Prospects For Development Research Articles

Statistical Analyses of the Attitude of Interested Parties to Marketing Strategies of Azerbaijan Universities

Purpose: The purpose of this study , which examines the quality of educational services and the attitude of interested parties to the marketing strategies applied to increase this quality, is to determine the satisfaction provided by the quality of educational services defined by revealing the expectations of stakeholders in the position of customers from these educational services during the application of the marketing strategy related to educational services. When studying in the context of the quality of education in Azerbaijan, the main purpose of the study is to study the attitude of stakeholders to the marketing strategies applied in the education sector of our country. Method: Our study is made up of people who are over 16 years old and are studying in Azerbaijan's higher education institutions. The questionnaire method used for data collection will be effective in obtaining direct information from the respondents. The survey process was carried out in a visual form. 409 people participated in the survey. Most of the respondents are between 16-40 years old. In order to avoid any loss of information, it was mandatory to answer all the questions that will be used in the analysis, and for this reason, the mentioned 213 respondents answered all the main necessary survey questions. The data collection process took place from January 8, 2024 to January 28, 2024. The survey consists of 56 questions and is divided into 2 parts: demographic questions and statistical questions. Quantities corresponding to the questions were calculated in SPSS. Results and Discussion: By evaluating the results and impact of marketing strategies in the field of education in Azerbaijan, it can help to create prospects for development in the field of education and cooperation of interested partners in the region. Also, the main goal is to develop and analyze marketing strategies in the field of education in Azerbaijan and to clarify the role and influence of stakeholders in this process. All this can contribute to the development of more effective educational marketing strategies and a better education system. Research Implications: The conducted research and the results obtained through the research have a number of both theoretical and practical significance. So, since the application of marketing strategies in education and the attitudes of interested parties to these strategies - students and consumers - are comprehensively investigated, the results of this research will be more optimal. In this sense, the research carried out was prepared considering the level of satisfaction of the students, the factors affecting the choice of the educational institution, and the quality variables in education as factors affecting the marketing strategies in education.

The Development of Yunnan “New Folk Songs”

Background and Aim: This study investigates the evolution of the “New Folk Song” in Yunnan and analyzes how historical, cultural, and social changes have influenced their development. Yunnan folk songs are a cultural product with local characteristics and close to the development of the working people in Yunnan that is close to the people's daily life. The "New Folk Songs" of Yunnan is a musical form combining “nation” and “modern” innovation. In the process of development, it is constantly endowed with new definitions and connotations and presents the situation of diversified development. Due to the special historical and social environment of Yunnan, a large number of “New Folk Songs” with rich themes and excellent quality have emerged in Yunnan during the period of the late Qing Dynasty and the early Republic of China, the Revolutionary War, the “Cultural Revolution”, and the era of peace and development in recent years. The results show that Yunnan's “New Folk Songs” evolved through the integration of modern and traditional elements, reflecting the unique social and cultural dynamics of Yunnan over the past hundred years. To study the development of “New Folk Songs” in Yunnan, this study is not only a record of musical life in different periods, but also the development trajectory of different musical works in Yunnan across the century, but also a study of the development history of music creation in Yunnan. Materials and Methods: This Article aimed to study related literature to find out the development of Yunnan's “New Folk Songs”. The instrument for collecting data was documentary research. Relevant journals, academic papers, books, magazines, and online information related to the development of Yunnan's “New Folk Songs” are reviewed and organized. From the perspective of creation and music ontology, the style characteristics and creation characteristics of Yunnan "new folk songs" in different periods are analyzed, to explore the development of Yunnan “New Folk Songs” in Yunnan. Results: Throughout the development of “New Folk Songs” in Yunnan, its creation characteristics are contemporary, national, and regional; music works have the style characteristics of Yunnan minority elements. This paper will analyze and study the above characteristics in depth. This study is beneficial to improve the reader's understanding of Yunnan's “New Folk Songs” and understanding, through the development of “New Folk Songs” in Yunnan, to explore the development prospect of “New Folk Songs”, Yunnan for music workers can provide certain reference and reference, also for the Yunnan “New Folk Songs” and singing practice, teaching practice provides reference way, also further promote Yunnan traditional folk song inheritance and the sustainable development of “New Folk Songs”. At the same time, through this study, it is hoped to help the exploration of Yunnan's “New Folk Songs” style, and also to promote the inheritance of the existing Yunnan traditional folk music culture and establish awareness of the exploration and protection of Yunnan local music materials. Conclusion: The development of “New Folk Songs” in Yunnan is reflected in the creative characteristics and style characteristics changing with the changes of the times. The social environment, economic situation, and policy system of a country in an era will often affect the artistic creation of the creators with subjective or objective factors. Therefore, In this paper, the horizontal melody and vertical harmonic layout of music works in the budding period of Yunnan “New Folk Songs” (The Late Qing Dynasty and The Early Republic of China), The War Period (1931-1949), The 17th years of the Founding of the People's Republic of China (1949-1966), The Ten Years of the “Cultural Revolution” (1966-1976), and The Innovation and Development period (1978-2020), Relying on the musical activities in various historical periods, Analyzing the common and personalized creation characteristics of creators and the formation process of Yunnan local ethnic creation concept. Thus, the different purposes of creation, the different contents of the times, the different style characteristics, the different forms of expression, and then to understand the development of “New Folk Songs” in Yunnan.

In-Depth Examination of the Functionality and Performance of the Internet Hospital Information Platform: Development and Usability Study.

Internet hospitals (IHs) have rapidly developed as a promising strategy to address supply-demand imbalances in China's medical industry, with their capabilities directly dependent on information platform functionality. Furthermore, a novel theory of "Trinity" smart hospital has provided advanced guidelines on IH constructions. This study aimed to explore the construction experience, construction models, and development prospects based on operational data from IHs. Based on existing information systems and internet service functionalities, our hospital has built a "Smart Hospital Internet Information Platform (SHIIP)" for IH operations, actively to expand online services, digitalize traditional health care, and explore health care services modes throughout the entire process and lifecycle. This article encompasses the platform architecture design, technological applications, patient service content and processes, health care professional support features, administrative management tools, and associated operational data. Our platform has presented a set of data, including 82,279,669 visits, 420,120 online medical consultations, 124,422 electronic prescriptions, 92,285 medication deliveries, 6,965,566 prediagnosis triages, 4,995,824 offline outpatient appointments, 2025 medical education articles with a total of 15,148,310 views, and so on. These data demonstrate the significant role of IH as an indispensable component of our physical hospital services, with deep integration between online and offline health care systems. The upward trends in various data metrics indicate that our IH has gained significant recognition and usage among both the public and healthcare workers, and may have promising development prospects. Additionally, the platform construction approach, which prioritizes comprehensive service digitization and the 'Trinity' of the public, healthcare workers, and managers, serves as an effective means of promoting the development of Internet Hospitals. Such insights may prove invaluable in guiding the development of IH and facilitating the continued evolution of the Internet healthcare sector.

Review and prospect on Metal-organic framework-based Separators for Lithium–Sulfur Battery

With the continuous advancement of technology, wearable smart devices and electric vehicles (EVs) have become an integral part of our daily lives. The increasing demand for energy from these devices and vehicles has driven the pursuit of high-performance rechargeable battery technology. In particular, the widespread adoption of electric vehicles has set higher standards for the energy density and cycle life of batteries. However, the energy density of the widely used lithium-ion batteries is currently limited by the theoretical capacity of commercial cathode materials, and there are certain challenges in terms of safety and cost-effectiveness. Therefore, the development of a new generation of rechargeable batteries with higher energy density, better safety, and more economical cost is particularly urgent. Lithium-sulfur batteries, due to their high energy density, high economic benefits, and high environmental friendliness, are considered to be one of the most promising successors to the widely used lithium-ion batteries. However, in practical applications, the electrochemical performance of lithium-sulfur batteries still needs to be improved. In particular, the poor conductivity of sulfur/lithium and the shuttle effect of polysulfides make the cycle life of the battery less than ideal, and lithium-sulfur batteries (LSB) are still far from achieving large-scale commercialization. The separator used in lithium-sulfur batteries plays a crucial role in its cycle performance and safety. The current commercial separator lacks the ability to effectively regulate the shuttle of polysulfides and is prone to thermal runaway at high temperatures. Therefore, to improve these issues, various functional materials have been used to modify the separator. Among them, as a new type of porous coordination polymer, metal organic frameworks (MOFs) have become a promising material for modifying separators due to their large specific surface area and highly ordered tunable nano-holes.At the same time, their rich inorganic nodes and designable organic ligands allow for the customization of pore chemistry at the molecular level, which can interact with the electroactive components in lithium-sulfur batteries in a tunable manner. This article reviews the reaction mechanism of lithium-sulfur batteries and the structural advantages of MOFs in terms of pore chemistry and morphology and briefly introduces the research progress of MOF-based interfacial layers for the functionalization of LSB separators in recent years. It elaborates on the mechanisms by which various modified separators improve electrochemical performance and provides a prospect for the development prospects of the field.

Classical Medical Cases of Doubt Narrative Foreclosure in Traditional Chinese Medicine and Their Corresponding Narrative Mediation

Abstract: Narrative foreclosure is a phenomenon highlighted within the Chinese narrative medicine system, characterized by a state in which individuals become overly suspicious due to certain events in their development, leading to profound concerns about their health and safety. This article employs the logical discourse framework of Chinese narrative medicine to illustrate the experiences of various patients exhibiting typical instances of narrative foreclosure in traditional Chinese medicine (TCM) cases, such as Bei Gong She Ying (杯弓蛇影 snake shadow in the cup), Wu Qiu Zhi Chong (吴球治虫Wu Qiu treats worms), and Fa Jing Qu She (法靖驱蛇 Fajing drives away snakes). It explores how TCM practitioners leverage narrative wisdom to facilitate patients in dispelling their internal doubts through the concept of Bu Yao Wei Yao (不药为药 healing diseases without medicine). Through these medical cases, the article advocates for the significance of narrative competencies among medical practitioners in diagnosing and treating patients, alongside the use of pharmaceuticals and surgical interventions. Additionally, it outlines the prospects for the future development of narrative approaches in TCM.

Current Status and Future Prospects of Intellectual Property Finance Development

Current Status and Future Prospects of Intellectual Property Finance Development

Research Progress on Solid-State Electrolytes in Solid-State Lithium Batteries: Classification, Ionic Conductive Mechanism, Interfacial Challenges

Solid-state lithium batteries exhibit high-energy density and exceptional safety performance, thereby enabling an extended driving range for electric vehicles in the future. Solid-state electrolytes (SSEs) are the key materials in solid-state batteries that guarantee the safety performance of the battery. This review assesses the research progress on solid-state electrolytes, including polymers, inorganic compounds (oxides, sulfides, halides), and organic–inorganic composites, the challenges related to solid-state batteries in terms of their interfaces, and the status of industrialization research on solid-state electrolytes. For each kind of solid-state electrolytes, details on the preparation, properties, composition, ionic conductivity, ionic migration mechanism, and structure–activity relationship, are collected. For the challenges faced by solid-state batteries, the high interfacial resistance, the side reactions between solid-state electrolytes and electrodes, and interface instability, are mainly discussed. The current industrialization research status of various solid electrolytes is analyzed in regard to relevant enterprises from different countries. Finally, the potential development directions and prospects of high-energy density solid-state batteries are discussed. This review provides a comprehensive reference for SSE researchers and paves the way for innovative advancements in regard to solid-state lithium batteries.

Deep Lead Optimization: Leveraging Generative AI for Structural Modification.

The integration of deep learning-based molecular generation models into drug discovery has garnered significant attention for its potential to expedite the development process. Central to this is lead optimization, a critical phase where existing molecules are refined into viable drug candidates. As various methods for deep lead optimization continue to emerge, it is essential to classify these approaches more clearly. We categorize lead optimization methods into two main types: goal-directed and structure-directed. Our focus is on structure-directed optimization, which, while highly relevant to practical applications, is less explored compared to goal-directed methods. Through a systematic review of conventional computational approaches, we identify four tasks specific to structure-directed optimization: fragment replacement, linker design, scaffold hopping, and side-chain decoration. We discuss the motivations, training data construction, and current developments for each of these tasks. Additionally, we use classical optimization taxonomy to classify both goal-directed and structure-directed methods, highlighting their challenges and future development prospects. Finally, we propose a reference protocol for experimental chemists to effectively utilize Generative AI (GenAI)-based tools in structural modification tasks, bridging the gap between methodological advancements and practical applications.

Isolation, Characterization, and Optimization of Culture Medium for Local Straw-Degrading Bacteria from Northeastern Black Soils of China

In order to solve the problem of low and poor straw degradation in typical black soil areas of Northeast China, the present study was carried out to screen the potential of in situ strains with cellulose degradation ability from black soils of Northeast China to play a role in the resourceful utilization of straw and the development of sustainable agriculture. The straw degradation potential of the strains was evaluated by combining sodium carboxymethyl cellulose plate screening and cellulase viability assay; the species identification of the strains was carried out by morphology, physiology, biochemistry, and molecular biology; and the basic medium formulation of the strains was optimized by Box–Behnken response surface methodology. Ten cellulose-degrading strains were identified: ZL-5, ZL-69, ZL-88, ZL-95, ZL-111, ZL-137, ZL-139, ZL-140, ZL-187, and ZL-216, of which ZL-139 had the highest cellulase production capacity, with a cellulase secretion of 7.8781 U/mL in the enzyme-producing medium. ZL-139 was identified as Bacillus cereus; the optimized best formulation was glucose—4.284 g/L, yeast extract—1.454 g/L, MgSO4—0.417 g/L, KH2PO4—0.5 g/L, KH2PO4—0.5 g/L, K2HPO4—1.5 g/L, and NaCl—1.0 g/L. In conclusion, strain ZL-139 has good potential for crop straw degradation and can be a candidate strain for a straw-rotting agent in northeast China, with promising prospects for development and utilization.

Photodynamic therapy – modern views and innovations in dentistry

Photodynamic therapy (PDT) consists of three elements: a photosensitizer, light and oxygen. The photosensitizer has the property of selective accumulation in target tissues without harming healthy cells. This innovative therapeutic method has already been successfully adapted in many areas of medicine, such as dermatology, gynecology, urology and oncology. PDT is also beginning to be introduced in dentistry. The antibacterial and fungicidal properties of the photosensitizer are used to achieve better results in the medical and surgical treatment of patients. Objective. To analyze current scientifi data on the application of photodynamic therapy (PDT) in various fi of dentistry, evaluate its effectiveness, and assess prospects for development. Materials and methods. A review of recent scientifi literature was conducted, including original studies, systematic reviews, and meta-analyses focused on PDT application in dentistry. Data on mechanisms of action, clinical efficacy, and new developments in PDT were analyzed. Results. High effi of PDT was established in the treatment of periodontal diseases, peri-implantitis, endodontic infections, and oral oncological diseases. Advantages of combined application of PDT with other treatment methods were noted. Promising directions for PDT development were identifi including the creation of new photosensitizers and technological innovations in equipment. Conclusions. PDT is a promising treatment method in dentistry, demonstrating high efficacyand safety. Further research is aimed at optimizing treatment protocols, developing personalized approaches, and integrating PDT with other modern technologies.

Generation of hydrogen fuel on board vehicles with internal combustion engines

This article discusses advances in the design of hydrogen fuel engines; the main characteristics of the hybrid engine are studied; prospects for further research are outlined; development and improvement of engine designs, research of processes in engines running on natural gas and hydrogen. Transport is one of the key elements of modern civilization. Its condition and development prospects largely depend on the ability to supply transport power plants with fuel. The depletion of liquid hydrocarbon fuel reserves and problems of environmental pollution may present humanity with a choice - either to reduce transport transportation or to find new ways to supply energy to transport. OBJECTIVE: To review the electrochemical technologies used for the production of hydrogen at gas stations and the operation of hybrid electric vehicle engines using fuel cell batteries. Conduct a comparative analysis of the production and use of energy by electrochemical and traditional methods in vehicles. METHODS are based on analysis of literature data and mathematical calculations. For a passenger electric vehicle, the amount of electricity that can be obtained in a fuel cell by processing 1 kg of hydrogen was calculated. It has been shown that the specific fuel consumption for a hydrogen electric vehicle averages 1 kg of hydrogen per 100 km. Hydrogen has the potential to be the sustainable fuel of the future, reducing global dependence on fossil fuel resources and reducing carbon emissions from the transportation industry.

Tetrapanax papyriferus lignocellulosic skeleton aerogel enhanced with polyvinyl alcohol of high mechanical performance and thermal insulating

Biodegradable and renewable biomass aerogel has attracted significant attention because of its excellent characteristics. However, most aerogels were limited by poor mechanical strength and complex fabrication process. Herein, two delignified Tetrapanax papyriferus (TP) lignocellulosic samples (TP-SC, TP-FA/HAC) served as renewable porous skeletons with polyvinyl alcohol (PVA) modification to prepare high performance aerogels. The excellent pore structure facilitates the penetration of polyvinyl alcohol, which enhances the mechanical property and thermal stability of the resulting aerogel. The SC-8 h exhibited excellent mechanical strength with a bending stress of 102.9 MPa, 26.7 % increase in strain and 2.5 % in bending modulus compared to the TP-SC. The maximum thermal decomposition temperature of the FA/HAC-4 h was 358.6 °C, which was showed an outstanding thermal stability of the aerogel. Furthermore, these aerogels exhibited thermal insulating properties, and the maximum surface heating temperature after impregnation modification is lower than that of the original wood. This performance has a development prospect in the field of thermal insulation packaging and building structural materials. The high strength lignocellulosic skeleton aerogel could be prepared by a simple and effective strategy that preserved the original distinctive structure, offering a novel approach to the efficient utilization of TP.

Multi-Agent Approach to Political Discourse Translation: From Large Language Models to MAGIC-PTF System

This research addresses the automated translation of Chinese political discourse into Russian utilizing Large Language Model (LLM) optimization technologies and a multi-agent approach. The study focuses on developing the MAGIC-PTF system, which implements multi-stage text processing through the interaction of four specialized agents. The system's key component is the Style Agent, which ensures stylistic uniformity and terminological accuracy based on a specifically trained LLM. The Translator Agent performs the primary translation work and is responsible for the final text formatting. The Editor Agent conducts multi-level verification and correction of translations, considering linguistic, semantic, and cultural aspects. The Reader Agent analyzes the text from the target audience's perspective, evaluating its reception by native Russian speakers. The methodology integrates LLM optimization technologies and a multi-agent approach, with experimental testing conducted on the fourth volume of "Xi Jinping: The Governance of China" and its official Russian translation. The study includes a comprehensive analysis of system effectiveness using the COMET metric and comparative testing with existing machine translation platforms. The research's scientific novelty lies in developing a methodology for applying LLMs to specialized translation tasks and creating an effective coordination mechanism for intelligent agents in the translation process. Experimental research demonstrated MAGIC-PTF's superiority over traditional machine translation systems in key parameters: terminological accuracy, stylistic consistency, and preservation of culture-specific elements in political discourse. The developed system opens new possibilities for automated translation of political discourse and can be adapted for translating other specialized text types, confirming its significance for modern translation technology development. Of particular value is the system's scalability and adaptability to various language pairs and discourse types, creating prospects for further development in automated specialized text translation. The research findings also contribute to advancing the theory and practice of LLM application in professional translation.

From biomass to power: High-performance reactor design for coking-resistant operation

Biomass gasification coupled with solid oxide fuel cell (SOFC) technology utilizes the gas generated from biomass gasification directly as fuel for SOFC, thereby realizing power generation from solid waste. This technology combines the carbon–neutral feature of biomass with the high efficiency and low emissions of SOFC, making it a promising route for clean energy generation. However, biomass gasification syngas possesses a complex composition, including a high concentration of inert gases, which imposes higher requirements on SOFC. This study developed a multi-channel, hierarchical structural design based on the commercial NiO-yttria-stabilized zirconia (YSZ) material system, realizing high-performance power generation using biomass gasification syngas. The results showed that the combination of a unique structural design and an enhanced interface electrochemical reaction effectively mitigates the influence from inert composition dilution. When operating in gasification syngas with nearly 60 % inert components, the power density can reach 2.07 W·cm−2 (750 °C). In addition, due to the spatial separation of the inert support region and the electrochemically active region, the effect of controlling the position of carbon deposits was achieved, demonstrating 100 h stable operation with dry biomass gasification syngas. Hence, the combination of micro-tubular SOFC with distinctive structural regulation and biomass gasification exhibits promising prospects for further development.

Application of Nanoparticles in the Diagnosis and Treatment of Colorectal Cancer.

Colorectal cancer is a common malignant tumor with high morbidity and mortality rates, imposing a huge burden on both patients and the healthcare system. Traditional treatments such as surgery, chemotherapy and radiotherapy have limitations, so finding more effective diagnostic and therapeutic tools is critical to improving the survival and quality of life of colorectal cancer patients. While current tumor targeting research mainly focuses on exploring the function and mechanism of molecular targets and screening for excellent drug targets, it is crucial to test the efficacy and mechanism of tumor cell therapy that targets these molecular targets. Selecting the appropriate drug carrier is a key step in effectively targeting tumor cells. In recent years, nanoparticles have gained significant interest as gene carriers in the field of colorectal cancer diagnosis and treatment due to their low toxicity and high protective properties. Nanoparticles, synthesized from natural or polymeric materials, are NM-sized particles that offer advantages such as low toxicity, slow release, and protection of target genes during delivery. By modifying nanoparticles, they can be targeted towards specific cells for efficient and safe targeting of tumor cells. Numerous studies have demonstrated the safety, efficiency, and specificity of nanoparticles in targeting tumor cells, making them a promising gene carrier for experimental and clinical studies. This paper aims to review the current application of nanoparticles in colorectal cancer diagnosis and treatment to provide insights for targeted therapy for colorectal cancer while also highlighting future prospects for nanoparticle development.

Ionic liquids-based adsorbents for extraction and separation: A review emphasizing recent advances in sample preparation

Ionic liquids (ILs) exhibit remarkable physical and chemical properties, encompassing negligible vapor pressure, non-flammability, high thermal stability and mechanical robustness. Moreover, ILs can be readily tailored for specific functions by altering the combination of cations and anions. These unique attributes have led to the widespread adoption of ILs as highly efficient adsorbents in sample preparation. To meet the requirements of various applications, ILs are often immobilized or functionalized. This review summarizes the primary types of currently available ILs-based adsorbents, including poly(ionic liquids), ILs-modified silica-based adsorbents, ILs-modified carbon-based adsorbents, ILs@metal–organic frameworks composite adsorbents, and ILs@covalent organic frameworks composite adsorbents. Additionally, the applications of ILs-based adsorbents in sample preparation techniques such as dispersive liquid-liquid microextraction, single-drop microextraction, hollow fiber liquid-phase microextraction, solid-phase extraction, magnetic solid-phase extraction, and solid-phase microextraction are introduced. Furthermore, the review provides insights into the challenges and prospects for the future development of ILs-based adsorbents.

Review of Surface Treatment Technology for Improving Wear Resistance of Magnesium Alloys

Background: As the lightest metal structural material in engineering, magnesium alloy has excellent mechanical properties, such as high specific strength, high specific stiffness, good damping performance, and good machinability. It is widely used in the fields of precision parts, automobiles, aerospace, and military. However, poor friction and wear performance are significant magnesium defects of the alloys, which make its use limited in some areas with high working conditions, so it is essential to improve the wear resistance of the magnesium alloy surface. Objective: The aim of this study was to summarize the technology of improving the wear resistance of magnesium alloy in recent year. The influence of different surface treatment technology for enhancing friction and wear properties was also analyzed, which could provide a reference for related scholars and researchers. Method: In this paper, the literature related to friction and wear properties of magnesium alloys in recent years were reviewed, the principles of various surface treatment technology of magnesium alloys were explained, and the advantages and disadvantages of each technology were analyzed. Results: Based on the literature analyses related to the wear resistance of magnesium alloys, the problems existing in the surface treatment technology for improving the wear resistance of magnesium alloys are summarized, and future development directions are put forward. Conclusion: Among the technologies to improve the wear resistance of magnesium alloys, the combination of various techniques can better meet the working demands. The environmentally friendly and efficient manner has a good prospect for development.

Identification of sport talents through leisure activity: a pathway for achieving football commercialization

ABSTRACT The study identifies how the sport talents of young people are identified through leisure activity, which supports them to achieve professional status. Through recreational specialization and network support, we understand how amateur athletes’ leisure participation evolved through realizing their professional sports dreams. Leisure and recreational specialization studies contribute to explaining players’ progression from their street football activity in communities. Semi-structured interviews and interactions with 19 former African professional players reveal that they relied mostly on networks of recreational intermediaries (e.g. agents, scouts) to reach their recreational specialization, offering them professional sports careers abroad. Former players experienced some challenges through their involvement in leisure behaviour as they sought to commercialize their leisure activity of football for socioeconomic benefit. This paper presents valued evidence for recreational managers or recreational intermediaries to support children’s leisure pursuits in identifying their talents and prospects for development to enhance their livelihood and well-being in the future.

Ultrasonic-assisted DES extraction optimization, characterization, antioxidant and in silico study of polysaccharides from Angelica dahurica Radix

In this study, polysaccharides from Angelica dahurica Radix (ADR) were extracted by using ultrasonic-assisted deep eutectic solvent (DES) extraction method. The DES consist of choline chloride (HBA, hydrogen bonding acceptor) and 1, 4-butanediol (HBD, hydrogen bonding donor) with the molar ratio of 1:3 was proved as the best system for polysaccharides extraction. A Box-Behnken design with three factors and three levels was utilized to optimize ultrasonic power, extraction time and temperature for increased polysaccharides yield. The optimal extraction parameters were determined as follows: DES water content of 20 %, liquid–solid ratio of 10:1 mL/g, ultrasonic time of 21 min, temperature at 60 °C, and ultrasonic power of 435 W. These conditions yielded an extraction rate nearly matching the theoretical predicted value of the response surface model, surpassing the traditional hot water extraction method by 1.33 times and requiring less time. The antioxidant polysaccharides was assessed using DPPH,ABTS and Hydroxyl methods, which indicated that ADRP extracted by ultrasound assisted DES had excellent antioxidant capacity and showed a dose–response relationship with drug concentration. Structural analysis identified ADR polysaccharides as a heteropolysaccharide rich in sugar aldonic acids—namely, fucose, rhamnose, arabinose, galactose and glucose—with molar ratios of 0.47:1.99:17.61:64.76:15.17. The polysaccharides’ number-average molecular weight was determined to be 97.422 kDa, with a weight-average molecular weight of 245.678 kDa. Network pharmacology and molecular docking analysis suggest that the monosaccharides Rha and Ara could potentially interact with the proteins GSR and GSTA1, respectively, indicating that ADRP had good antioxidant potential and could be applied in multiple fields with promising development prospects in the future.

Enhancing the Stereocomplex Crystallization of PLLA/PDLA Symmetric Blend by Controlling the Degree of Molecular Chain Entanglement

In order to enhance the content of stereocomplex crystals (SC) in poly L-lactic acid (PLLA)/poly D-lactic acid (PDLA) symmetric blend, thereby improving the defects of low crystallinity and poor heat resistance of polylactic acid (PLA)-based materials, the samples with different entanglement degrees were prepared by freezing extration method. The critical overlap concentration of the blend system was quantitatively obtained using an Ubbelohde viscometer. Based on this concentration, samples with a series of concentration gradient were prepared to control the different degrees of molecular chain entanglement inside. The results indicated that the chain disentanglement could greatly increase the content of SC in the blend, whether in the precipitation crystallization or the melt crystallization process. Especially after the isothermal crystallization for 30min at 130oC, the L/D-0.1 sample with the highest degree of disentanglement almost only formed SC, accounting for 95.2% of the total crystallinity. Samples with lower entanglement degree had more crystal nuclei and faster growth rate of formed spherulites. For completely entangled sample L/D-50, the crystal nucleus of homo-crystalls (HC) could be considered as SC. Besides, the Vicat softening temperature (VST) of L/D-0.1 sample increased from 79.9oC of L/D-50 sample to 103.8oC with an obvious increase of 24.9oC. All these results provide new ideas for improving the performance of PLA-based materials and show promising development prospects of green and sustainable polymers.