Implementation Of Program Research Articles

Effectiveness of a movement and music programme on activity, sedentary, and sleep behaviours and motor and musical skills in young children: protocol for the MoviMusi cluster randomised controlled trial

The early childhood education and care (ECEC) environment is an important setting for providing children with daily opportunities for movement and music, supporting holistic child development in the early years. To date, there are no studies evaluating the implementation of a holistic programme in the ECEC context in the areas of movement behaviour and motor and musical skills. The main aim is to examine the effectiveness of a holistic movement and music programme on physical activity (PA), sedentary behaviour and sleep, motor skills and musical skills in young children (1–3 years). The secondary aims are to examine the impact of the movement and music programme on the perceptions of the educational community, as well as the barriers and facilitators they perceive in the process of baseline assessment, construction, and implementation of the movement and music programme in their own ECEC community. This cluster-randomised controlled trial (intervention and control groups) with public ECEC centres will be performed over a 24-month period. Baseline measurements will be taken in the first year of the project, and assessments to examine the effectiveness of the programme will take place 12 months after the baseline assessment. For young children the main outcome variables will be: (a) PA, sedentary time, and sleep time; (b) gross and fine motor skills; and (c) musical skills. The secondary outcomes will be: (a) PA and sedentary time during outdoor play and structured PA sessions; (b) play patterns during outdoor free play; and (c) movement and music behaviours after ECEC hours. For families, secondary outcomes will be: (a) perceived barriers and facilitators to PA in young children; (b) perceived barriers and facilitators to the inclusion of music at home; and (c) the means of transport to ECEC settings and barriers to active commuting. For ECEC educators, the secondary will be: (a) perceived barriers and facilitators for the inclusion of movement and music as curricular practices in the ECEC institution; (b) perceived impact of the implementation of the movement and music programme. This research project aims to fill a knowledge gap during a period of childhood that has rarely been explored, either nationally or internationally (1–3 years), and to position movement and music teaching practices as key contexts in the curriculum development of infant and toddler education.

Analysis Results and Impact of the Sekolah Penggerak Program at Kolese Xaverius Ambon High School

This study describes the results and impact of the Sekolah Penggerak program at Kolese Xaverius Ambon High School. The focus of the research is four dimensions, including: Sekolah Penggerak program preparation, Sekolah Penggerak program planning, Sekolah Penggerak program implementation as well as results and Sekolah Penggerak program impacts. This research uses a descriptive-analytical approach used to describe in depth research problems to describe descriptively the phenomena that occur in the field. The participants this research were the school principal and deputy head of curriculum. The data collection techniques used were assessment rubrics, observation, free interviews and documentation studies. Data analysis was carried out descriptively (quantitative and qualitative). The results of data analysis in all dimensions obtained the results: 100%+92%+72%+87.5=351.5%/4= 88%. These results are in the category: (75% < The results of the analysis of dimension 1: Driving School Preparation obtained 100% results. These results are in the category (75% < X ≤ 100% = 4) meaning very good. Results of data analysis on dimension 2: Sekolah Penggerak program Arrangement, obtained a result of 92%. These results are in the category (75% < X ≤ 100% = 4) meaning very good. Results of analysis of dimension 3: Sekolah Penggerak program implementation the drive obtained a yield of 72%. These results are in the category (50% < X ≤ 75% = 3) which means good. Results of data analysis on dimension 4: Sekolah Penggerak program results and impact a result of 87.5% was obtained. These results are in the category (75% < X ≤ 100% = 4) meaning very good. The results obtained include: the school principal has become a role model by implementing team leadership, understanding assessment, learning tools, innovative learning models and information technology this has implemented differentiated learning, both content, process and product differentiation. There has been an increase in literacy, numeracy, character and school reports. Perceived impact: Energy used for partner schools, one student Kolese Xavier Ambon High School passing the selection and getting a scholarship to study in the United States, enthusiasm for entering high school, the trend of students graduating and entering their favorite college. Keywords: analysis, Sekolah Penggerak Program, leadership, assessment, school principal

An artificial intelligence-enabled consumables tracking system for medical laboratories

Abstract The medical laboratory plays a crucial role within a hospital setting and is responsible for the examination and analysis of patient specimens to accurately diagnose various ailments. The burden on medical laboratory personnel has significantly increased, particularly in the context of the ongoing global COVID-19 pandemic. Worldwide, the implementation of comprehensive and extended COVID-19 screening programs has placed a significant strain on healthcare professionals. This burden has led to exhaustion among medical employees, limiting their ability to effectively track laboratory resources, such as medical equipment and consumables. Therefore, this study proposed an artificial intelligence (AI)-based solution that contributes to a more efficient and less labor-intensive workflow for medical workers in laboratory settings. With the ultimate goal to reduce the burden on healthcare providers by streamlining the process of monitoring and managing these resources, the objective of this study is to design and develop an AI-based system for consumables tracking in medical laboratories. In this work, the effectiveness of two object detection models, namely, YOLOv5x6 and YOLOv8l, for the administration of consumables in medical laboratories was evaluated and analyzed. A total of 570 photographs were used to create the dataset, capturing the objects in a variety of settings. The findings indicate that both detection models demonstrate a notable capability to achieve a high mean average precision. This underscores the effectiveness of computer vision in the context of consumable goods detection scenarios and provides a reference for the application of real-time detection models in tracking systems within medical laboratories.

The highly pathogenic avian influenza H5N8 sublineage 2.3.4.4b virus: A critical analysis of genetic steadiness based on full HA gene sequencing in Egypt

The highly pathogenic avian influenza virus (HPAIV) continues to be a significant threat to the poultry industry despite the implementation of vaccination programs. The main goal of this study was to explore the incidence of avian influenza viruses (AIVs) and the stability of the hemagglutinating (HA) gene sequence. For this drive, oropharyngeal swabs (n=425) were collected from various wild and domesticated bird species from 13 provinces in Egypt from 2019 to 2021. Viral isolation in specific pathogen-free chicken embryos revealed positive HA activity in 9.88% (n=32) of the wild and 36.37% (n=64) of domesticated species. Only eight H5N8 avian influenza viruses were delivered (4/each category) in mixed infection with Newcastle disease virus (NDV). Clinically, domesticated examined birds exhibited clinical findings suggesting avian influenza, but AIVs were delivered from both apparently healthy and sick wild birds. A/chicken-cobb/Egypt/55/2019(H5N8) sequence generated in this study has been submitted to GenBank under the accession number ON724339, and its in vivo pathogenicity was evaluated in four-week-old chickens, which revealed 90% mortality and typical clinical findings of HPAIV. Based on the full HA gene sequence, the strain has a Furin-sensitive cleavage site in the HA protein, which is an HPAIV. It has been clustered in clade 2.3.4.4b within AIVs from 2016 to 2023 and coexistence of genetically stable viruses 2016-2019 with 99.8-100% similarity. The existing strain is fully identical to three strains: A/green-winged teal/Egypt/877/2016(H5N8), A/northern shoveler/Egypt/MB-D-816OP/2016(H5N8), and A/duck/Egypt/N13736E/2017 (H5N8), with the only point of mutation at position 284 (G284E). In our analysis, the majority of H5NX AIV strains detected in Egypt since 2016 possessed 156T. As a result, there is evidence suggesting that H5N8 has been introduced sequentially through the migration of European wild birds along the Black Sea–Mediterranean and East Asia–West Africa flyways. This raises the possibility of future adaptation to mammals due to spillover from avian-origin strains, especially in native aquatic birds such as geese and ducks.

Kriminalisasi dalam Ketentuan Pidana Pemberian ASI Eksklusif Ditinjau dari Perspektif Keadilan Pancasila

This study aims to describe the internalisation of justice based on Pancasila in the concept of criminalization and analyse the criminal provisions of the exclusive breastfeeding program from the perspective of criminalization based on Pancasila justice. This study is included in normative legal research. The results of the study show that the handling of criminalization must be in accordance with the concept of justice from the Pancasila perspective which contains two main elements, namely proportionality and the principle of kinship to maintain unity. The crime of exclusive breastfeeding programs is related to the denial of obligations carried out by families or corporations to provide time and facilities to support exclusive breastfeeding. Criminal sanctions for actions that do not support the implementation of the exclusive breastfeeding program in the form of imprisonment, fines or additional penalties as regulated in Article 430, Article 447 and Article 448 of Law Number 17 of 2023 are not in accordance with the concept of justice based on the Pancasila perspective because they do not meets the aspect of proportionality and does not reflect the principle of kinship.

Assessment of hygienic-sanitary status and implementation of an integral risk management program in butcher shops from Tafí Viejo city, Tucumán, Argentina

Meat and meat products promote the growth of pathogens such as Shiga toxin-producing Escherichia coli and Salmonella spp. In this work, an evaluation was carried out through risk quantification and microbiological analysis on ground beef and environmental surfaces in butcher shops, of Tafí Viejo city, Tucumán province. The study was carried out in three periods: period 1 (description of the health-status), period 2 (implementation of improvement actions) and period 3 (verification of success). Ground beef samples and environmental surfaces were analyzed in the previously described periods. The improvement actions in each butcher shop were implemented on the deviations detected in the first period. An increase of 35.7 % in low-risk butchers was observed. Microbial indicators in ground beef were significantly lower for total aerobic mesophilic microorganisms and Stapylococcus aureus, compared to the first period. In ground beef samples and environmental surfaces, the detection/isolation of STEC non-O157, presented a 100 % decrease in the verification period. The detection of Salmonella spp. showed a reduction of 14.3 % only on ground beef samples. This study confirms that the implementation of a risk management program in butcher shops would reduce contamination of ground beef and the environment with pathogens.

Leadership Training for Teachers and Students’ Classroom Performance in China

This study investigates the impact of leadership training on teachers' classroom performance and student achievement in the context of Chinese schools. The research aims to address the gap in understanding the specific effects of leadership training on teaching practices and classroom dynamics in China. Drawing upon Transformational Leadership Theory and Social Cognitive Theory, the study explores how leadership training can inspire and motivate teachers, enhance instructional quality, and foster student success. The research indicates that while educational reforms in China have emphasized the professional development of teachers, including leadership training, there is limited empirical evidence on the effectiveness of such programs. The study finds that transformational leadership practices are increasingly prevalent, with positive effects on school culture and teacher motivation. However, challenges persist, such as the gap between theoretical training and practical application, which can hinder the effective implementation of leadership training programs. The study highlights the importance of comprehensive professional development programs that align with teachers' experiences and involve active learning. It also underscores the need for targeted and practical leadership training that directly addresses classroom challenges and enhances teachers' self-efficacy. By examining the impact of leadership training on teaching practices and student performance in Shaanxi province, China, the research provides valuable insights for educators and policymakers. The findings suggest that effective leadership training can significantly contribute to the enhancement of educational quality and student achievement in China.

Implementation of basic education management in Grobogan district: Analysis and model development

Law Number 20 of 2003 on the National Education System states that citizens have the right to obtain basic education for children aged seven to fifteen years. In addition, it is also a commitment to the implementation of Grobogan district’s regional regulation No 5 of 2019 on education implementation, especially article 12 related to the obligation of local governments to ensure the implementation of basic education according to their authority. The purpose of this study is to determine the implementation of the basic education management program in Grobogan district; analyze the factors that support and hinder the implementation of the basic education management program in Grobogan district; formulate a model for implementing the basic education management program in Grobogan district. The method used in this research is qualitative. This method was used to analyse the phenomenon of policy implementation of the basic education management program in Grobogan district. The research site was in Grobogan district. The informants are policy actors who know a lot about the basic education program in Grobogan district. The results show that the implementation of the Grobogan district education office’s policy on basic education management consists of three areas, namely (1) equalization and expansion of access to education; (2) improvement of quality, relevance and competitiveness; (3) education governance and accountability. These three areas aim to achieve the national standards of education and the minimum service standards of education.

Investigation of the Items Prepared by Teachers Who Received Training on Item Preparation Measuring Higher-Order Thinking Skills

This study was conducted to determine how the in-service training program for science teachers affects teachers' competencies in preparing items measuring higher order learning levels. The study was conducted with the exploratory special case design, which is one of the special case study models. The study group consisted of 8 science teachers who participated in the training program implemented within the scope of the study. The training program is an 8-week question preparation training that measures higher-order thinking skills. The training was carried out theoretically and practically by science education, assessment and evaluation and curriculum experts. During the study, the teachers prepared items to measure higher order thinking skills related to the Earth and Universe learning area in the science curriculum for six months. A 21-item checklist developed by the researcher was used as a data collection tool in the study. The data obtained in the scope of the program were analyzed descriptively. The analyses were reported as frequency and percentage, and the results were visualised with graphs. At the end of the program, it was determined that 43% of the items prepared by the teachers measured higher-order thinking skills. This finding suggests that the training program positively affected the teachers' competence in writing items that measure higher-order thinking skills. At the end of the study, a fair number of suggestions were made, the most important being the widespread implementation of the training program.

IMPACTOS DA DEPRESSÃO PÓS-PARTO NA AMAMENTAÇÃO EXCLUSIVA: UMA REVISÃO INTEGRATIVA

Postpartum depression (PPD) is a psychological disorder that significantly affects the mentalhealth of women during the postpartum period, impacting, exclusive breastfeeding (EBF),which should be maintained during the first six months of the baby's life. This study aimed to identify the main symptoms of PPD that can hinder exclusive breastfeeding. The specific objectives included: evaluating the impact of PPD on the duration and exclusivity of breastfeeding; highlighting the influence of PPD on early weaning; and exposing the symptomatology associated with PPD. The methodology used was an integrative review of articles published between 2019 and 2023, analyzing the risk factors related to PPD, as well as the psychological, physical, and social impacts on women. The findings indicate that conditions such as low education levels, socioeconomic vulnerability, and lack of social and maritalsupport are strongly associated with the development of PPD, which directly compromises the mothers' ability to provide exclusive breastfeeding to their children. The results emphasize the importance of early interventions, such as adequate psychological support, family support networks, and awareness actions by healthcare professionals. In conclusion, public policies focused on maternal and child health should be strengthened, with an emphasis on the prevention and management of PPD, aiming to ensure the overall well-being of mothers and their babies. The implementation of antenatal care programs and emotional support can helpreduce the adverse effects of PPD.

Shaping the Quranic Generation from an Early Age (Study of Imtaq Programme Management in PAUD Akbar, Kaur Regency, Bengkulu)

This study discusses the management of the imtaq program at PAUD Akbar. The problems discussed in this study are planning, implementation, and assessment of the imtaq program at PAUD Akbar. This study uses descriptive qualitative research. Data collection techniques include interviews, observation, and documentation studies. Data analysis techniques using data reduction, data presentation, and conclusion drawing. The results of the research are: First, Akbar PAUD has formulated imtaq program planning. The imtaq program is a flagship program because it is in accordance with the need to obtain religious education in line with the vision and mission of PAUD Akbar. Program planning consists of daily, weekly, and annual programs. Secondly, the implementers of the imtaq program include the principal, teachers, parents, and the community who work together in implementing the program. Teachers apply four learning methods, namely, the play method, the storytelling method, the singing method, and the demonstration method. Third, teacher assessment is carried out in the form of assessments on aspects of child development and cognitive, affective, and psychomotor aspects. The assessment is carried out by teachers by conducting observations, children’s self-assessment, and portfolio assessment. The results of the follow-up of the program are still continued, but there are some improvements in improving facilities and infrastructure, teacher competence, and variations in learning models.

Challenges and Opportunities in Establishing a COVID-19 Patient Registry in a Regional Setting in the Philippines

The purpose of this review is to evaluate various challenges and opportunities as well as propose solutions for the development and implementation of a prospective COVID-19 patient registry within a regional context in the Philippines. To comprehensively study the course of COVID-19 in the Philippine population, it is essential to develop a comprehensive dataset that includes relevant treatment and diagnostic information. While individual patient reports related to the disease are available at various institutions in the Philippines, there is a need for a more extensive and representative database to facilitate robust analysis. The primary clinical objective of establishing a COVID-19 patient registry was to enhance the accuracy of disease diagnosis. In this review, we present a comprehensive explanation of the systematic rationale, design, and execution of a COVID-19 patient registry in the Western Visayas region of the Philippines. Based on this review, several factors exist that hinder the implementation of a COVID-19 patient registry in this regional setting in the Philippines, including lack of funding, facilities, infrastructure, manpower, and expertise, and unwillingness of some hospitals to pursue research. We also discussed herewith the proposed program implementation for the establishment of such a registry in a regional setting in the Philippines.

Risks associated with cancer screening programmes among multimorbid patients: a systematic review

Abstract Background Cancer screening programmes have been implemented to facilitate early detection of cancer. However, there are risks associated with cancer screening, such as overdiagnosis. This means identifying problems that were never going to cause harm1. This includes identification of abnormalities that do not progress, or that progress too slowly to cause symptoms or harm during a person’s remaining lifetime in the context of multi-morbidity1,2. Aim We conducted a systematic review of the literature to explore the harms associated with overdiagnosis in multimorbid patients when they undergo three different types of cancer screening programmes. Methods The search was conducted on MEDLINE, EMBASE, PSYCHINFO and Scopus from 1960 (cancer screening programmes implementation) until November 2023. Inclusion criteria involved studies with multimorbid participants (having two or more chronic conditions), having one of three common types of cancers (i.e., breast, prostate and lung), and used a standardised method for screening (i.e., mammography, Prostate-specific antigen test, and Low Dose Computed tomography (LDCT) or Computed Tomography scans (CT)). Only peer-reviewed studies published in English were included. Four keyword sets were used, “Multimorbidity”, “Overdiagnosis “, “Patient harms” and “Cancer screening”. Two independent reviewers conducted the search and data extraction. Rayyan web application was used to help with title, and abstract screening, and to compare the independent reviews. The Newcastle-Ottawa scale was used for quality assessment. This systematic review was registered with PROSPERO database (CRD42024475175) and followed the Preferred Reporting Items for Systematic reviews and Meta-Analysis (PRISMA) guidance. Ethical approval was not required to undertake this review. Results A total of 200 studies resulted from all the databases search and duplicates (n=29) removed. Titles, abstracts and full-texts were screened, with seven studies meeting the inclusion criteria. Quality assessment of the included studies showed two studies of good quality and five studies of poor quality. All included studies were conducted in the United States. Breast cancer overdiagnosis increased with increasing the number of comorbidities. Rates of overdiagnosis with prostate cancer were higher compared to breast cancer, with multimorbid patients having a 15% higher risk of overdiagnosed malignancies, compared to non-multimorbid individuals. Harms of overdiagnosis were categorised into psychological (e.g. anxiety), physical (e.g. side effects of medications) and financial (e.g. costs to healthcare systems). Overdiagnosis with lung cancer was associated with increased anxiety, with more individuals dying from other causes than lung cancer in post-mortem studies, questioning the risk versus benefit of lung cancer screening result interpretation for non-progressive disease. Conclusion The emergence of sophisticated testing technologies and greater access to screening tests can contribute to overdiagnosis. We found many different types of harm related to overdiagnosis in common types of cancer. Further research is required to explore the risk of overdiagnosis with other types of cancer. Awareness of clinicians about the risks of overdiagnosis, particularly in high-risk population, such as multimorbid patients, could guide their decision-making regarding non-progressive cancer treatment.

Effect of the social environment on olfaction and social skills in wild-type and a mouse model of autism

Autism spectrum disorders (ASD) are complex, polygenic and heterogenous neurodevelopmental conditions. The severity of autism-associated variants is influenced by environmental factors, particularly social experiences during the critical neurodevelopmental period. While early behavioral interventions have shown efficacy in some children with autism, pharmacological support for core features — impairments in social interaction and communication, and stereotyped or restricted behaviors — is currently lacking. In this study, we examined how the social environment influences both wild-type (WT) and Shank3 knockout (KO) mice, a model reflecting core autism-like traits. Our findings revealed that chronic social isolation enhanced social interaction and olfactory neuron responses in WT animals. Furthermore, it restored impairments in social novelty preference and olfactory function, as well as self-grooming in Shank3 KO mice. Conversely, an enriched social environment heightened social interest toward novel conspecifics in WT mice, but elicited the opposite effect in Shank3 KO mice. Notably, Shank3 KO mice displayed distinct social responses when exposed to WT or Shank3 KO mice. These results offer novel insights that could favor the implementation of behavioral interventions and inclusive classroom programs for children with ASD.

Implementation of clinical breast examination screening programme as part of primary care in Vietnam: An analysis of contextual factors

Implementation of clinical breast examination screening programme as part of primary care in Vietnam: An analysis of contextual factors

Global Epidemiology of Meningococcal Disease-Causing Serogroups Before and After the COVID-19 Pandemic: A Narrative Review.

Invasive meningococcal disease (IMD) is associated with high morbidity and mortality and predominantly caused by five Neisseria meningitidis serogroups (A/B/C/W/Y). Polysaccharide conjugate vaccines induce T-cell-dependent immune responses, are immunogenic in infants and adults, and reduce carriage, and vaccination of age groups associated with high-carriage can provide indirect protection in the unvaccinated (herd immunity). Successful vaccination programs must be tailored to local epidemiology, which varies geographically, temporally, and by age and serogroup. Serogroup A IMD once predominated globally, but has largely disappeared following mass vaccination programs. Serogroup B was a predominant cause of IMD in many global regions from 2010 to 2018, typically affecting younger age groups. Spread of serogroup C clonal complex-11 IMD in the 1990s prompted implementation of MenC vaccine programs in many countries, resulting in declines in prevalence. Serogroup C still caused>20% of global IMD through the mid-2010s. Serogroup W became a significant contributor to global IMD after Hajj pilgrimage outbreaks in 2000; subsequent increases of endemic disease and outbreaks were reported pre-pandemic in many regions. Serogroup Y emerged in the 1990s as a significant cause of IMD throughout various regions and prevalence had increased or stabilized from 2010 to 2018. Serogroup X is uncommon outside the African meningitis belt, and its prevalence has declined since before the COVID-19 pandemic. Global IMD declines during the pandemic were followed by resurgences generally caused by serogroups that were prevalent pre-pandemic and affecting mainly unvaccinated age groups (particularly adolescents/young adults). Recent IMD epidemiology underscores the importance of vaccinating at-risk age groups against regionally prevalent serogroups; for example, the anti-serogroup X component of the recently prequalified MenACWXY vaccine is likely to provide limited protection outside the African meningitis belt. In other regions, comprehensive vaccination against MenB and MenACWY, which could be streamlined by the recently approved MenABCWY vaccine, seems more appropriate.

Return on Investment of Preoperative Anemia Management Programs in Cardiac Surgery: An Advisory From the Society of Cardiovascular Anesthesiologists Clinical Practice Improvement Committee With Endorsement by the Society for the Advancement of Patient Blood Management

Despite multiple recent guidelines recommending the diagnosis and treatment of anemia before elective cardiac surgery, few institutions have formal programs or methods in place to accomplish this. A major limitation is the perceived financial shortfall and the leadership buy-in required to undertake such an initiative. The purpose of this advisory from the Society of Cardiovascular Anesthesiologists (SCA) Clinical Practice Improvement Committee with endorsement by the Society for the Advancement of Patient Blood Management (SABM) is to provide an overview of preoperative anemia management programs with an emphasis on the associated financial implications. This advisory reviews the evidence for preoperative anemia management programs in both cardiac and noncardiac surgery, discusses options for managing preoperative anemia, provides novel financial modeling regarding the implementation of preoperative anemia management programs, and describes implementation challenges, potential solutions, and opportunities for improvement.

Overview of CHIC symposia series: Summary of Africa and South Asia symposia

This article presents an overview of the main challenges and lessons learned that were presented during the symposia organized by the Coalition to Strengthen the HPV Immunization Community (CHIC) in Africa and South Asia in 2022. Discussions at these meetings revolved around introduction, planning, implementation, and sustainability of HPV prevention and control programmes, with a particular focus in HPV immunisation, as well as cervical cancer screening in South Asian countries. This article also discusses the recently endorsed off-label single-dose HPV vaccination schedule and its potential impact on programme delivery and access. Furthermore, it highlights the importance of intersectional collaboration, effective communication and advocacy strategies, and the need for robust health information systems. Some of the critical factors identified for reducing the burden of cervical cancer in low- and middle-income countries (LMICs) included strategies for increasing access and coverage, addressing vaccine hesitancy, and building capacity among health care providers. The symposia emphasized the importance of face-to-face interactions for collaboration and decision making, with live translation services enabling full participation by stakeholders from diverse backgrounds. The paper concludes with a call for continued collaboration to make progress in reducing the burden of cervical cancer in LMICs.

Features of reproductive function and IVF programs in patients with overweight and obesity

Obesity is a chronic multifactorial heterogeneous disease characterized by high prevalence, progressive increase in morbidity, high cardiometabolic risk. The prevalence of obesity is increasing from year to year and does not tend to decrease. Up to 60% of women of reproductive age are overweight, and a quarter of them are obese. In addition to cardiovascular pathology, type 2 diabetes, gastrointestinal diseases, oncological processes, obesity can affect the reproductive function of women, reduce fertility and be an independent cause of infertility, as well as reduce the effectiveness of assisted reproductive technology programs. This paper analyzes studies on the problem of reproductive system disorders, the effectiveness and safety of assisted reproductive technology programs in patients with overweight / obesity. The review includes data from foreign and domestic articles in the Pubmed, Elsevier, Cochrane Library, e_library databases published over the past 10 years. As a result of the analyzed publications, it was concluded that the implementation of IVF programs in patients with overweight/obesity presents certain difficulties at each stage of the program: the duration and cost of ovarian stimulation increases, the number and quality of the obtained oocytes and embryos decreases, the displacement of the “implantation window” is more often noted, decreased endometrial receptivity, which together causes a decrease in the pregnancy rate (PR) in this category of patients. It should be noted that in women with visceroabdominal obesity, with more pronounced metabolic abnormalities – dyslipidemia, carbohydrate metabolism disorders, reproductive disorders are expressed to a greater extent than in patients with a more favorable femoral phenotype type of obesity, which requires an individual approach to the treatment of infertility using IVF methods depending on the clinical and etiopathogenetic category of patients.

From subsidies to nutrition: Investigating effects among cohort children from the Subsidy Reinvestment programme in Nigeria

This study investigates the effect of a nationwide maternal health programme that targets both demand- and supply-side factors on the nutritional status of children under five years old whose mothers were potentially exposed to the programme. We employed a difference-in-differences approach by matching programme beneficiary facilities to the districts and communities where households reside. The data are drawn from the 2008, 2013, and 2018 rounds of Nigeria's Demographic and Health Surveys (DHS), comprising responses for approximately 120,000 children. Our findings reveal a significant increase in child dietary diversity, particularly in districts with two beneficiary facilities, suggesting stronger effects with expansive programme implementation. Additionally, we observed positive effects on children's consumption of various nutritious foods for those children in districts with two beneficiary facilities. This study investigates a potential mechanism by which expanding access to healthcare facilities, through funding two clinics per district, may contribute to improved child dietary diversity. Our findings suggest that, unlike districts with one beneficiary facility, those with two funded clinics have a higher likelihood of women engaging in work outside the home and earning cash for it. As shown in the analysis, this mechanism is likely due to easier access to health facilities and better contact with health officers, which facilitate quicker reintegration into the labour market for mothers after childbirth and, in turn, could lead to better maternal earnings and potentially enable a more diverse diet for children. The findings suggest that SURE-P's expansive implementation strengthens child nutrition outcomes and supports maternal economic empowerment. In areas with multiple SURE-P facilities, increased access to healthcare enables mothers to reintegrate into the labor market more quickly, facilitating cash income and fostering a reinforcing cycle of improved child dietary diversity and economic benefits for families. This highlights the potential of scaling such programs to maximize both health and economic outcomes in similar contexts.