This study investigates the geochemical characteristics and evolutionary implications of sediments at the confluence of the Xingu and Amazon Rivers. The main objective is to understand sediment mixing, mobility, and weathering processes through geochemical proxies. Samples were collected from various sections of the lower Xingu River, focusing on its interaction with the Amazon River. Analytical techniques such as X-ray diffraction (XRD), X-ray fluorescence (XRF), and inductively coupled plasma mass spectrometry (ICP-MS) were employed to analyze major and trace elements. The results reveal significant spatial variations in mineralogical and textural patterns, with sediments forming distinct groupings based on their location. The data suggest that the lower Xingu River is strongly influenced by sediment inputs from the Amazon River, particularly affecting sediment composition and chemical weathering processes. This research highlights the critical interactions between river systems and their implications for the evolution of the Amazon basin, especially regarding sediment contributions from various geological sources. Even though the Xingu River drains cratonic regions at higher elevations, the geochemistry of the bottom sediments confirms that the bedload is derived from heterogeneous sources with primarily intermediate igneous compositions and has undergone substantial recycling during river transport.