Event Abstract Back to Event A voxel-based morphometric MRI study in psychopathic traits Hiroki Fukui1*, R. Kawada1 and K. Yoshikawa1 1 National Institute of Mental Health, Japan Purpose: Psychopathy is characterized by a failure to experience emotions that are necessary for appropriate social behavior, such as empathy. These characters are considered to construct a latent dimension rather than a latent taxon. Non-clinical individuals are relatively free of potentially confounding variables (e.g., severe substance use, physical abuse history) that can often complicate the interpretation of brain-imaging deficits. Our aim was to examine whether a specific association exists between abnormalities of brain structures and psychopathic traits in community samples. Furthermore, we explored the correlation between the psychopathic trait- related structures and empathic abilities. Method: Twenty-two healthy subjects underwent structural magnetic resonance imaging and their psychopathic tendency was examined using the self-rating questionnaire Levenson Self-Report Psychopathy Scale (LSRP) and Psychopathic Personality Inventory-Revised (PPI-R). We applied voxel-based morphometry to investigate regional brain volume alternations. We employed the Empathic Concern (EC) Subscale of the Interpersonal Reactivity Index (IRI) to measure empathic abilities and assessed the correlation with the brain volume of psychopathy-associated areas. Results: An association between the LSRP total score and volume reductions in the right precuneus (Prc) was identified. Scores of LSRP primary psychopathy scores were correlated with the bilateral Prc, right orbitofrontal cortex (OFC), and right amygdala volume decrease. The scores of the EC Subscale of IRI scores were not associated with the structural abnormality of the amygdala or OFC, but were associated with the right Prc. Conclusion: Our findings support the view that psychopathy is a dimension in the brain structure level. We suggest that the precuneus may play an important role in the empathy of psychopathic people, by its third-person perspective-taking function. Conference: 10th International Conference on Cognitive Neuroscience, Bodrum, Turkey, 1 Sep - 5 Sep, 2008. Presentation Type: Poster Presentation Topic: Cerebral Asymmetry Citation: Fukui H, Kawada R and Yoshikawa K (2008). A voxel-based morphometric MRI study in psychopathic traits. Conference Abstract: 10th International Conference on Cognitive Neuroscience. doi: 10.3389/conf.neuro.09.2009.01.142 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 05 Dec 2008; Published Online: 05 Dec 2008. * Correspondence: Hiroki Fukui, National Institute of Mental Health, Tokyo, Japan, fukui@ncnp.go.jp Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Hiroki Fukui R. Kawada K. Yoshikawa Google Hiroki Fukui R. Kawada K. Yoshikawa Google Scholar Hiroki Fukui R. Kawada K. Yoshikawa PubMed Hiroki Fukui R. Kawada K. Yoshikawa Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.
Read full abstract