Psychophysiological Stress Response Research Articles

Childhood trauma and resilience in psoriatic patients: A preliminary report

AimsPsoriasis is a chronic inflammatory skin disease with a complex etiology, involving the immune system, genetic factors, and external/internal triggers, with psychosomatic aspects. The aim of the study was to investigate childhood trauma and resilience in a psoriatic sample compared with healthy controls. Correlations between childhood trauma, resilience, quality of life, clinical data and psoriatic features were also evaluated. MethodsSeventy-seven psoriatic patients and seventy-six homogeneous healthy controls were enrolled. We used the Psoriasis Area and Severity Index (PASI) to assess the severity of psoriasis and the Skindex-29 to measure health-related quality of life. The psychometric battery included the Childhood Trauma Questionnaire (CTQ) and the Connor-Davidson Resilience Scale (CD-Risc) to assess trauma exposure and resilience, respectively. ResultsPsoriatic patients showed a significant prevalence of childhood trauma and a lower resilience level compared to healthy controls. Associations between traumatic experiences, low resilience and reduced quality of life in psoriatic subjects were also observed. ConclusionsA multidisciplinary approach is helpful to investigate clinical aspects, trigger factors and psychophysiological stress response in psoriatic subjects. Improving resilience with an early psychological intervention focused on self-motivation and strengthening of self-efficacy could facilitate the management of psoriasis.

The impact of pre-existing anxiety on affective and cognitive processing of a Virtual Reality analogue trauma.

Dysfunctional processing of traumatic events may be in particular related to high trait anxiety as a pre-traumatic risk factor for the development of post-traumatic stress disorder (PTSD). However, as this has rarely been investigated in prospective, experimental studies, we aimed to analyse the association between high trait anxiety and affective as well as cognitive processing of stress using a new prospective Virtual Reality analogue trauma paradigm to overcome limitations of retrospective or current analogue designs. Individuals with high and low trait anxiety (N = 80) were exposed to a multi-sensory Virtual Reality emergency scenario while psychophysiological stress response, emotion regulation and intrusive memories were assessed. Our results showed that high trait anxiety individuals display increased (i) subjective stress responses, (ii) emotion dysregulation and (iii) intrusive memories upon VR analogue trauma exposure. In particular, our sample of high trait anxiety individuals displayed limited access to different emotion regulation strategies as well as increased worry and rumination regarding perceived intrusive memories. Considering the complex interplay of multiple risk factors, our findings suggests that peri-traumatic affective processing seems to mediate high trait anxiety and post-traumatic intrusive memories thereby pointing out the central role of peri-traumatic processes for intrusion development. In addition, HA as a modulating pre-traumatic risk factor might further increase the risk of later dysfunctional processing of an analogue trauma by interacting with factors of affective processing during analogue trauma exposure. Implications of these findings which may contribute to a higher risk to develop PTSD are discussed.

心身症患者におけるPsychophysiological Stress Responseの特徴

心身症患者におけるPsychophysiological Stress Responseの特徴

Psychophysiological response in parachute jumps, the effect of experience and type of jump

We aimed to analyse the effect of experience and type of parachute jump on the psychophysiological responses of jumpers. We analysed blood oxygen saturation, heart rate, blood glucose, lactate and creatinkinase, leg strength, isometric hand strength, cortical arousal, specific fine motor skills, self-confidence and cognition, and somatic and state anxiety, before and after four different parachute jumps: a sport parachute jump, a manual tactical parachute jump, tandem pilots, and tandem passengers. Independently of the parachute jump, the psychophysiological responses of experienced paratroopers were not affected by the jumps, except for an increase in anaerobic metabolism. Novice parachute jumpers presented a higher psychophysiological stress response than the experienced jumpers, together with a large anticipatory anxiety response before the jump; however, this decreased after the jump, although the high physiological activation was maintained. This information could be used by civil and military paratroopers' instructors to improve their training programmes.

The effects of goal priming on cortisol responses in an ego-involving climate

ObjectivesThis study examined the potential for a motivational priming session to buffer the psychophysiological stress response to an ego-involving climate in a physical activity setting. Research in Achievement Goal Perspective Theory (AGPT) suggests that creating a caring/task-involving climate can have beneficial effects on participants in physical activity settings, even buffering the physiological response to stress. However, less is known about how individuals might buffer that response when an ego-involving climate is occurring beyond their control. DesignMale college students (N = 38) between the ages of 18 and 30 years (Mage=20.68,SD=2.66) were randomly assigned to either a control group with no exposure to AGPT or an experimental (i.e., AGPT motivational priming) group, and took part in an ego-involving juggling session. Psychophysiological stress responses (e.g., cortisol) were assessed. MethodPrior to juggling, the experimental group received a motivational priming session that briefly reviewed the body of AGPT literature, while the control group received information on the history of Sport Psychology as a professional field. Cortisol was measured at five time points throughout the study via saliva samples. Participants also completed pre- and post-measures of self-reported anxiety and self-confidence (CSAI-2). ResultsResults showed a marked increase in cortisol (as measured by percent change from baseline) in the control group, but not the experimental group. Psychological responses were stable across groups. ConclusionProviding athletes and exercisers with nothing more than basic information on AGPT can reduce their physiological markers of psychosocial stress in ego-involving climates. Such education may be a beneficial practice for coaches, physical educators, and trainers.

Effects of Combined Foot Massage and Cognitive Behavioral Therapy on the Stress Response in Middle-Aged Women.

Several intervention studies have suggested that foot massage and cognitive behavioral therapy (CBT) are beneficial for reducing the stress response. However, no randomized control trials have been conducted to examine these effects in middle-aged women, who are more commonly exposed to stress relative to others. This study aimed to examine the effects of combined self-administered foot massage and CBT on the psychophysiological stress response in Korean middle-aged women. Randomized controlled trial. Subjects were recruited from the social welfare center in Sahmcheok, Kangwondo, Korea. The subjects performed some of the massage at the center and some at home, and CBT was performed at the center. Fifty-three women aged 45-64 years were randomly assigned to Group A (intervention, n = 31) or B (usual care, n = 30). Combined self-administered foot massage and CBT. Depression, anxiety, stress, blood pressure, heart rate, blood glucose (BG), and oxygen saturation were measured at baseline and 3-week follow-up. Mean depression scores (p = 0.021), stress scores (p = 0.009), systolic blood pressure (SBP) (p = 0.035), and BG levels (p = 0.007) had decreased significantly subsequent to the intervention. Combined self-administered foot massage and CBT led to reductions in depression, stress, SBP, and BG levels. Therefore, the intervention could be an effective means of reducing the stress response in middle-aged women.

Searching for a job: Cardiac responses to acute stress and the mediating role of threat appraisal in young people.

Being unemployed and looking for a job has become a source of stress for many people in several European countries. However, little attention has been paid to the impact of this stressful situation on the individuals' psychophysiological stress responses. The aim of this study was to investigate the effect of being an unemployed job seeker on cognitive threat appraisal and cardiac responses to a psychosocial stressor. We exposed a group of unemployed job seekers (N=42) and a matched group of unemployed non-job seekers (N=40) to a standardized social stressor in form of job interview, the Trier Social Stress Test. Our results showed that unemployed job seekers manifest lower cardiac responses, along with a lower cognitive threat appraisal, compared to non-job seekers. Moreover, we observed a full mediating role of cognitive threat appraisal on the relationship between being an unemployed job seeker and cardiac responses to stress. These findings reveal that being unemployed and looking for a job has an effect on physiological responses to acute stress, as well as the importance of psychological process related to the situation. These responses might lead to negative health and motivational consequences. Theoretical and practical implications are discussed.

Effects of Video-Assisted Debriefing Compared with Standard Oral Debriefing

BackgroundVideo playback during debriefing is a frequent recommendation to develop skillful practice; however, research shows no clear benefit. MethodA randomized controlled trial was conducted to determine the effects of type of debriefing on psychophysiological stress responses and performance of nursing students in a repeated simulation after approximately two weeks. ResultsCompared with oral debriefing, video-assisted debriefing had no significant effect on the psychophysiological stress responses and performance. Across sessions, state anxiety significantly decreased and performance score improved. ConclusionReduced psychological stress and improved performance found in the repeat exposure validate the usefulness of simulation-based education to foster practice-based learning.

Negative affect, perceived health, and endocrine and immunological levels in caregivers of offspring with schizophrenia.

Negative affect (NA) and chronic stress are separately associated with health imbalances, and the interaction between the two aspects remains unclear. Care of relatives with long-term pathologies could be a likely model in the study of this issue, as caregivers frequently report chronic stress and health complaints. The aim of this study is examine the role of NA on psychophysiological stress-induced response and health in schizophrenia caregivers. Forty-one caregivers were distributed into two groups accordingly to their scores in NA. Thirteen non-caregivers were included as a control group. Participants were exposed to a repeated acute psychosocial stress while salivary cortisol, immunoglobulin A (IgA), and skin conductance level (SCL) were measured before, during, and after stress. Mood, state-anxiety, care conditions and perceived general health were also assessed. Caregivers with higher NA reported negative perceptions, worse health, and greater decreases in cortisol and IgA response than caregivers with low NA and than non-caregivers. NA could reduce the capability to develop adaptive psychophysiological stress responses. From a preventive view, the evaluation of NA could be useful to detect and assist high-risk individuals in potentially chronically stressed populations.

Efectos diferenciales de la atención y la claridad emocional sobre la percepción de estresores académicos y las respuestas de estrés de estudiantes de fisioterapia

ObjectiveTo analyze the differential effects of levels of emotional attention and emotional clarity on the perception of academic stressors and stress responses of physiotherapy students. Material and methodLevels of emotional attention and emotional clarity were measured with Difficulties in Emotional Regulation Scale, and perception of academic stressors and stress responses were evaluated with Academic Stress Questionnaire in 500 physiotherapy students from different Spanish universities. Students were classified according to their degree of emotional attention and emotional clarity in high, medium and low, and the perception of stressors and stress responses were compared through analysis of variance. ResultsStudents with high emotional clarity assess the academic environment as less threatening and show lower psychophysiological stress responses in comparison to students with medium or low levels of emotional clarity. Conversely, students with low emotional attention only assess more stressful situations related to beliefs about the performance and the value of content than students with high emotional attention. ConclusionsWhile emotional clarity has a moderating role on the valuation of the academic environment as threatening and on the physical and psychological effects of stress, the role of emotional attention is less relevant and only relates with the perception of stressors linked to the beliefs of the student.

How are neuroticism and depression related to the psychophysiological stress response to acute stress in healthy older people?

Neuroticism and depressive symptomatology have been related to a heightened and diminished physiological stress response, which may partly explain their negative relationship with health and wellbeing. Identifying factors that may increase disease vulnerability is especially relevant in older people, whose physiological systems decline. With this in mind, we investigated the influence of neuroticism and depression on the psychophysiological stress response in healthy older people (from 55 to 76years old). A total of 36 volunteers were exposed to a stressful task (Trier Social Stress Test, TSST), while 35 volunteers performed a control non-stressful task. The physiological stress response was assessed through measures of cortisol, alpha-amylase, heart rate (HR). Our results showed that, neuroticism was not related to physiological stress response. However, depression was related to higher cortisol response and lower HR reactivity in the stress condition. In summary, emotional states such as depressive mood seem to amplify the cortisol stress response and reduce the cardiovascular response, whereas more stable dispositions such as neuroticism did not affect stress response in older people. These findings confirm, in healthy older people, the adverse effects of depression, acting on different subsystems of the stress response.

Psychophysiological Stress Reactivity Relationships across the Menstrual Cycle.

While evidence suggests that women exhibit psychophysiological differences in stress reactivity across the menstrual cycle, the relationships among psychological and physiological stress reactivity states are not well understood. Healthy, normally cycling women (N = 44) participated in two counterbalanced laboratory sessions during the follicular and luteal phases where heart rate and subjective stress were assessed in response to stressors. There were no differences in the magnitudes of psychophysiological stress responses across the cycle. Psychological and physiological states were largely unrelated in the follicular phase but interrelationships were found in the luteal phase and these relationships were influenced by autonomic perception and trait anxiety. For women with high trait anxiety, autonomic perception appeared to buffer psychological and physiological stress reactivity during the luteal phase, suggesting that autonomic perception may be a protective factor for more anxious women during times of acute stress.

Immunity, inflammatory and psychophysiological stress response during a competition of professional rugby union

Abstract Neopterin, cortisol and immunoglobulin A were measured to determine what effect a professional rugby competition has on the immunity, inflammatory and psychophysiological stress response. Urine and saliva were collected from 37 professional players at regular intervals throughout a 20 week professional competition. Total neopterin, cortisol and secretory immunoglobulin A were analysed using enzyme linked immunosorbant assay (ELISA) and high performance liquid chromatography (HPLC). All markers did not change significantly when analysed as a group during the course of the season compared to baseline (p>0.05), although long-distance travel had a minor effect on cortisol and secretory immunoglobulin A concentrations (p<0.05). More importantly, a large inter-individual variation for all markers was observed (p<0.001). These results indicate this competition of professional rugby does not cause significant changes in psychophysiological stress. Some players however, may become more susceptible to fatigue and infection during the course of a season as a result of suppressed immunity and sustained activation of the inflammatory response.

Marital Quality Buffers the Association Between Socioeconomic Status and Ambulatory Blood Pressure.

Socioeconomic status is robustly associated with rates of death and disease. Psychophysiological stress processes are thought to account for a portion of this association. Although positive and supportive relationships can buffer psychophysiological stress responses, no studies have examined whether the quality of a primary adult relationship-marriage-may buffer the negative association between socioeconomic status and stress-related disease processes. The current study examines the interaction between income and marital quality (supportive vs. ambivalent) on individuals' daily ambulatory blood pressure, a valid and reliable indicator of cardiovascular risk. Results revealed that supportive marital relationships buffered the otherwise higher ambulatory diastolic blood pressure associated with low income. Results are consistent with the buffering hypothesis of social support and suggest that a supportive spouse may buffer stress-related autonomic processes linking low socioeconomic status to risk for cardiovascular disease.

Transdermal neuromodulation of noradrenergic activity suppresses psychophysiological and biochemical stress responses in humans.

We engineered a transdermal neuromodulation approach that targets peripheral (cranial and spinal) nerves and utilizes their afferent pathways as signaling conduits to influence brain function. We investigated the effects of this transdermal electrical neurosignaling (TEN) method on sympathetic physiology under different experimental conditions. The TEN method involved delivering high-frequency pulsed electrical currents to ophthalmic and maxillary divisions of the right trigeminal nerve and cervical spinal nerve afferents. Under resting conditions, TEN significantly suppressed basal sympathetic tone compared to sham as indicated by functional infrared thermography of facial temperatures. In a different experiment, subjects treated with TEN reported significantly lower levels of tension and anxiety on the Profile of Mood States scale compared to sham. In a third experiment when subjects were experimentally stressed TEN produced a significant suppression of heart rate variability, galvanic skin conductance, and salivary α-amylase levels compared to sham. Collectively these observations demonstrate TEN can dampen basal sympathetic tone and attenuate sympathetic activity in response to acute stress induction. Our physiological and biochemical observations are consistent with the hypothesis that TEN modulates noradrenergic signaling to suppress sympathetic activity. We conclude that dampening sympathetic activity in such a manner represents a promising approach to managing daily stress.

Stress in crisis managers: evidence from self-report and psychophysiological assessments.

Directing disaster operations represents a major professional challenge. Despite its importance to health and professional performance, research on stress in crisis management remains scarce. The present study aimed to investigate self-reported stress and psychophysiological stress responses in crisis managers. For this purpose, 30 crisis managers were compared with 30 managers from other disciplines, in terms of self-reported stress, health status and psychophysiological reactivity to crisis-related and non-specific visual and acoustic aversive stimuli and cognitive challenge. Crisis managers reported lower stress levels, a more positive strain-recuperation-balance, greater social resources, reduced physical symptoms, as well as more physical exercise and less alcohol consumption. They exhibited diminished electrodermal and heart rate responses to crisis-related and non-specific stressors. The results indicate reduced stress and physical complaints, diminished psychophysiological stress reactivity, and a healthier life-style in crisis managers. Improved stress resistance may limit vulnerability to stress-related performance decline and facilitate preparedness for major incidents.

A Preliminary Study on the Relationship Between Athletes' Ability to Self-Regulate and World Ranking

This study was designed to explore the relationship between elite athletes' self-regulation ability and their ranking at the world level using psychophysiological stress assessment profiling. Fifteen elite level athletes' psychophysiological stress response patterns were recorded during a nine-stage stress assessment. Respiration rate, heart rate, heart rate variability, skin conductance, peripheral body temperature, and electromyograph (trapezius and frontalis) were monitored. There was a significant correlation between elite athletes' overall self-regulation ability and their ranking at the world level, meaning that the better the overall self-regulation ability of the athlete, the better the world ranking. In addition, a multiple regression analysis indicated that self-regulation accounted for 76% of the variance in world ranking. Our results suggest the existence of a relationship between elite athletes' overall self-regulation ability and their ranking at the world level. Therefore, the results of this study have important implications for training of optimal psychophysiological self-regulation in athletes.

Affect-laden imagery and risk taking: the mediating role of stress and risk perception.

This paper investigates how affect-laden imagery that evokes emotional stress influences risk perception and risk taking in real-life scenarios. In a series of three studies, we instructed participants to imagine the consequences of risky scenarios and then rate the intensity of the experienced stress, perceived risk and their willingness to engage in risky behavior. Study 1 showed that people spontaneously imagine negative rather than positive risk consequences, which are directly related to their lower willingness to take risk. Moreover, this relationship was mediated by feelings of stress and risk perception. Study 2 replicated and extended these findings by showing that imagining negative risk consequences evokes psychophysiological stress responses observed in elevated blood pressure. Finally, in Study 3, we once again demonstrated that a higher intensity of mental images of negative risk consequences, as measured by enhanced brain activity in the parieto-occipital lobes, leads to a lower propensity to take risk. Furthermore, individual differences in creating vivid and intense negative images of risk consequences moderated the strength of the relationship between risk perception and risk taking. Participants who created more vivid and intense images of negative risk consequences paid less attention to the assessments of riskiness in rating their likelihood to take risk. To summarize, we showed that feelings of emotional stress and perceived riskiness mediate the relationship between mental imagery and risk taking, whereas individual differences in abilities to create vivid mental images may influence the degree to which more cognitive risk assessments are used in the risk-taking process.

Linguistic Methods to Detect Lies

The present manuscript mainly introduces three linguistic methods to detect lies, namely Hand-writing Analysis, Voice Stress Analysis, and Non-Verbal Analysis and the application of these linguistic deception detection approaches in various fields, such as law enforcement, intelligence agencies, and forensic context. These major deception detection techniques are illustrated by examples based on graphology, psycho-physiological stress response, and non-verbal communication studies.

Normalizing effect of heroin maintenance treatment on stress-induced brain connectivity.

Recent evidence has shown that a single maintenance dose of heroin attenuates psychophysiological stress responses in heroin-dependent patients, probably reflecting the effectiveness of heroin-assisted therapies for the treatment of severe heroin addiction. However, the underlying neural circuitry of these effects has not yet been investigated. Using a cross-over, double-blind, vehicle-controlled design, 22 heroin-dependent and heroin-maintained outpatients from the Centre of Substance Use Disorders at the University Hospital of Psychiatry in Basel were studied after heroin and placebo administration, while 17 healthy controls from the general population were included for placebo administration only. Functional magnetic resonance imaging was used to detect brain responses to fearful faces and dynamic causal modelling was applied to compute fear-induced modulation of connectivity within the emotional face network. Stress responses were assessed by hormone releases and subjective ratings. Relative to placebo, heroin acutely reduced the fear-induced modulation of connectivity from the left fusiform gyrus to the left amygdala and from the right amygdala to the right orbitofrontal cortex in dependent patients. Both of these amygdala-related connectivity strengths were significantly increased in patients after placebo treatment (acute withdrawal) compared to healthy controls, whose connectivity estimates did not differ from those of patients after heroin injection. Moreover, we found positive correlations between the left fusiform gyrus to amygdala connectivity and different stress responses, as well as between the right amygdala to orbitofrontal cortex connectivity and levels of craving. Our findings indicate that the increased amygdala-related connectivity during fearful face processing after the placebo treatment in heroin-dependent patients transiently normalizes after acute heroin maintenance treatment. Furthermore, this study suggests that the assessment of amygdala-related connectivity during fear processing may provide a prognostic tool to assess stress levels in heroin-dependent patients and to quantify the efficacy of maintenance treatments in drug addiction.