In recent years, Blockchain technology has been recognized as one of the most important new technologies affecting businesses and society, with a very bright future ahead. This technology has been known as one of the most critical technologies of industry 4. Given that Blockchain technology is a new concept before implementing it, the organization must understand it and be prepared to accept it; otherwise, it will fail and cause irreparable damage to the organization. The main purpose of this study is to provide a framework by which organizations can evaluate their readiness to implement Blockchain technology. For this purpose, after a library study and systematic literature review, this study provided the initial research framework using the meta-synthesis method. Finally, this paper used the Lawshe model to validate the proposed framework for the organization's readiness to implement Blockchain technology. Based on the findings, the final framework includes seven main dimensions, including Blockchain-based business strategy, Operations of a distributed system, culture, People in Blockchain decentralized network, decentralized governance, technology, and Blockchain-based product traceability. Besides, 37 main criteria affected these dimensions, and it can help companies increase the level of Blockchain technology readiness. Finally, this framework is used to measure the readiness of an airline company. According to the analysis results of the analysis, Blockchain-based business strategy, culture, and Blockchain-based product traceability have a medium level of readiness. Moreover, none of the main dimensions of Blockchain technology readiness have sufficient readiness in this case study. This paper suggests practical recommendations to improve the level of Blockchain technology readiness for the managers