Objective To observe the clinical effects of Linpixin spraying agent on bedsore of Ⅱ、Ⅲ stage. Methods A total of 38 patients with bedsore of Ⅱ、Ⅲ stage were randomly divided into two groups: 25 bedsore in 19 patients of the observatation group were coated by Linpixin every day, the control group of other 19 patients cover mupirocin ointment of 1 mm thickness on the 22 bedsore. Healing time and recovery rate in 2 weeks were observed, the outcomes were calculated and analyzed. Results The healing time on observation group was (7.32±2. 61 ) days, in the control group was (13. 1 ±4. 32) days, the observation group's healing time was statistically shorter than that of the control group , the 2 weeks recovery rate of the observation group was 96.0%, it's better than the control group's 81.8%.Conclusions Linpixn spraying agent has a good effect on bedsore of Ⅱ、Ⅲ stage , it can reduce the healing time and improve the recovery rate. Key words: Linpixin spraying agent; Bedsore; Treatment