Networks of educators are being used in the U.S.A. to promote cancer prevention and treatment clinical trials. These educators are educating the public, patients, and their families about the clinical trials process and what to expect while participating in a trial. Since clinical trials are the most effective tool scientists have to evaluate new approaches to cancer prevention and treatment, the National Cancer Institute has placed a strong emphasis on clinical trials as part of a comprehensive research agenda. Despite the importance of the issues, clinical trials continue to face significant obstacles to producing timely answers. This presentation will describe education and training efforts being coordinated by the National Cancer Institute in collaboration with patient advocates, cancer centers, and professional organizations to increase the number of patients enrolled in clinical trials, nationwide. Special emphasis will be placed on the design and development of a 4-part training program for the target audiences.