New technical capabilities have brought about the sweeping growth of the amount of data acquired by the astronomers from observations with different instruments in various parts of the electromagnetic spectrum. We consider conceptual approach to be a promising tool to efficiently deal with these data. It uses problem domain knowledge to formulate the tasks and develop problem-solving algorithms and data analysis methods in terms of domain concepts without reference to particular data sources, and thereby allows solving certain problems in general form. We demonstrate the benefits of conceptual approach by using it to solve problems related to search for secondary photometric standard candidates, determination of galaxy redshifts, creation of a binary and multiple star repository based on inhomogeneous databases, and classification of eclipsing binaries.We formulate and solve these problems over specifications of astronomical knowledge units such as photometric systems, astronomical objects, multiple stars, etc., and define them in terms of the corresponding problem domains independently of the existing data resources.