Event Abstract Back to Event fMRI-based neurofeedback in schizophrenia: ACC and hallucinations Klaus Mathiak1* 1 RWTH Aachen University, Dept. Psychiatry, Psychotherapy and Psychosomatics, Germany Schizophrenia is characterized by neural dysregulation in – among others – the salience network. fMRI-based neurofeedback may normalize network functions by addressing central nodes or distributed patterns. We show, first, that voluntary regulation of monitoring nodes such as the ACC activation is feasible even in patients with ongoing auditory verbal hallucinations (AVH). Indeed, moderated by clinical variables, such regulation may affect the appraisal of AVHs. Second, regulation of network for language processing suggests differential roles of left inferior frontal gyrus (Broca’a area) and the posterior part of the superior temporal gyrus (Wernicke’s area). Neurofeedback training based on fMRI can address specific networks underlying psychopathology in schizophrenia. For meaningful therapeutic effects, however, individual disease and symptom profiles need to be taken into account. Acknowledgements Federal Ministry of Education and Research (APIC: 01EE1405B, 01EE1405C) German Research Foundation (DFG; MA 2631/6-1) Keywords: Neurofeedback, Schizophrenia, Hallucinations, fMRI BOLD, Cingulate cortex, Broca's area, Wernicke's area Conference: SAN2016 Meeting, Corfu, Greece, 6 Oct - 9 Oct, 2016. Presentation Type: Oral Presentation in the Symposium in Novel therapies for patients with schizophrenia: neurofeedback Topic: Symposium in Symposium in Novel therapies for patients with schizophrenia: neurofeedback and neurostimulation Citation: Mathiak K (2016). fMRI-based neurofeedback in schizophrenia: ACC and hallucinations. Conference Abstract: SAN2016 Meeting. doi: 10.3389/conf.fnhum.2016.220.00078 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 25 Jul 2016; Published Online: 01 Aug 2016. * Correspondence: Prof. Klaus Mathiak, RWTH Aachen University, Dept. Psychiatry, Psychotherapy and Psychosomatics, Aachen, 52074, Germany, kmathiak@ukaachen.de Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Klaus Mathiak Google Klaus Mathiak Google Scholar Klaus Mathiak PubMed Klaus Mathiak Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.