Cercospora leaf spot is caused by Cercospora capcisi is an important disease which reduces the productivity of hot pepper (Capsicum spp.). Field experiment was conducted to evaluate different fungicides and its application frequencies against Cercospora leaf spot in order to select an important fungicides and its application frequency at Bako Agricultural Research Center. The experiment was laid out in randomized complete block design with three replication. Two different fungicides (Mancozeb 80WP and Trust-Cymocop 439.5WP) and four application frequencies (two, three, four and five) times with untreated control were used. Data on disease severity, area under disease progress curve, marketable yield and unmarketable yield of hot pepper were recorded. The result revealed that, both fungicides sprayed control Cercospora leaf spot which is significantly different from untreated check in disease severity, area under disease progress curve (AUDPC) and marketable yield. However, application frequencies of fungicides were not significantly different on disease severity, AUDPC and marketable yield of the plant. Application of Trust Cymocop 439.5WP reduces 26.67% relative yield loss of hot pepper over control check. An economic analysis was done for fungicides and shows feasibility of fungicide application for management of Cercospora leaf spot. Fungicide which has the highest Marginal Rate of Return was used for recommendation. Two times application of Trust-Cymocop 439.5WP was recommended to reduce disease severity and yield loss of the plant. Keywords: Cercospora leaf spot, frequency, hot pepper, and trust-Cymocop 439.5WP DOI : 10.7176/JBAH/9-20-01 Publication date :October 31 st 2019