Provisional Results Research Articles

Abstract PO1-11-10: Use of a standardized tool for the evaluation and treatment of cancer related cognitive impairment (chemo-brain) among breast cancer patients

Abstract There is a steep linear increase in patients surviving a cancer diagnosis. Clinical solutions that address the high prevalence of cancer-related treatment effects (CRTE) are urgently needed. A stark example of this need is the dearth of screening and treatment programs for cancer related cognitive impairment (CRCI) (colloquially called “chemo-brain”). Up to 75% of cancer patients report neurocognitive changes that leave patients unable to cope with the expectations of employers, colleagues, families, and friends. The prevalence of neurological disorders is 275% higher among adult cancer patients, when compared to an adult cancer-free population. For many adolescent and young adult cancer patients, the onset of CRCI occurs during "cognitive prime time"; a time when individuals are pursuing education, careers, and raising families. To address a gap in CRTE we have implemented a virtual multi-disciplinary intervention to measure and treat CRCI. Our CRCI intervention follows National Comprehensive Cancer Network and American Society of Clinical Oncology (ASCO) guidelines for CRCI. These guidelines indicate a multi-disciplinary approach with emphasis on increasing physical activity levels, cognitive-behavioral therapy, memory adaptive training, mood management, and sleep optimization. Our approach also follows recent ASCO guidelines for nutrition counseling. Our CRCI program utilizes medical oncologists, physician assistants, mental health therapists, registered dietitians, and occupational therapists. A nationally validated patient reported outcome (PRO) measurement, analysis, and reporting platform informs clinical treatment pathways, monitors patient progress, guides clinical decision making, and improves patient/provider communication. Using health status measures for CRCI, and following American Cancer Society and ASCO guidelines, patients are risk-stratified into three personalized cancer survivor care pathways: 1) low-complexity patients; 2) medium-complexity patients; and 3) high-complexity patients. Low-complexity patients baseline PROs score in the normal range, medium-complexity patients are those who score below the norm (moderate to large effect size difference from normal), and high-complexity patients are those who score well below the norm (greater than larger effect size difference from normal). Low-complexity patients are enrolled into a self-management and continuation of care program. Medium-complexity patients are enrolled into a shared care program. High-complexity patients are enrolled into an acute care program. All three clinical pathways include continued risk-factor vital-sign surveillance. Nearly 100% (99%) of patients who enroll in our primary cancer survivor care program complete our PRO baseline (N=80). From a convenient sample of breast cancer patients (N=42), provisional results of patient-specific segmentation analyses reveal a nearly perfect bell-shaped curve, with 51% of the population classified within the definition of medium-complexity and even split of outliers (high-complexity 24% and low-complexity 24%). Additionally, of all patients in our primary cancer survivor care program who completed at least three measurement time points for health status measures of cognitive impartment (N=38), 92% had a positive experience, 71% had a clinically significant improvement in cognitive health, 21% had a no change in cognitive status, and only 8% had a decline in cognitive health. If these data, and PRO implementation approach hold true, this program could be scaled to national and international cancer survivor population suffering from CRCI. Citation Format: John Librett, Mark Kosinski, Gregory Litton. Use of a standardized tool for the evaluation and treatment of cancer related cognitive impairment (chemo-brain) among breast cancer patients [abstract]. In: Proceedings of the 2023 San Antonio Breast Cancer Symposium; 2023 Dec 5-9; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2024;84(9 Suppl):Abstract nr PO1-11-10.

Navigating Vicarious Trauma: The Importance of Planning, Teaching, and Delivering Vicarious Trauma Training to Support Law Students and the Legal Profession

The significant effects of Vicarious Trauma (VT) are now being recognised in various professions, including law where the requirement for trauma informed practice’”[1] is now starting to be recognised. VT can be defined as: “a process of change resulting from empathetic engagement with trauma survivors. Anyone who engages empathetically with survivors of traumatic incidents, torture, and material relating to their trauma, is potentially affected” . Trauma- informed practice then focusses on how to work with those who have been impacted by their traumatic experience as a result of exposure to reading, writing, and hearing details of cases that they deal with. This may lead to a one-off feeling of despair or may be the result of the cumulative effect from working constantly with complicated, sensitive, and emotional materials and people. The legal professional may take on the emotions of a client and experience trauma that puts them in the place of the individual that they are trying to assist. Certain areas of the profession may be more prone to such experiences, for example criminal lawyers dealing with such cases as murder, manslaughter, and serious sexual offences. These feelings can be overwhelming, even for the most experienced practitioner. VT too, may also be experienced by students participating in Clinical Legal Education (CLE) undertaken in universities, again impacting on those involved in criminal case work where students have their first exposure to complicated and sensitive cases. This article considers the experience of members of the Criminal Justice Clinic (CJC), within the Open University (OU) and looks at the scope and impact of the VT training that is being delivered and its importance in preserving students’ mental well-being. Added is the factor of this being an online only clinic where isolation can also be an issue. There is a need to provide VT training to support the mental welfare of students, and staff alike. This training is paramount to the success of the CJC and is pivotal to any CLE provision and should be expanded to the law curriculum and onto legal practice. This article argues that the experience in the CJC demonstrates that there is a need for professional legal education to recognise and address the incidence of VT and to provide skills to those who may be affected. Consideration is given to measures that should be adopted in the delivery of CLE to support students participating in pro bono projects. This should carry on beyond university into their future careers. A brief mention will be made of the provisional results of a small-scale research project in this area. Another article is planned to discuss those results fully in the future. [1] Victims, Witnesses, and Justice Reform (Scotland) Bill as introduced references the introduction and definition of trauma -informed practice. https://www.parliament.scot/-/media/files/legislation/bills/s6-bills/victims-witnesses-and-justice-reform-scotland-bill/introduced/https://www.parliament.scot/-/media/files/legislation/bills/s6-bills/victims-witnesses-and-justice-reform-scotland-bill/introduced/bill-as-introduced.pbill-as-introduced.pdf (accessed 12th January 2024).

Scanning efficacy of p-Chips implanted in the wing and leg of the Big Brown Bat (Eptesicus fuscus).

Individual marking techniques are critical for studying animals, especially in the wild. Current marking methods for bats (Order Chiroptera) have practical limitations and some can cause morbidity. We tested the p-Chip (p-Chip Corp.)-a miniaturized, laser light-activated microtransponder-as a prospective marking technique in a captive research colony of Big Brown Bats (Eptesicus fuscus). We assessed long-term readability and postimplantation effects of p-Chips injected subcutaneously above the second metacarpal (wing; n = 30) and the tibia (leg; n = 13 in both locations). Following implantation (Day 0), p-Chips were scanned with a hand-held ID reader (wand) on postimplantation days (PIDs) 1, 8, 15, 22, 32, 60, 74, 81, 88, 95, and over 1 year later (PID 464). For each trial, we recorded: (1) animal handling time; (2) scan time; (3) number of wand flashes; (4) p-Chip visibility; and (5) overall condition of the bat. Average scan times for p-Chips implanted in both the wing and leg increased over the duration of the study; however, the number of wand flashes decreased, suggesting that efficacy of p-Chip recording increased with user experience. Importantly, over 464 days both the visibility and readability of p-Chips in the wing remained high and superior to tags in the leg, establishing the second metacarpal as the preferred implantation site. Observed morbidity and mortality in captive bats with p-Chips was similar to baseline values for bats without these tags. Because scan efficiency on PID 464 was comparable with earlier days, this indicates that p-Chips implanted in the wing may be suitable as a long-term marking method. Our provisional results suggest that p-Chips are viable for extended field testing to see if they are suitable as an effective alternative to traditional methods to mark bats.

The Soteria project recounted by Mosher and its clinical resonances today.

The American psychiatrist Loren R. Mosher has passed to posterity as an eager proponent of a psychosocial approach to psychosis. The best example of this is the Soteria project that he founded in San Jose, California, in the 1970s. The contribution of Alma Zito Menn, ACSW, also merits attention as project director of Soteria and for her links to the Mental Research Institute, Palo Alto. She was later replaced as program director by Voyce Hendrix, LCSW, when she turned to other preoccupations linked to the grant continuation of Soteria. Equally, the nonprofessional staff of the facility should receive appreciation. Bearing this in mind, the main aim of this paper is to reflect upon the Soteria project, giving voice to Mosher himself, while simultaneously connecting his ideas with other empirical works that have been published on this topic in recent decades. Using a selection from the extant literature assessing the implementation and outcomes of adapting Soteria-elements to different settings, I present here provisional results obtained from current research. First, I expound what Mosher hoped to achieve in creating Soteria and why it worked. In this respect, I go beyond what is commonly reported in scholarly works, where the Soteria project is considered without paying too great attention to its main architect, as if the project could be separated from the man who created it. As I have corroborated here, there is today growing and promising scientific evidence validating the principles of the Soteria project. Undoubtedly, this would not have been possible without the pioneering work of Mosher, who, imbued with the tenets of interpersonal phenomenology, shook the psychiatric establishment, leading others to follow the path that he had begun.

(039) Challenges in Transgender Care Through a Qualitative Lens: Provisional Results About Sexual Medicine Professionals´ Opinions

Abstract Introduction Transgender people’s health and healthcare have become one of the most important challenges in healthcare settings and policy making. The perspectives of transgender consumers are important to inform policymaking and the development of measures to diminish barriers to accessing and maintaining health care. However, the perspective of healthcare providers, namely clinicians, is less known and is important to take a comprehensive and collaborative stance to deliver the best healthcare. Objective To highlight the perspective of sexual medicine practitioners/sexologists involved in transgender healthcare on the challenges faced in providing transgender healthcare. Methods Following an initiative by the Portuguese Society for Clinical Sexology, we used a participatory research design involving experienced sexual medicine clinicians/sexologists and activists for transgender care to develop a study to collect sexologists' perceptions of the challenges they faced when providing health care to transgender people. After IRB approval, we used a cross-sectional qualitative design and disseminated an online survey among professional associations (e.g., the Portuguese Society of Andrology, Sexual Medicine and Reproduction). A total of 25 complete answers were collected from clinicians who act in transgender healthcare and whose professional background included: Clinical Psychology, Pediatric Psychiatry, Psychiatry, Endocrinology, Urology, Gynecology and Anesthesiology. Participants were, on average, 46 years old (SD = 12.38), had an average of 13 years (SD = 11.25) experience in Sexual Medicine/Clinical sexology and 11 years on average (SD = 10.38) of experience with transgender healthcare. Sociodemographic data was collected between January and June 2023, and four open questions were presented. The current study will report preliminary content analysis concerning the open question: “Which challenges have you encountered in your experience as a health professional acting clinically with transgender people?”. Results The preliminary content analysis revealed 6 main categories, each representing distinct and interrelated subcategories aggregating different codes. The main categories were: 1. Formal Institutional Challenges (e.g., lack of formal education concerning transgender care, lack of specific guidelines for primary care; long waiting lists); 2. Informal Institutional Challenges (e.g., lack of updated knowledge from other clinicians not directly involved in transgender care; non-responsiveness from colleagues, translating policies and international guidelines into practices); 3. Social Challenges (e.g., family stigma; social discrimination); 4. Patient’s Challenges (e.g., lack of compliance; hostility or negative expectations towards health professionals); 5. Personal limits (e.g., perseverative thinking about the timing and patients’ internalisation of information about surgery risks; feelings of strangeness towards non-binary bodies); 6. Clinical Challenges (e.g., presence of emotional disorders/psychopathology; establishing differential diagnosis). Conclusions The current preliminary and provisional results highlight that clinical sexologists involved in transgender healthcare face different challenges regarding their role. The interrelated themes and subthemes reveal that clinical sexologists acting in transgender care have a critical stance towards policy making, service management and the quality of professional education provided to clinicians. Stigmatisation by their colleagues towards transgender people is a focus of concern. Still, they also feel they experience patients’ hostility and clinical and ethical challenges when trying to provide the best standards of care with a lack of resources. Disclosure No.

Evaluating the utility of robotic axillary lymph node dissection in patients with invasive breast cancer: a systematic review.

Robot-assisted axillary lymph node dissection (RALND) has been proposed to improve surgical and oncological outcomes for patients with breast cancer.To perform a systematic review of current literature evaluating RALND in patients with invasive breast cancer.A systematic search was performed in accordance with the PRISMA guidelines. Studies outlining outcomes following RALND were included.Two studies involving 92 patients were included in this review. Of these, 41 underwent RALND using the da Vinci© robotic system (44.57%), and 51 underwent conventional axillary lymph node dissection (CALND) (55.43%). There was no significant difference observed with respect to intra-operative blood loss or duration of procedure in those undergoing CALND and RALND (P > 0.050). One study reported a significant difference in lymphoedema rates in support of RALND (6.67% vs 26.67%, P = 0.038). Overall, data in relation to postoperative fat necrosis (10.00% vs 33.33%, P = 0.028), wound infection rates (3.33% vs. 20.00%, P = 0.044), and wound ≤ 40mm in length (63.63% vs. 19.05%, P = 0.020) supported RALND. Oncological outcomes were only reported in one of the studies, which concluded that there was no local or metastatic recurrence in either group at 3-month follow-up.These provisional results support RALND as a safe alternative to CALND. Notwithstanding, the paucity of data limits the robustness of conclusions which may be drawn surrounding the adoption of RALND as the standard of care. Further high-quality studies are required to ratify these findings.

A59Midlands Simulation and Immersive Learning Census 2023: A Cross-sectional study to inform regional TEL strategy

National Health Service England (NHSE) is committed to providing the highest quality, evidence-based and sustainable Technology Enhanced Learning (TEL) to the workforce of tomorrow [1]. Over the past 20 years, simulation-based education (SBE) facilities have developed across many NHS trusts, universities, and training programmes using different models of delivery and funding to match their local needs. More recently, technological advances and a pandemic-driven need for remote and supplementary training experiences has expanded the remit of TEL. Our objective was to complete a wide-ranging census to map simulation and immersive learning (SimImm) resources across an entire NHSE region and how these are delivered. Most importantly, we aim to gather stakeholder opinions on the perceived challenges faced by the SimImm community in the coming 3-5 years. In December 2022, we launched a multi-phased regional online survey of SimImm providers. Phase one distribution included members of the two regional simulation networks. Phase two was distributed to simulation leads for postgraduate schools, training programmes and higher education institutions. Throughout, other stakeholders in the SimImm community had the opportunity to complete the ‘future challenges’ section only. 35 organizations had completed the full census, with a further 47 stakeholders completing the ‘future challenges’ section. Of the full census, 14 were secondary care simulation centres, 18 training programmes and 3 universities. The most common resources used were High-fidelity simulation ( Thematic analysis of the ‘future challenges’ section, revealed 5 primary areas of perceived challenges: Faculty development, maintenance, and retention; resources funding; collaborative working; strategy and equitable opportunities and adoption of new technology. Provisional results already demonstrate a huge variety of resources which are distributed widely across the region. Many of these are not necessarily in contact with regional simulation networks, particularly individual training programmes. The stakeholder opinions collated through this exercise will form the bedrock on which regional SimImm strategy and decision-making can be based. Authors confirm that all relevant ethical standards for research conduct and dissemination have been met. The submitting author confirms that relevant ethical approval was granted, if applicable.

Satisfactory Clinical Outcome, Complications, and Provisional Results of Meniscus Centralization with Medial Meniscus Root Repair for the Extruded Medial Meniscus at Mean 2-Year Follow-Up

To describe the patient-reported clinical outcomes following medial meniscus root repair with meniscus centralization and to identify common complications and detail provisional results. Patients undergoing medial meniscus root repair with meniscus centralization from 2020 to 2022 were identified using an institutional database. Patients were followed prospectively using postoperative Tegner Activity Scale, visual analog scale (VAS) for pain, Knee Injury and Osteoarthritis Outcome Score, Joint Replacement, International Knee Documentation Committee score, and a Likert score for improvement, surgery satisfaction, and subsequent surgeries at minimum 1-year follow-up with mean 2-year follow-up. Demographics, injury characteristics, and surgical details were also collected. Twenty-five patients (age: 50 ± 11 years; sex: 76% female; body mass index: 33 ± 8) were included in this study. Postoperative Tegner score was maintained at preoperative levels (P= .233), and VAS at rest, VAS with use, Knee Injury and Osteoarthritis Outcome Score, Joint Replacement, and International Knee Documentation Committee improved significantly postoperatively (P= .003; P < .001, P < .001, P= .023, respectively). Eighty-eight percent of patients reported subjective improvement in their knee at final follow-up. Postoperative radiographs did not show any significant osteoarthritis progression, and no patients had undergone a revision meniscus surgery or total knee arthroplasty at the time of follow-up. At minimum 1-year follow-up and mean 2-year follow-up, patients undergoing medial meniscus root repair with meniscus centralization demonstrated significant postoperative improvements in pain, function, and quality of life and reported high rates of surgery satisfaction. There was no evidence of significant arthritic progression on postoperative imaging, and no patients underwent revision meniscus surgery or total knee arthroplasty. Level IV, case series.

Analysis of Child Exploitation Cases According to Law 35 of 2014 concerning Child Protection (Case Study of Supreme Court Decision Number (58/Pid. Sus/2013/PN Pti)

According to the Provisional Population Projection Results for 2022–2023 published by the Central Statistics Agency, there are 94,377.6 children between the ages of 0 and 19. Children are a responsibility and a gift from God Almighty that must be preserved since children are born with intrinsic human dignity. Children under the age of 18 are supposedly prohibited from understanding what labor is. The responsibility of the kid is to obtain the right to education and instruction in order to advance their level of intelligence and in line with their interests and abilities.

P61. Provisional results from a 35-patient multi-center pilot study of nucleus pulposus allograft for replacing tissue loss in patients with symptomatic degenerated discs

P61. Provisional results from a 35-patient multi-center pilot study of nucleus pulposus allograft for replacing tissue loss in patients with symptomatic degenerated discs

Barriers to and enablers of the promotion of patient and family participation in primary healthcare nursing in Brazil, Germany and Spain: A qualitative study.

Most health systems are insufficiently prepared to promote the participation of chronically ill patients in their care. Strong primary health care (PHC) strengthens patients' resources and thus promotes their participation. The tasks of providing continuous care to people with chronic diseases and promoting self-management are the responsibility of PHC nurses. Recent research assessing enablers of or barriers to nurses'efforts to support patients'participation has mostly not considered the special situation of patients with chronic diseases or focused on the PHC setting. To investigate enablers of and barriers to PHC nurses' efforts to promote the participation of chronically ill patients in their care. We interviewed 34 practicing PHC nurses and 23 key informants with advanced knowledge of PHC nursing practice in Brazil, Germanyand Spain. The data was analyzed using thematic coding. We identified four categories of barriers and enablers. (1) Establishing bonds with patients: Interviewees emphasized that understanding patients' views and behaviours is important for PHC nurses. (2) Cooperation with relatives and families: Good relationships with families are fundamental, however conflicts within families could challenge PHC nurses efforts to strengthen participation. (3) Communication and cooperation within PHC teams: PHC nurses see Cooperative team structures as a potential enabler, while the dominance of a 'biomedical' approach to patient care is seen as a barrier. (4) Work environment: Interviewees agreed that increased workload is a barrier to patient participation. Supporting patient participation should be acknowledged as an important responsibility for nurses by general practitionersand PHC planners. PHC nurses should be trained in communicative competencewhen discussing participation with chronically ill patients. Interprofessional education could strengthen other professionals' understanding of patient participation as a nursing task. This study is part of a research project associated with the research network 'forges: User-oriented care: Promotion of health in the context of chronic diseases and care dependency'. The study's focus and provisional results were discussed continuously with partners in health and social care practice and presented to and discussed with the public at two conferences in which patient representatives, professionals and researchers participated.

Bronze Fish

Abstract The Bronze Age was a time of pivotal economic change when new long-distance trading networks became associated with a macro-regional division of labour and decentralised political complexity. These developments occurred against the background of a shifting mosaic of subsistence patterns, which included the east-west exchange of crops across Eurasia and (in some areas) greater use of secondary products. As Bronze Age economies became more specialised and diverse, it might be assumed that there was also an increased emphasis on the procurement and trade of fish and other marine resources. However, archaeological analyses of such resources are limited in contrast to land-based subsistence patterns and many questions remain. This essay aims to build a broad interpretive framework for analysing the role of marine resources in the Bronze Age. Our provisional results find that an increased emphasis on specialist systems of agropastoralism reduced the use of marine resources in many parts of Eurasia during this period. However, evidence from Japan and the eastern Mediterranean suggests that, at least in some regions, marine resources became commodities traded over long-distances by the late Bronze Age, though this requires further quantification. Island Southeast Asia displays a different pattern from other regions considered here in a greater continuity of marine resource use from the Neolithic into the historic era, perhaps due to a lower reliance on agropastoralism.

IMPLEMENTASI UNDANG-UNDANG NO 33 TAHUN 2014 DAN TINJAUN MAQHASID ASY SYARIAH TERHADAP INDUSTRI GERAI ES CREAM MIXUE

In the current era of 4.0, the food and beverage industry in Indonesia has changed according to the needs of the communitys. Realizing the needs of the Indonesian people who have a tropical climate, China will establish its industrial business in Indonesia and make products in the form of modern ice cream. The ice cream industry in China is called Mixue. The large number of foreign products entering Indonesia has made the Indonesian government especially concerned about maintaining halal food and minimums so it issued Law No. 33 of 2014 concerning Guarantees for Halal Products. The Indonesian government gave the task to the Ministry of Religion, then the Ministry of Religion established the Halal Product Assurance Organizing Body (BPJPH). This research method is an empirical juridical research, in which the researcher wants to examine more deeply the duties of the Halal Product Assurance Organizing Agency (BPJPH) in supervising and providing halal labeling to the Ice Cream Mixue Industry whether it is by Law No. 33 of 2014 concerning Assurance Halal products in maintaining the benefit of the ummah. The provisional results show that the Ice Cream Mixue Industry does not yet have a halal logo label from (BPJPH).

Sea2Cloud: From Biogenic Emission Fluxes to Cloud Properties in the Southwest Pacific

Abstract The goal of the Sea2Cloud project is to study the interplay between surface ocean biogeochemical and physical properties, fluxes to the atmosphere, and ultimately their impact on cloud formation under minimal direct anthropogenic influence. Here we present an interdisciplinary approach, combining atmospheric physics and chemistry with marine biogeochemistry, during a voyage between 41° and 47°S in March 2020. In parallel to ambient measurements of atmospheric composition and seawater biogeochemical properties, we describe semicontrolled experiments to characterize nascent sea spray properties and nucleation from gas-phase biogenic emissions. The experimental framework for studying the impact of the predicted evolution of ozone concentration in the Southern Hemisphere is also detailed. After describing the experimental strategy, we present the oceanic and meteorological context including provisional results on atmospheric thermodynamics, composition, and flux measurements. In situ measurements and flux studies were carried out on different biological communities by sampling surface seawater from subantarctic, subtropical, and frontal water masses. Air–Sea-Interface Tanks (ASIT) were used to quantify biogenic emissions of trace gases under realistic environmental conditions, with nucleation observed in association with biogenic seawater emissions. Sea spray continuously generated produced sea spray fluxes of 34% of organic matter by mass, of which 4% particles had fluorescent properties, and which size distribution resembled the one found in clean sectors of the Southern Ocean. The goal of Sea2Cloud is to generate realistic parameterizations of emission flux dependences of trace gases and nucleation precursors, sea spray, cloud condensation nuclei, and ice nuclei using seawater biogeochemistry, for implementation in regional atmospheric models.

1415 NOVEL APPROACHES TO POST DISCHARGE CARE. REMOTE HEALTHCARE MONITORING SYSTEMS FOLLOWING TRAUMATIC BRAIN INJURY IN OLDER ADULTS

Abstract Introduction Major trauma including Traumatic Brain Injury (TBI) is an increasingly common cause of hospitalisation in older adults (OAs). We studied post-discharge recovery from TBI using a remote healthcare monitoring system that captures data on activity and sleep. We aim to assess the feasibility and acceptability of this technology to monitor recovery at home following a significant acute health event in OAs. Methods We installed Minder, a remote healthcare monitoring system, in recently discharged patients &amp;gt;60 years with moderate-severe TBI. We present descriptive analyses of post-discharge recovery for two males, corroborating data from Minder against verified activities and events. We recorded semi-structured interviews assessing acceptability. Both participants have similar household set-up, multimorbidity profiles and clinical frailty scores; however, one participant has prior cognitive impairment (PAT1), and one does not (PAT2). Results We present 10 weeks of sleep and activity data from Minder and feedback from interviews. Data observed from PAT1 revealed habitual patterns of activity and sleep. These remained stable, despite discrete clinical events. Conversely, PAT2's data revealed irregular sleep patterns that became increasingly fragmented. Activity was detected in multiple rooms throughout the house at night, consistent with carer reports of night-time wandering. Increased overnight activity coincided with multiple falls, prompting increased care provision. Initial feedback from interviews was the technology helped participants and those involved in their care feel supported. Conclusions As pressure on services mounts, novel approaches to post-discharge care are of increasing importance. Remote healthcare monitoring can provide high temporal resolution data offering ‘real world’ insights into the effects of significant health events in OAs. Our provisional results support our hypothesis that use of this technology is feasible and acceptable for frail, multimorbid participants and highlights the substantial potential of this technology to help clinicians improve community-based care and more effectively monitor interventions and chronic conditions.

Existe música surrealista? Intersecções, cruzamentos, desvios

It took around to two or three years, between 1923 and 1924, for the movement to be fully nominated and characterized by André Breton in his Surrealist Manifest. Many were its artistic ramifications that were being manifested until then, with a special focus on the fine arts and cinema. Nevertheless, whether there is a surrealist music or not there seems to be no critical consensus, which keeps this field of study an ongoing and provisional research matter with provisional results, always open to revision. Being aware of the respective scarce scientific production, we will resort to some authors we were able to identify as having written in a consistent manner about the subject of our choice, with a focus on Theodor Adorno, in alignment with other authors such as Max Paddison, Anne LeBaron and Hannah Lewis who will serve our aim: starting with a contextualization of the movement, we will try to amplify and build a mapping of the surrealist music, although still in a preliminary fashion, by exploring possible definitions and depictions of surrealist music in connection with the philosophic guide-lines that empower the surrealistic thinking and action. The list of the major contributors of this type of music will include names such as Stravinsky, Kurt Weill, Erik Satie, George Antheil, to which we will add, amongst the many others that could be chosen as being the most paradigmatic representatives of this musical revolution, Edgar Varèse, Pierre Schaeffer, and John Cage.

The Relics of the Great War in the Foreground of the Dęblin Fortress as a Basis for the Creation of the Cultural Heritage of the Region

The article presents provisional results of research into material relics of the Great War in the foreground of the Dęblin Fortress. In the years 1914–1915, this area became the arena of battles between the Russian, German, and Austro-Hungarian armies. The hostilities left their mark on the landscape, such as field fortifications, forts, and cemeteries. The aim of the research was to locate and establish the chronology of the remains of field fortifications on the Gniewoszów-Bąkowiec-Mozolice line. The research involved analysis of source materials, LiDAR, field verifications, and analysis of the social value of relics of the Great War. The last phase of the research was analysis of the social value of these objects based on the philosophy of managing the past through preservation and heritage, exemplified by the cemetery in Wysokie Koło and the Gorchakov Fort. The research allowed to determine the course of the main Russian defence line from 1915, which consisted of three groups: Gniewoszów, Bąkowiec, and Mozolice. The best preserved are the remains of field fortifications within the Bąkowiec group, which was the central section of the Russian defence line. As analysis of the social value of the Great War relics indicates, the dominant way is to create heritage, and the message conveyed by the content of places representing the past causes a lot of controversy and conflicts among local residents.

199. TORN Face (Trial of Resorbable Versus Non-Resorbable Sutures in Traumatic Lacerations of the Face). Provisional Results and lessons learned from the 1st trainee-student led RCT

The growth of trainee-led research collaboratives has helped inspire surgical trainees to contribute to evidence based surgical practice. Peer mentoring has allowed surgical trainees to gain invaluable academic experience, and fostered the next generation of the surgeon scientists. We felt that this culture of collaborative research should be extended to include medical students.

Cognitive and neurosensory status as determinants of frailty in the elderly

Cognitive disorders represent an important public health problem due to the high incidence against the background of the aging process and the frailty syndrome, in addition to physical decline, there is a cognitive and neurosensory decline, which causes a decrease of autonomy, limitation of physical performance with impairment of functionality in this group of elderly people. The aim of this study was to evaluate the provisional results of cognitive and neurosensory disorders against the background of the frailty syndrome and to establish some correlations between the determining factors in the elderly. The study, of an epidemiological, descriptive, transversal type, was carried out between November and August 2020 - 2022, on a study group of 400 elderly, average age 72.70±0.30 years, divided into three age groups depending on the Fried frailty screening criteria: group I (frail) – 179 (44,75%) cases, group II (pre-frail) – 115 (28,75%) cases and group III (robust) – 106 (26,5%) cases. Subsequently, all participants were examined according to the complex geriatric assessment (Katz score, Lawton, Tinetti, MMSE, Hamilton), the frailty syndrome was established according to the Fried frailty screening criteria, Gröningen score(GFI), physical performance - The Short Physical Performance Battery(SPPB), sarcopenia - SARC-F, nutritional status - MNA and depression - Geriatric Depression Scale(GDS). The obtained data revealed a high frequency of the frailty syndrome in the elderly, including positive and negative correlations with various geriatric scores, which suggests the type of physical, cognitive and sensory frailty with decreasing autonomy and establishing dependence in the elderly included in the study. This category of population presents a group with increased vulnerability, associated with a physical and cognitive decline.

Reactive surveillance of suicides during the COVID-19 epidemic in France, 2020- March 2022

Abstract Background Mitigation actions during the COVID-19 pandemic, in particular lockdowns and curfews, may impact mental health and suicide in general populations. We aimed to analyse the evolution in suicide deaths from January 2020 to March 2022 in France. Methods Using free-text medical causes in death certificates, we built an algorithm, which aimed to identify suicide deaths. We measured its retrospective performances by comparing suicide deaths identified using the algorithm with deaths which had either an ICD10 code for ‘intentional self-harm’ or for ‘external cause of undetermined intent’ as underlying cause. The number of suicide deaths from January 2020 to November 2021 was then compared with the expected number estimated using a generalized additive model. The analysis was stratified by age group and gender. Analysis from December 2021 to March 2022 was conducted using electronic death certificates only. Results The free-text algorithm demonstrated high performances. From January 2020 to November 2021, suicide mortality declined during France's three lockdowns, particularly in men, and remained quite comparable with expected values between and after both of the country's lockdowns. Provisional results based on electronic death certificates suggest that suicide mortality remained stable until March 2022. Conclusions Monitoring suicide mortality is possible in France with a 4-month delay; this will be reduced to two days when electronic death certification is fully deployed. This study highlighted the absence of an increase in suicide mortality during France's COVID-19 pandemic, and a substantial decline during lockdowns periods, something already observed in other countries. Further studies are required to explain the factors for this decline. Key messages • In the absence of reactive coding of medical causes of deaths, the study proposed an approach to reactively identify suicide based on free-text medical causes from death certificates. • Our findings provide reassurance that the COVID-19 pandemic has not had a negative impact on the general population in terms of suicide in France from March 2020 to September 2021.