Profile Of Urinary Tract Infection Research Articles

Clinico-Microbiological Profile of Urinary Tract Infections in Patients with Type 2 Diabetes: A Study Based in a Hospital Dedicated to Diabetes Care

Introduction: People with diabetes are prone to urinary tract infections (UTIs). The inappropriate use of antibiotics can lead to the development of multidrug-resistant infections, prolonging patient recovery and significantly increasing healthcare costs. In a hospital focused on diabetes care, it becomes important to ascertain the clinical and microbiological profiles to develop appropriate institutional infection control protocols for managing such patients more effectively on an empirical basis; for this purpose, a pilot study was conducted through a representative sample. Methods: The study included randomly selected 60 patients with UTI: 25 patients were from the wards of the hospital and 20 patients were from the intensive care unit, of whom 10 had complicated UTI with multi-organ dysfunction. The remaining (n = 15) were from the outpatient clinic. Microbiological, and where possible, clinical parameters were studied. Results: The mean age of the subjects was 67.12 ± 9.84 years and the female-to-male ratio was 38: 22; 37 of the 38 women were postmenopausal. The mean duration of diabetes was 15.20 ± 7.93 years. Fifty subjects (83%) had an HbA1C >7%. Thirty-eight (63%) had recurrent UTI episodes. Four (6.7%) were on sodium glucose 2 transport inhibitors and estimated glomerular filtration rate (eGFR) was below 60 mL/min/1.73 m2 in 39 cases (65%). Escherichia coli was the most commonly isolated (59.7%), followed by Klebsiella pneumoniae (25.8%). Amikacin was the most effective antibiotic (86.7%), followed by imipenem, piperacillin–tazobactam, and meropenem. Eleven (18%) required ureteric stenting. Conclusion: In our study, people with diabetes have unique nature of UTI, characterized by predisposition to postmenopausal women, high need for urological procedures and a strong link to low eGFR, older age, long duration diabetes, and high HbA1C. Amikacin could be the choice of antibiotic on empirical basis for inpatient setting, whereas nitrofurantoin could be the preferred oral antibiotic. Taking cognizance of these results, the study emphasizes the need for specialized infection control programs and guidelines for diabetes care settings.

Clinical Profile Of Urinary Tract Infection In Neonates With Suspected Sepsis: Efficacy Of Dipstick Testing As A Diagnostic Tool

Clinical Profile Of Urinary Tract Infection In Neonates With Suspected Sepsis: Efficacy Of Dipstick Testing As A Diagnostic Tool

Antimicrobial profile of urinary tract infections at a tertiary care teaching hospital of Central India

Antimicrobial profile of urinary tract infections at a tertiary care teaching hospital of Central India

Epidemiological and Bacteriological Profile of Urinary Tract Infections Diagnosed at The Bacteriology Laboratory of the Centre Hospitalier Universitaire De Fann, Dakar from January 1er to December 31 2020

Introduction Urinary tract infections are extremely frequent and caused by bacteria whose treatment is based on the administration of antibiotics. The emergence and spread of acquired resistance mechanisms are limiting the indications for a number of antibiotics. It is in this context that this work is set, the main objective of which is to study the epidemiological and bacteriological profile of urinary tract infections at the CHNU de Fann, Dakar. Methodology: This is a retrospective study covering a one-year period from January 1er to December 31 2020. All patients received at the laboratory for an ECBU request were included. Data collection was based on information sheets and bench registers. The following information was collected : age, sex, germ isolated, antibiotic susceptibility profile. These data were processed using R. Studio software version 3.6.3, 2019. Results : We received 3697 requests for bacteriological examination of urine. The mean age of patients in our series was 48.7 years, with extremes of 15 days and 113 years. The 60 to 80 age group was the most affected. Women were more affected, with a rate of 51.03%, compared with 48.97% for men. A total of 3,697 urine samples were received during the study period, of which 776 were positive after analysis, representing a rate of 21%. 845 bacteria, with enterobacteria predominating (73.14%), followed by Gram-negative non-fermentative bacilli (13.37%) and Gram-positive cocci (13.27%). Escherichia coli was the most prevalent species, with a frequency of 36.09%, followed by Klebsiella pneumoniae (17.99%), Pseudomonas aeruginosa (8.16%), Staphylococcus aureus (6.63%), Enterobacter spp (6.50%), Citrobacter spp (4.02%), Acinetobacter spp (3.73%), Streptococcus spp (3.67%).Enterobacter spp (52.72%), Escherichia coli (47.53%) and Klebsiella pneumoniae (49.34%) showed a high prevalence of ESBL. Staphylococci showed a high rate of resistance to methicillin (55.71%).

Descriptive Study of the Urinary Tract Infections in Patients Admitted in the Cardiology Ward of Afghan Momand Medical Complex

Urinary Tract Infection (UTI) is very common in our community most specifically in married females with numerous antecedent risk factors. The aim of the study was to find out about the current risk factors and clinical profile of urinary tract infections in patients admitted to the cardiology ward of Afghan Momand Medical Complex for various purposes. It was a cross-sectional descriptive hospital-based study including both male and female patients visiting the Afghan Momand Medical Complex from January 2022 to June 2022. Of all 960 patients, 202 (21%) patients had urinary tract infections with gender distribution as 69 (34.2%) males and 133 (65.8%) females. In fact, 33 (16.3%) patients with urinary tract infections were single while the rest 169 (83.7%) patients were married. In addition, regarding clinical profile, the following clinic was respectively more prevalent: Dysuria in 120 (59.4%) patients, flank pain in 73 (36.1%) patients, urine frequency in 67 (33.1%) patients, urgency in 36 (17.8%) patients, fever in 24 (11.8%) patients, and nausea and vomiting in 19 (9.4%) patients. Moreover, the following risk factors were respectively the most common ones: Diabetes mellitus 86 (42.5%), pregnancy 30 (14.9%), stones 15 (7.4%), 10 (4.9%) devices, 10 (4.9%) prostatic hyperplasia, and 4 (2%) anatomical anomalies. Urinary tract infection is a common disease in the admitted patients in Afghan Momand Medical Complex specifically being more common in females and early 20s of the age. In fact, diabetes, pregnancy, and kidney stones were the leading associated factors with UTI. Moreover, dysuria, bladder emptying irritative symptoms, and abdominal pain were the most prevalent clinical profile of the patients. Special attention should be paid to infectious diseases in cardiac patients since infection itself is a stress and a threat to such patients and authorities should design special measures to prevent UTI in the general population to avoid a sum of burden on the health system.

Bacteriological and Antibiotic Susceptibility Profile of Urinary Tract Infection among Online Motorcycle Drivers in Jakarta, Indonesia

Bacteriological and Antibiotic Susceptibility Profile of Urinary Tract Infection among Online Motorcycle Drivers in Jakarta, Indonesia

Perfil de los pacientes pediátricos con diagnóstico de infección de vías urinarios en el Hospital Departamental Universitario del Quindío San Juan de Dios entre 2017 y 2019

Objective: Urinary tract infection is the second most frequent infectious pathology in childhood. This study seeks to establish the clinical and microbiological profile of urinary tract infections in pediatric patients at the Hospital Departamental Universitario del Quindío San Juan de Dios.
 Materials and methods: Retrospective descriptive observational study. By reviewing the medical records of patients between 0 and 16 years old with a diagnosis of urinary tract infection. Clinical, paraclinical and microbiological variables were obtained. An exploratory analysis was initially performed, followed by a multivariate analysis.
 Results: Data from 200 patients were included, predominantly female and infants patients. The main symptom at the time of consultation was fever. The main pathogen causing the infection was E. coli. The most used antibiotic was Amikacin (60.7%). ESBL was the most commonly found resistance profile (42.5%). 11 patients required antibiotic therapy guided by antibiogram, Amikacin being the most used (41.7%).
 Conclusions: Escherichia coli is the most isolated microorganism, presenting a low profile of bacterial resistance, which allows a better orientation of empirical antibiotic therapy. Amikacin was the most widely used antibiotic, showing very low resistance rates. Longer-duration regimens showed similar characteristics to shorter-duration regimens, which could support shorter regimens, but higher studies are required to prove this.

Epidemiology and Antibiotic Resistance of Enterobacteriaceae Isolated in Urinary Tract Infections at Oued Eddahab Military Hospital Agadir

Objective: Determine the current bacteriological profile of urinary tract infections and the antibiotic resistance of the main enterobacteria isolated in urine. Methods: Retrospective study over a period of 18 months from January 1, 2022 to June 30,2023 including all urinary cytobacteriological examinations of patients hospitalized in the various departments of the Oued Eddahab Military Hospital in Agadir, as well as outpatients. Results: Out of 4483 urine samples, 487 met the criteria for UTI (10.86% of total samples). The microorganisms were predominantly Enterobacteriaceae (421/487 86.44%). Of the infections, 75% originated from outpatients. The sex Ratio F/M was 1.35. E.Coli dominated the epidemiological profile for both inpatients and outpatients (63% vs. 77%). There was a high frequency of resistance to the main families of antibiotics, while quinolones, fosfomycin, nitrofurans, and aminoglycosides retained good activity. Resistance to third-generation cephalosporins through the production of extended-spectrum betalactamase was present in 09% of Enterobacteria. Finally, no resistance to imipenem and colistin was detected.

Clinical and Bacteriological Profile of Urinary Tract Infection in Children; A Tertiary Care Hospital Experience

Clinical and Bacteriological Profile of Urinary Tract Infection in Children; A Tertiary Care Hospital Experience

Bacterial profile of urinary tract infection among pregnant women: a systematic review

Urinary tract infection (UTI) is the infection and colonization of microorganisms in the urinary tract. Women carry a higher risk of being affected by UTI compared to males, especially during pregnancy due to physiological and hormonal changes. Appropriate and adequate management of UTI reduces the incidence of further maternal and fetal complications. Nonetheless, there is a growing concern regarding resistance to antibiotics among the bacteria causing UTIs in pregnant women. To identify the bacterial profile of UTIs during gestation by exploring the previous research conducted on this subject. A systematic online search was performed on scientific databases to obtain articles related to the current subject using search terms, including bacteria, profile, causative agent, sensitivity, resistance, symptomatic, pregnancy, gestation, and pregnant women. The articles of relevance were considered if they were original articles, written in the English language, available for full-text, and reporting bacterial profile of UTI during pregnancy. A total of eight articles were eligible and met the inclusion criteria. The studies were published between 2020 and 2023 and included a total number of 3,702 pregnant females from five different countries. The bacterial profile of UTI among pregnant women including symptomatic UTI, and resistance and sensitivity of bacteria to antibiotics varied between different regions. However, the causative agents of UTI displayed less variation as Escherichia coli and K.pneomniae were the major causative agents of UTI during pregnancy.

Bacterial profile, their antibiotic susceptibility pattern, and associated factors of urinary tract infections in children at Hiwot Fana Specialized University Hospital, Eastern Ethiopia.

Urinary tract infections (UTIs) are common pediatric infections and contribute to high morbidity and mortality. At present, the antimicrobial resistance emergency has quadrupled worldwide and poses a serious threat to the treatment of patients. However, there have been few studies on UTIs in children in Ethiopia, particularly in the east. This study aimed to assess the bacterial profile of urinary tract infections, their susceptibility to antimicrobial agents, and associated factors in under-five children at Hiwot Fana Specialized University Hospital, eastern Ethiopia. We conducted hospital-based quantitative study on 332 consecutively selected under-five children from March 20 to June 10, 2021. Parents and guardians were interviewed to collect data using a structured questionnaire. Random urine samples were collected aseptically, and standard microbiological techniques were used to identify the bacteria and test for susceptibility to various antibiotics. Data were entered into Epi Info version 7 and exported to Statistical Package for the Social Sciences (SPSS) version 25 for analysis. Data were analyzed using descriptive analysis, bivariate, and multivariable logistic regression analysis. The crude odds ratio (COR) and adjusted odds ratio (AOR) with their respective 95% confidence intervals (CI) were used to determine the significance of the predictors. A p-value at a 95% confidence interval of less than 0.05 was considered statistically significant. The overall prevalence of bacterial urinary tract infections was 80 (24.1%) 95% CI:19.40-29.00%). Most of the bacterial isolates 55 (68.75%) were gram-negative bacteria, predominantly E. coli 23 (28.75%) and K. pneumoniae 10 (12.50%). Being a rural resident (AOR: 4.10, 95%CI: 1.45 11.54), uncircumcised male (AOR: 3.52, 95%CI: 1.33, 9.39), previous history of antibiotic usage (AOR: 7.32, 95%CI: 2.11, 25.37), indwelling catheterization (AOR: 10.35, 95%CI: 3.74, 28.63), previous history of urinary tract infections (AOR: 5.64, 95% CI: 1.36, 23.38), and urinary frequency (AOR: 5.56, 95%CI: 2.03, 15.25) had higher odds of culture positive result. The majority of the isolates have shown high levels of antibiotic resistance. Meropenem, ciprofloxacin, and amoxicillin-clavulanic acid were effective against gram-negative uropathogens, whereas rifampin and ciprofloxacin were the most sensitive drugs for gram-positive isolates. From the tested bacterial isolates, 53/86 (61.6%), 11/86 (11.6%), and 2/86 (2.3%) were found to have multidrug resistance (MDR), extreme drug resistance (XDR), and pan drug resistance (PDR), respectively. About one-fourth of the children were culture-positive for many types of bacterial uropathogens; this is higher compared with most of the previous studies in Africa. Rural dwellers, uncircumcised males, indwelling catheterization, a history of antibiotic use and urinary tract infection, and frequent urination all had a higher risk of bacterial infections. Many isolates were resistant to multiple drugs, primarily beta-lactams. Urinary tract infections as well as the growth and spread of resistant bacterial pathogens should be monitor regularly.

Epidemiological, Clinical, Bacteriological Profile of Urinary Tract Infection in the Internal Medicine Unit of the Fousseyni Daou Hospital in Kayes

Introduction: Urinary tract infection is one of the most frequent public health problems in the world and concerns all ages. Objective: To describe the epidemiological, clinical and biological profile of urinary tract infection in the internal medicine unit of the Fousseyni Daou hospital in Kayes. Methodology: It was a descriptive and cross-sectional study with retrospective data collection which took place from January 1 to December 31, 2020 at the Internal Medicine Unit of the Fousseyni Daou Hospital in Kayes. It covered all outpatients and hospitalized patients presenting with a urinary tract infection during the study period. Results: We identified 79 cases of urinary tract infection out of 145 requests for ECBU, that is a positivity rate of 53.10% and out of a total of 1883 admissions that is a hospital prevalence of 4.19%. The age groups of 36 to 45 years and 46 to 55 years were more represented in 28 cases (35.44%) and 25 cases (31.64%) with an average age of 45 years ± 10. The female sex was predominant, 42 cases (53.16%) with a sex ratio of 0.88. Housewives were more represented 28 cases (34.44%). The majority of patients resided in rural areas 49 cases (62.03%). The history was dominated by the following pathologies: hypertension 48.10%, diabetes 36.70% and gastropathy 30.37%. The main clinical manifestations were: Urinary burning 67 cases (84.81%), Dysuria 65 cases (82.27%), Pelvic pain 59 cases (74.68%), Fever 57 cases (72.15%). The epidemiological profile of the isolated strains was dominated by enterobacteriaceae, followed by gram-positive cocci and gram-negative bacilli. The main bacteria responsible for urinary tract infections in order of frequency: Escherichia coli (45.56%), Klebsiella pneumoniae (11.39%), Pseudomonas aeruginosa (8.86%), Staphylococcus aureus (7.59%), Streptococcus sp (6.33%), Enterobacter cloacae (3.79%), Acinetobacter sp (3.79%). The study of the susceptibility and resistance profiles of the isolated strains showed significant sensitivity of enterobacteriaceae to colistin and resistance to amoxicillin and to the amoxicillin + clavulanic acid combination. Conclusion: Urinary tract infections are a major public health problem since they are responsible for significant morbidity and mortality and a high cost of care. Knowledge of the epidemiological-clinical and bacteriological profile of these infections is essential for efficient management.

Microbiological Profile of Urinary Tract Infections in Males: A Cross-sectional Study

Introduction: Urinary Tract Infections (UTI) are uncommon among men. It is because the male urethra is longer and is away from the anal opening. Moreover, the perianal area is dry, and the prostatic secretion prevents from occurring of any infection. Hence, if men suffer from UTI, it is considered as a complicated infection. Complicated UTIs are difficult to treat and are more prone to treatment failures. Microorganisms causing these infections have a wide spectrum ranging from a variety of both Gram-negative and gram-positive organisms. Early diagnosis and treatment of UTIs, plays a major role in preventing the spread of infection to the upper urinary tract. Aim: To determine the microbiological profile and antibiotic sensitivity pattern from urine samples of male patients. Materials and Methods: The present cross-sectional study was done for a period of two years (1/3/2019-31/4/2021) in the Department of Microbiology, Malla Reddy Institute of Medical Sciences and Research, Jeedimetla, Hyderabad, Telangana, India. Urine samples from male inpatients and outpatients suffering from various clinical conditions received in the microbiology laboratory were processed and analysed. These samples were cultured by conventional semi-quantitative methods and the organisms were identified using standard biochemical reactions. Antibiotic sensitivity testing was done on Mueller Hinton agar by Kirby Bauer’s disk diffusion technique. Clinical history, associated conditions, and comorbidities were noted from the case sheets of all the culture-positive patients to identify the risk factors which made them prone to UTIs. The data was descriptive and percentages were calculated for all the numerical data obtained. Results: Out of 304 urine samples received, 104 (34%) were found to be positive for bacterial and fungal isolates. E.coli (44%) was the predominant organism, followed by Klebsiella spp (15%) among the Gram-negative bacteria isolated. Coagulase-negative Staphylococcus (5%) was the predominant organism among the gram-positive bacteria followed by Staphylococcus aureus (4%) and Enterococcus spp (4%). 84.8% of E.coli and 68% of Klebsiella spp were Extended Spectrum Beta Lactamase (ESBL) enzymes producing organisms. An analysis of the health conditions of the patients who were culture positive showed that 28% of patients had signs and symptoms suggestive of UTI. Diabetes (25%), Hypertension (20%), and Benign Prostatic Hypertrophy (BPH) (5%) were observed commonly in patients above 60 years. Conclusion: UTI in male patients are quite uncommon as in female patients. The microbiological profile and drug sensitivity pattern of these organisms causing the infection is similar to that in female patients suffering from UTI. But, as UTI in males is considered a complicated infection thorough investigation of these patients for various health conditions like diabetes mellitus, hypertension, and BPH has to be done, particularly in elderly males. This helps in initiating prompt treatment to prevent recurrent UTIs and drug resistance.

Clinical and Pathological Profile of Urinary Tract Infection in Children and Adolescents; A Hospital Based Study

Background: Urinary tract infections (UTIs) encompass a wide array of infections, accounting for a vast number of community as well as hospital-acquired infections. Aim of the Study: The aim was to analyse the clinical presentation of UTI in children and Adolescents between 6 year to 18 years of age and to analyse the causative microorganism and their drug susceptibility in urinary tract infection in children and Adolescents of the above age group. Methods: This retrospective was conducted at the Department of Pediatrics in Bangladesh Shishu Hospital, Dhaka, Bangladesh. A total of 51 patients were enrolled and analyzed in this study based on culture-positive urine isolates. The study duration was September 2021 to August 2022. The ethical committee of the institution approved the study protocol. Antimicrobial susceptibility was done for positive urine culture by the Kirby-Bauer disk diffusion method. Statistical analysis was done using Statistical package for social sciences (SPSS) software version 16. Result: This is a retrospective study; 98 children were enrolled and analyzed. The majority of the study population was aged 6-10 years (62.75%), 11(21.57%) patients were from the age group 11-15 years, and 8(15.69%) patients were from the age group 16-18 years. Conclusion: The most common clinical presentations of UTI in admitted patients are fever, dysuria and abdominal pain. Gram-negative bacilli were found to be responsible for UTI, and the most frequently isolated bacteria were E-coli.

A Study On Clinical Profile of Urinary Tract Infection in Diabetes Mellitus in a Tertiary Care Hospital

Background: Diabetic Patients are at high risk of developing various infections especially if the diabetes is uncontrolled. Urinary tract infections (UTI) are one of the common infections in diabetics. Knowledge about the clinical and microbiological profile of UTI in diabetic patients will not only aid in early diagnosis but also helps in early initiation of appropriate empirical antibiotic therapy ensuring early recovery. Material & Methods: Prospective hospital based observational study. The study was conducted in the In-patient department, Department of General medicine at KMCT Medical college, Manassery, Kozhikode, Kerala, India. This study was conducted in 170 Diabetic patients above 18 years of age with symptoms of UTI with significant pyuria who were admitted under department of General Medicine, KMCT medical college, Kerala, who satisfied the inclusion criteria and gave consent for study. study consisted a total of 170subjects. Simple Random sampling method. Results: Fever was the most common clinical presentation followed by dysuria. E. coli was the most commonly isolated organism followed by Klebsiella. Most of the organisms were sensitive to Amikacin. Antibiotic resistance and Pyelonephritis were higher in patients with poor glycaemic control. The most common ultrasonographic abnormality was prostatomegaly. Conclusion: Patients with poor glycaemic control are at high risk of resistant UTI and Pyelonephritis. Good glycaemic control with routine monitoring of HbA1C is mandatory in diabetic patients to prevent UTI and to avoid its complications. E. coli was the most common organism isolated followed by Klebsiella. Most of the organisms were sensitive to Amikacin. Hence, Amikacin can be recommended as empirical antibiotic forDiabetic patients who are admitted with UTI.

Bacteriological profile of urinary tract infections in type-2 diabetes mellitus patients in a tertiary care hospital

Bacteriological profile of urinary tract infections in type-2 diabetes mellitus patients in a tertiary care hospital

Epidemiological and Clinical Profile of Urinary Tract Infections in Patients with Percutaneous Nephrostomy Tubes, About 117 Cases

Epidemiological and Clinical Profile of Urinary Tract Infections in Patients with Percutaneous Nephrostomy Tubes, About 117 Cases

Clinical and microbiological profile of urinary tract infection in children less than twelve years of the age and their antibiotics resistant pattern at a Tertiary Care Hospital in Kanpur, India

Background: Urinary tract infection (UTI) is the most common bacterial infection which is seen in childhood population, which starts from the calyces of the kidney to the urethra. It is an important cause of morbidity and mortality in children mostly in the first 2 years of life. The Gram negative enteric bacilli, especially Escherichia coli and Klebsiella spp. the dominant pathogens. The objective of the study was to analyze the causative microorganism and their Antibiotic Resistance Pattern in UTI in childhood population between 0-12years of the age. Methods: This one year prospective and observational study was conducted in the Department of Microbiology; Rama Medical College Hospital & Research Centre Kanpur, Uttar Pradesh, India, on 100 pediatric patients (aged 0-12 years). All the pediatric age group (0-12 years) with suspected UTI and, whose urine culture showed one or two pathogen with colony counts greater than or equal to 105 colony forming units (CFU)/ml was included for the study. Clinical data was obtained from OPD and IPD Patients. Antimicrobial susceptibility was done for positive urine culture by Kirby-Bauer disk diffusion method. The data was expressed in terms of frequency and percentage.

Bacteriological Profile and Antibiotic Resistance Pattern in Children with Urinary Tract Infection in a Tertiary Care Hospital

Introduction: Urinary tract infection (UTI) is one of the most common bacterial infections seen in children. The knowledge of bacterial causes of UTIs and their antimicrobial resistance patterns may help clinicians in choosing the appropriate antimicrobials.
 Objectives: The present study was designed to find out the bacteriological profile of urinary tract infection and their antibiotic resistance pattern in children.
 Methodology: A cross sectional study was done in the department of Microbiology, Sir Salimullah Medical College from January to December 2019. Midstream urine samples were collected from clinically suspected cases of UTI in the age group of 0 to 18 years from various indoor and outdoor patients of Mitford hospital for this study.
 Results: Out of 2763 cases, 363 were culture positives, where females were 202(55.65%) with highest number of cases within the age group of 0 to 4 years (63.36%). Most common isolate identified was Escherisia coli, followed by Pseudomonas, Proteus, Morganella and only Gram positive bacteria was S. aureus. Organisms show highest resistance to Amoxiclav, Cefixime, Cotrimoxazole, Ciprofloxacin and highest sensitivity to Amikacin.
 Conclusion: This study revealed that UTI was more common in female & under five children. Escherichia coli were the commonest isolated organism and all isolates show high resistance to common antimicrobial agents.
 Sir Salimullah Med Coll J 2021; 29(2): 112-116

Bacteriological profile of urinary tract infections and antibiotic susceptibility of Escherichia coli in Algeria.

Background and Objectives:Urinary tract infections are one of the most common bacterial infections worldwide. The emergence of antibiotic-resistant bacterial strains is a serious problem and greatest challenge in public health care. The purpose of this study was to determine the prevalence of uropathogenic microorganisms and the antibiotic resistance pattern of Escherichia coli in Algeria.Materials and Methods:Urine samples were collected from 760 outpatients in the hospital of Tizi-Ouzou (Algeria). From the positive cultures, 120 strains of E. coli were isolated and tested for their susceptibility to antibiotics by disk diffusion method on Mueller Hinton agar medium.Results:Among the collected urine specimens, 270 (35.5%) yielded positive cultures for urinary tract infection. Females were more affected with a sex ratio F/M of 1.14. E. coli was the most prevalent isolated bacteria with a rate of 44.44%, followed by Klebsiella pneumoniae (12.21%), Pseudomonas aeruginosa (11.1%) and Proteus mirabilis (5.55%). Isolates of E. coli showed high level of resistance to cephalothin (85.83%), ticarcillin (82.5%), ampicillin (73.3%) and amoxicillin-clavulanic acid (58.33%). Imipenem was the most effective antimicrobial agent.Conclusion:These results highlight the inappropriate utilization of antibiotics and suggest the need to improve prescription practices in our country.