The paper deals with the issues of pharmacotherapy of larynx chronic diseases in patients with COPD, the use of the acoustic voice characteristics for assessment of the functional state of larynx using a software package SpectaPLUS. Complex treatment of chronic laryngitis, different from the traditional drug therapy, involves voice rest and phonopedic training containing the rational psychotherapy, breath correction, strengthening of voice recovery skills. In addition to indirect laryngoscopy, visualization techniques included inspection with rigid and flexible endoscopes, stroboscope inspection. The identified changes had the form of diffuse hyperemia of the mucous larynx and (or) of the true vocal cords, thickening thereof, rounded medial edge of the true vocal cords. The front third of the folds often featured with the typical «mucous bridges» or the mucus was located diffusely in all parts of the larynx, in some patients phonation process involved false vocal folds. Stroboscopic signs included low amplitude of the vocal folds fluctuation, phase asymmetry, a small symptom of mucosal wave, with the most intense manifestation of these symptoms in hyperplastic laryngitises. Reexamination of the patients was conducted 1.5 months after the end of treatment. Most of the patients indicated the positive trend in the treatment, both in terms of endoscopic pattern and phonatory function. It was found that such factors as maximum phonation time, voicenoise areas dynamically reflect the improved phonation function of larynx on the background of complex therapeutic correction of the upper respiratory tract diseases. In contrast, the frequency of the pitch is a more stable parameter; it is not subject to statistically significant changes. The authors established the relationship between the efficiency of chronic laryngitis treatment and the frequency of COPD aggravation.