Psychophysiological Stress Response Research Articles

Effect of Experience and Professional Role on Psychophysiological Stress Response in an Underwater Evacuation Training

Background: This research aimed to analyze the effect of experience and professional role on psychophysiological stress response in underwater evacuation training. Methods: We analyzed 36 participants (39.06±9.01 years), divided into two different groups; 17 crew members (38.6±7.2 years) and 19 medical members (39.5±10.5 years). modifications in the rating of perceived exertion, subjective stress perception, heart rate, blood oxygen saturation, cortical arousal, heart rate variability, spirometry, isometric hand strength, and short-term memory before and after underwater evacuation training were analyzed. Results: The maneuver produced a significant increase in SSP, RPE, IHS, FVC, and SatO2 at different moments of the intervention, being higher in crew members. Conclusions: We found that the underwater evacuation training produced an anticipatory anxiety response, and an increase in autonomous sympathetic nervous system modulation not affecting strength capacities, cortical arousal, and memory independently of the aircraft role (medical or crew).

Effects of Military Equipment on the Psychophysiological Stress Response during a HIIT Workout

Background: Army operations produce various psychophysiological responses of military personnel. Traditionally, to prepare soldiers for these requirements, military workouts have been based on long-distance and low-intensity training. Recent researches suggest that high-intensity interval training (HIIT) may be more effective due to the characteristics of actual theaters of operation. there is a lack of research on the actual effects of military equipment in the context of combat or HIIT training. This study aimed to analyze the effects of military equipment on psychophysiological responses during a HIIT session. Methods: 20 soldiers of the Spanish Army (aged 27.3 ± 3.4 years; height 176.6 ± 4.7 m; weight 76.8 ± 7.4 kg) were evaluated after and before a traditional running HIIT which consisted of 12 repetitions of 30 seconds at maximum intensity, with a 30-second rest between exercises. Blood lactate, rate of perceived exertion and stress, upper and lower limbs, and respiratory muscle strength, skin temperature, blood oxygen saturation, heart rate, cortical arousal were measured before and after the training. Results: Results are reported with their mean and standard deviation. Significant differences were found in RPE, SSP, BOS, and Lactate in both groups in pre and post-training with the two outfits analyzed. Also, it was observed significant differences in HJ, UMS, and PEF values when the group was equipped with military equipment. Significant differences were found in RPE pre-training values and RPE, Stress perception, BOS, HR, and lactate post-training values. Conclusions: The use of military equipment during a high intensity interval training session produces higher stress perception and perceived exertion than the civil outfit. The mechanical difficulty and the lack of operability in movements could be a reason for this psychophysiological response.

Trait-dependent effects of theta burst stimulation after psychosocial stress: a sham-controlled study in healthy individuals

ObjectivePrevious studies suggest that theta burst stimulation (TBS), a form of repetitive transcranial magnetic stimulation (rTMS), applied to the left dorsolateral prefrontal cortex (DLPFC) might be a promising approach to modulate stress-reactive rumination and the associated psychophysiological stress response. Crucially, individuals showing higher levels of trait rumination might benefit more from prefrontal stimulation. MethodsIn this sham-controlled study, 127 healthy individuals, with varying ruminative tendencies, received a single-session of intermittent TBS (iTBS), continuous TBS (cTBS) or sham TBS (sTBS) over the left DLPFC before being confronted with a Trier Social Stress Test. ResultsResults showed significant TBS effects on salivary cortisol as a function of trait rumination. cTBS, as compared to sTBS and iTBS, resulted in an attenuated stress-induced cortisol response in high compared to low trait ruminators. Although independent of trait rumination levels, cTBS showed positive effects on stress-related changes in mood and, both cTBS and iTBS (versus sham) presented an enhanced heart rate recovery following the stressor. We found no evidence for (trait rumination-dependent) TBS effects on stress-reactive rumination, negative affect, subjective stress or heart rate variability. ConclusionscTBS shows beneficial effects on certain measures of stress, especially in high trait ruminators. SignificanceThese findings highlight the importance of accounting for individual differences when examining TBS effects.

Treatment Effects on Psychophysiological Stress Responses in Youth With Obesity.

Stress plays a central role in obesity development, but research on treatment options to tackle elevated stress levels in youth with obesity is scarce. The present study examined the impact of the Multidisciplinary Obesity Treatment (MOT; lifestyle intervention including physical exercise, healthy meals, and cognitive behavioral techniques) on physiological stress parameters in youth with obesity and assessed whether adding emotion regulation (ER) training on top of MOT is beneficial. From an inpatient treatment center for obesity, 92 youngsters (mean [standard deviation] age = 12.50 [1.66] years, 43.5% boys) were randomly assigned to a control group (MOT) or experimental group (MOT + ER training). Before (T1) and after 12 weeks of treatment (T2), high-frequency heart rate variability (HF-HRV) and heart rate were measured at rest and during a stress induction (= psychophysiological reactivity). At T2, after MOT only, participants displayed a lower resting heart rate ( MT2/T1 = 74.7/78.6) and a reduced stress response (i.e., less decrease in HF-HRV [ MT2/T1 = -0.06/-0.01] and less increase in heart rate [ MT2/T1 = 0.03/0.06] after the stress induction). No further improvements were revealed after adding ER training. However, when considering the weight changes, the significant results in resting heart rate and HF-HRV and heart rate reactivity decreased in the control group, and additional improvements in psychophysiological parameters were discovered in the experimental group. The results suggest that MOT may effectively reduce physiological stress responses and also provide preliminary evidence for a potential additional effect of ER training. Further research in a larger sample with extended follow-up measurements is needed.

Psychophysiological stress response after a 6-week Mindful Self-Compassion training in psychiatric rehabilitation inpatients: a randomized post-test only study.

Mindfulness-based interventions (including self-compassion interventions) are effective in improving stress management at psychological and physical levels. Mindful Self-Compassion (MSC) is a newly developed program particularly aimed at increasing self-compassion. The main objective of this study was to determine whether the psychophysiological stress response during a social-evaluative speaking task differs in inpatients participating in the MSC or the Progressive Muscle Relaxation (PMR) program at the end of their 6-week psychiatric rehabilitation stay (i.e., post-test only design). Data from 50 inpatients (25 MSC, 25 PMR, 35 female) aged 19 to 76 years (M = 47.22, SD = 12.44) were analyzed in terms of psychophysiological stress response. For this purpose, heart rate variability, heart rate, and blood pressure were assessed together with several psychometric variables: positive and negative affect (PANAS), subjective stress perception (Visual Analog Scale), self-compassion (Self-Compassion Scale), cognitive reappraisal and suppression (Emotion Regulation Questionnaire), psychological distress (Brief Symptom Inventory-18), and appraisal and rumination (selected items). After correction for alpha inflation no differences in the psychophysiological stress response and psychometric parameters between the MSC and PMR group were found. In general, our results indicate that MSC is not superior to PMR training. However, more research with clinical randomized controlled trials investigating larger samples are needed to further affirm these initial findings.

Personality traits influence the psychophysiological anticipatory stress responses and the effectiveness of coping interventions

Personality traits influence the psychophysiological anticipatory stress responses and the effectiveness of coping interventions

Psychophysiological Stress Response of Novel Students in Chemical Laboratory Practices

Abstract. The aim of the present study was to analyze the psychophysiological stress response of novel pharmacy and biotechnology students in chemistry laboratory practices. Autonomic stress response was analyzed in 66 students by considering heart rate variability (HRV) values before, during, and after their first laboratory practice, as well as their distress perception before and after this activity. In the laboratory practice, students had to deal with toxic products, sharp objects, or irritating substances while being examined by the teachers. Consistent with a large anticipatory anxiety response at the beginning of the practice, results showed low HRV values, generally related to a typical sympathetic modulation. This sympathetic effect persisted during the entire laboratory practice. Moreover, just after the end of the practice, there was an attenuation of the sympathetic activation and a takeover by the parasympathetic system, as revealed by the increase of HRV parameters. Laboratory practices performed by novel Pharmacy and Biotechnology students did not produce the expected habituation response at psychophysiological level since, in addition to an anticipatory anxiety response observed prior to the laboratory practice, a high sympathetic autonomic activation was observed during the whole practice. In brief, using HRV parameters could be a useful tool to analyze stress responses in students and to help them with new strategies to improve routine evaluation procedures.

Cognition, Behavior, Sexuality, and Autonomic Responses of Women with Hypothalamic Amenorrhea.

(1) Background: Functional Hypothalamic Amenorrhea (FHA) can be caused by the hyper activation of neuro-endocrine responses to stress. Among other endocrine factors and hypothalamic dysfunctions, the psychophysiological stress response can very frequently lead to an inhibition of the gonadal-pituitary axis. The aim of this study was to investigate the level of neurovegetative activation in a group of young women affected by this condition. (2) Methods: Twenty-five women (mean age = 21.1 ± 4.34) with FHA were consecutively recruited. Information on psycho-physiological distress was collected through a Psychopathological assessment (with the administration of three psychometric tests) and the Psychophysiological Stress Profile (PSP). Their data were compared with a control group. (3) Results: In the PSP, the patients displayed significantly higher values compared to controls in terms of the parameters of muscle tension (sEMG), skin conductance (SCL/SCR), heart rate (HR), and peripheral temperature (PT). Furthermore, autonomic hyper-activation at rest, marked reactivity to stress, and reduced recovery were seen. Moreover, a condition characterized by psychological distress (anxiety and somatic complaints, depressed and irritable mood, obsessive-compulsive traits) emerged. (4) Conclusions: The results highlight autonomic hyper-activation in FHA, which is also associated with psychological distress. Considering that FHA is a condition that affects multiple systems between mind and body, a multimodal, multidimensional, and multidisciplinary assessment of stress is becoming an emerging need.

Physiological Stress as Risk Factor for Hypersensitivity to Contrast Media: A Narrative Review of the Literature and a Proposal of Psychophysiological Tools for Its Detection

The use of contrast media in clinical diagnostic practice has increased significantly in recent years, accompanied by an increase in adverse reactions. These are the fleeting symptoms most complained about by patients: Flushing of the face, feeling of nausea, and heat lasting a few seconds, considered side effects related to the drug. Hypersensitivity reactions are rarer but dangerous and are driven by the immune system. To ensure the optimal management of adverse reactions to iodinated contrast media, various types of health specialists, such as radiologists, are looking into how to deal with the problem. While there are many suggestions in the scientific literature on what to do in the case of important reactions during or after radiological examination, unfortunately, there are no studies on primary and secondary prevention and, in particular, on psychophysical and psychophysiological influences. Some inferences could be made by observing the studies about psychophysiological stress and immune-inflammatory processes of allergies. The few studies in the literature on the analysis of processes affecting both psychophysiological stress and allergic responses have been analyzed. Finally, stress measurement methods are proposed that can highlight “hypersensitive” people with physiological characteristics capable of exacerbating or accentuating an allergic reaction to contrast media.

Healthy versus unhealthy comfort eating for psychophysiological stress recovery in low-income Black and Latinx adults

Low-income Black and Latinx individuals are disproportionately vulnerable to chronic stress and metabolic disease. Evidence suggests that these populations engage in elevated levels of comfort eating (i.e., eating comforting food to alleviate stress), which can harm diet quality. For this reason, many interventions discourage comfort eating. However, if comfort eating does indeed buffer stress, it may be a protective health behavior, particularly if healthy foods (e.g., strawberries) buffer stress as effectively as traditional unhealthy comfort foods (e.g., brownies). By choosing healthy foods, people may be able to simultaneously improve their nutrition and reduce their stress levels, both of which have the potential to reduce health disparities among chronically stressed populations. The present study tested the efficacy of healthy and unhealthy comfort eating for improving psychophysiological stress recovery. A sample of low-income Black and Latinx individuals (N = 129) were randomly assigned to consume a healthy food (e.g., grapes), unhealthy comfort food (e.g., chips), or no food after exposure to a laboratory stressor. Throughout, we measured participants' psychophysiological stress responses, including self-reported stress, rumination, autonomic nervous system activation (i.e., electrodermal activity (EDA), heart rate variability (HRV)) and neuroendocrine responses (i.e., salivary cortisol). We compared participants' stress recovery trajectories by condition and found no significant group differences (p = 0.12 for self-reported stress; p = 0.92 for EDA; p = 0.22 for HRV, p = 1.00 for cortisol). Participants in all conditions showed decreases in self-reported stress and in cortisol post-stressor (ps < 0.01), but rates of decline did not differ by condition (i.e., healthy or unhealthy comfort food, brief no-food waiting period). Although null, these results are important because they challenge the widely-held assumption that comfort foods help people decrease stress.

Pulling the Trigger: The Effect of a 5-Minute Slow Diaphragmatic Breathing Intervention on Psychophysiological Stress Responses and Pressurized Pistol Shooting Performance.

This study examined the effect of slow diaphragmatic breathing on psychophysiological stress responses and pressurized performance. Sixty-seven participants (40 female; Mage = 20.17 ± 2.77years) were randomly assigned to either a diaphragmatic-breathing, paced-breathing, or control group. Participants completed a nonpressurized shooting task and then received instructions about a pressurized version. Next, the diaphragmatic group was told to breathe at 6 breaths/min, the paced group at 12 breaths/min, and the control group received no instructions. Following a 5-min intervention period, participants completed the pressurized task while performance was assessed. Psychophysiological stress responses (e.g.,cognitive anxiety, heart rate) were recorded throughout. Results revealed that diaphragmatic breathing had mixed effects on stress responses, with some unaffected (e.g.,heart rate) and others reduced (e.g.,cognitive anxiety), and little effect on performance. Findings suggested that slow diaphragmatic breathing might not aid pressurized performance but could benefit psychological stress responses.

Unique Contributions of Maternal Prenatal and Postnatal Emotion Dysregulation on Infant Respiratory Sinus Arrhythmia.

Prenatal intrauterine exposures and postnatal caregiving environments may both shape the development of infant parasympathetic nervous system (PNS) activity. However, the relative contributions of prenatal and postnatal influences on infant respiratory sinus arrhythmia (RSA)-an index of PNS functioning-are relatively unknown. We examined whether prenatal and postnatal maternal emotion dysregulation, a transdiagnostic construct that spans mental health diagnoses, were independently related to infant RSA trajectories during a social stressor, the still-face paradigm. Our sample included 104 mothers and their 7-month-old infants. Maternal emotion dysregulation was measured with the Difficulties in Emotion Regulation Scale during the 3rd trimester of pregnancy and again at a 7-month postpartum laboratory visit. Infant RSA was recorded during the still-face paradigm. Only postnatal maternal emotion dysregulation was associated with infant RSA. Specifically, high postnatal emotion dysregulation was associated with a blunted (i.e., dampened reactivity and recovery) infant RSA response profile. Infant sex did not moderate the associations between maternal emotion dysregulation and infant RSA. Findings suggest that postnatal interventions to promote effective maternal emotion regulation may reduce risk for infants' dysregulated psychophysiological stress responses.

Psychophysiological stress response in SCUBA divers: The contribution of negative automatic thoughts and negative emotions

The research questions in this study were to examine the contribution of negative automatic thoughts and negative emotions, measured by two newly-constructed questionnaires, to psychophysiological stress responses among more experienced military and less experienced recreational divers. Further, we examined whether daily variations in cortisol levels could be attributed to the impact of negative thoughts/emotions rather than diving experience. Altogether 15 recreational and 14 military male divers participated in the dive wherein stress responses were measured by anxiety measures (DASS-21 and STAI) and cortisol salivary concentrations. The results of factor analysis and principal component analysis demonstrated acceptable construct validity and internal consistency of both questionanires. Recreational and military divers did not differ significantly in the proportion of negative thoughts and emotions, while recreational divers had significantly higher levels of cortisol release after awakening and immediately before/after diving, indicating their more intense stress responses. A significant interaction between daily variations in cortisol secretion and negative emotions indicated a greater importance of emotions in response to diving stress rather than diving experience. Accordingly, using a multiple regression analysis showed that more pre-diving negative emotions predicted higher levels of pre-diving anxiety and depression as well as more cortisol release. More negative thoughts predicted higher levels of depressive symptoms, while belonging to a group of recreational divers was a significant predictor of higher pre-diving anxiety. This study points to the importance of considering cognitive and emotional experiences, particularly in recreational divers, for the purpose of prevention of negative psychophysiological stress responses prior to diving.

Modification in Psychophysiological Stress Parameters of Soldiers after an Integral Operative Training Prior to a Real Mission

(1) Background. Military personel could be defined as “Tactical Athletes”. However, experimental evidence about the effects of new HIIT trainings in comparison with traditional training schedules is lacking. The aim of this study was to experimentally analyze the modifications on psycho-physiological and performance response of soldiers after completing experimental integral operative training. (2) Methods. A total of 43 male subjects of a special unit force of the Spanish armed forces were randomly selected and assigned into the experimental and control groups assessed after training and after deploying in a real operation area. The experimental group underwent an integral operative pre-mission 6-week training (IOT), and the control group, the 6-week traditional training. (3) Results. HIIT-based integral operative training significantly improved combat performance (melee combat score) and the psychophysiological stress response, as measured by heart rate variability indexes. (4) Conclusion. This study provides experimental evidence supporting a new integral operative effective for improved autonomic regulation, reduced perceived stress, melee and close-quarter combat techniques, in addition to aerobic and anaerobic performance and lower body strength in comparison with the traditional training.

The Effect of Studying a Double Degree in the Psychophysiological Stress Response in the Bachelor's Thesis Defense.

The aim of this research was to analyze the effect of studying a single or double degree in the psychophysiological stress response and academic performance of university students in their bachelor’s thesis defense. We analyzed the autonomic stress response, cortical arousal, subjective distress perception, and the sense of objective and subjective academic fulfilment of 84 single-degree physiotherapy students and 26 double-degree sport sciences and physiotherapy students during their bachelor’s thesis defense. The results showed that the bachelor’s thesis defense was a stressful event for double-degree students, showing an activation of the sympathetic nervous system and presenting a higher autonomic habituation response for the double degree students compared to the single degree students. We found higher mean grades during the whole degree and higher grades in the written and oral bachelor’s thesis academic achievements for single-degree students compared to double-degree students. No significant differences were found between single-degree and double-degree students in subjective distress perception and cortical arousal. No correlation was found between academic performance variables and subjective distress perception, cortical arousal, and autonomic modulation variables. We conclude that the bachelor’s thesis defense produces a large anticipatory anxiety response in single-degree physiotherapy students and in double-degree sport sciences and physiotherapy students. Double-degree students showed higher levels of habituation and adaptability to the stressful event, with a better autonomic response. Academic achievements were significantly higher among single-degree students compared to the double-degree group.

Associations between psychophysiological stress responses, inflammatory markers, and CSF biomarkers in the spectrum of Alzheimer’s disease

AbstractBackgroundAlthough genetic factors associated with the aggregation of misfolded proteins clearly play a role in Alzheimer’s disease (AD), several individual difference factors have been seen to confer an increased risk for the clinical manifestation of AD as well as the development of AD pathology. One of the key factors is an individual’s susceptibility to psychological stress. The goal of this study was to examine the relationships between psychophysiological stress responses measured by plasma stress hormones and neuropsychiatric symptoms, inflammatory markers, and AD pathology along the spectrum of AD.MethodAlzheimer’s Disease Neuroimaging Initiative (ADNI) consists of 819 adult subjects— 229 cognitively normal older adults (CNs), 398 participants with mild cognitive impairment (MCIs), and 192 patients with AD. Of these subjects, we included 58 CNs, 396 MCIs, and 112 AD patients whose plasma stress measures were available. Plasma cortisol and cytokines and CSF Aβ1‐42, t‐tau, and p‐tau181 data were downloaded from ADNI. Neuropsychiatric Inventory (NPI‐Q) total scores were used to indicate a psychological stress level.ResultAD stages were significantly related to the level of plasma cortisol and NPI‐Q total scores showing that AD patients exhibit the highest level of cortisol and greater severity of psychological symptoms followed by MCIs and CNs. AD stages were also significantly related to the level of inflammatory markers measured by cytokines, although the level of inflammatory markers in relation to the diagnostic groups varied across different types of cytokines. Plasma cortisol levels did not relate to concurrent levels of CSF Aβ1‐42 either across diagnostic groups or within diagnostic groups. Higher plasma cortisol, however, corresponded to higher CSF p‐tau among CNs, but not in MCIs and ADs.ConclusionPsychophysiological stress responses and inflammatory markers are significantly associated with the disease severity. A positive relationship between plasma cortisol level and CSF p‐tau in CNs may indicate a role of individuals’ susceptibility to stress in neuronal hyperexcitability in the early stage of AD and confer a risk of neurodegeneration and the development of AD. Alleviating stress and regulating stress responses may be important modifiable factors that help prevent AD.

Split-Second Unlearning: Developing a Theory of Psychophysiological Dis-ease.

Psychophysiological “stress” underpins many conditions including anxiety, depression, phobias, chronic fatigue syndrome and non-specific musculoskeletal pain such as fibromyalgia. In this article we develop an understanding of chronic psychophysiological stress from a psychological educational perspective, by drawing on supporting evidence that significant emotional events in early life (traumatic and benign) can influence health and well-being later in life. We suggest that traumatic events instigate psychophysiological “stress” responses and the formation of emotional memory images (EMIs) within very short time frames, i.e., “split-second learning.” Once formed these emotional memories are triggered in daily living “re-playing” psychophysiological stress responses, resulting in chronic psychophysiological “dis-ease.” We describe a novel therapeutic approach to scan clients for mannerisms signifying a subconscious “freeze-like” stress response that involves the client as a curious observer within their own experience, feeding back the non-verbal cues as they arrive in the moment. By breaking down the observable fragments of their split-second Pavlovian response to the trigger, clients can detach their EMI from the psychophysiology stress response, i.e., “split-second unlearning.” Our split-second unlearning model recognizes the EMI as a barrier to moving forward and needs to be unlearned before the client can become naturally adaptive again. We argue that this approach places the client at the center of the work without the need of getting bogged down in a life-long narrative.

Effects of Hypoxia on Selected Psychophysiological Stress Responses of Military Aircrew.

There is a lack of information on the psychophysiological response of pilots under hypoxic conditions. The study of the physiological, psychological, cardiorespiratory, neurological, behavioural, sensory, and cognitive symptoms that may appear during training in hypobaric chambers is essential to optimize the training processes of aircrew members. Thus, the present study is aimed at analyzing the psychophysiological responses of aircrew members in an incremental hypoxia training protocol. Psychophysiological responses of 44 aircrew members (34 males and 10 females) in an incremental hypoxia training protocol (3 minutes at 0 meters, 8 minutes at 5,000 meters, and maximum time at 7500 meters) were measured. Results suggested that the incremental hypoxia training protocol did not affect cortical arousal and handgrip strength; however, it increased the sympathetic tone, perceived stress, perceived effort, and heart rate and decreased forced expiratory volume and blood oxygen saturation. Thus, we concluded that acute hypoxic hypobaric exposure leads to decreased parasympathetic tone, blood oxygen saturation, and maximal spirometry values, without negatively affecting handgrip strength and cortical arousal. This information will lead to find specific training systems that meet the real needs of aircrew.

P016 - Coping strategies and psychophysiological stress response of newly-diagnosed prostate cancer patients

P016 - Coping strategies and psychophysiological stress response of newly-diagnosed prostate cancer patients

Combining proactive transcranial stimulation and cardiac biofeedback to substantially manage harmful stress effects

BackgroundPrevious studies have identified the dorsolateral prefrontal cortex (dlPFC) as a core region in cognitive emotional regulation. Transcranial direct current stimulations of the dlPFC (tDCS) and heart-rate variability biofeedback (BFB) are known to regulate emotional processes. However, the effect of these interventions applied either alone or concomitantly during an anticipatory stress remains unexplored. ObjectiveThe study investigated the effect of anodal tDCS and BFB, alone or combined, on psychophysiological stress responses and cognitive functioning. MethodsFollowing a stress anticipation induction, 80 participants were randomized into four groups and subjected to a 15-min intervention: neutral video viewing (ctrl), left dlPFC anodal tDCS (tdcs), heart-rate variability biofeedback (bfb), or a combined treatment (bfb + tdcs). Participants were then immediately confronted with the stressor, which was followed by an assessment of executive functions. Psychophysiological stress responses were assessed throughout the experiment (heart rate, heart-rate variability, salivary cortisol). ResultsThe tdcs did not modulate stress responses. Compared with both ctrl and tdcs interventions, bfb reduced physiological stress and improved executive functions after the stressor. The main finding revealed that bfb + tdcs was the most effective intervention, yielding greater reduction in psychological and physiological stress responses than bfb. ConclusionsCombining preventive tDCS with BFB is a relevant interventional approach to reduce psychophysiological stress responses, hence offering a new and non-invasive treatment of stress-related disorders. Biofeedback may be particularly useful for preparing for an important stressful event when performance is decisive.