Sleep is an important indicator of physical and mental health. Little is known about the quality, pattern and correlates of sleep among Indian adults. This study was aimed to analyze the quality of sleep in medical students using the Pittsburgh Sleep Quality Index and to relate sleep with blood pressure, body mass index and academic performance. The sample consisted of 67 medical students in the age group of 18–22 years. 28(42%) medical students had ‘poor sleep’. 57% reported inadequate sleep and 54% had sleep disturbances. ‘Poor sleepers’ had higher blood pressure, body mass index and lowered academic performance compared with good sleepers. Global PSQI score showed significant positive correlation with blood pressure and body mass index but not with academic performance. This study shows the high prevalence of poor sleep quality and underline the close relationship of sleep with BP, BMI and academic performance among medical students.