Agriculture plays an important role in the economic growth and food security control in developing countries including Rwanda. This research study was carried out in Kigali and Musanze. Urban farming is one way to best use useless places closed inside household fences, resulting in high yields. Due to their short production cycle, Horticultural crops provide a quick response to emergency food needs, particularly in cities. These species have considerable yields that generate more income for farmers when used appropriately. The main objective of this study was to analyze the factors influencing urban farming production, profitability, and contribution to the households’ livelihoods in Rwanda. The population of interest for this research study constituted smallholder farmers of vegetables and fruits in Kigali and Musanze cities. The sampling unit was the garden household. A multistage sampling technique was employed involving purposive sampling of four districts Gasabo, Kicukiro, Nyarugenge, and Musanze. The study used a sample frame of 1085 population and a sample size of 112 respondents. The results from the study indicated that ten factors over fourteen have a positive influence on urban farming production while four have a negative influence in the study area. The results also showed that the productive fruits grown are classified into five classes indicated in Figure 1. The results of the study revealed different places/methods used to grow vegetables/species and fruits such as bags, baskets and basins, hanging baskets, old wheels, pallet gardens, open ground, trellises, arches, shelves, fences window box walls. The results displayed that the crops do well in small areas/places closed inside the household’s fences. The results proved that urban farming contributed to the social economy through different parts example malnutrition control, money saving, and food security. The results pointed out that urban farming production is constrained by some challenges such as small owned parcels, lack of urban farming knowledge, lack of technologies, period of crop maturity, lack of capital, lack of awareness, habitation system, and infrastructures. However, urban farming development should be enhanced to maintain national food security and improve income for farmers.