95% confidence interval [0.60-0.86]). A cutoff value of FEV1 (60.5) predicts mortality with 66% sensitivity and 64% specificity. ConclusionsPFT alterations have a very high prevalence on HT waiting list patients. Patients with impaired FEV1 had worse outcomes after heart transplantation.

Influence of Emphysema and Air Trapping Heterogeneity on Pulmonary Function in Patients with COPD.

PurposeTo explore the influence of emphysema and air trapping heterogeneity on pulmonary function changes in patients with stable chronic obstructive pulmonary disease (COPD).Patients and methodsOne hundred and seventy-nine patients with stable COPD were enrolled in this prospective study. All patients underwent low-dose inspiratory and expiratory CT scanning and pulmonary-function tests. CT quantitative data for the emphysema index (EI) on full-inspiration and air trapping (AT) on full-expiration were measured for the whole lung, the right and left lungs, and the cranial-caudal lung zones. The heterogeneity index (HI) values for emphysema and air trapping were determined as the ratio of the difference to the sum of the respective indexes. The cranial-caudal HI and left–right lung HI were compared between mild-to-moderate (GOLD stage I and II) and severe (GOLD stage III and IV) disease groups. The associations between HI and pulmonary-function measurements adjusted for age, sex, height, smoking history, EI and AT of the total lung were assessed using multiple linear regression analysis.ResultsThe absolute values for cranial-caudal HI (AT_CC_HI) and left–right lung HI (AT_LR_HI) on full-expiration were significantly larger in the mild-to-moderate group, while no significant intergroup differences were observed on full-inspiration. COPD patients with lower-zone and/or left-lung predominance showed significantly lower pulmonary function than those with upper-zone and/or right-lung predominance on full-expiration, whereas no significant differences were observed on full-inspiration. The absolute values of AT_CC_HI and AT_LR_HI significantly correlated with pulmonary-function measurements. Higher AT_CC_HI and lower AT_LR_HI absolute values indicated better pulmonary function, after adjusting for age, sex, height, smoking history, EI and AT of the total lung.ConclusionSubjects with more heterogeneous distribution and/or upper-zone predominant and/or right-lung predominant patterns on full-expiration tend to have better pulmonary function. Thus, in comparison with emphysema heterogeneity, AT heterogeneity better reflects the pulmonary function changes in COPD patients.

Valores de referencia de la Global Lung Function Iniciative 2012 en un grupo de pacientes pediátricos asmáticos alérgicos

Resumen&#x0D; Propósito En 2012 Quanjer et.al. presentaron las ecuaciones globales de función pulmonar en pacientes entre 3 y 95 años. El objetivo del trabajo es conocer si el comportamiento espirométrico de pacientes con asma alérgico utilizando las tablas del Global Lung Function Iniciative 2012 -GLI son similares a los valores espirométricos de Hsu HK et.al. utilizada en nuestro laboratorio de función pulmonar para el diagnóstico.&#x0D; Material y Método Estudio descriptivo de tipo serie de casos, en pacientes con asma alérgico diagnosticados en el año 2018 y 2019; que cumplieron con los criterios de inclusión.&#x0D; Resultados Tres pacientes dieron valores de puntaje z para el VEF1 por debajo del límite inferior para normalidad y 6 pacientes dieron valores de puntaje z por debajo del límite inferior de la normalidad para la relación del VEF1/CVF. Comparado, con los valores de función pulmonar usados en nuestra unidad, que son los descritos por Hsu KH, et.al los resultaros fueron similares en ambas escalas obteniendo el mismo número de pacientes con patrones de obstrucción. Solo se encontró asociación positiva entre el nivel de la IgE y el valor del VEF1 (p=0.01) y entre el nivel de la IgE y el puntaje z para VEF1 (p=0.03).&#x0D; Conclusiones Los valores predictivos espirométricos de Hsu et.al se comportan similarmente a los de la Global Lung Function Iniciative, por lo que consideramos que cualquier de las dos tablas de valores son aplicables a nuestra población.