Background: Liver function assessment is very important in clinical practice. The possibility of using magnetic resonance imaging (MRI) as a method for anatomical and functional evaluation of the liver represents actual for clinical practice. Aims: This study aims to examine the possibility of using hepatobiliary contrast-enhanced MRI for evaluation of liver function. Materials and methods: Datasets of patients who underwent gadoxetic acid-enhanced MRI were retrospectively reviewed. The patients were divided into 2 groups: first one included patients with impaired liver function and the second one with normal liver function. Basing on MRI in hepatobiliary phase the following indexes were estimated: liver parenchyma signal intensity (LSI), ratio of LSI to spleen signal intensity (LSI/SSI) and ratio of LSI to portal vein signal intensity (LSI/VSI). Differences among these parameters were compared between groups. Correlation analysis was used to evaluate the correlation between LSI and laboratory blood tests reflecting liver function (total bilirubin (TB), albumen, aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), gamma glutamyl transpeptidase (GGT), prothrombin time (PT)). Results: Datasets of 53 patients (25 men and 28 women, aged 24 to 84 years) were analyzed. The first group included 19 people, the second – 34 people. Median of LSI was 919.05 [669.65;1258.35] in the first group and 1525.13 [1460.5;1631.4] in the second one (p=0.0000001), Median of LSI/SSI was 1.2 [1.04;1.7] in the first group and 1.7 [1.46;1.96] in the second one (p=0.00076). Median of LSI/VSI was 1.44 [1.29;1.83] in the first group and 1.6 [1.43;1.83] in the second one (p=0.1). Correlation between LSI and blood tests parameters (total bilirubin (r=-0.61; p=0.000001), albumen (r=0,13; p=0,61), AST (r=-0.57; p=0.000009), ALT (r= -0.44; p=0.001), ALP (r=-0.45; p=0.0007), GGT (r=-0.5; p=0.0003), PT (r=-0.34 ; p=0.04)) was estimated. Conclusions: The study reflects the ability to assess liver function using indices (LSI and LSI/SSI) derived from gadoxetic acid-enhanced MRI. This study did not confirm the assumption of the effectiveness of using the LSI/VSI index to evaluate liver function. A statistically significant inverse correlation was identified between LSI and blood tests parameters reflecting liver function, except albumen. The results indicate the possibility of MR-assessment of liver function.