Provision Of Explanations Research Articles

Google Gemini and Bard artificial intelligence chatbot performance in ophthalmology knowledge assessment.

With the popularization of ChatGPT (Open AI, San Francisco, California, United States) in recent months, understanding the potential of artificial intelligence (AI) chatbots in a medical context is important. Our study aims to evaluate Google Gemini and Bard's (Google, Mountain View, California, United States) knowledge in ophthalmology. In this study, we evaluated Google Gemini and Bard's performance on EyeQuiz, a platform containing ophthalmology board certification examination practice questions, when used from the United States (US). Accuracy, response length, response time, and provision of explanations were evaluated. Subspecialty-specific performance was noted. A secondary analysis was conducted using Bard from Vietnam, and Gemini from Vietnam, Brazil, and the Netherlands. Overall, Google Gemini and Bard both had accuracies of 71% across 150 text-based multiple-choice questions. The secondary analysis revealed an accuracy of 67% using Bard from Vietnam, with 32 questions (21%) answered differently than when using Bard from the US. Moreover, the Vietnam version of Gemini achieved an accuracy of 74%, with 23 (15%) answered differently than the US version of Gemini. While the Brazil (68%) and Netherlands (65%) versions of Gemini performed slightly worse than the US version, differences in performance across the various country-specific versions of Bard and Gemini were not statistically significant. Google Gemini and Bard had an acceptable performance in responding to ophthalmology board examination practice questions. Subtle variability was noted in the performance of the chatbots across different countries. The chatbots also tended to provide a confident explanation even when providing an incorrect answer.

Development of Biological Science Learning Modules for Class VII SMPN 21 Palu

The instructional resources employed in the educational process at SMP Negeri 21 Palu consisted of teacher’s handbooks and students’ books. Nevertheless, the efficacy of the learning process has been lacking. The students’ learning outcomes were found to be low, particularly in the field of Science, as indicated by the researchers’ observations. The results revealed that the Minimum Completeness Criteria (MCC) for Science was 65. Approximately 55% of the pupils in the class attained standard scores. The utilization of students’ textbooks necessitated the provision of explanations and a teacher’s guide. However, due to time constraints, the students’ learning process was hindered, resulting in instructors being unable to offer optimal explanations and guidance to the students. Therefore, it encompasses the development of novel instructional resources that learners may effectively utilize. One of the available options for students to utilize is the renewal of modules. Science modules have the potential to foster home-based learning among students due to the inclusion of supplementary resources, such as student guides, that facilitate the study of the module content.

Explainable B2B Recommender System for Potential Customer Prediction Using KGAT

The adoption of recommender systems in business-to-business (B2B) can make the management of companies more efficient. Although the importance of recommendation is increasing with the expansion of B2B e-commerce, not enough studies on B2B recommendations have been conducted. Due to several differences between B2B and business-to-consumer (B2C), the B2B recommender system should be defined differently. This paper presents a new perspective on the explainable B2B recommender system using the knowledge graph attention network for recommendation (KGAT). Unlike traditional recommendation systems that suggest products to consumers, this study focuses on recommending potential buyers to sellers. Additionally, the utilization of the KGAT attention mechanisms enables the provision of explanations for each company’s recommendations. The Korea Electronic Taxation System Association provides the Market Transaction Dataset in South Korea, and this research shows how the dataset is utilized in the knowledge graph (KG). The main tasks can be summarized in three points: (i) suggesting the application of an explainable recommender system in B2B for recommending potential customers, (ii) extracting the performance-enhancing features of a knowledge graph, and (iii) enhancing keyword extraction for trading items to improve recommendation performance. We can anticipate providing good insight into the development of the industry via the utilization of the B2B recommendation of potential customer prediction.

Can knowledge based systems be designed to counteract deskilling effects?

Recent calls in the information systems research community argue that we know intelligent systems deskill users, and future research should focus on how to design systems that do not deskill, rather than continue to examine whether the phenomenon occurs. This should be a wakeup call for public accounting firms focused on implementing restrictive audit support systems, which leads to de-skilling of novice accounting professionals. Our research focuses on redesigning knowledge-based systems to facilitate expertise development and counteract the de-skilling effects that result from use of such systems. Specifically, we manipulate the design of the system interface by providing information cues in a screen format consistent with expert knowledge representations and manipulate automatic provision versus voluntary use of explanations for users during task completion. Results show that after using the knowledge-based system to complete a series of reenacted client engagements over a three-day period, both the interface design manipulation and automatic provision of explanations had a positive effect on novice accounting professionals’ development of expert-like knowledge structures. The results of the study have important implications for the development of knowledge-based systems intended to support accounting professionals’ (and other knowledge workers’) expertise development processes.

Pediatrician Explanations of Pediatric Pain in Clinical Settings: A Delicate Craft

Explaining chronic pain to children and families can be challenging, particularly in the absence of an obvious physiologically identifiable cause for the child's pain. In addition to medical intervention, children and families may expect clinicians to provide clarity around the cause of pain. Such explanations are often provided by clinicians who have not received formal pain training. This qualitative study sought to explore the following question: What do pediatricians consider to be important when providing pain explanations to children and their parents? Using semistructured interview methods, 16 UK pediatricians were interviewed regarding their perceptions of explaining chronic pain to children and families in clinical settings. Data were analyzed using inductive reflexive thematic analysis. Analyses generated 3 themes: 1) timing of the explanation, 2) casting a wider net, and 3) tailoring of the narrative. Study findings demonstrated the need for pediatricians to skilfully interpret where children and families are in their pain journey and deliver an appropriate and adaptable explanation relating to individual needs. Analyses identified the importance of providing a pain explanation that could be repeated and understood by others outside the consultation room, to enable children and families to accept the explanation. PerspectiveStudy findings identify the importance of language in addition to familial and broader factors that may influence the provision and adoption of chronic pain explanations provided by pediatricians to children and families. Improving pain explanation provision may influence treatment engagement for children and their parents, subsequently impacting pain related outcomes.

Explanations in Autonomous Driving: A Survey

The automotive industry has witnessed an increasing level of development in the past decades; from manufacturing manually operated vehicles to manufacturing vehicles with a high level of automation. With the recent developments in Artificial Intelligence (AI), automotive companies now employ blackbox AI models to enable vehicles to perceive their environments and make driving decisions with little or no input from a human. With the hope to deploy autonomous vehicles (AV) on a commercial scale, the acceptance of AV by society becomes paramount and may largely depend on their degree of transparency, trustworthiness, and compliance with regulations. The assessment of the compliance of AVs to these acceptance requirements can be facilitated through the provision of explanations for AVs' behaviour. Explainability is therefore seen as an important requirement for AVs. AVs should be able to explain what they have 'seen', done, and might do in environments in which they operate. In this paper, we provide a comprehensive survey of the existing body of work around explainable autonomous driving. First, we open with a motivation for explanations by highlighting and emphasising the importance of transparency, accountability, and trust in AVs; and examining existing regulations and standards related to AVs. Second, we identify and categorise the different stakeholders involved in the development, use, and regulation of AVs and elicit their explanation requirements for AV. Third, we provide a rigorous review of previous work on explanations for the different AV operations (i.e., perception, localisation, planning, control, and system management). Finally, we identify pertinent challenges and provide recommendations, such as a conceptual framework for AV explainability. This survey aims to provide the fundamental knowledge required of researchers who are interested in explainability in AVs.

3Es for AI: Economics, Explanation, Epistemology

This article locates its roots/routes in multiple disciplinary formations and it seeks to advance critical thinking about an aspect of our contemporary socio-technical challenges by bracketing three knowledge formations—artificial intelligence (AI), economics, and epistemology—that have not often been considered together. In doing so, it responds to the growing calls for the necessity of further transdisciplinary engagements that have emanated from work in AI and also from other disciplines. The structure of the argument here is as follows. First, I begin by demonstrating how and why explanation is a problem in AI (“XAI problem”) and what directions are being taken by recent research that draws upon social sciences to address this, noting how there is a conspicuous lack of reference in this literature to economics. Second, I identify and analyze a problem of explanation that has long plagued economics too as a discipline. I show how only a few economists have ever attempted to grapple with this problem and provide their perspectives. Third, I provide an original genealogy of explanation in economics, demonstrating the changing nature of what was meant by an explanation. These systematic changes in consensual understanding of what occurs when something is said to have been “explained”, have reflected the methodological compromises that were rendered necessary to serve different epistemological tensions over time. Lastly, I identify the various relevant historical and conceptual overlaps between economics and AI. I conclude by suggesting that we must pay greater attention to the epistemologies underpinning socio-technical knowledges about the human. The problem of explanation in AI, like the problem of explanation in economics, is perhaps not only, or really, a problem of satisfactory explanation provision alone, but interwoven with questions of competing epistemological and ethical choices and related to the ways in which we choose sociotechnical arrangements and offer consent to be governed by them.

Traditional lectures versus active learning – A false dichotomy?

Traditional lectures are commonly understood to be a teacher-centered mode of instruction where the main aim is a provision of explanations by an educator to the students. Recent literature in higher education overwhelmingly depicts this mode of instruction as inferior compared to the desired student-centered models based on active learning techniques. First, using a four-quadrant model of educational environments, we address common confusion related to a conflation of two prevalent dichotomies by focusing on two key dimensions: (1) the extent to which students are prompted to engage actively and (2) the extent to which expert explanations are provided. Second, using a case study, we describe an evolution of tertiary mathematics education, showing how traditional instruction can still play a valuable role, provided it is suitably embedded in a student-centered course design. We support our argument by analyzing the teaching practice and learning environment in a third-year abstract algebra course through the lens of Stanislas Dehaene's theoretical framework for effective teaching and learning. The framework, comprising 'four pillars of learning', is based on a state-of-the-art conception of how learning can be facilitated according to cognitive science, educational psychology and neuroscience findings. In the case study, we illustrate how, over time, the unit design and the teaching approach have evolved into a learning environment that aligns with the four pillars of learning. We conclude that traditional lectures can and do evolve to optimize learning environments and that the erection of the dichotomy 'traditional instruction versus active learning' is no longer relevant.

Financial reporting transparency, citizens' understanding, and public participation: A survey experiment study

AbstractThis study investigates the conditions under which transparency contributes to citizens' understanding of financial reporting and examines how this enhanced understanding is associated with public participation. To this end, a survey experiment was conducted in which two attributes of financial reporting transparency (i.e., content clarification and presentation format) were the manipulated variables, whereas citizens' understanding and public participation were the outcome variables. Results demonstrate that the provision of explanations to clarify obscure technical jargon does have a positive effect on citizens' understanding. A similar effect was found for the provision of graphical and visual representations. However, the study reveals that there is no additional benefit in simultaneously providing both explanations of technical jargon and visual aids. Furthermore, findings show that the levels of public participation are highest among the individuals who felt they understood the financial information the best, but yet possessed the lowest level of actual understanding.

Can explanations improve applicant reactions towards gamified assessment methods?

AbstractGamification is increasingly being used by organizations in hiring decisions. However, the use of gamification in assessment has advanced quicker than corresponding research. One area in need of research is how applicants' perceptions of fairness are formed when gamified assessments are used in employee selection. Therefore, two studies were conducted to explore the impact of using gamified assessments to applicants' justice perceptions and the role of providing explanations to applicants. Adopting an experimental design to explore organizational justice model in the context of gamified assessments, results indicated that individuals' perceptions of job relatedness are higher when a situational judgment tests (SJT) is used rather than a gamified version, leading to more positive perceptions of procedural fairness and organizational attractiveness (Study 1). The mediating effects of the procedural rules of ease of faking and opportunity to perform were not supported. Subsequently, a 2 × 2 design was used (Study 2) to explore the role of providing explanations. It seems that the provision of explanations on the assessment's faking difficulty generates more positive reactions towards gamified SJTs than text‐based SJTs, in relation to ease of faking and procedural justice, and a spillover effect, invoking favorable reactions to the recruiting organization as well (Study 2).

Genetics education program to help public health nurses improve their knowledge and enhance communities\u2019 genetic literacy: a pilot study

BackgroundAs human genetics knowledge develops, public genetic literacy needs to be increased, though the educational capacity for this purpose has not yet been fully developed. Under this circumstance, the daily work of public health nurses can be viewed as an opportunity to enhance public genetic literacy. However, in Japan, there is not only a lack of public knowledge of human genomics but also a lack of public health nurses’ recognition about genomic literacy. A short-term education program was implemented as a pilot study. This study aimed to examine the effectiveness of the program to support public health nurses’ activity aimed at promoting health services-related genetic literacy.MethodsThe genetics education program was implemented in December 2019, in Kagoshima, Japan. Twenty-three public health nurses cooperated with the research. The program was composed of a case study on consultation, a lecture on hereditary diseases, and a discussion on the role of public health nurses. Familial hypercholesterolemia was used as the topic of the case study. We evaluated scores for cognition, affect, and psychomotor characteristics related to their learning goals before and after the program using Wilcoxon signed-rank tests. Answers in the consultation were qualitatively analyzed.ResultsThe mean cognitive score, capturing provision of explanations of hereditary disease, was 6.3 before the program but increased significantly to 9.3 after the program (p < 0.001). For the affective score, the goal of which was deepening interest in human genetics, the mean score increased significantly from 8.5 before to 11.0 after (p < 0.001). For the psychomotor score, addressing the need for genetic consultation, the mean score increased significantly from 4.4 before to 8.1 after (p < 0.001). Prominent themes extracted from descriptions on the worksheet post training included, “providing advice and accurate information on genetic disorders” and “referral to a specialized organization.”ConclusionsOur findings indicated that this education program helps public health nurses be positively involved in human genetic disorders. Thus, they may connect to their local community to provide accurate genetics knowledge and advice for health management and promoting genetic literacy.

Motion of Particles at the Fundamental Level: NLHV Theory Predictions for a Spiral Gait Locus

Context - The existing literature on particle motion at the fundamental level is sparse. Particles, whether classical or quantum, are assumed to move with a continuous (even if uncertain) velocity. Purpose - The work prospects for a descriptive theory of particle motion from a non-local hidden-variable (NLHV) perspective. This is worth attempting for the potential to better understand fundamental dynamics and kinematics. Method - The new physics provided by the cordus theory was used to infer the mathematical representation of the energisation behaviour of the inner structures, specifically the reactive ends. From this the motion function of the particle as a whole was determined. Findings - In three dimensional space the motion of each reactive end is an irregular spiral displacement locus. The motion comprises a movement phase and a brief immobile phase. This is called a ‘gait’ as it is reminiscent of biological locomotion. Originality - A novel theory of particle motion is offered. The theory predicts that motion comprises a complex spiral locus of the particle. This is unique among theories of physics. Further contributions are the provision of explanations for several physical phenomena: ponderomotive force, the nature of momentum, and bremsstrahlung radiation. Specifically, the theory explains why photon emission would be increasing concentrated in the forward direction with increased electron energy. The theory provides a means to bridge quantum mechanics and special relativity, because it accommodates both particle uncertainty and field transmissions.

Relationship between Patient Characteristics and the Timing of Provision of Explanation about DNAR to Patients with Advanced Lung Cancer.

Objective The aim of the present study was to analyze the relationship between the patient characteristics and the timing of provision of an explanation about “Do Not Attempt Resuscitation (DNAR)” by attending physicians to advanced lung cancer patients. Methods We conducted a retrospective analysis of patients with advanced or postoperative recurrent lung cancer in whom systemic therapy was initiated between 2015 and 2016. Results The data of a total of 74 patients with lung cancer, including 59 patients with non-small cell lung cancer and 15 with small cell lung cancer were analyzed. The median overall survival of the patients was 10.0 months. Records of the explanation about DNAR by the physicians were available for 57 of the 74 (77.0%) patients. For 48 (64.9%) patients, the explanation was provided after the discontinuation of anticancer treatment, and for 9 (12.2%) patients, it was provided during the course of anticancer treatment. The provision of an explanation about DNAR during the course of treatment was associated with a poor performance status at the start of treatment (p=0.028), the tumor histology (p=0.037), the presence of driver gene mutation in the tumor (p=0.029), and shorter survival after the discontinuation of anticancer treatment (p<0.001). Conclusion The results suggested that the timing of provision of an explanation about DNAR was associated with patient characteristics and the predicted prognosis.

A Pragmatic Study of Politeness in Charlotte Bronte's Jane Eyre and Agatha Christie's Murder on the Orient Express

Politeness theory is one of the useful means in interpreting the literary discourse especially fictional discourse where the novelist uses language suitable to the characters moving in the socio-cultural milieu. Therefore, in order to discover a new meaning and eventually arriving at an authentic interpretation of the utterances of the characters, the principles of pragmatics in general and the politeness theory in particular is a novel way of doing so. The present research aims at studying two selected English novels and takes into consideration the politeness strategies as advocated by Brown and Levinson (1987). The researcher chooses to compare two novels written by two female writers to reduce the options and to make the focus only on strategies. If the two novels were one by a male writer and the other by a female , the analysis would have become more complex and necessitated the provision of explanations and justifications that have no room in this study. The researcher chooses two different time periods to clarify whether the environment has changed the way women deal with these strategies or whether they have retained. It is known that politeness strategies have been established because they are the best way to address others without injuring feelings or verbal abuse. But are these strategies actually being used for the reasons cited by Brown and Levinson? Can it not be used to achieve goals and objectives other than what is known about?

Women\u2019s decision-making processes and the influences on their mode of birth following a previous caesarean section in Taiwan: a qualitative study

BackgroundVaginal birth after caesarean (VBAC) is an alternative option for women who have had a previous caesarean section (CS); however, uptake is limited because of concern about the risks of uterine rupture. The aim of this study was to explore women’s decision-making processes and the influences on their mode of birth following a previous CS.MethodsA qualitative approach was used. The research comprised three stages. Stage I consisted of naturalistic observation at 33-34 weeks’ gestation. Stage II involved interviews with pregnant women at 35-37 weeks’ gestation. Stage III consisted of interviews with the same women who were interviewed postnatally, 1 month after birth. The research was conducted in a private medical centre in northern Taiwan. Using a purposive sampling, 21 women and 9 obstetricians were recruited. Data collection involved in-depth interviews, observation and field notes. Constant comparative analysis was employed for data analysis.ResultsEnsuring the safety of mother and baby was the focus of women’s decisions. Women’s decisions-making influences included previous birth experience, concern about the risks of vaginal birth, evaluation of mode of birth, current pregnancy situation, information resources and health insurance. In communicating with obstetricians, some women complied with obstetricians’ recommendations for repeat caesarean section (RCS) without being informed of alternatives. Others used four step decision-making processes that included searching for information, listening to obstetricians’ professional judgement, evaluating alternatives, and making a decision regarding mode of birth. After birth, women reflected on their decisions in three aspects: reflection on birth choices; reflection on factors influencing decisions; and reflection on outcomes of decisions.ConclusionsThe health and wellbeing of mother and baby were the major concerns for women. In response to the decision-making influences, women’s interactions with obstetricians regarding birth choices varied from passive decision-making to shared decision-making. All women have the right to be informed of alternative birthing options. Routine provision of explanations by obstetricians regarding risks associated with alternative birth options, in addition to financial coverage for RCS from National Health Insurance, would assist women’s decision-making. Establishment of a website to provide women with reliable information about birthing options may also assist women’s decision-making.

Interventions to Improve or Maintain Lower-Limb Function Among Ambulatory Adolescents with Cerebral Palsy: A Cross-Sectional Survey of Current Practice in the UK

ABSTRACTObjectives: To describe physiotherapy management to improve or maintain lower-limb function among adolescents with cerebral palsy, classified in Gross Motor Function Classification System levels I–III, in the United Kingdom (UK). Methods: A list of interventions was identified using a nominal group technique and developed into a survey, which was distributed to approximately 2,100 pediatric physiotherapists in the UK through the Association of Pediatric Chartered Physiotherapists and a private physiotherapy clinic in London between April and June 2015. One-hundred and thirty-five physiotherapists completed the survey. Survey respondents indicated how frequently they used each intervention (i.e., “frequently,” “sometimes,” “rarely,” and “never”) in the past year. Results: Provision of explanations to the child, liaison with families, liaison with health professionals, provision of advice to schools, and stretching were the most frequently used interventions with 90%, 90%, 86%, 79%, and 76% of respondents, respectively, reporting that they frequently used each. The interventions most commonly reported as “never” used were conductive education (88%), MOVE programme (85%), functional electrical stimulation (82%), body-weight supported treadmill training (80%), and rebound therapy (71%). Conclusions: This study suggests that a large number of interventions are used by physiotherapists in the United Kingdom to improve or maintain lower-limb function among adolescents with CP, not all of which are evidence-based.

The Experience of Patients During the Clinical Management Pathway of Abdominal Aortic Aneurysms at a NHS Trust.

Background:The epidemiology of abdominal aortic aneurysm (AAA) is changing. Outcomes for aortic surgery have improved. However, the accepted guideline for the management of AAAs has remained unchanged over the last 2 decades. We aimed to gain insight into the patients’ experience while they are managed under the traditional clinical pathway.Method:With the help of a patient focus group, we designed a survey to assess the patients’ perception of the disease and their experience during different stages of the AAA clinical care pathway (surveillance, perioperative care, postoperative follow-up). An invitation to participate in the survey was sent to all patients with AAA who were receiving care at the Oxford Regional Vascular Services Unit, part of the Oxford University Hospitals NHS Trust.Results:We received 194 responses from patients with AAA. One hundred seventy-seven were male, with a median age of 75 to 79 years. Just over a third had undergone surgery already, and the remaining 63% were either in surveillance or awaiting surgery. Their experience during the AAA management pathway was mostly positive. Of the issues that were most important to them in terms of their medical care, the provision of explanation and regularity of monitoring stood out as the most common considerations.Conclusion:Patients are generally satisfied with the care they received, but there is room for improvement. They have also highlighted key areas that are most important to them in terms of their medical care. These should guide the future direction for quality improvement and research.

Understanding parallel structures in public administration

This paper addresses the question of the underlying causes for persistent parallel structures in public administration. Frames like bounded rationality, the budget-maximizing bureaucrat and the political theory of hegemony are examined with respect to the possible provision of explanations for the persistence of parallel administrations. A combination of content analysis and objective hermeneutics is then applied for a case study of parallel administration in Switzerland. A model linking the three approaches is finally developed to show how parallel administration relies on an equilibrium in the struggle for budget and hegemony between the key actors and on ignorance among fringe actors.

Autonomy and dignity of patients with dementia: Perceptions of multicultural caretakers.

A key message in the World Health Organization's report on dementia emphasizes the need to improve public and professional attitudes to dementia and its understanding, while acknowledging the fact that the workforce in dementia care is becoming increasingly diverse culturally. To explore possible differences among formal caretakers from varied cultural background in their attitudes toward the autonomy and human dignity of patients with dementia. Semi-structured interviews and content analysis, utilizing two fictional vignettes for eliciting caretakers' attitudes toward dignity and autonomy of their patients. Participants and context: A total of 20 formal caretakers of patients with dementia from three different cultural groups in Israel ("Sabras," "Arabs," and "Russians"), working in nursing homes and a hospital. Ethical consideration: Approvals of relevant research ethics committees were obtained and followed. In comparison with the other groups, most Arab caretakers offer markedly richer perceptions of human dignity and autonomy. Their human dignity's conceptualization emphasizes "person-centered approach," and their perception of patients' autonomy includes provision of explanations and preservation and encouragement of independence. The differences found in the attitudes toward the meaning of autonomy and human dignity between the Arab caretakers and the other caretakers stand in contrast to previous studies regarding human dignity, emphasizing the common nature of these attitudes. Offering a linkage (theoretical and empirical) between the Arab perceptions of dignity and autonomy, the study strengthen and further the importance attributed in existing literature to person-centered care in enhancing the quality of care for patients with dementia. The conceptualization of human dignity may vary among different cultural groups. It may also influence the extent to which the caretaker holds a full-fledged perception of the patients' autonomy.

Determinants of Cost-Related Nonadherence to Medications among Chronically Ill Patients in Maccabi Healthcare Services, Israel

BackgroundThe effectiveness of value-based insurance design is based on nonadherence, which derives solely from patients’ economic constraints. ObjectiveOur objective was to examine the extent of cost-related nonadherence to chronic medications and to analyze its potential determinants. MethodsWe conducted a telephone survey among a representative sample of Maccabi Healthcare Services chronically ill patients aged 55 years or older (n = 522). We developed a 12-month recall questionnaire that included demographic and socioeconomic characteristics, out-of-pocket expenditure on prescribed medication, physician’s provision of explanation regarding prescribed therapy, adherence, and reasons for nonadherence. Respondents were defined as nonadherent if they reported that they did not purchase prescribed medications in the previous year because of their cost. We applied the multivariable logistic regression model to examine predictors of nonadherence. ResultsMedian (interquartile range) age of the study sample was 69 (13) years (53% males). One hundred sixty-five patients (31.6%) reported not purchasing prescribed medications mainly because of medications’ adverse effects and/or cost. Fifty respondents (9.6%) reported cost-related nonadherence. The multivariable logistic regression model revealed that cost-related nonadherence was associated with respondent’s income lower than 4600 New Israeli shekel (odds ratio [OR] = 10.86; 95% confidence interval [CI] 1.45–81.12), unemployment (OR = 4.32; 95% CI 1.47–12.66), lack of physician explanation about the prescribed medication (OR = 2.38; 95% CI 1.18–4.78), and age (OR = 0.95; 95% CI 0.91–0.99). ConclusionsCost-related nonadherence to chronic pharmaceuticals is self-reported among nearly 10% of the chronically ill patients and is strongly affected by low socioeconomic status, even under universal health insurance coverage and with relatively low co-payments as applied in Israel. Lack of information provided by physicians regarding the therapy is associated with a higher likelihood of cost-related nonadherence.