Prosthesis Side Research Articles

The effect of femoral prosthesis design on patellofemoral contact stresses in total knee arthroplasty: a case–control study with mid-term follow-up minimum 3-year follow-up

BackgroundTo investigate the differences in postoperative patellofemoral pressures and patellar tracking during at least three years of follow-up in patients using three prostheses of different designs in total knee arthroplasty (TKA) without patellar resurfacing.Methods: Radiographic investigationsThe study included 401 patients who had a total of 480 knee prostheses implanted without patellar resurfacing. The prostheses used were Genesis II (external rotation design of femoral prosthesis), Triathlon (design with deep trochlear grooves), and Gemini MK II (deepening of trochlear groove and lateral condylar protrusion that closely follows the anatomical shape). The patients' patellar tracking was assessed by measuring patellar tilt and displacement during postoperative follow-up. Furthermore, postoperative knee function and pain were evaluated through range of motion, Knee Society scores (KSS), and Forgotten Joint Score (FJS) to compare the different groups.Finite element analysisConstructing a finite element model of the knee joint of a normal volunteer after total knee arthroplasty using different prostheses for nonpatellar replacement. The three models' von Mises stress distribution heat map, peak contact pressure, and patellar transverse displacement were compared at 30°, 60°, and 90°, respectively.Results: Radiographic investigationsA total of 456 knees of 384 patients were investigated at a 3-year follow-up after TKA without patellar resurfacing. There were no significant differences in patellar tracking between the three groups. Patients with all three prostheses demonstrated favorable clinical outcomes at 3 years postoperatively, with no statistically significant differences in knee scores (91.9 vs 92.3 vs 91.8) or range of motion (127.9° vs 128.5° vs 127.7°) between the groups. However, there was a significant difference between Genesis II and Gemini MK II in the Forgotten Joint Score (59.7 vs 62.4). Patients with persistent postoperative anterior knee pain were present in all three groups (16 vs 12 vs 10), but the incidence was not significantly different.Finite element analysisThe von Mises stress distribution heat map showed that during flexion, the patellofemoral stresses were mainly concentrated on the lateral side of the prosthesis side, and the contact site gradually shifted downward with increasing flexion angle. At the same time, the peak contact stress of the patellofemoral joint increased with the gradual increase in the flexion angle. Genesis II, with a wider and shallower trochlear groove, showed greater patellofemoral stresses and lateral patellar displacement after TKA without patellar resurfacing. The Gemini MK II with a deeper trochlear groove and slightly protruding lateral condyle is more in line with anatomical design, with smaller patellofemoral joint pressure and better patellar tracking.ConclusionsIn TKA without patellar resurfacing, a prosthesis with a deeper trochlear groove, a slightly higher lateral femoral condyle, and a more anatomically designed knee that better matches the patellar morphology should be a better choice.

A Feasibility Study of Piecewise Phase Variable Based on Variable Toe-Off for the Powered Prosthesis Control: A Case Study

To achieve stable walking and provide proper assistance, it is crucial to have synchronized control of the prosthesis, treating the user and the prosthesis as a coupled system. Additionally, speed adaptability is important for controlling the prosthesis at different walking speeds. One approach to achieving this is by using a phase variable to estimate the user's gait phase and control the prosthesis in synchrony with the user. However, the current phase variable (i.e., PV) cannot reflect variable toe-off timing at different speeds, although individuals have different toe-off timings per walking speed. To address this issue, we propose a piecewise phase variable (i.e., PW-PV) that can be adjusted for different toe-off timings while estimating the user's gait phase at various walking speeds. As a case study, we conducted a treadmill walking experiment with two participants (i.e., one healthy and one amputee) using a custom-built powered prosthesis. We collected and analyzed joint kinematics, kinetics, and ground reaction force data to validate the feasibility of the PW-PV. The use of the PW-PV resulted in both participants experiencing faster load transfer and a more natural rollover while walking. This allowed healthy and amputee participants to walk with longer push-off durations of 10.6% and 15.2%, respectively, and greater ankle push-off work of 7.3% and 16.9%. Furthermore, with the PW-PV, the amputee participant demonstrated higher vertical ground reaction forces of 5.4% and 4.7% on her prosthesis side leg during load acceptance and push-off periods, potentially suggesting increased confidence in using the prosthesis. We anticipate that by using the proposed phase variable, we will be able to provide more appropriate and timely assistance to individuals at variable walking speeds.

Results of surgical treatment and rehabilitation of patients with post-traumatic subatrophy and anophthalmic syndrome in combination with bone deformities of the orbit

BACKGROUND: Ocular prosthetics remains an important and actual task in the rehabilitation of patients with anophthalmos of various origins.
 AIM: To increase the effectiveness of cosmetic prosthetics in patients at the formation of a primary and/or delayed supporting stump with simultaneous reconstructive procedures on the orbital bone structures.
 MATERIALS AND METHODS: A retrospective analysis of patients with subatrophy and anophthalmos with deformities of the orbital walls was carried out. Results were analyzed according to the criteria for the severity of clinical signs enophthalmos, deepening of the superior orbitopalpebral sulcus, prosthesis mobility.
 RESULTS: 22 patients with orbital bone deformities were operated and examined; they underwent surgery on the orbital walls in combination with evisceration with posterior scleral pole resection, neurectomy and implantation of a spherical endoprosthesis (in modifications) in 12 patients and delayed stump plasty in 10 patients with anophthalmos. It was possible to eliminate enophthalmos in 18 patients, to correct the retraction of the upper eyelid on the prosthesis side in 19 patients, and to significantly increase the mobility of the prosthesis in 9 patients.
 CONCLUSIONS: Carrying out a combined surgical procedure aimed at restoring a voluminous mobile primary or delayed supporting stump and eliminating the deformation of the orbital walls with restoring the lost volume creates conditions for optimal individual ocular prosthetics, significantly reduces prosthesis enophthalmos, increases its mobility and improves cosmetic results of rehabilitation.

Human-prosthesis cooperation: combining adaptive prosthesis control with visual feedback guided gait

BackgroundPersonalizing prosthesis control is often structured as human-in-the-loop optimization. However, gait performance is influenced by both human control and intelligent prosthesis control. Hence, we need to consider both human and prosthesis control, and their cooperation, to achieve desired gait patterns. In this study, we developed a novel paradigm that engages human gait control via user-fed visual feedback (FB) of stance time to cooperate with automatic prosthesis control tuning. Three initial questions were studied: (1) does user control of gait timing (via visual FB) help the prosthesis tuning algorithm to converge faster? (2) in turn, does the prosthesis control influence the user’s ability to reach and maintain the target stance time defined by the feedback? and (3) does the prosthesis control parameters tuned with extended stance time on prosthesis side allow the user to maintain this potentially beneficial behavior even after feedback is removed (short- and long-term retention)?MethodsA reinforcement learning algorithm was used to achieve prosthesis control to meet normative knee kinematics in walking. A visual FB system cued the user to control prosthesis-side stance time to facilitate the prosthesis tuning goal. Seven individuals without amputation (AB) and four individuals with transfemoral amputation (TFA) walked with a powered knee prosthesis on a treadmill. Participants completed prosthesis auto-tuning with three visual feedback conditions: no FB, self-selected stance time FB (SS FB), and increased stance time FB (Inc FB). The retention of FB effects was studied by comparing the gait performance across three different prosthesis controls, tuned with different visual FB.Results(1) Human control of gait timing reduced the tuning duration in individuals without amputation, but not for individuals with TFA. (2) The change of prosthesis control did not influence users’ ability to reach and maintain the visual FB goal. (3) All participants increased their prosthesis-side stance time with the feedback and maintain it right after feedback was removed. However, in the post-test, the prosthesis control parameters tuned with visual FB only supported a few participants with longer stance time and better stance time symmetry.ConclusionsThe study provides novel insights on human-prosthesis interaction when cooperating in walking, which may guide the future successful adoption of this paradigm in prosthesis control personalization or human-in-the-loop optimization to improve the prosthesis user’s gait performance.

Biomechanical Impacts of Toe Joint With Transfemoral Amputee Using a Powered Knee-Ankle Prosthesis.

Transfemoral amputees are currently forced to utilize energetically passive prostheses that provide little to no propulsive work. Among the several joints and muscles required for healthy walking, the ones most vital for push-off assistance include the knee, ankle, and metatarsophalangeal (MTP) joints. There are only a handful of powered knee-ankle prostheses (also called powered transfemoral prostheses) in literature and few of them comprise a toe-joint. However, no one has researched the impact of toe-joint stiffness on walking with a power transfemoral prosthesis. This study is aimed at filling this gap in knowledge. We conducted a study with an amputee and a powered transfemoral prosthesis consisting of a spring loaded toe-joint. The prosthesis's toe-joint stiffness was varied between three values: 0.83 Nm/deg, 1.25 Nm/deg, and infinite (rigid). This study found that 0.83 Nm/deg stiffness reduced push-off assistance and resulted in compensatory movements that could lead to issues over time. While the joint angles and moments did not considerably vary across 1.25 Nm/deg and rigid stiffness, the latter led to greater power generation on the prosthesis side. However, the 1.25 Nm/deg joint stiffness resulted in the least power production from the intact side. We, thus, concluded that the use of a stiff toe-joint with a powered transfemoral prosthesis can reduce the cost of transport of the intact limb.

A comparative evaluation of bite pressure between single implant prosthesis and natural teeth: An in-vivo study

Aim of the Study: To evaluate and compare bite pressure among individuals with implant prosthesis on one side and natural dentition on the contralateral side in the mandibular first molar region using the Nupai bite scan system.Materials and Methods: A total of 30 individuals (15 in which implant prosthesis on the right side and 15 in which implant prosthesis on the left side) with implant prosthesis on one side and natural dentition on the contralateral side participated in the study. The bite pressure was measured at the first molar area on both sides using Nupai bite scan.Results: Maximum bite pressure, average bite pressure, and the amount of the pressed area were found to be more on the natural dentition side in comparison to the side with implant prosthesis. The average pressure on natural teeth was 25.33 MPa and on implant prosthesis, 21.27 MPa.Conclusion: The present study concludes that the measured bite pressure at the natural dentition side is found to be higher than those at the fabricated implant prosthesis side. P value for average bite pressure is 0.033, which is significant (P < 0.05).

CT evaluation for sarcopenia involving the psoas and paravertebral muscles in patients with total hip arthroplasty.

Computed tomography (CT) has been validated in diagnosing sarcopenia in various clinical conditions. To evaluate the core abdominal muscles in terms of sarcopenia in patients with total hip arthroplasty (THA) with and without complication. Retrospective analysis of patients with a pelvic CT revealed 145 consecutive patients with THA. Also, 118 consecutive cases with normal CT scans constituted the control group. The area and density measurements of bilateral psoas (PSA, psoas area; PSD, psoas density) and paravertebral (PVA, paravertebral area; PVD, paravertebral density) muscles were performed at the level of L3 or L4 vertebrae regardless of prosthesis side. All measurements were evaluated in normal cases and in patients with THA, as well as in patients with complicated prostheses. In the whole population and subgroup of patients with bilateral THA, bilateral PSA, PSD, and PVD but not the PVA were lower in patients with THA compared to controls (all p < 0.01). In patients with unilateral prostheses, ipsilateral PSA, PSD, and bilateral PVD but not the PVA were lower compared to controls (all p < 0.01). Furthermore, in patients with unilateral prostheses with complication, only ipsilateral PSD was lower compared to patients with unilateral prostheses without complication (all p < 0.05) and in patients with bilateral prostheses with complication, bilateral PSA, PSD, and PVD but not the PVA were lower compared to patients with bilateral prostheses without complication (all p < 0.05). Sarcopenia indicated by the area and density measurements of core abdominal muscles can be associated with the presence and complication of hip prostheses.

Stand-Up, Squat, Lunge, and Walk With a Robotic Knee and Ankle Prosthesis Under Shared Neural Control.

Emerging robotic knee and ankle prostheses present an opportunity to restore the biomechanical function of missing biological legs, which is not possible with conventional passive prostheses. However, challenges in coordinating the robotic prosthesis movements with the user's neuromuscular system and transitioning between activities limit the real-world viability of these devices. Here we show that a shared neural control approach combining neural signals from the user's residual limb with robot control improves functional mobility in individuals with above-knee amputation. The proposed shared neural controller enables subjects to stand up and sit down under a variety of conditions, squat, lunge, walk, and seamlessly transition between activities without explicit classification of the intended movement. No other available technology can enable individuals with above-knee amputations to achieve this level of mobility. Further, we show that compared to using a conventional passive prosthesis, the proposed shared neural controller significantly reduced muscle effort in both the intact limb (21–51% decrease) and the residual limb (38–48% decrease). We also found that the body weight lifted by the prosthesis side increased significantly while standing up with the robotic leg prosthesis (49%–68% increase), leading to better loading symmetry (43–46% of body weight on the prosthesis side). By decreasing muscle effort and improving symmetry, the proposed shared neural controller has the potential to improve amputee mobility and decrease the risk of falls compared to using conventional passive prostheses.

Open Proximal Contact with Implant-Supported Fixed Prostheses Compared with Tooth-Supported Fixed Prostheses: A Systematic Review and Meta-analysis.

To investigate the odds of developing open proximal contact (OPC) between implant-supported fixed prostheses and adjacent teeth compared with that between tooth-supported fixed prostheses and adjacent teeth. A search was conducted in the Ovid MEDLINE, Embase, and Web of Science databases for clinical studies on OPC developed with implant-supported prostheses or tooth-supported prostheses. A meta-analysis was performed using statistical software to estimate the odds of developing OPC with implant-supported prostheses compared with tooth-supported prostheses, with a 95% confidence interval (CI). The statistical significance was defined as P < .05. The odds ratio (OR) of developing OPC with implant-supported prostheses was 2.46 compared with tooth-supported prostheses (95% CI [1.21 to 5.01]; P = .013]. However, the data were highly heterogenous (τ2 = 0.40, I2 = 95.67%). The total estimates of developing OPC were 41% (95% CI [30% to 54%]) with implant-supported prostheses and 22% (95% CI [18% to 26%]) with tooth-supported prostheses. OPC was more prevalent at the mesial side than at the distal side of implant-supported prostheses (OR = 2.38, 95% CI [0.94 to 6]; P = .066), whereas OPC was more prevalent at the distal side than at the mesial side of tooth-supported prostheses (OR = 1.94, 95% CI [1.09 to 3.45]; P = .024). There was no statistically significant difference in developing OPC with covariates of sex, age, arch, splinting of implants or adjacent teeth, region, and vitality of adjacent teeth, retention type, opposing dentition, occlusal force, parafunctional activities, and follow-up time. OPC was found to increase 9% per year with implant-supported prostheses (OR = 1.09). The estimate of interproximal gap next to implant-supported prostheses was 245.8 μm (95% CI [86.4 to 405.3 μm]). Within the limitations of this systematic review and meta-analysis, the odds of developing OPC were significantly higher with implant-supported prostheses than with tooth-supported prostheses. However, the data were highly heterogenous, and thus, a well-designed randomized clinical study needs to be conducted to validate the results of this systematic review.

Effects of extended stance time on a powered knee prosthesis and gait symmetry on the lateral control of balance during walking in individuals with unilateral amputation

BackgroundIndividuals with lower limb amputation commonly exhibit large gait asymmetries that are associated with secondary health issues. It has been shown that they are capable of attaining improved temporal and propulsive symmetry when walking with a powered knee prosthesis and visual feedback, but they perceive this pattern of gait to be more difficult. Rather than improving the efficiency of gait, improved gait symmetry may be increasing individuals’ effort associated with maintaining lateral balance.MethodsIn this study, we used a simple visual feedback paradigm to increase the prosthesis-side stance time of six individuals with unilateral TFA or KD as they walked on a powered knee prosthesis at their self-selected speed. As they walked more symmetrically, we evaluated changes in medial-lateral center-of-mass excursion, lateral margin of stability, stride width, and hip abductor activity.ResultsAs the subjects increased their prosthesis-side stance time, their center-of-mass excursion and hip abductor activity significantly increased, while their lateral margin of stability significantly decreased on the prosthesis-side only. Stride width remained relatively unchanged with testing condition.ConclusionsExtended stance time on a powered knee prosthesis (yielding more symmetric gait) challenged the lateral balance of individuals with lower limb amputation. Lateral stability may be a reason they prefer an asymmetric gait, even with more advanced technology. Hip muscular changes post-amputation may contribute to the decline in stability on the prosthesis side. Interventions and advancements in prosthesis control aimed at improving their control of lateral balance may ameliorate the difficulty in walking with improved gait symmetry.

Orthopaedic metallic artefact reduction algorithm facilitates CT evaluation of the urinary tract after hip prosthesis

To examine the improvement in the visualisation of bladder and ureteric pathologies next to a hip prosthesis with metallic artefact reduction for orthopaedic implants (O-MAR). Thirty-four patients who underwent pelvic computed tomography (CT) for non-prosthesis-related causes were enrolled retrospectively. Portal venous phase scans were reconstructed both with standard iterative reconstruction (ITR) and with O-MAR. The density of the ureters and the bladder was measured at both sides in the plane of the prosthesis. A semi-quantitative score was also used to assess visibility. The R (version 3.4.1) package was used for statistical analysis. The average (μ) density of the 41 prosthesis side ureters was significantly lower on ITR images (μ=-94.76±150.48 [±SD] HU) than on O-MAR images (μ=-13.40±36.37 HU; p<0.0004). The difference between the ITR and O-MAR (μ=-138.62±182.64 versus -35.55±40.21 HU; p<0.0003) was also significant at the prosthesis side of the bladder. The visibility of the prosthesis side ureters was improved: 53.7% was obscured on ITR series compared to 4.9% on O-MAR. The visibility score was also better across all levels (p<0.001) with O-MAR. In four cases (13%), the O-MAR images significantly changed the diagnosis: in two cases ureteric stones, in one case each a bladder stone and a bladder tumour were discovered. O-MAR reconstruction of CT images significantly improves the visibility of the urinary tract adjacent to metallic hip implants. Thus, O-MAR is essential for detecting ureteric and bladder pathologies in patients with a hip prosthesis.

Development of a Mechanistic Hypothesis Linking Compensatory Biomechanics and Stepping Asymmetry during Gait of Transfemoral Amputees.

Objective Gait asymmetry is a common adaptation observed in lower-extremity amputees, but the underlying mechanisms that explain this gait behavior remain unclear for amputees that use above-knee prostheses. Our objective was to develop a working hypothesis to explain chronic stepping asymmetry in otherwise healthy amputees that use above-knee prostheses. Methods Two amputees (both through-knee; one with microprocessor knee, one with hydraulic knee) and fourteen control subjects participated. 3D kinematics and kinetics were acquired at normal, fast, and slow walking speeds. Data were analyzed for the push-off and collision limbs during a double support phase. We examined gait parameters to identify the stepping asymmetry then examined the external work rate (centre of mass) and internal (joint) power profiles to formulate a working hypothesis to mechanistically explain the observed stepping asymmetry. Results Stepping asymmetry at all three gait speeds in amputees was characterized by increased stance phase duration of the intact limb versus relatively normal stance phase duration for the prosthesis limb. The prosthesis limb contributed very little to positive and negative work during the double support phase of gait. To compensate, the intact leg at heel strike first provided aid to the deficient prosthetic ankle/foot during its push-off by doing positive work with the intact knee, which caused a delayed stance phase pattern. The resulting delay in toe-off of the intact limb then facilitated the energy transfer from the more robust intact push-off limb to the weaker colliding prosthesis side. This strategy was observed for both amputees. Conclusions There is a sound scientific rationale for a mechanistic hypothesis that stepping asymmetry in amputee participants is a result of a motor adaptation that is both facilitating the lower-leg trajectory enforced by the prosthesis while compensating for the lack of work done by the prosthesis, the cost of which is increased energy expenditure of the intact knee and both hips.

VD07 CAN A BENTALL PROCEDURE GET COMPLICATED?

We present a case of a 61 years-old man with aortic dissection involving the arch and descending aorta 7 years after a Bentall and CABG procedure reoperated 3 years later for right button pseudoaneurysm. In this video we show our surgical approach. CPB was established using direct brachiocephalic trunk and right atrial cannulation. A moderate hypotermic circulatory arrest (26°C) was utilized and once the aortic arch was opened, cerebral perfusion was achieved separately for the brachiocephalic trunk and for the left carotid and subclavian arteries. A FET procedure was carried out using a 26/28 mm Thoraflex prosthesis. Distal reperfusion was resumed through the prosthesis side branch after distal anastomosis was completed. Left subclavian and left carotid arteries were reimplanted during rewarming. Once proximal anastomosis was completed, heart was restarted and brachiocefalic trunk reattached on a beating heart.

Retrospective 2- to 7-Year Follow-Up Study of 20 Double Full-Arch Implant-Supported Monolithic Zirconia Fixed Prostheses: Measurements and Recommendations for Optimal Design.

To measure the extension of cantilever lengths, thicknesses, and heights of zirconia prostheses in the lingual and facial areas of the distal screw access openings, and to evaluate the clinical performance regarding chipping or fracture of the distal cantilevered sections of double full-arch CAD/CAM screw-retained, stained, monolithic zirconia, gingival-colored ceramic implant-supported fixed prostheses (MZ-FPs). Ten edentulous patients were provided with a total of 20 CAD/CAM double full-arch MZ-FPs. The zirconia thicknesses around distal screw access openings at three different levels (crown height space, screw access opening lengths, and dimensions of the cantilevered segments) were measured in the resin prototypes. Patients were evaluated clinically (visually) without magnification, with intraoral digital photography, and radiologically by the author, approximately every 6 months. Ten patients with 20 MZ-FPs were evaluated. Twenty resin prototypes with 35 cantilevered segments (15 maxillary, 20 mandibular) were measured. The lingual and facial thicknesses of the resin frameworks and the crown height spaces of 35 distal access openings were measured. The average extension of the maxillary cantilever segments was 7.72 mm; the mandibular cantilever average was 13.72 mm. The average crown height space for maxillary prostheses was 13.27 mm, for the mandibular prostheses it was 11.89 mm. Zirconia thickness around distal screw access openings at the middle of the crowns, margins and middle of the gingival areas (buccal side of maxillary prostheses) was 4.29, 3.79, and 3.87 mm, respectively. On the lingual sides the thicknesses were 3.13, 2.85, and 3.15 mm, respectively. For mandibular prostheses the thicknesses were 3.56, 3.08, and 3.15 mm, respectively, on the buccal sides, and 2.07, 2.00, and 2.99 mm, respectively, on the lingual sides. No implant failure or changes in the occlusal surface, chipping of the cuspid or incisal edges, or prosthesis distal extension fractures were observed during follow-up periods ranging from 2 to 7 years. The survival rate was 100% for implants and prostheses. In one of the patients, chipping of the pink ceramic was noted in the maxillary prosthesis 36 months after placement. The results of this study indicated that full-arch MZ-FPs without cutback, or with partial digital cutback and veneering ceramic, were a therapeutic option. Recommendations regarding the thickness of zirconia at the level of the distal screw access openings, the crown height spaces, and the lengths of the cantilever segments were recorded. Additional in vitro and clinical studies will be required for more scientific analysis of the criteria for design of this type of prosthesis to minimize prosthetic complications. Long-term and multicenter studies are needed to corroborate the findings discussed in this report.

The Effect of Radial Head Hemiarthroplasty Geometry on Proximal Radioulnar Joint Contact Mechanics

To compare the joint contact area and peak contact stress of different radial head (RH) hemiarthroplasty articular profiles for the proximal radioulnar joint (PRUJ) to the native radial head with the hypothesis that the side radius and side angle closest to the native mating ulnar articular profile would provide the best contact mechanics. Finite element models generated from the computed tomography geometry of 14 native elbows (73 ± 17.5 years) were subjected to 12 different RH profiles having varying side radii (flat [r= ∞ mm], 16.25, 8.12, and 4.50 mm) and side angles (0°, 5°, and 10°) under a constant compressive 20-N medial load. Contact areas and peak contact stresses were computed and compared with the native joint. On average, RH implants significantly reduced PRUJ contact area by 55% ± 16% and increased peak contact stress by 337% ± 241% compared with the native RH. The prosthesis side radius had significant effects on both contact area and stress, but side angle did not. The 16.25-mm radii produced the largest contact areas, and the 4.50-mm radius model generated the smallest contact areas. As the side radius was decreased, peak contact stress was reduced as the contact migrated toward the center of the native ulnar articulation, although the 8.12-mm radius achieved the lowest peak contact stress. Whereas RH hemiarthroplasty side radius can affect both contact area and peak contact stress, the magnitude of the effect on contact area is relatively small compared with that of the peak contact stress. Furthermore, although a flat RH side profile with a side angle of 5° more closely matched the side profile of the native ulnas used in the present study, the optimal profile was found to be a smaller radius of 8.12 mm. Optimizing PRUJ contact mechanics after metallic RH hemiarthroplasty may contribute to better clinical outcomes by reducing the potential for native cartilage degeneration.

The relationship between trans-femoral prosthesis alignment and the center trajectory of plantar pressure in the frontal plane.

[Purpose] It is difficult to identify by visual observation whether alignment abnormalities in trans-femoral prostheses in the frontal plane are attributable to the adduction angle or the abnormal alignment of the positions of the medial and lateral sides of the socket in relation to the foot. Therefore, we focused on the trajectory of the center of plantar pressure during walking, and we proposed a method for differentiating these two alignment abnormalities. [Subjects and Methods] We recruited 4 trans-femoral unilateral amputees. Bench alignment was achieved initially. We compared the amplitude of the trajectory of the center of plantar pressure when walking under 2 conditions: 1) when changing the adduction angle and 2) when changing the positional relationship between the socket and the foot. [Results] It was not possible to distinguish between the 2 types of malalignment on the prosthesis side. There was a significant difference when changing the positional relationship on the contralateral side. Thereby, the plantar pressure of the contralateral side could be used to distinguish between the 2 types of malalignment. [Conclusion] The results of this study suggested that trans-femoral prosthesis malalignment could be evaluated through the plantar pressure of the contralateral side in amputees.

Transfemoral amputee recovery strategies following trips to their sound and prosthesis sides throughout swing phase.

BackgroundRecovering from trips is challenging for transfemoral amputees, and attempts often result in falls. Better understanding of the effects of the sensory-motor deficits brought by amputation and the functional limitations of prosthetic devices could help guide therapy and fall prevention mechanisms in prostheses. However, how transfemoral amputees attempt to recover from trips on the sound and prosthesis sides throughout swing phase is poorly understood.MethodsWe tripped eight able-bodied subjects and eight unilateral transfemoral amputees wearing their prescribed prostheses. The protocol consisted of six repetitions of 6 and 4 points throughout swing phase, respectively. We compared recovery strategies in able-bodied, sound side and prosthesis side limbs. The number of kinematic recovery strategies used, when they were used throughout swing phase, and kinematic characteristics (tripped limb joint angles, bilateral trochanter height and time from foot arrest to foot strike) of each strategy were compared across limb groups. Non-parametric statistical tests with corrections for post-hoc tests were used.ResultsAmputees used the same recovery strategies as able-bodied subjects on both sound and prosthesis sides, although not all subjects used all strategies. Compared to able-bodied subjects, amputees used delayed-lowering strategies less often from 30-60 % of swing phase on the sound side, and from 45-60 % of swing phase on the prosthesis side. Within-strategy kinematic differences occurred across limbs; however, these differences were not consistent across all strategies. Amputee-specific recovery strategies—that are not used by control subjects—occurred following trips on both the sound and prosthesis sides in mid- to late swing.ConclusionsCollectively, these results suggest that sensory input from the distal tripped leg is not necessary to trigger able-bodied trip recovery strategies. In addition, the differences between sound and prosthesis side recoveries indicate that the ability of the support leg might be more critical than that of the tripped leg when determining the response to a trip. The outcomes of this study have implications for prosthesis control, suggesting that providing correct and intuitive real-time selection of typical able-bodied recovery strategies by a prosthetic device when it is the tripped and the support limb could better enable balance recovery and avoid falls.Electronic supplementary materialThe online version of this article (doi:10.1186/s12984-015-0067-8) contains supplementary material, which is available to authorized users.

Electrospun nanofiber scaffolds and plasma polymerization: a promising combination towards complete, stable endothelial lining for vascular grafts.

In the quest to reduce risk of thrombosis in vascular grafts, it is essential to provide a surface with morphological and mechanical properties close to those of the extracellular matrix beneath the luminal endothelium, and to favor the growth of a confluent, stable monolayer of endothelial cells. This is accomplished here by combining electrospun poly(ethylene terephthalate) (PET) mats with an amine-rich thin plasma-polymerized coating, designated "L-PPE:N." Its deposition does not modify the open, highly porous mats and leads only to small changes in mechanical properties. L-PPE:N significantly improves the adhesion and growth of human umbilical vein endothelial cells (HUVEC) and their resistance to flow-induced shear stress. These properties favor the formation of desired confluent HUVEC monolayers on the topmost surface, unlike conventional vascular grafts (ePTFE or woven PET), where cells migrate inside the material. This combination is therefore highly advantageous for the pre-endothelialization of the luminal side of small-diameter vascular prostheses.

Maximum bite force following unilateral implant‐supported prosthetic treatment: within‐subject comparison to opposite dentate side

Bite force is a significant component of chewing and masticatory function. The literature lacks studies that compare bite force values of implant-supported fixed bridges to natural dentition within same subjects. The objective of the study was to assess maximum occlusal bite force (MBF) among patients with an implant-supported fixed prosthesis and compare it to their opposite dentate side and also to determine the effect of gender, age and Body Mass Index (BMI) on maximum occlusal bite force. Forty patients (20 males and 20 females, mean age = 42.7 ± 9.6 years) with an implant-supported fixed prosthetic rehabilitation on one side and dentate on the other side were recruited into this study. Participants' MBF were measured bilaterally at the first molar region using a digital hydraulic occlusal force gauge (GM10). The measurements were repeated three times (with 45 s intervals between times) for each side, and the highest value of the bite force (MBF) was recorded for each side. The mean MBF was 577.9 N at the implant-supported prosthesis side and 595.1 N at the dentate side. The average MBF was higher at the dentulous side (P < 0.05). Maximum occlusal bite force was higher in males and participants with higher weight and height. However, BMI was not significantly related to MBF values. Maximum occlusal bite force values at the dentate side were slightly (3%) but significantly higher than MBF at implant-supported prosthesis side. Males, taller patients and patients with higher weights had higher MBF values. Body mass index was not significantly related to MBF values.

Evaluation of gait performance of a hemipelvectomy amputation walking with a canadian prosthesis.

Background. Hemipelvectomy amputation is a surgical procedure in which lower limb and a portion of pelvic are removed. There are a few studies in the literature regarding the performance of subjects with hip disarticulation during walking. However, there is no study on gait analysis of hemipelvectomy subject. Therefore, the aim of this paper was to evaluate the gait and stability of subject with hemipelvectomy amputation. Case Description and Methods. A subject with hemipelvectomy amputation at right side was involved in this study. He used a Canadian prosthesis with single axis ankle joint, 3R21 knee joint, and 7E7 hip joint for more than 10 years. The kinetic and kinematic parameters were collected by a motion analysis system and a Kistler force platform. Findings and Outcomes. There was a significant difference between knee, hip, and ankle range of motions and their moments in the sound and prosthesis sides. In the other side, the stability of the subject in the anteroposterior direction seems to be better than that in the mediolateral direction. Conclusions. There was a significant asymmetry between the kinetic and kinematic performance of the sound and prosthesis sides, which may be due to lack of muscular power and alignment of prosthesis components.