A tree-core sample (Aspidosperma obscurinervium, popular name: “pequiá marfim”) about 161 years old (cut in 1990), from the Ducke Reserve at the Amazon Basin, Manaus, Brazil was analyzed by PIXE (Particle Induced X-ray Emission) and proton backscattering in 136 different spots along its life. Twenty-two elements plus the density of the wood were measured (C, O, H, Al, Si, P, S, Cl, K, Ca, Ti, Cr, Mn, Fe, Ni, Cu, Zn, Sr, Co, Rb, W and Pb). Average C, O, and H results (49.77%±0.15%, 44.29%±0.14% and 5.95%±0.12%, respectively) compare well with literature values for the biomass in the Amazon region. The variability of trace elements along the tree rings showed important features that could be caused by modifications in the environment during the life of the tree. The well behaved variability of some trace elements (like K, P, Mn, Ca, etc.) seems to reflect the physiological response of the tree to external changes in the environment. The concentration of K varied from about 4 up to 2000 ppm in a given period of the life of the tree. The same period also shows important changes in the bulk composition and structure of the rings (e.g. C and density series). Multivariate statistical methods (cluster and factor analyses) were used for data interpretation, helping in the separation of periods of important transformations in the tree. The elemental time series is compared with historical records of regional development and with some global events that could possibly affect the tree. The period of maximum variation in the elemental concentrations appears to be related to the Brazilian rubber boom (1859–1912), responsible for several transformations in the Amazon region. In particular in the Manaus region, large development has occurred in the beginning of the 20th century, which are reflected in the results of this tree-core analysis.