introduction: Increased morbidity and mortality associated with chronic kidney disease (CKD) negatively affects patient’s Quality of life (QOL), which is an issue of significant public health importance. Thus, the aim of this study is to assess impact of physical, psychological, social and demographic variables on quality of life among patients with ESRD undergoing Haemodialysis. Objectives: 1. To assess the Quality of Life of patients undergoing hemodialysis.2. To study the socio-demographic factors associated with Quality of Life. 3.To assess Patient Satisfaction in patients related to services provided in the tertiary care hospital Methodology: A cross-sectional study was conducted in dialysis unit of a tertiary care hospital in Navi Mumbai. All patients(n=51) who are ?18 years of age undergoing haemodialysis for at least 3 months were included. The study was conducted using Kidney Disease Quality of Life 36 item scale and Patient Satisfaction questionnaire. Results: The Physical component score (PCS) was 33.028.82 and Mental component score (MCS) was 42.057.23. The mean score of patient satisfaction was 66.255.75. Conclusion and Recommendation: The present study showed that kidney disease had a greater effect on physical health than mental health. Also, patients report satisfaction with the healthcare received at the health facility.