This research attempts to study the Supplier Selection and Order Allocation Problem (SSOAP) considering three crucial concepts, namely responsiveness, sustainability, and resilience. To do so, the current research develops a Multi-Stage Decision-Making Framework (MSDMF) to select potential suppliers and determine the quantity of orders. The first stage aims at computing the scores of the suppliers based on several indicators. To do this, a novel decision-making approach named the Stochastic Fuzzy Best–Worst Method (SFBWM) is developed. Then, in the second stage, a Multi-Objective Model (MOM) is suggested to deal with supplier selection and order allocation decisions. In the next step, a data-driven Fuzzy Robust Stochastic (FRS) optimization approach, based on the fuzzy robust stochastic method and the Seasonal Autoregressive Integrated Moving Average (SARIMA) methods, is employed to efficiently treat the hybrid uncertainty of the problem. Afterwards, a novel solution method named the developed Chebyshev Multi-Choice Goal Programming with Utility Function (CMCGP-UF) is developed to obtain the optimal solution. Moreover, given the crucial role of the Medical Equipment (ME) industry in society’s health, especially during the recent Coronavirus disease, this important industry is taken into account. The outcomes of the first stage demonstrate that agility, cost, GHG emission, quality, robustness, and Waste Management (WM), respectively, are the most important criteria. The outcomes of the second stage determine the selected suppliers, utilized transportation systems, and established sites. It is also revealed that demand directly affects all the objective functions while increasing the rate of disruptions has a negative effect on the sustainability measures.