When hydraulic machines operate away from their design condition, the angle between the inflow and the blade's leading edge increases significantly, causing severe cavitation. To address this, this investigation focuses on cavitation flow around hydrofoil with a high incidence angle. The effects of the vortex generators (VGs) on cavitation evolution, pressure fluctuations, and flow-induced noise were discussed. Experiments and simulations were jointly employed in this work. The results indicate that under current conditions, cavitation initiates upstream of the VGs, closer to the leading edge. The branch-like vortex cavitation induced by the VGs enhances the stability of the shedding cavities in the midstream of the hydrofoil, leading to a 15.24% reduction in the primary frequency of cavitation shedding. With the addition of the VGs, the amplitude of pressure fluctuations on the hydrofoil surface is reduced. Also, the acoustic power drops over the entire spectrum, especially in the high-frequency range. The sound pressure corresponding to the main frequency of cavitation noise is reduced by 7 dB.