Propolis (bee glue) is a sticky, gummy, resinous substance collected by honeybees from variousplant sources, which has various medicinal properties. This study aimed to know the therapeutic roleof ointment which prepared from extract of local propolis in treatment of external wounds thatexperimentally infected with S.aureus in experimental mice. The ratio of ethanolic extract of propolisamounted (33%) of the weight of the dry substance, it was glutinous with dark green color andcharacteristic odor. Moreover, the results of the preliminary chemical tests which was taken in thisstudy revealed that propolis contains flavonoids, resins, terpenes, and phenols.T tested the qualificationof ethanolic extract of propolis In vivo.Through its prepared as an ointment (9%) in the treatment of externalwounds which are induced in a lab. mice infected with S.aureus the ointment showed high qualificationto treat such wounds (8 days ) compared with control group(15 days ) and a group which treated withvaseline (15 days) that is assured by histopathological sections taken from the infected area before andafter treatment.
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