Health Care Providers Research Articles

Supplementary Feeding (Soy Biscuits) on the Frequency of Nausea and Vomiting of Pregnant Women Experiencing Hyperemesis Gravidarum in Health Crisis Situations

Purpose: This study examines the role of soy biscuits as supplementary food in reducing the frequency and severity of nausea and vomiting in pregnant women experiencing hyperemesis gravidarum (HG) in health crises. The research explores the nutritional effectiveness of soy biscuits, their acceptability among pregnant women, and their potential as a non-pharmacological intervention in community-based maternal healthcare settings, particularly at TPMB Hj Sitti Hasrah Ibrahim. Research Design and Methodology: This study employs a systematic literature review (SLR) approach, analyzing relevant studies from peer-reviewed journals to assess the impact of protein-based nutritional interventions on HG symptoms. The research synthesizes evidence on dietary strategies, maternal nutrition, and the physiological mechanisms through which soy biscuits alleviate HG symptoms. The review also incorporates empirical data from similar interventions to evaluate their feasibility in low-resource and crisis-affected healthcare settings. Findings and Discussion: The findings indicate that soy biscuits significantly stabilize blood sugar levels, reduce gastric motility disturbances, and improve maternal food tolerance. Compared to high-carbohydrate or high-fat diets, protein-based nutrition is more effective in managing nausea and vomiting in HG patients. Additionally, soy biscuits are well-tolerated and accepted by pregnant women, making them a practical intervention for managing HG in settings with limited access to pharmacological treatments. Implications: This study provides practical insights for healthcare providers, policymakers, and food manufacturers by advocating nutritional interventions in maternal healthcare programs. Future research should explore alternative formulations, large-scale implementation, and long-term health outcomes to establish a comprehensive dietary strategy for HG management.

Optimizing healthcare supply chains strategically: analyzing the impact of COVID-19 on pharmaceutical inventory costs through the integration of evidence theory and hybrid evolutionary algorithms

Optimizing healthcare supply chains strategically: analyzing the impact of COVID-19 on pharmaceutical inventory costs through the integration of evidence theory and hybrid evolutionary algorithms

A qualitative study on the psycho-oncological experiences of women navigating breast cancer diagnosis, treatment, and survivorship in Ethiopia.

To understand the lived experiences of Ethiopian women who self-identify as breast cancer survivors, particularly facilitators, and barriers to engaging with care in biomedical settings. Between November 2022 and January 2023, six focus group discussions were conducted in Amharic with 44 breast cancer patients and survivors in Adama, Ethiopia, stratified based on HIV status and participation in available peer support groups at their treatment hospital. Thematic analysis was conducted, with methodology reported in accordance with the Consolidated Criteria for Reporting Qualitative research checklist. Our analysis identified four key areas along the continuum of care: (1) recognition of BC-related symptoms, (2) seeking clinical care for BC symptoms, (3) adherence to BC treatment plans, and (4) coping strategies during ongoing care. Known facilitators for engagement in BC care included health education programming as well as emotional and financial support from loved ones and fellow survivors. However, participants described several barriers to clinical care such as the perception that BC is a death sentence, conflict between spiritual/traditional and clinical approaches to care, and fragmentation of care across multiple health facilities and providers. Based on some of the identified barriers to care, future efforts to enhance cancer care in Ethiopian settings should consider national awareness campaigns for BC to dispel local myths and misconception about BC, formal partnerships between faith-based community leaders and health care providers, and the use of family- and community-centered models of cancer care in biomedical settings. Recognition of psycho-oncological challenges to accessing clinical care for BC and providing opportunities for peer support and positive spirituality to navigate these challenges may improve patients' experiences in the Ethiopian biomedical system and reduce the potential negative experiences of future patients.

Financing Universal Healthcare Coverage in Nigeria Through the Basic Health Care Provision Fund: Challenges and Potential Solutions.

This study examines the Nigerian government's efforts to provide Universal Health Care (UHC) and reduce out-of-pocket spending through the Basic Health Care Provision Funds (BHCPF) scheme. The study gathered insights into the degree of UHC accomplishment through the implementation of the BHCPF using qualitative and quantitative secondary data analysis approaches, which combined a series of interviews with Statista data. The findings show that BHCPF implementation must be better aligned with the needs of healthcare recipients, particularly at the local government level, with poor infrastructure, insufficient funding, a lack of workforce, limited medicine, low awareness, and reachability identified as key factors making the scheme inaccessible. For immediate improvement, supported by Statista data, the study recommended telemedicine to address some of the challenges of reachability/accessibility because it represents an advantageous approach, given its significant contribution to the expansion of healthcare accessibility and the mitigation of health inequities in under-resourced countries around the world. Furthermore, the Public-Private Partnership method backed by desk-based research method was deemed ideal for addressing health care infrastructure provisioning challenge. Overall, this study demonstrates, on the one hand, the difficulty in improving access to care at the local government level, given the multifaceted and complex nature of the barriers to care for low-income people; and on the other, the urgent need for more holistic collective action to improve quality healthcare services for all in Nigeria.

Prostate cancer screening in the Middle East and North Africa: a cross-sectional study on current practices.

Prostate cancer is a significant health concern in the Middle East and North Africa (MENA), with many cases diagnosed at advanced stages, a high mortality-to-incidence ratio, and low prostate cancer awareness. This study aims to evaluate prostate cancer screening practices in the region to inform effective early detection and management strategies. A cross-sectional survey was conducted from July 1, 2023, to November 8, 2024, among physicians from 19 countries in the MENA region. The study utilized a validated questionnaire to assess prostate cancer screening practices, barriers, and educational needs. The survey had a response rate of 96.8%, with 1,163 participants. Of these, 34.7% routinely performed prostate cancer screenings, with 61.1% using PSA tests. The primary barrier was lack of patient awareness (51.2%). Additionally, 65.3% of participants had no formal training. To improve screening rates, participants suggested better patient education (63.5%), increased training for healthcare providers (41.9%), and improved access to screening equipment (38.9%). This study reveals that prostate cancer screening was low, with barriers including a lack of patient awareness and formal training among physicians. Addressing these issues through culturally tailored education programs may improve early detection rates and ultimately reduce the burden of prostate cancer in the MENA region.

Impact of Systems of Care on Emotional Well-Being of Primary Family Caregivers of Children with Medical Complexity.

This study aimed to explore the experiences of caregivers of children with medical complexity (CMC) enrolled in a complex care program, focusing on their interactions with the healthcare system and the impact on caregiver well-being. Qualitative interviews were conducted with 20 caregivers, and data were analyzed using interpretative phenomenological analysis. The interviews covered topics such as navigating the medical system, accessing resources, and interactions with healthcare providers. Caregivers faced challenges in navigating the healthcare system, including scheduling appointments, finding suitable treatment plans, and managing hospitalizations. They expressed the need for more practical, financial, and informational resources to support their caregiving responsibilities. Access to respite care was identified as a significant challenge, with limited availability and affordability. Caregivers highlighted the importance of connecting with other caregivers and accessing accurate information specific to their child's condition. The findings emphasize the unmet needs of caregivers of CMC and the barriers they face within the healthcare system. To support caregiver well-being, interventions should address these barriers by improving infrastructural support, enhancing training for in-home caregivers, and advocating for comprehensive support services for the entire family. Involving caregivers in the development and implementation of interventions is crucial to ensure their feasibility, applicability, and desirability. By addressing these challenges and tailoring interventions to the unique needs of caregivers of CMC, healthcare providers can promote better outcomes for both caregivers and their CMC.

Understanding Patient-Provider Relationships: A Qualitative Study of Rural HIV Care in a Low-Prevalence Mountain West State in the United States.

Supportive relationships between people living with HIV (PLWH) and their health care providers are crucial for treatment adherence and communication about health needs. This study explored key elements of patient-provider relationships (PPRs) among PLWH in a predominantly rural, Mountain West state with a low HIV prevalence. We analyzed in-depth interviews conducted with 17 PLWH. We identified 4 key themes related to PPR: (a) providers' limited competencies in HIV and lesbian, gay, bisexual, transgender and queer issues, (b) patients' desire for empathetic and nonjudgmental care, (c) patients' experiences of dismissal or dehumanization by providers or the health care system, and (d) experiences and fear of stigma. Our findings underscore the role that PPR plays in addressing or exacerbating barriers for PLWH in rural areas, emphasizing the need for both interpersonal (e.g., provider-focused) and structural interventions to increase providers' HIV knowledge, decrease stigma, and foster positive PPR.

Nutritional knowledge and practices of low-income women during pregnancy: a qualitative study in two Oaxacan cities

BackgroundAdequate dietary intake is critical for healthy pregnancies. Recent changes in social services in Mexico, coupled with high levels of food insecurity, call into question whether expecting women of the lowest socioeconomic status are able to meet their dietary and nutritional needs in this changing context. The aim of this study was to explore the nutritional practices, education and received and employed among women during their pregnancy.MethodsGuided by Ecological Systems Theory and an Intersectionality Framework, this qualitative study was carried out in Oaxaca City and Puerto Escondido, in Oaxaca, a Mexican state with high levels of food insecurity. Women who had at least one child in the past five years and had lived in Oaxaca for the past five years were eligible to participate. Twenty-five women participated in semi-structured in-depth interviews conducted between June and December of 2023. A grounded theory approach was used for coding. NVivo was used for coding and analyses.ResultsFive key themes emerged linked to individual-level characteristics and the multiple social identities related to the social support for nutritional knowledge and practices among low-income Oaxacan women during pregnancy: (1) Life experiences, sociodemographic, and health characteristics that influence nutritional practices and knowledge during pregnancy; (2) Female family members as a primary source of nutritional knowledge and food support; (3) Support from other members of women’s social networks; (4) Medical guidance for nutrition during pregnancy; and (5) Quality and gaps in the broader health care system and social services. These themes highlight how women’s own experiences and social identities and the different interpersonal and community-level environments, particularly those of mothers and grandmothers and health care providers, interact and shape women’s nutritional knowledge and practices, such as foods and nutritional supplements consumed, during pregnancy.ConclusionNutritional knowledge and practices during pregnancy are impacted by multiple social identities women have and different factors at the individual, group, and structural level. Future multi-level approaches in research and programming that take into consideration the individual, family members, and other social influences are needed to address the gaps in nutrition that women in Oaxaca go through during the prenatal period.

Evidence Gathering and Recommendation Building Procedures for Position Statements: New Methodology.

Position statements are utilized by healthcare organizations to summarize evidence and clearly articulate consensus on best practices. The procedures for developing position statements by the National Athletic Trainers' Association and the NATA Research and Education Foundation have been updated to enhance transparency, reduce bias, and better incorporate the available research to support clinical care recommendations. The paper details the processes of topic selection, author group formation, evidence gathering, and recommendation building, emphasizing the systematic approach and the inclusion of diverse expertise. These changes ensure that future position statements, starting from June 2024, will be more rigorously developed and serve as a reliable resource for athletic trainers, other healthcare providers, and important stakeholders in various settings.

How to Use Virtual Reality from Echocardiographic-Acquired Images.

Our goal of this review is to describe the current evidence and future applications of virtual reality (VR) from echocardiographic acquired images to enhance diagnostic accuracy and improve the visualization of cardiac structures by providing immersive 3-dimensional (3D) environments for better interpretation, communication between healthcare providers, families and trainees. Virtual reality is a powerful tool for education, procedural planning and simulation. Using readily available echocardiographic images for this purpose is feasible, effective and safe. This document highlights the increasing role of VR in procedural planning, education, and intraprocedural guidance using three-dimensional echocardiography (3DE). Key advancements include the development of smaller 3D transthoracic and pediatric transesophageal probes with better temporal resolution, which enable enhanced imaging for preoperative planning. VR allows surgeons to visualize dynamic 3D cardiac models created from echocardiographic or Computed Tomography (CT) data, enabling better pre-surgical rehearsal, device selection, and landing zone visualization. It also provides immersive training tools for echocardiographers and offers potential for intraprocedural guidance in interventions such as atrial septal defect closures. These developments underscore the growing synergy between VR and 3DE for refining diagnosis and procedural strategies.

Midwives’ knowledge and perspectives on neonatal resuscitation and survival before and after Helping Babies Breathe training: a qualitative study in Uganda

ObjectivesBirth asphyxia is a significant factor contributing to neonatal mortality, particularly in low- and middle-income countries where most neonatal deaths occur. Encouraging women to deliver in hospitals has become a...

Long-term risk of endometrial cancer after assisted reproductive technology.

What is the risk of endometrial cancer after long-term follow-up in women treated with ART between 1983 and 2001 compared with women in the general population and subfertile women who did not undergo ART? The risk of endometrial cancer is not increased in women who underwent ART in the Netherlands between 1983 and 2001, neither compared with women from the general population nor compared with subfertile women not treated with ART. Concerns have been raised that subfertility treatment may be associated with increased risk of endometrial cancer. However, published studies show inconsistent results regarding the effects of ovarian stimulation and specific subfertility diagnoses on endometrial cancer risk. A nationwide historic cohort study (the OMEGA-cohort) was conducted to examine the risk of cancer in women after ovarian stimulation for ART. The OMEGA-cohort comprises 30625 women who received ovarian stimulation for ART (ART group) in 1983-2000 and 9988 subfertile women not treated with ART (non-ART group). After a median follow-up of 24 years, endometrial cancer incidence was ascertained through linkage with the Netherlands Cancer Registry. Endometrial cancer risk in the cohort was compared with that in the general population using person-years analyses, and between the ART group and non-ART group using multivariable Cox regression analyses. Detailed ART-treatment data were obtained from the medical records and complete information on parity and age at first birth was obtained through linkage with the Personal Records Database. Information on hysterectomy and endometriosis was collected through linkage with the Dutch Nationwide Pathology Databank (Palga). Data about lifestyle factors, including BMI, were obtained through a self-administered questionnaire. After a median follow-up duration of 24 years, 137 endometrial cancers were diagnosed. Endometrial cancer risk after ART was not significantly increased compared with that in the general population (standardized incidence ratio = 1.19; 95% CI = 0.97-1.44) nor compared with that in the non-ART group (multivariably adjusted hazard ratio = 1.11; 95% CI = 0.74-1.67). Risk of endometrial cancer did not increase with longer follow-up or with more ART cycles, and the risk within the cohort, did not vary by cause of subfertility (male, tubal, unexplained, and other). Irrespective of ART treatment, endometrial cancer risk was increased in obese women and women with endometriosis, but decreased among parous women and women who used oral contraceptives. Although the findings of the study are reassuring, the median age of the women at the end of follow-up (median age 56 years) was still rather young. Therefore, there is a need for at least 10-15 additional follow-up years to draw definitive conclusions. In addition, other large studies are needed to investigate the risk of endometrial cancer in women who underwent ART. The results of this study contribute to knowledge about long-term health after ART treatment, which is valuable to subfertile couples, considering or undergoing fertility treatments, and their healthcare providers. This study was supported by a grant from the Dutch Cancer Society (NKI 2006-3631) and a departmental grant from the Department of Obstetrics and Gynecology of Erasmus Medical Center, Rotterdam, the Netherlands (2011-019). Ma.S. is Associate Editor of Human Reproduction Open; A.W.vd.B.-D received support for attending meetings and/or travel from the Dutch Cancer Society; C.B.L. is Editor-in-Chief of Human Reproduction; A.E.P.C. is Associate Editor of Human Reproduction Update, received royalties from Uptodate Hyperthecosis, and participated at the Data Safety Monitoring Board of the DSMB POEM Study; F.B. has received research support from Merck, honoraria or consultation fees from Merck Healthcare KGaA, Bensis Healthcare, CooperSurgical, and participated in an advisory board for Merck and Ferring; J.L. has received research support from Ferring, Merck, and Roche Diagnostics, consulting fees and honoraria from Ferring, participated on a Data Safety Monitoring Board or Advisory Board of the LOCI trial, is President of the AE-PCOS society, and Member of the ASRM Integrity Committee; J.M.J.S. has received honoraria from Ferring and Merck, support for attending meetings and/or travel from Ferring, Merck, and Good Life, and participated in the advisory board of Merck; L.L.v.L. received support for attending meetings and/or travel from Olympus Medical Expert training; M.M.v.R. received support for attending meetings and/or travel from Ferring; M.G. declares departmental research and educational grants from Ferring (location VUmc), unrelated to the presented work. The other authors declare no competing interests. N/A.

Delays in Immediate Athletic Training Evaluation Following Concussion Among High School Football Players: A Report from the Athletic Training Practice-Based Research Network.

Context: Football is the most popular sport among high school boys in the United States. Concussion risk is elevated in the sport due to the high degree of physical contact. Healthcare providers are more likely to be present at the time of concussion during games and for varsity-level athletes, but how time to an immediate athletic trainer (AT) evaluation varies between sport levels and injury settings has yet to be investigated.Objective: Investigate associations between athlete sport level, injury setting, and same day AT evaluation among high school football players following a concussion. Design: Cross-sectional study.Setting: Retrospective analysis of de-identified patient records created within the Athletic Training Practice-Based Research Network.Patients: Patients evaluated and diagnosed with a concussion during in-season high school football participation from 2010-2023. Main outcome measure: Sport level (freshman, junior varsity [JV], varsity), injury setting (game, practice), and same-day evaluation following concussion (yes, no). Results: 1,260 patient cases were included in analysis. A significant association was found between sport level and same-day evaluation (p=0.02), and between injury setting and same-day evaluation (p<.001). A higher percentage of patients playing at the varsity level were evaluated the same day as their injury compared to those playing at the JV and freshman levels. Additionally, a higher percentage of football athletes were evaluated the same day if they sustained an injury during an in-season practice compared to a game. These associations remained significant after stratifying by sport level for freshman (p=0.01) and JV (p<.001) athletes, but not for varsity athletes (p=0.61).Conclusions: Freshman and JV football athletes, as well as those injured during games, are less likely to receive a same-day evaluation by an AT after concussion. Timely care improves recovery following concussion, emphasizing the need for equitable access to immediate care across sport levels and settings.

Neurocritical Care Organization in the Low-Income and Middle-Income Countries.

This study aimed to assess the organization, infrastructure, workforce, and adherence to protocols in neurocritical care across low- and middle-income countries (LMICs), with the goal of identifying key gaps and opportunities for improvement. We conducted a cross-sectional survey of 408 health care providers from 42 LMICs. The survey collected data on the presence of dedicated neurointensive care units, workforce composition, access to critical care technologies, and adherence to evidence-based protocols. Data were analyzed using descriptive statistics, and comparisons were made across different geographical regions (East Asia and the Pacific, Europe and Central Asia, Latin America and the Caribbean, the Middle East and North Africa, and South Asia and sub-Saharan Africa) and economic strata [low-income countries (LICs), lower middle-income countries (LoMICs), and upper middle-income countries (UMICs)]. Only 36.8% of respondents reported access to dedicated neurointensive care units: highest in the Middle East (100%), lowest in sub-Saharan Africa (11.5%), highest in LoMICs (42%), and lowest in LICs (13%). Access to critical care technologies, such as portable computed tomography scanners (9.3%; UMICs 11%, LICs 0%) and tele-intensive care unit services (14.9%; UMICs 19%, LICs 10%), was limited. Workforce shortages were evident, with many institutions relying on anesthesia residents for 24-h care. Adherence to protocols, including those for acute ischemic stroke (61.7%) and traumatic brain injury (55.6%), was highest in Latin America and the Caribbean (72% and 73%, respectively) and higher in UMICs (66% and 60%, respectively) but remained low in LICs (22% and 32%, respectively). The study highlights critical gaps in infrastructure, workforce, and technology across LMICs, yet it also underscores the potential for improvement. Strategic investments in neurointensive care unit capacity, workforce development, and affordable technologies are an unmet need in resource-limited settings. These findings offer a road map for policymakers and global health stakeholders to prioritize neurocritical care and reduce the disparities in patient outcomes globally.

IQ Survey Results on Current Industry Practices: Part 2-Quantitative Evaluations of Immunogenicity Assessment.

All biotherapeutics have the potential to induce an immunogenic response and generate anti-drug antibodies (ADAs), especially when administered as multiple doses over prolonged periods. However, a clinically meaningful effect of ADAs can be difficult to identify to communicate the impact of immunogenicity on drug exposure, safety and efficacy outcomes in product labels in a way that is useful for health care providers. The immunogenicity working Group, IQ Consortium (Clinical Pharmacology Leadership Group) has conducted a survey to understand the current practices in analyzing immunogenicity data generated during clinical development and its impact on pharmacokinetics, clinically relevant pharmacodynamic biomarkers, safety, and efficacy outcome measures. Information was collected for 93 drugs, spanning multiple drug classes and over the different phases of clinical development, including post-approval. The predominant drug classes reported included monoclonal antibodies or Fc-fusion proteins, endogenous protein replacement therapies, bispecific antibodies, and antibody-drug conjugates. The extent of quantitative evaluation varied and was influenced by several factors, including descriptive analyses, statistical approaches, and modeling. In addition to understanding current practices, this survey also highlights areas for future exploration in analyzing clinical relevance of ADAs which can facilitate the use for regulatory submissions and product labels.

Does Social Health Insurance Influence Cognitive Impairments Among Older People? Evidence from Longitudinal Surveys in South Korea and China.

Significant differences exist in the coverage and target population of social health insurance between South Korea and China. This study investigated the effects of different types of social health insurance on cognition trajectories and survival of older people with cognitive impairments. Data were drawn from the Korean Longitudinal Study of Aging (N = 1812) and the Chinese Longitudinal Healthy Longevity Survey (N = 1168) from 2008 to 2018. Growth mixture models were built to identify cognition trajectories. Logistic regression and Cox proportional hazards models were performed to identify risk factors. Results indicate that although social health insurance improved overall health outcomes among older people with cognitive impairments, there were significant socioeconomic inequalities in its protective influence. Results suggest that South Korea's Medical Aid and China's Basic Medical Health Scheme showed positive influences on cognition trajectories among illiterate older people. In contrast, results indicate that, in China, older adults with cognitive impairments from higher socioeconomic backgrounds benefited more from social health insurance in terms of cognition trajectories and survival. This study urges governments to consider expanding healthcare provision to protect the most vulnerable older people with cognitive impairments in general and those from low socioeconomic backgrounds in particular.

The impact of environmental changes on infectious diseases among children in North America.

Climate change is no longer a distant threat but a present and accelerating force reshaping the epidemiology of infectious diseases in North America and elsewhere. Rising temperatures, shifting precipitation patterns, and extreme weather events are impacting the geographic distribution of pathogens and their vectors. Understanding these environmental influences on infectious diseases in children is essential for equipping healthcare providers to deliver competent care in the era of climate change. The northward spread of vector-borne diseases, warming waters and soils, and disease outbreaks following extreme weather events highlight the complex and multifactorial ways through which the environment influences the spread of infectious diseases. Continuing medical education and training on the evolving epidemiology of climate-sensitive diseases is critical for clinicians to address emerging health threats effectively. We advocate for more equitable funding and resource allocation to support innovative pediatric research on climate change and infectious diseases in the United States and other countries in North America.

Sustainable healthcare supply chains with telemedicine: price and service rate decisions

Sustainable healthcare supply chains with telemedicine: price and service rate decisions

Barriers to Providing Optimal Care in Idaho from the Perspective of Healthcare Providers: A Descriptive Analysis

Background/Objectives: Few studies have assessed barriers to providing care from the perspective of interprofessional healthcare providers. Despite Idaho’s predominantly rural geography, limited research exists assessing barriers to providing care within the state. This study sought to assess barriers to providing optimal healthcare using a sample of 400 healthcare providers at 22 clinic sites across the state. Methods: A barriers to providing optimal care 9-factor, 41-item survey was modified from an existing survey. Healthcare providers rated barrier items using an 11-point Likert scale. The survey was distributed to a convenience sample of healthcare providers in 22 different clinic sites in rural Idaho. Results: Four hundred interprofessional healthcare providers in Idaho across 13 professional disciplines completed surveys. Items in the Service Access (mean = 7.14), Patient Complexity (mean = 6.59), and Resource Limitations (mean = 6.18) factors were reported as the most commonly perceived barriers to providing optimal care. Conclusions: Few studies have assessed rural interprofessional providers’ perceived barriers to providing optimal, high-quality, care, specifically in the rural state of Idaho, where healthcare services are often not equitable compared to urban regions. The results suggest that commonly perceived barriers exist throughout the state, particularly Service Access, Patient Complexity, and Resource Limitations. Further research is needed to develop data-driven decisions to address these concerns.

Endometriosis influencers on Instagram: Who are they and what are they posting?

To examine endometriosis-related content on Instagram, a platform increasingly used for health communication, to understand: 1) the identity of Instagram content creators; 2) themes, tones, and emotions evoked from posts; and 3) accuracy of educational information. The relevance of this study lies in its potential to inform healthcare providers on how to better engage with social media to support individuals with endometriosis. This mixed methods cross-sectional observational study was performed on June 6, 2021. Instagram content was collected via two approaches: 1) searching hashtags related to endometriosis from a list of 30 hashtags and analyzing the top 20 and 10 most recent posts and 2) searching endometriosis-related terms under accounts to examine the first 30 accounts retrieved. Posts were categorized into themes and evaluated for tone and emotion, with educational posts also evaluated for accuracy. Publicly available data on Instagram. None INTERVENTIONS: None MEASUREMENTS AND MAIN RESULTS: The study analyzed 768 Instagram posts and 228 accounts. Of these, 59.9% of posts and 92.1% of accounts contained endometriosis-related content. Most posts (55.4%) and accounts (59.0%) were authored by people with endometriosis. Accounts owned by people with endometriosis were significantly more active and had more followers compared to those who identified as healthcare providers (mean difference of total # of posts=714.4, P<0.001, mean difference of total # of followers = 27,194.7, P<0.001, respectively). Social support was the most common theme (67.2%). Many posts had a negative tone (43.7%) and evoked sadness (57.6%). Objective educational posts contained 85.0% accurate information. Allied healthcare providers were most likely to post accurate educational information compared to all other content creators (P<0.001). Instagram is widely used by people with endometriosis, with posts predominantly centered around social support and personal narratives. Healthcare providers can use this information better understand the experiences of people with endometriosis, and to engage more effectively on Instagram.