The sand fixation ecosystem services and human activities on the Qinghai–Tibet Plateau (QTP) play a crucial role in local sustainable development and ecosystem health, with significant implications for surrounding regions and the global ecological environment. We employed an improved integrated wind erosion modeling system (IWEMS) model for the QTP to simulate sand fixation quantities under the unique low temperature and low pressure conditions prevalent on the plateau. Using the human footprint index (HFI), the intensity of human activities on the plateau was quantified. Additionally, an econometric model was constructed to analyze the impacts of the natural factors, the HFI, and policy factors on the sand fixation capacity. The results revealed that the average sand fixation quantity was 1368.0 t/km2/a, with a standard deviation of 1725.4 t/km2/a, and the highest value during the study period occurred in 2003. The average value of the HFI for 2020 was 6.69 with a standard deviation of 6.61, and the HFI exhibited a continuous growth trend from 2000 to 2020. Despite this growth, the average human activity intensity remained at a low level, with over 50 % of the area having an index value of <4.84. Overall, a strong negative correlation was observed between the sand fixation ecological capacity and the HFI on the QTP. However, extensive regions exhibited high values or low values for both indicators. The sand fixation capacity on the QTP is influenced by both natural and human factors. In light of these findings, suggestions are made for optimizing protected area design, rational control of human activity scales, and targeted human activity aggregation within certain regions as part of ecological conservation strategies. This study has implications for assessing sand fixation ecological functions in high-altitude regions and enhancing sand fixation capacity within the region, providing valuable practical guidance.
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