Organizations adopt blockchain technologies to provide solutions that deliver transparency, traceability, trust, and security to their stakeholders. In a novel contribution to the literature, this study adopts the technology-organization-environment (TOE) framework to examine the technological, organizational, and environmental dimensions for adopting blockchain technology in supply chains. This represents a departure from prior studies which have adopted the technology acceptance model (TAM), technology readiness index (TRI), theory of planned behavior (TPB), united theory of acceptance and use of technology (UTAUT) models. Data was collected through a survey of 525 supply chain management professionals in India. The research model was tested using structural equation modeling. The results show that all the eleven TOE constructs, including relative advantage, trust, compatibility, security, firm’s IT resources, higher authority support, firm size, monetary resources, rivalry pressure, business partner pressure, and regulatory pressure, had a significant influence on the decision of blockchain technology adoption in Indian supply chains. The findings of this study reveal that the role of blockchain technology adoption in supply chains may significantly improve firm performance improving transparency, trust and security for stakeholders within the supply chain. Further, this research framework contributes to the theoretical advancement of the existing body of knowledge in blockchain technology adoption studies.